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The map label for this gene is ppk-2

Identifier: 21673875

GI number: 21673875

Start: 984800

End: 986944

Strand: Direct

Name: ppk-2

Synonym: CT1049

Alternate gene names: 21673875

Gene position: 984800-986944 (Clockwise)

Preceding gene: 21673874

Following gene: 21673876

Centisome position: 45.7

GC content: 55.99

Gene sequence:

>2145_bases
ATGACAGATTCGGAAAACGGGACATTGGTTCCGGCGGCTATAGCCGAGCCGGATCTGCGCGATCCCTTGCTCTACGTGAA
CCGTGAGCTGAGCTGGATCGATTTCAACCAGCGAGTGCTCGAAGAGGCACTCGATTCCGCCGCGCATCCGTTGTTGGAGC
GCGTCAAGTTCCTCTCGATTTTCAGCTCCAACCTCGACGAGTTTTTCATGATCCGCGTGGCGGGACTTGATGACCAGTGC
GCTGCGGGCATCAACGAGCGCTCGGTCGATGGCCTCACGCCTATCGAGATGCTCGAGCGGATTCGCGAGCGCGTCATCGG
CCAGCTCCGGCAGCGCAACGCCTGTTTTTTCGATGATATTCTGCCTGCGCTCAAAAGGAAAGGGATCGAATTCGTCAGTG
TCTCTTCGCTTTCCGTCGAGCAGCAGCAACTTCTTCAGCACTATTTCAGAAAGGAGGTTTTTCCGGTTCTGACGCCGCTC
GCTTTCGATACGGGCCATCCCTTTCCGTTCATGTCCAACCTCTCGCTGAATCTTGCAATCGAGCTTGAGGACGAGGAGAG
CGGAGCGATCAAGTTTGCTCGCGTCAAGGTGCCCGGCATTTTGTCGAGAATCATCCGACTCGACCAGATCGAGGGTCTCG
GCTTCGACGACGGACGGATACGCCTACTGTGGCTCGAAGACCTTGTAGAGCACAACCTCGATCAGCTCTTTCCGAAGATG
CGCATTTTGCAGTGCCACCCATTCAGGATCATCCGTGACGCGGATATCGAGATCGAGGAGGACGAGGCGGGCGATTTGCT
CGAAAGCATCGAACAGGGGGTGCGCTCGCGCCGCTATGGCAAGGTGGTACGTCTCGATATCAATCCCGACATGCCGCACT
CCATCCGGAGCCTCCTCGTCAAGAACCTTGAAACTTACGAGCGGAACGTTTACGAAATTGGCGGCGTGCTCGGCATGAGC
GCGCTGATGGAGCTGCTTAAAATCGACCGGCCTGATCTGAAAGACGAGCTTTTCGTGCCGAACAATCCGCTTGATGACAA
GCGGACTGCTGACATATTTGCTGAAATGCGTTCCGGCGATATGCTGCTGCATCACCCATACGACTCGTTCAAGCCAGTGG
TTGATCTCATCTGGCAGGCGGCGCGCGATCCCGATGTGCTCTCTATCAAGCAGACGCTCTACCGGGTAGGCAGCAACTCG
CCGGTGGTCAAGGCGCTGATGTTCGCCGCCGAGCAGCGCAAGCAGGTGGCGGTGCTGGTCGAGCTCAAGGCAAGGTTTGA
CGAGGAGAACAACATCCTCTGGGCGCGTTCGCTCGAAGATGCTGGAGCGCATGTGGTTTACGGCCTGCCCGGCCTGAAGA
CTCACGCCAAGCTCACGATGATCGTACGGCGTGAGCAGGAGGGACTTCGCCACTACCTGCATCTCGGCACCGGCAACTAT
AACACCGTGACCGCGAGAATCTATACCGATTATAGCTATCTGACGACCGACCCGGTGCTTGCTGACGACGTCACCGAGCT
GTTCAACTCACTGACCGGCTACTCGAAGCATCGCGAATATCGCTCGCTGATCGTTTCTCCGCTTAATATGCGGCGCTGGA
TCATGGAGATGATCCGTCACGAAGTCGACCACCAAAAGCATACCGGCAACGGCAGAATCGTCATGAAGATGAATGCACTG
GTCGATGAGGAGATCATCCGAGCGCTCTACCGCGCCTCGATGGCCGGCGTGAAGATCGATCTGGCCATCCGGGGTATCTG
CTGTCTCAAGCCTGGTATTCCCGGCATCAGCGAAAACATCCGGGTTGTCAGCGTGATCGGTAGATTTCTCGAACACAGCC
GGGTTTATTATTTTAACAATGGAGATCATGCCCGGATTTTTCTGGGCAGTGCTGACATCATGCCGCGTAACCTCGACAAG
CGGGTCGAGACGCTTTTTCCCGTTATTGAGCCGCGCCTGGTTGAATCGATCAAATCCGATCTTGAACTGACCCTGAGCGA
TAACCGCAAATCGTGGGAGATGCAGCCGGACGGAACCTACATCAGAAAACGGGGCGGGCGGCCAGCAGTCGACAGCCAGA
GGCTGTTTATGCGGCGCTCTCTCCGGAGGAAGAAAAACATCAAAAAAAAGGTTAAAGGATTATGA

Upstream 100 bases:

>100_bases
GTTTTCAGGAGGTTCCGTCGGTGCCGTGTGATCCCTGGGACGAGCCGCTCGACATGGTGGTCACAGAAAATGAAATCATC
AATTGCCAGTACAACAGCAA

Downstream 100 bases:

>100_bases
AGATTGCAGTTGGAAGCGATCATGCAGGAGTGGAGCTGAAGAAGTTCGTCCTCTCATGGCTTGAAAAGCATTGCTATGAT
TTCGAGGATATGGGTCCCTA

Product: polyphosphate kinase

Products: NA

Alternate protein names: ATP-polyphosphate phosphotransferase 2; Polyphosphoric acid kinase 2

Number of amino acids: Translated: 714; Mature: 713

Protein sequence:

>714_residues
MTDSENGTLVPAAIAEPDLRDPLLYVNRELSWIDFNQRVLEEALDSAAHPLLERVKFLSIFSSNLDEFFMIRVAGLDDQC
AAGINERSVDGLTPIEMLERIRERVIGQLRQRNACFFDDILPALKRKGIEFVSVSSLSVEQQQLLQHYFRKEVFPVLTPL
AFDTGHPFPFMSNLSLNLAIELEDEESGAIKFARVKVPGILSRIIRLDQIEGLGFDDGRIRLLWLEDLVEHNLDQLFPKM
RILQCHPFRIIRDADIEIEEDEAGDLLESIEQGVRSRRYGKVVRLDINPDMPHSIRSLLVKNLETYERNVYEIGGVLGMS
ALMELLKIDRPDLKDELFVPNNPLDDKRTADIFAEMRSGDMLLHHPYDSFKPVVDLIWQAARDPDVLSIKQTLYRVGSNS
PVVKALMFAAEQRKQVAVLVELKARFDEENNILWARSLEDAGAHVVYGLPGLKTHAKLTMIVRREQEGLRHYLHLGTGNY
NTVTARIYTDYSYLTTDPVLADDVTELFNSLTGYSKHREYRSLIVSPLNMRRWIMEMIRHEVDHQKHTGNGRIVMKMNAL
VDEEIIRALYRASMAGVKIDLAIRGICCLKPGIPGISENIRVVSVIGRFLEHSRVYYFNNGDHARIFLGSADIMPRNLDK
RVETLFPVIEPRLVESIKSDLELTLSDNRKSWEMQPDGTYIRKRGGRPAVDSQRLFMRRSLRRKKNIKKKVKGL

Sequences:

>Translated_714_residues
MTDSENGTLVPAAIAEPDLRDPLLYVNRELSWIDFNQRVLEEALDSAAHPLLERVKFLSIFSSNLDEFFMIRVAGLDDQC
AAGINERSVDGLTPIEMLERIRERVIGQLRQRNACFFDDILPALKRKGIEFVSVSSLSVEQQQLLQHYFRKEVFPVLTPL
AFDTGHPFPFMSNLSLNLAIELEDEESGAIKFARVKVPGILSRIIRLDQIEGLGFDDGRIRLLWLEDLVEHNLDQLFPKM
RILQCHPFRIIRDADIEIEEDEAGDLLESIEQGVRSRRYGKVVRLDINPDMPHSIRSLLVKNLETYERNVYEIGGVLGMS
ALMELLKIDRPDLKDELFVPNNPLDDKRTADIFAEMRSGDMLLHHPYDSFKPVVDLIWQAARDPDVLSIKQTLYRVGSNS
PVVKALMFAAEQRKQVAVLVELKARFDEENNILWARSLEDAGAHVVYGLPGLKTHAKLTMIVRREQEGLRHYLHLGTGNY
NTVTARIYTDYSYLTTDPVLADDVTELFNSLTGYSKHREYRSLIVSPLNMRRWIMEMIRHEVDHQKHTGNGRIVMKMNAL
VDEEIIRALYRASMAGVKIDLAIRGICCLKPGIPGISENIRVVSVIGRFLEHSRVYYFNNGDHARIFLGSADIMPRNLDK
RVETLFPVIEPRLVESIKSDLELTLSDNRKSWEMQPDGTYIRKRGGRPAVDSQRLFMRRSLRRKKNIKKKVKGL
>Mature_713_residues
TDSENGTLVPAAIAEPDLRDPLLYVNRELSWIDFNQRVLEEALDSAAHPLLERVKFLSIFSSNLDEFFMIRVAGLDDQCA
AGINERSVDGLTPIEMLERIRERVIGQLRQRNACFFDDILPALKRKGIEFVSVSSLSVEQQQLLQHYFRKEVFPVLTPLA
FDTGHPFPFMSNLSLNLAIELEDEESGAIKFARVKVPGILSRIIRLDQIEGLGFDDGRIRLLWLEDLVEHNLDQLFPKMR
ILQCHPFRIIRDADIEIEEDEAGDLLESIEQGVRSRRYGKVVRLDINPDMPHSIRSLLVKNLETYERNVYEIGGVLGMSA
LMELLKIDRPDLKDELFVPNNPLDDKRTADIFAEMRSGDMLLHHPYDSFKPVVDLIWQAARDPDVLSIKQTLYRVGSNSP
VVKALMFAAEQRKQVAVLVELKARFDEENNILWARSLEDAGAHVVYGLPGLKTHAKLTMIVRREQEGLRHYLHLGTGNYN
TVTARIYTDYSYLTTDPVLADDVTELFNSLTGYSKHREYRSLIVSPLNMRRWIMEMIRHEVDHQKHTGNGRIVMKMNALV
DEEIIRALYRASMAGVKIDLAIRGICCLKPGIPGISENIRVVSVIGRFLEHSRVYYFNNGDHARIFLGSADIMPRNLDKR
VETLFPVIEPRLVESIKSDLELTLSDNRKSWEMQPDGTYIRKRGGRPAVDSQRLFMRRSLRRKKNIKKKVKGL

Specific function: Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)

COG id: COG0855

COG function: function code P; Polyphosphate kinase

Gene ontology:

Cell location: Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the polyphosphate kinase family

Homologues:

Organism=Escherichia coli, GI1788847, Length=687, Percent_Identity=33.6244541484716, Blast_Score=380, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PPK2_CHLTE (O68984)

Other databases:

- EMBL:   AE006470
- EMBL:   AF060078
- RefSeq:   NP_661940.1
- ProteinModelPortal:   O68984
- SMR:   O68984
- GeneID:   1006966
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT1049
- NMPDR:   fig|194439.1.peg.1034
- TIGR:   CT1049
- HOGENOM:   HBG341268
- OMA:   EITKAPR
- ProtClustDB:   PRK05443
- BioCyc:   CTEP194439:CT_1049-MONOMER
- BRENDA:   2.7.4.1
- HAMAP:   MF_00347
- InterPro:   IPR003414
- PIRSF:   PIRSF015589
- TIGRFAMs:   TIGR03705

Pfam domain/function: PF02503 PP_kinase

EC number: =2.7.4.1

Molecular weight: Translated: 81893; Mature: 81762

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: ACT_SITE 455-455 ACT_SITE 474-474

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSENGTLVPAAIAEPDLRDPLLYVNRELSWIDFNQRVLEEALDSAAHPLLERVKFLSI
CCCCCCCEEEEHHCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
FSSNLDEFFMIRVAGLDDQCAAGINERSVDGLTPIEMLERIRERVIGQLRQRNACFFDDI
HHCCCCEEEEEEEECCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
LPALKRKGIEFVSVSSLSVEQQQLLQHYFRKEVFPVLTPLAFDTGHPFPFMSNLSLNLAI
HHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCEEEEEE
ELEDEESGAIKFARVKVPGILSRIIRLDQIEGLGFDDGRIRLLWLEDLVEHNLDQLFPKM
EEECCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHCCHHHHHHHH
RILQCHPFRIIRDADIEIEEDEAGDLLESIEQGVRSRRYGKVVRLDINPDMPHSIRSLLV
HHEEECCEEEEECCCCEECCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH
KNLETYERNVYEIGGVLGMSALMELLKIDRPDLKDELFVPNNPLDDKRTADIFAEMRSGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHHHHCCCC
MLLHHPYDSFKPVVDLIWQAARDPDVLSIKQTLYRVGSNSPVVKALMFAAEQRKQVAVLV
EEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEEE
ELKARFDEENNILWARSLEDAGAHVVYGLPGLKTHAKLTMIVRREQEGLRHYLHLGTGNY
EEHHHCCCCCCEEEEECCCCCCCEEEECCCCCCCCHHEEHHHHHHHHHHHHHEEECCCCC
NTVTARIYTDYSYLTTDPVLADDVTELFNSLTGYSKHREYRSLIVSPLNMRRWIMEMIRH
CEEEEEEEECCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
EVDHQKHTGNGRIVMKMNALVDEEIIRALYRASMAGVKIDLAIRGICCLKPGIPGISENI
HHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEECCCCCCCCCCH
RVVSVIGRFLEHSRVYYFNNGDHARIFLGSADIMPRNLDKRVETLFPVIEPRLVESIKSD
HHHHHHHHHHHCCEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHCHHHHHHHHHC
LELTLSDNRKSWEMQPDGTYIRKRGGRPAVDSQRLFMRRSLRRKKNIKKKVKGL
EEEEECCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TDSENGTLVPAAIAEPDLRDPLLYVNRELSWIDFNQRVLEEALDSAAHPLLERVKFLSI
CCCCCCEEEEHHCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHH
FSSNLDEFFMIRVAGLDDQCAAGINERSVDGLTPIEMLERIRERVIGQLRQRNACFFDDI
HHCCCCEEEEEEEECCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHH
LPALKRKGIEFVSVSSLSVEQQQLLQHYFRKEVFPVLTPLAFDTGHPFPFMSNLSLNLAI
HHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCEEEEEE
ELEDEESGAIKFARVKVPGILSRIIRLDQIEGLGFDDGRIRLLWLEDLVEHNLDQLFPKM
EEECCCCCCEEEEEEECHHHHHHHHHHHHHCCCCCCCCCEEEEEHHHHHHCCHHHHHHHH
RILQCHPFRIIRDADIEIEEDEAGDLLESIEQGVRSRRYGKVVRLDINPDMPHSIRSLLV
HHEEECCEEEEECCCCEECCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHH
KNLETYERNVYEIGGVLGMSALMELLKIDRPDLKDELFVPNNPLDDKRTADIFAEMRSGD
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCHHHHHHHHHCCCC
MLLHHPYDSFKPVVDLIWQAARDPDVLSIKQTLYRVGSNSPVVKALMFAAEQRKQVAVLV
EEEECCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHEEEEE
ELKARFDEENNILWARSLEDAGAHVVYGLPGLKTHAKLTMIVRREQEGLRHYLHLGTGNY
EEHHHCCCCCCEEEEECCCCCCCEEEECCCCCCCCHHEEHHHHHHHHHHHHHEEECCCCC
NTVTARIYTDYSYLTTDPVLADDVTELFNSLTGYSKHREYRSLIVSPLNMRRWIMEMIRH
CEEEEEEEECCEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHH
EVDHQKHTGNGRIVMKMNALVDEEIIRALYRASMAGVKIDLAIRGICCLKPGIPGISENI
HHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCEEEEEEEEEEEEECCCCCCCCCCH
RVVSVIGRFLEHSRVYYFNNGDHARIFLGSADIMPRNLDKRVETLFPVIEPRLVESIKSD
HHHHHHHHHHHCCEEEEEECCCEEEEEEECCCCCCCCHHHHHHHHHHHHCHHHHHHHHHC
LELTLSDNRKSWEMQPDGTYIRKRGGRPAVDSQRLFMRRSLRRKKNIKKKVKGL
EEEEECCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12093901