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The map label for this gene is degT [H]

Identifier: 21674297

GI number: 21674297

Start: 1383958

End: 1385073

Strand: Reverse

Name: degT [H]

Synonym: CT1477

Alternate gene names: 21674297

Gene position: 1385073-1383958 (Counterclockwise)

Preceding gene: 21674301

Following gene: 21674292

Centisome position: 64.27

GC content: 61.83

Gene sequence:

>1116_bases
ATGCAGTTCATCGACCTCATAACCCAGAAAAACCGCATCCGCGAGAACCTCATGAAGCGTATCGAGCGGATCATCGACAG
CGCCCAGTTCGTCATGGGTCCCGAAGTGCTCGAAGCCGAGAAAAAGCTTGCCGAGTACGTCGGCACGAAGCACTGTGTTT
CGTGCGCCTCCGGCACCGACGCGCTGCTCATTCCGCTTATGGCCAAGGGCATCGGCCCCGGAGACGCGGTGCTCACCACG
CCGTTCACCTTCGTGGCCACCGCTGAGGTCGTCAGCCTTGTGGGCGCGACGCCGGTGTTCGTCGATGTGCTGCCCGGTAC
CTTCAACATCAACCCTGATGGCGTCGCCCCGGCGGTCGAAGAGGCGCGCAAAAAGGGGTTAAATCCGAAAGCCCTGATTC
CAGTCGATTTGTTCGGCTTGCCCGCCGAGTACGACCGCCTCGAAAAGGTGGCAGCCGAGCAGGGACTCTGGATTCTCGAA
GACGCCGCGCAGGGCTTCGGCGGCACGGTCGGCGGCAGGAGGGCGGGCAGCTTCGGCCTTGTCGGCGCGACCTCATTCTT
CCCGGCCAAGCCGCTCGGCTGCTACGGCGATGGCGGCGCGATTTTCACCAACGACGACGAGCTGCTTGAACTGCTGATCT
CCGTGCGCGTGCACGGCGGCGGTTCGGACAAATACAACAACGAGCGCATCGGCCTCAACGGCCGCTTCGACGCCATCCAG
GCGGCAGTCATCAACGAAAAACTCACCATCTTCGACGACGAACTTGACCTGCGCAACAAGGTCGCCGCTGCCTACAGCGC
CCGCCTGAAGGATCGCGTCGTCGTTCCCGAAGTCCCGGAAGGTTACACCTCCTGCTGGGCGCAATACTCCGTGCTCGCCA
ACTCCACCGACGACCGCACGAAGCTCATGGCCGCGCTGAAGGACGCGGGCATCCCCTCGGCGATCTACTATCCGATCCCG
CTGCACCTCCAGAAAGCCTACGAAAATCTCGGCTACAAACCCGGCGACTTCCCGGTCTCGGAAGATTTCAGCGCGAGGGT
TTTTGCTCTGCCGATGCATCCGTATCTGAAGGAAGAGGAGATCGAGCAGATTTGCAGGGTGATTACGAGGGCGTGA

Upstream 100 bases:

>100_bases
AACACAGCGCTGTCTGTTCGAACTTTCGGGATTGAGTCGATGAATCCGTATAATATCAAATCGAATTTTTTCAGGAACAT
CATCTTAGCCCAATAAAATT

Downstream 100 bases:

>100_bases
GAAATTGCCGGGAGCGTTCGACGGTGTAGCAGCCGAAGCCGTCGGCGCTCCCGGCATCACCAATGCTACGTTGGAAAAGA
TTGGCGGGGATCACATTGTG

Product: DegT/DnrJ/EryC1/StrS family protein

Products: TDP-D-fucosamine; 2-oxoglutarate [C]

Alternate protein names: NA

Number of amino acids: Translated: 371; Mature: 371

Protein sequence:

>371_residues
MQFIDLITQKNRIRENLMKRIERIIDSAQFVMGPEVLEAEKKLAEYVGTKHCVSCASGTDALLIPLMAKGIGPGDAVLTT
PFTFVATAEVVSLVGATPVFVDVLPGTFNINPDGVAPAVEEARKKGLNPKALIPVDLFGLPAEYDRLEKVAAEQGLWILE
DAAQGFGGTVGGRRAGSFGLVGATSFFPAKPLGCYGDGGAIFTNDDELLELLISVRVHGGGSDKYNNERIGLNGRFDAIQ
AAVINEKLTIFDDELDLRNKVAAAYSARLKDRVVVPEVPEGYTSCWAQYSVLANSTDDRTKLMAALKDAGIPSAIYYPIP
LHLQKAYENLGYKPGDFPVSEDFSARVFALPMHPYLKEEEIEQICRVITRA

Sequences:

>Translated_371_residues
MQFIDLITQKNRIRENLMKRIERIIDSAQFVMGPEVLEAEKKLAEYVGTKHCVSCASGTDALLIPLMAKGIGPGDAVLTT
PFTFVATAEVVSLVGATPVFVDVLPGTFNINPDGVAPAVEEARKKGLNPKALIPVDLFGLPAEYDRLEKVAAEQGLWILE
DAAQGFGGTVGGRRAGSFGLVGATSFFPAKPLGCYGDGGAIFTNDDELLELLISVRVHGGGSDKYNNERIGLNGRFDAIQ
AAVINEKLTIFDDELDLRNKVAAAYSARLKDRVVVPEVPEGYTSCWAQYSVLANSTDDRTKLMAALKDAGIPSAIYYPIP
LHLQKAYENLGYKPGDFPVSEDFSARVFALPMHPYLKEEEIEQICRVITRA
>Mature_371_residues
MQFIDLITQKNRIRENLMKRIERIIDSAQFVMGPEVLEAEKKLAEYVGTKHCVSCASGTDALLIPLMAKGIGPGDAVLTT
PFTFVATAEVVSLVGATPVFVDVLPGTFNINPDGVAPAVEEARKKGLNPKALIPVDLFGLPAEYDRLEKVAAEQGLWILE
DAAQGFGGTVGGRRAGSFGLVGATSFFPAKPLGCYGDGGAIFTNDDELLELLISVRVHGGGSDKYNNERIGLNGRFDAIQ
AAVINEKLTIFDDELDLRNKVAAAYSARLKDRVVVPEVPEGYTSCWAQYSVLANSTDDRTKLMAALKDAGIPSAIYYPIP
LHLQKAYENLGYKPGDFPVSEDFSARVFALPMHPYLKEEEIEQICRVITRA

Specific function: This membrane protein may function as a sensor protein and may transfer the signal of environmental stimuli to the regulatory region of target genes to activate or repress transcription of the genes [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI2367285, Length=328, Percent_Identity=30.1829268292683, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI145693159, Length=362, Percent_Identity=27.3480662983425, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 40256; Mature: 40256

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFIDLITQKNRIRENLMKRIERIIDSAQFVMGPEVLEAEKKLAEYVGTKHCVSCASGTD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHCCCCC
ALLIPLMAKGIGPGDAVLTTPFTFVATAEVVSLVGATPVFVDVLPGTFNINPDGVAPAVE
HHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCEEEEECCCEECCCCCCCCHHHH
EARKKGLNPKALIPVDLFGLPAEYDRLEKVAAEQGLWILEDAAQGFGGTVGGRRAGSFGL
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCCCCCCCCE
VGATSFFPAKPLGCYGDGGAIFTNDDELLELLISVRVHGGGSDKYNNERIGLNGRFDAIQ
EECCCCCCCCCCCEECCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCHHHHH
AAVINEKLTIFDDELDLRNKVAAAYSARLKDRVVVPEVPEGYTSCWAQYSVLANSTDDRT
HHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHCCCCCHHH
KLMAALKDAGIPSAIYYPIPLHLQKAYENLGYKPGDFPVSEDFSARVFALPMHPYLKEEE
HHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCHHH
IEQICRVITRA
HHHHHHHHHCC
>Mature Secondary Structure
MQFIDLITQKNRIRENLMKRIERIIDSAQFVMGPEVLEAEKKLAEYVGTKHCVSCASGTD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHCCCCC
ALLIPLMAKGIGPGDAVLTTPFTFVATAEVVSLVGATPVFVDVLPGTFNINPDGVAPAVE
HHHHHHHHCCCCCCCCEEECCHHHHHHHHHHHHHCCCCEEEEECCCEECCCCCCCCHHHH
EARKKGLNPKALIPVDLFGLPAEYDRLEKVAAEQGLWILEDAAQGFGGTVGGRRAGSFGL
HHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHHCCCEEEEHHHHCCCCCCCCCCCCCCCE
VGATSFFPAKPLGCYGDGGAIFTNDDELLELLISVRVHGGGSDKYNNERIGLNGRFDAIQ
EECCCCCCCCCCCEECCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCHHHHH
AAVINEKLTIFDDELDLRNKVAAAYSARLKDRVVVPEVPEGYTSCWAQYSVLANSTDDRT
HHHHCCCEEEECCCHHHHHHHHHHHHHHHHCCEECCCCCCHHHHHHHHHHHHCCCCCHHH
KLMAALKDAGIPSAIYYPIPLHLQKAYENLGYKPGDFPVSEDFSARVFALPMHPYLKEEE
HHHHHHHHCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCCHHH
IEQICRVITRA
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: dTDP-4-dehydro-6-deoxy-D-glucose; L-glutamate [C]

Specific reaction: dTDP-4-dehydro-6-deoxy-D-glucose + L-glutamate = TDP-D-fucosamine + 2-oxoglutarate [C]

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2104607 [H]