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The map label for this gene is yicO [C]

Identifier: 21674313

GI number: 21674313

Start: 1397113

End: 1398414

Strand: Direct

Name: yicO [C]

Synonym: CT1493

Alternate gene names: 21674313

Gene position: 1397113-1398414 (Clockwise)

Preceding gene: 21674311

Following gene: 21674314

Centisome position: 64.83

GC content: 59.83

Gene sequence:

>1302_bases
ATGCGGAATTTCTTCGAATTCGACAGGCACGGGACGAGTTACCAGCAGGAGGTTCTGGCGGGGCTGACCACCTTTTTCAC
GCTTTCCTACATCATCGTCGTCAACCCGGCCATCCTCGAAGCCACCGGGATGCCGCGCGGCGCTTCGATGACCGCAACCA
TCCTGACAGCGGTGTTCGGCACGGTGCTGATGGGCCTGTATGCAAAGCGCCCCTTCGCCGTCGCGCCCTACATGGGCGAA
AACGCCTTCATCGCCTATACGGTGGTCAAGACGCTTGGCTACTCCTGGCAGACCGCACTCGGCGCCATTCTGGTCAGCGG
TGTGCTCTTCACGCTCATCACGCTCACCGGAGCACGAAAATGGCTGGCCGAAGCGATACCGATGACCCTCAAGCACAGCT
TCACGGTAGGCATAGGCCTTTTCCTCGCTTTCCTCGGTCTTTCCAACATGGGCGTGGTTGCACTCGGCGTGCCCGGAGCT
CCGGTGAAGCTCGGCGATCTGACGACAATTCCGGCACTCTGCGGCCTTGGTGGTCTGGCGCTCACTGGTGCGCTGCTCGT
GCGCAAAGTCACCGGCGCGCTCGTGATCGGCATGGCTGCAACGACAATGCTGATGCTCTCGTTCGGTTTGCTGCAACTTC
CCCAAACCCTCTTCAGCCTGCCGCCTTCGATCGCGCCGCTATGGCTCCAGGTCGACATTACCGGCGCCCTCACCTGGGGC
TTCGTCGGCGTAATCCTGAGCGTGCTGGTGATGGATTTCGTCGACACGATGGGCACGTTGATAGGTCTCTCCGCTCGCGC
CCGGCTGCTCGACGAGAACGGCAACCTGCCGGAGATAGAAAAGCCGATGCTGGTCGATGCGCTCTCGACCACAGCCGCCG
CACTCTTCGGCACCACAACTGCAGGGGTATTCATCGAATCGGCCTCGGGCATCGAACAGGGCGGCAAGACCGGCTTCACG
GCACTCGTGGTGGCAGGCTTGTTCCTGCTTGCCCTCTTTTTCGCGCCGATCCTGACCATTGTGCCGCCACAGGCTTACGG
GCCGGTGCTCGTACTGGTGGGCATGTTCATGATCGAATCTGCGGGTTACTTCGATTTCAACGACTATACCGAGCTGCTCC
CCGCCTTCCTGACCATCGTCATGATGCTCTTCACCTTCAATATCGGCGTCGGTATCACGATGGGCTTCATCAGCTGGGTC
GTCATCAAGGCGCTAGCGGGAAGATTCCGCGAGATCAATGCTGGCATGACCGCGCTGGCGATCCTCTCCGCAACCTTCTA
TATTTTCTATCCTTACCATTAA

Upstream 100 bases:

>100_bases
TTAATGCGATTTGAATCTTTGCCGGAATGCTCAACGGTACAAAGTCTGTCGCATTATTCGTACTTTTCAACTTAACCATA
ACGTGTTTGCTATCAAGACC

Downstream 100 bases:

>100_bases
GAGAACCGATGCTCAAGTCAAAGCTCAGAATCGTTCAGGCCGACTGCACGCTGGCCAATTTCGAGGAAAATCTCGAACGC
CACATCAAAGCCATCGAAAC

Product: xanthine/uracil permease family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 433

Protein sequence:

>433_residues
MRNFFEFDRHGTSYQQEVLAGLTTFFTLSYIIVVNPAILEATGMPRGASMTATILTAVFGTVLMGLYAKRPFAVAPYMGE
NAFIAYTVVKTLGYSWQTALGAILVSGVLFTLITLTGARKWLAEAIPMTLKHSFTVGIGLFLAFLGLSNMGVVALGVPGA
PVKLGDLTTIPALCGLGGLALTGALLVRKVTGALVIGMAATTMLMLSFGLLQLPQTLFSLPPSIAPLWLQVDITGALTWG
FVGVILSVLVMDFVDTMGTLIGLSARARLLDENGNLPEIEKPMLVDALSTTAAALFGTTTAGVFIESASGIEQGGKTGFT
ALVVAGLFLLALFFAPILTIVPPQAYGPVLVLVGMFMIESAGYFDFNDYTELLPAFLTIVMMLFTFNIGVGITMGFISWV
VIKALAGRFREINAGMTALAILSATFYIFYPYH

Sequences:

>Translated_433_residues
MRNFFEFDRHGTSYQQEVLAGLTTFFTLSYIIVVNPAILEATGMPRGASMTATILTAVFGTVLMGLYAKRPFAVAPYMGE
NAFIAYTVVKTLGYSWQTALGAILVSGVLFTLITLTGARKWLAEAIPMTLKHSFTVGIGLFLAFLGLSNMGVVALGVPGA
PVKLGDLTTIPALCGLGGLALTGALLVRKVTGALVIGMAATTMLMLSFGLLQLPQTLFSLPPSIAPLWLQVDITGALTWG
FVGVILSVLVMDFVDTMGTLIGLSARARLLDENGNLPEIEKPMLVDALSTTAAALFGTTTAGVFIESASGIEQGGKTGFT
ALVVAGLFLLALFFAPILTIVPPQAYGPVLVLVGMFMIESAGYFDFNDYTELLPAFLTIVMMLFTFNIGVGITMGFISWV
VIKALAGRFREINAGMTALAILSATFYIFYPYH
>Mature_433_residues
MRNFFEFDRHGTSYQQEVLAGLTTFFTLSYIIVVNPAILEATGMPRGASMTATILTAVFGTVLMGLYAKRPFAVAPYMGE
NAFIAYTVVKTLGYSWQTALGAILVSGVLFTLITLTGARKWLAEAIPMTLKHSFTVGIGLFLAFLGLSNMGVVALGVPGA
PVKLGDLTTIPALCGLGGLALTGALLVRKVTGALVIGMAATTMLMLSFGLLQLPQTLFSLPPSIAPLWLQVDITGALTWG
FVGVILSVLVMDFVDTMGTLIGLSARARLLDENGNLPEIEKPMLVDALSTTAAALFGTTTAGVFIESASGIEQGGKTGFT
ALVVAGLFLLALFFAPILTIVPPQAYGPVLVLVGMFMIESAGYFDFNDYTELLPAFLTIVMMLFTFNIGVGITMGFISWV
VIKALAGRFREINAGMTALAILSATFYIFYPYH

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=424, Percent_Identity=40.3301886792453, Blast_Score=311, Evalue=4e-86,
Organism=Escherichia coli, GI1790150, Length=433, Percent_Identity=38.3371824480369, Blast_Score=287, Evalue=8e-79,
Organism=Escherichia coli, GI1790499, Length=436, Percent_Identity=34.8623853211009, Blast_Score=237, Evalue=1e-63,
Organism=Escherichia coli, GI48994909, Length=438, Percent_Identity=34.9315068493151, Blast_Score=233, Evalue=2e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 45991; Mature: 45991

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNFFEFDRHGTSYQQEVLAGLTTFFTLSYIIVVNPAILEATGMPRGASMTATILTAVFG
CCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCCCCCCHHHHHHHHHHHH
TVLMGLYAKRPFAVAPYMGENAFIAYTVVKTLGYSWQTALGAILVSGVLFTLITLTGARK
HHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WLAEAIPMTLKHSFTVGIGLFLAFLGLSNMGVVALGVPGAPVKLGDLTTIPALCGLGGLA
HHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCCHHHHHHHCCCHHH
LTGALLVRKVTGALVIGMAATTMLMLSFGLLQLPQTLFSLPPSIAPLWLQVDITGALTWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHH
FVGVILSVLVMDFVDTMGTLIGLSARARLLDENGNLPEIEKPMLVDALSTTAAALFGTTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHH
AGVFIESASGIEQGGKTGFTALVVAGLFLLALFFAPILTIVPPQAYGPVLVLVGMFMIES
HHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
AGYFDFNDYTELLPAFLTIVMMLFTFNIGVGITMGFISWVVIKALAGRFREINAGMTALA
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ILSATFYIFYPYH
HHHHHHHEEECCC
>Mature Secondary Structure
MRNFFEFDRHGTSYQQEVLAGLTTFFTLSYIIVVNPAILEATGMPRGASMTATILTAVFG
CCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHEECCCCCCCHHHHHHHHHHHH
TVLMGLYAKRPFAVAPYMGENAFIAYTVVKTLGYSWQTALGAILVSGVLFTLITLTGARK
HHHHHHHHCCCCEECCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
WLAEAIPMTLKHSFTVGIGLFLAFLGLSNMGVVALGVPGAPVKLGDLTTIPALCGLGGLA
HHHHHHCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCEECCCCHHHHHHHCCCHHH
LTGALLVRKVTGALVIGMAATTMLMLSFGLLQLPQTLFSLPPSIAPLWLQVDITGALTWG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEHHHHHHH
FVGVILSVLVMDFVDTMGTLIGLSARARLLDENGNLPEIEKPMLVDALSTTAAALFGTTT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCHH
AGVFIESASGIEQGGKTGFTALVVAGLFLLALFFAPILTIVPPQAYGPVLVLVGMFMIES
HHHEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHC
AGYFDFNDYTELLPAFLTIVMMLFTFNIGVGITMGFISWVVIKALAGRFREINAGMTALA
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ILSATFYIFYPYH
HHHHHHHEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]