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The map label for this gene is ygfA [C]

Identifier: 21673874

GI number: 21673874

Start: 984204

End: 984803

Strand: Direct

Name: ygfA [C]

Synonym: CT1048

Alternate gene names: 21673874

Gene position: 984204-984803 (Clockwise)

Preceding gene: 21673871

Following gene: 21673875

Centisome position: 45.67

GC content: 55.5

Gene sequence:

>600_bases
ATGGAATTTGCAATCGAGAGCAAACCGGAATTGCGGAAGAGGCTGCTTGCGAGGCGCAGGGCGATGACGCTGGAGCGGTG
GCTTTCGGATAGCGAAAAGATTCAGGCGCACGCCGCATCATTGCCGAAGTTGCGCGAGGCCGCTCGGGTTCACTGCTACG
TCTCGATGGAGCACGACCGCGAGGCGCGGACGCTAGAGCTGCTCGAAAAGCTTGCACTCGAAGGGAAAGCGGTGTATATG
CCTTATATTGAACAGGGGATCATGAAGACTTCCATTTACCATTCTGCCCAAAAGTTCAGGATTTCGGTATCGGCACCGCC
CACTCCCGAGCCGCTCGTGCTCTCCGGAGAGGAGCGTTTCGAGGTGGTCTTTGTGCCACTCACGGGTTTTGACCGGAGAG
GGGGGCGGATCGGTTTTGGAAAAGGTTGGTACGACCGTTTCTTCAGCCGTCTGTCTGGGCATGGTATCCATCCGGTGAAA
ATCGGTTTGGCATTCAGTTTTCAGGAGGTTCCGTCGGTGCCGTGTGATCCCTGGGACGAGCCGCTCGACATGGTGGTCAC
AGAAAATGAAATCATCAATTGCCAGTACAACAGCAAATGA

Upstream 100 bases:

>100_bases
TCAGATTTATTATCTTGCGAGTAGATAACGTAACTGAACCGCCTGTCGCGCGCTCCTTTTCGGACGAGGCAGCAGGCAAG
AACGAGAGGATTGCCCCTGC

Downstream 100 bases:

>100_bases
CAGATTCGGAAAACGGGACATTGGTTCCGGCGGCTATAGCCGAGCCGGATCTGCGCGATCCCTTGCTCTACGTGAACCGT
GAGCTGAGCTGGATCGATTT

Product: 5-formyltetrahydrofolate cyclo-ligase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MEFAIESKPELRKRLLARRRAMTLERWLSDSEKIQAHAASLPKLREAARVHCYVSMEHDREARTLELLEKLALEGKAVYM
PYIEQGIMKTSIYHSAQKFRISVSAPPTPEPLVLSGEERFEVVFVPLTGFDRRGGRIGFGKGWYDRFFSRLSGHGIHPVK
IGLAFSFQEVPSVPCDPWDEPLDMVVTENEIINCQYNSK

Sequences:

>Translated_199_residues
MEFAIESKPELRKRLLARRRAMTLERWLSDSEKIQAHAASLPKLREAARVHCYVSMEHDREARTLELLEKLALEGKAVYM
PYIEQGIMKTSIYHSAQKFRISVSAPPTPEPLVLSGEERFEVVFVPLTGFDRRGGRIGFGKGWYDRFFSRLSGHGIHPVK
IGLAFSFQEVPSVPCDPWDEPLDMVVTENEIINCQYNSK
>Mature_199_residues
MEFAIESKPELRKRLLARRRAMTLERWLSDSEKIQAHAASLPKLREAARVHCYVSMEHDREARTLELLEKLALEGKAVYM
PYIEQGIMKTSIYHSAQKFRISVSAPPTPEPLVLSGEERFEVVFVPLTGFDRRGGRIGFGKGWYDRFFSRLSGHGIHPVK
IGLAFSFQEVPSVPCDPWDEPLDMVVTENEIINCQYNSK

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=204, Percent_Identity=25.9803921568627, Blast_Score=67, Evalue=8e-12,
Organism=Escherichia coli, GI1789278, Length=180, Percent_Identity=31.1111111111111, Blast_Score=72, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 22809; Mature: 22809

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFAIESKPELRKRLLARRRAMTLERWLSDSEKIQAHAASLPKLREAARVHCYVSMEHDR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHEEEEEEEECCCC
EARTLELLEKLALEGKAVYMPYIEQGIMKTSIYHSAQKFRISVSAPPTPEPLVLSGEERF
CHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEECCCCE
EVVFVPLTGFDRRGGRIGFGKGWYDRFFSRLSGHGIHPVKIGLAFSFQEVPSVPCDPWDE
EEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEEHHHCCCCCCCCCCC
PLDMVVTENEIINCQYNSK
CCCEEEECCEEEEEEECCC
>Mature Secondary Structure
MEFAIESKPELRKRLLARRRAMTLERWLSDSEKIQAHAASLPKLREAARVHCYVSMEHDR
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCHHHHHHHEEEEEEEECCCC
EARTLELLEKLALEGKAVYMPYIEQGIMKTSIYHSAQKFRISVSAPPTPEPLVLSGEERF
CHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHCCEEEEEEECCCCCCCCEEEECCCCE
EVVFVPLTGFDRRGGRIGFGKGWYDRFFSRLSGHGIHPVKIGLAFSFQEVPSVPCDPWDE
EEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCEEEEEEEEEHHHCCCCCCCCCCC
PLDMVVTENEIINCQYNSK
CCCEEEECCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]