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The map label for this gene is hrcA

Identifier: 21674306

GI number: 21674306

Start: 1391164

End: 1392234

Strand: Reverse

Name: hrcA

Synonym: CT1486

Alternate gene names: 21674306

Gene position: 1392234-1391164 (Counterclockwise)

Preceding gene: 21674307

Following gene: 21674305

Centisome position: 64.61

GC content: 57.98

Gene sequence:

>1071_bases
ATGAATTATCGTGATTTGACCCTGCGTGAACGTCAGGTTCTCGGTATTATCATACAGTCGTACGTCGTTTCGGCGATGCC
GGTCGGTTCGCGTACCATCGCGCGAAACTATAACCTCGGCCTGTCGGACGCTACCATTCGCAACGTCATGGCCGACCTGG
AGGCGGATGGATTCATCAGCCAGCCGCACACCTCCGCCGGTCGGGTGCCGACCGACAAGGGGTATCGCTATTACGTCGAT
CTGATCATGAACGTCAGCCGGATTGATGAAGAGGAAAAGCGGATGATCGACGATCGTTTCAGCAATCGCAATTCGGAGCT
GAAGGGCACCTCCGCCGAAGTGCTGGGCACGGCGGCGCGGGTTCTGGGCAGCATTTCGCGACAGCTCGCCGTGGTGCTGC
CGCCGAGGCTCTCCAACGCGGTTTTCGAACGGCTTGATATTGTGCAGCTCGCCTCGTCGCGGATCATGGTGGTTATTGCC
ATCCAGTCGCTTTTTGTCAAGACCATCGTCATGGAGCTGAACGCGGAAATATCCCGGCAGAAGATCGACGCCGTGGTCGA
TGTGCTCAATGAACGCCTGCCGGGGCTGACGCTCGAAGAGATTCGCAGCACCATCGCCCAGCGCCTTTCGGACTTCAAGG
GCAGCGAAGAGCTCATGAACAGCATCGTCAGCTCGGCTGACACGCTTTTCGATGAATCCTCCATTCTCGAACAGCTCTAT
GTTTCGGGCACCGAGAACATCGTTGATCAGCCCGAGTTCAAACAGCCAGAGAAGGTGCGCGACATCATCACCATGATCGA
GGACAAGTTCGGCATGGCCAGGCTTGTCGATAACGCGGTCCCCTCGGCGCTTCGCCAGGTCAGCGAGTGCGAGGTGGCCA
TCAGCATCGGCACCGAGAACCGCACGGGCAAGGCCGCCGACCTGACCATTGTTTCGTCGCCCTACTTCGCGGGCAAGATG
ATTGGCAGAGTTGGCGTCATGGGGCCGAAGCGGATGAATTACGAACACGCCGTGCGCGTAGTGAACTACATGGCGGGCTG
CCTTTCAGAGGCGCTCTCCGGAAATAATTAA

Upstream 100 bases:

>100_bases
CAACTATCAGGGAGCTTTCGCTGTTAATGCATATCGGCCCCAAATAGCTTTGCCGCGCCGATTCGCGCGGAATCAGTTTC
AAGTTACAGGCGGTTTCCAG

Downstream 100 bases:

>100_bases
TTTTAAATATTTTTTCGTCATTATGAGCAGAAAGCACCACAAGGAACAGGAAGAGATACAGGAGCAGGAGACGATCAGCG
CTGGGGCGGCTGAAACGCCT

Product: heat-inducible transcription repressor HrcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 356

Protein sequence:

>356_residues
MNYRDLTLRERQVLGIIIQSYVVSAMPVGSRTIARNYNLGLSDATIRNVMADLEADGFISQPHTSAGRVPTDKGYRYYVD
LIMNVSRIDEEEKRMIDDRFSNRNSELKGTSAEVLGTAARVLGSISRQLAVVLPPRLSNAVFERLDIVQLASSRIMVVIA
IQSLFVKTIVMELNAEISRQKIDAVVDVLNERLPGLTLEEIRSTIAQRLSDFKGSEELMNSIVSSADTLFDESSILEQLY
VSGTENIVDQPEFKQPEKVRDIITMIEDKFGMARLVDNAVPSALRQVSECEVAISIGTENRTGKAADLTIVSSPYFAGKM
IGRVGVMGPKRMNYEHAVRVVNYMAGCLSEALSGNN

Sequences:

>Translated_356_residues
MNYRDLTLRERQVLGIIIQSYVVSAMPVGSRTIARNYNLGLSDATIRNVMADLEADGFISQPHTSAGRVPTDKGYRYYVD
LIMNVSRIDEEEKRMIDDRFSNRNSELKGTSAEVLGTAARVLGSISRQLAVVLPPRLSNAVFERLDIVQLASSRIMVVIA
IQSLFVKTIVMELNAEISRQKIDAVVDVLNERLPGLTLEEIRSTIAQRLSDFKGSEELMNSIVSSADTLFDESSILEQLY
VSGTENIVDQPEFKQPEKVRDIITMIEDKFGMARLVDNAVPSALRQVSECEVAISIGTENRTGKAADLTIVSSPYFAGKM
IGRVGVMGPKRMNYEHAVRVVNYMAGCLSEALSGNN
>Mature_356_residues
MNYRDLTLRERQVLGIIIQSYVVSAMPVGSRTIARNYNLGLSDATIRNVMADLEADGFISQPHTSAGRVPTDKGYRYYVD
LIMNVSRIDEEEKRMIDDRFSNRNSELKGTSAEVLGTAARVLGSISRQLAVVLPPRLSNAVFERLDIVQLASSRIMVVIA
IQSLFVKTIVMELNAEISRQKIDAVVDVLNERLPGLTLEEIRSTIAQRLSDFKGSEELMNSIVSSADTLFDESSILEQLY
VSGTENIVDQPEFKQPEKVRDIITMIEDKFGMARLVDNAVPSALRQVSECEVAISIGTENRTGKAADLTIVSSPYFAGKM
IGRVGVMGPKRMNYEHAVRVVNYMAGCLSEALSGNN

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_CHLTE (Q8KCD6)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_662371.1
- ProteinModelPortal:   Q8KCD6
- SMR:   Q8KCD6
- GeneID:   1006031
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1486
- NMPDR:   fig|194439.1.peg.1465
- TIGR:   CT1486
- HOGENOM:   HBG729878
- OMA:   LEQPHTS
- ProtClustDB:   CLSK637786
- BioCyc:   CTEP194439:CT_1486-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF01628 HrcA

EC number: NA

Molecular weight: Translated: 39390; Mature: 39390

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYRDLTLRERQVLGIIIQSYVVSAMPVGSRTIARNYNLGLSDATIRNVMADLEADGFIS
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCC
QPHTSAGRVPTDKGYRYYVDLIMNVSRIDEEEKRMIDDRFSNRNSELKGTSAEVLGTAAR
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
VLGSISRQLAVVLPPRLSNAVFERLDIVQLASSRIMVVIAIQSLFVKTIVMELNAEISRQ
HHHHHHHHEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KIDAVVDVLNERLPGLTLEEIRSTIAQRLSDFKGSEELMNSIVSSADTLFDESSILEQLY
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VSGTENIVDQPEFKQPEKVRDIITMIEDKFGMARLVDNAVPSALRQVSECEVAISIGTEN
HCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCC
RTGKAADLTIVSSPYFAGKMIGRVGVMGPKRMNYEHAVRVVNYMAGCLSEALSGNN
CCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNYRDLTLRERQVLGIIIQSYVVSAMPVGSRTIARNYNLGLSDATIRNVMADLEADGFIS
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCHHHHHHHHHHHCCCCCCC
QPHTSAGRVPTDKGYRYYVDLIMNVSRIDEEEKRMIDDRFSNRNSELKGTSAEVLGTAAR
CCCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
VLGSISRQLAVVLPPRLSNAVFERLDIVQLASSRIMVVIAIQSLFVKTIVMELNAEISRQ
HHHHHHHHEEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
KIDAVVDVLNERLPGLTLEEIRSTIAQRLSDFKGSEELMNSIVSSADTLFDESSILEQLY
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VSGTENIVDQPEFKQPEKVRDIITMIEDKFGMARLVDNAVPSALRQVSECEVAISIGTEN
HCCCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCC
RTGKAADLTIVSSPYFAGKMIGRVGVMGPKRMNYEHAVRVVNYMAGCLSEALSGNN
CCCCCEEEEEEECCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901