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The map label for this gene is fur [H]

Identifier: 21674276

GI number: 21674276

Start: 1366130

End: 1366621

Strand: Direct

Name: fur [H]

Synonym: CT1455

Alternate gene names: 21674276

Gene position: 1366130-1366621 (Clockwise)

Preceding gene: 21674270

Following gene: 21674277

Centisome position: 63.4

GC content: 57.52

Gene sequence:

>492_bases
GTGAAACAAACGGGCAGCGACACGATCGCAAAGGTCGAAGCGCTTTTCAAATCGTACATGAAGGAGGAGGGGCTCCGCTG
CACCCAGGAGCGCCTGAGCGTGCTCAGAGAGATGTATGGCTCCAGCACCCACCTTGACGCCGACGAGCTCTTTGTCCGGC
TGCGTAAAAAAGGAGTTGCCATTTCACGCGCCACGGTGTACCACACCCTTGACCTGCTCTTCAGGTTCAACCTCGTCACC
AAGATCGATCTCGGCCATAAGCACACCCACTACGAAAAATCCTGGGGCGTGACCAACCACCTGCACATCATCTGTCTGAA
ATGCGGACACGTTTCGGAGGCCACGAGCTGCGAGCTGCCGGAATTGATGGAAACGCTCTGCGTCGGGCACGGCTACTCGC
TCGGCAGTTTCAGCCTGCAACTCTTTGGCGAGTGCGCAGACAAGGAGGCCTGCGCCCGGCGCATCAGCAACAAGCACAAA
GAGAAAACCTGA

Upstream 100 bases:

>100_bases
GGCTCTTCCCGCTCCGCCGCCTTCATGGTTCACAGGGAATTCGCAGAAAAACAATACATTAGAAAAACCGAAAACACAAA
ATACTGACAGCAAGAACATC

Downstream 100 bases:

>100_bases
AATCCGGACACCATGCCCTGGCTCTATCTGATCCTCGCCATCATCGCCGAAGTCTCCGGCACCACCAGCATGAAGCTCTC
GGCAGGCTTCACCAAGCCGG

Product: ferric uptake regulator family protein

Products: NA

Alternate protein names: Ferric uptake regulator [H]

Number of amino acids: Translated: 163; Mature: 163

Protein sequence:

>163_residues
MKQTGSDTIAKVEALFKSYMKEEGLRCTQERLSVLREMYGSSTHLDADELFVRLRKKGVAISRATVYHTLDLLFRFNLVT
KIDLGHKHTHYEKSWGVTNHLHIICLKCGHVSEATSCELPELMETLCVGHGYSLGSFSLQLFGECADKEACARRISNKHK
EKT

Sequences:

>Translated_163_residues
MKQTGSDTIAKVEALFKSYMKEEGLRCTQERLSVLREMYGSSTHLDADELFVRLRKKGVAISRATVYHTLDLLFRFNLVT
KIDLGHKHTHYEKSWGVTNHLHIICLKCGHVSEATSCELPELMETLCVGHGYSLGSFSLQLFGECADKEACARRISNKHK
EKT
>Mature_163_residues
MKQTGSDTIAKVEALFKSYMKEEGLRCTQERLSVLREMYGSSTHLDADELFVRLRKKGVAISRATVYHTLDLLFRFNLVT
KIDLGHKHTHYEKSWGVTNHLHIICLKCGHVSEATSCELPELMETLCVGHGYSLGSFSLQLFGECADKEACARRISNKHK
EKT

Specific function: Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes [H]

COG id: COG0735

COG function: function code P; Fe2+/Zn2+ uptake regulation proteins

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Fur family [H]

Homologues:

None

Paralogues:

None

Copy number: 3432 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002481 [H]

Pfam domain/function: PF01475 FUR [H]

EC number: NA

Molecular weight: Translated: 18491; Mature: 18491

Theoretical pI: Translated: 8.30; Mature: 8.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
4.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQTGSDTIAKVEALFKSYMKEEGLRCTQERLSVLREMYGSSTHLDADELFVRLRKKGVA
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCH
ISRATVYHTLDLLFRFNLVTKIDLGHKHTHYEKSWGVTNHLHIICLKCGHVSEATSCELP
HHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHCCCCCCEEEEEEECCCCCCCCCCCHH
ELMETLCVGHGYSLGSFSLQLFGECADKEACARRISNKHKEKT
HHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKQTGSDTIAKVEALFKSYMKEEGLRCTQERLSVLREMYGSSTHLDADELFVRLRKKGVA
CCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCH
ISRATVYHTLDLLFRFNLVTKIDLGHKHTHYEKSWGVTNHLHIICLKCGHVSEATSCELP
HHHHHHHHHHHHHHHHHHHHEECCCCCCCCCHHHCCCCCCEEEEEEECCCCCCCCCCCHH
ELMETLCVGHGYSLGSFSLQLFGECADKEACARRISNKHKEKT
HHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8083178 [H]