Click here to switch to the map view.

The map label for this gene is yfnA [H]

Identifier: 21673751

GI number: 21673751

Start: 873183

End: 874670

Strand: Direct

Name: yfnA [H]

Synonym: CT0923

Alternate gene names: 21673751

Gene position: 873183-874670 (Clockwise)

Preceding gene: 21673750

Following gene: 21673752

Centisome position: 40.52

GC content: 57.12

Gene sequence:

>1488_bases
GTGAAAAACAGCTTCAGAAAAAAGCCGCTTTCGTTGCTGCTCGAAGAGATGAAGAGCGAGCACCGGCTCAACCGTGTTCT
CGGCCCGTTGGCGCTGACCAGCCTTGGGGTTGGCGCGATCATTGGTACCGGCATTTTCGTGCTCATCGGTGTAGCCGCGC
ATGACAAGGCAGGTCCCGCTGTAACGCTCTCCTTTGCTCTTGCCGGGCTGGCCTGCGTTTTTGCGGCGCTCTGTTACGCC
GAATTCGCCTCGATGGCCCCGGTTGCCGGTTCTGCTTATACCTATGCCTACGCCACACTTGGTGAACTTTTCGCCTGGAT
CATCGGCTGGGATCTCATTCTCGAATACGCCGTTGCATCGGCCACCGTGGCGCACGGATGGTCACACTACTTTCAGGATT
TCATGGGCATATTTGGCCTGCACATACCGGAAATCTTTTCGCGAGCGCCTCTCGACTTCGATCCGGCAACCGGCTCGCTG
GTGCTGACCGGCTCGATGTTCGACCTTCCGGCGGTCATCATCGTGCTCATTGTGACGGTGATTCTGGTCAAGGGGATTCG
TGAAAGCGCCGGGTTCAACACGGCGATGGTCATCGTCAAGGTAGCTATCGTGCTGCTGGTCATTGTTCTTGGTGCGCAGT
ATGTCAAGCCCGAAAACTGGCAGCCTTTTGCGCCGTTCGGTTATTCAGGACTGAGCGTGTTTGGTCATACCATTCTTGGC
GAAACCGGAGCGGGTGGTGCGCCTGTCGGCGTGCTGGCGGGTGCGGCCATGATTTTCTTTGCCTACATCGGTTTCGATTC
GATCTCGACCCATGCCGAAGAGGCGCGCCGGCCCGAGCGTGATGTGCCGATCGGTATTATCGCCTCGCTCATCATCTGCA
CGATGCTCTATGTTGCGGTTGCTGCAGTGATTACCGGCATGGTGCCTTACGATCAGATCAACATTGATGCGCCAGTCTCC
TACGCATTCAAGCAGGTCGGCCTCGACTGGGCGCAGTTTCTCGTCTCCCTCGGAGCCATCACAGGCATCACCTCGGTGCT
GCTTGTCATGATGCTCAGTCAGCCGAGAATCTTTCTGGCTATGGCTCGCGATGGTCTTTTGCCGAATAAGTTTTTCGGCG
TGGTTCACCCGAAGTTCAAAACGCCCTGGAATGCGACCATTCTCACCGGCATTTTTGTGGCCATTCTCGGCGCGTTCCTG
CCGCTTCGCTTGCTGGCCGAGCTGGTCAACATCGGTACACTCTTCGCTTTCGTCGTGGTCTGCGCGGCGGTACTCATCAT
GCGCCGTACCAATCCCGATGCTGAACGCCCATTCAGAGCGCCGCTGGTGCCTTTCGTGCCCATTGCCGGCATTCTGACCT
GCCTTCTGCTCATGTTCTCGCTGCCTGCCGAGAACTGGTGGCGGCTCATCGTCTGGCTGTTGATAGGTTTCTGCATCTAC
TTCTTCTACGGACGCCACCACAGCGTTCTGAACCAGCATCACGACTGA

Upstream 100 bases:

>100_bases
TGAGGGAAAAGCTGGAAAAATCTCTGTATATTCAAAAGTTTTTACCTTTTCCGCTTTGCCCTTCTGGGTGCTTTTCTTTG
AACCAAAAGCACATTTGCCC

Downstream 100 bases:

>100_bases
ACATTCAGGTGGTTATCAGGAACGTTTCCATTATTTGGAAGCCTCCTGAACCGGCTGTCTGGATGGGTTGTCAAACGTAT
GCATGTTTTTTACCGCCTTT

Product: amino acid permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 495; Mature: 495

Protein sequence:

>495_residues
MKNSFRKKPLSLLLEEMKSEHRLNRVLGPLALTSLGVGAIIGTGIFVLIGVAAHDKAGPAVTLSFALAGLACVFAALCYA
EFASMAPVAGSAYTYAYATLGELFAWIIGWDLILEYAVASATVAHGWSHYFQDFMGIFGLHIPEIFSRAPLDFDPATGSL
VLTGSMFDLPAVIIVLIVTVILVKGIRESAGFNTAMVIVKVAIVLLVIVLGAQYVKPENWQPFAPFGYSGLSVFGHTILG
ETGAGGAPVGVLAGAAMIFFAYIGFDSISTHAEEARRPERDVPIGIIASLIICTMLYVAVAAVITGMVPYDQINIDAPVS
YAFKQVGLDWAQFLVSLGAITGITSVLLVMMLSQPRIFLAMARDGLLPNKFFGVVHPKFKTPWNATILTGIFVAILGAFL
PLRLLAELVNIGTLFAFVVVCAAVLIMRRTNPDAERPFRAPLVPFVPIAGILTCLLLMFSLPAENWWRLIVWLLIGFCIY
FFYGRHHSVLNQHHD

Sequences:

>Translated_495_residues
MKNSFRKKPLSLLLEEMKSEHRLNRVLGPLALTSLGVGAIIGTGIFVLIGVAAHDKAGPAVTLSFALAGLACVFAALCYA
EFASMAPVAGSAYTYAYATLGELFAWIIGWDLILEYAVASATVAHGWSHYFQDFMGIFGLHIPEIFSRAPLDFDPATGSL
VLTGSMFDLPAVIIVLIVTVILVKGIRESAGFNTAMVIVKVAIVLLVIVLGAQYVKPENWQPFAPFGYSGLSVFGHTILG
ETGAGGAPVGVLAGAAMIFFAYIGFDSISTHAEEARRPERDVPIGIIASLIICTMLYVAVAAVITGMVPYDQINIDAPVS
YAFKQVGLDWAQFLVSLGAITGITSVLLVMMLSQPRIFLAMARDGLLPNKFFGVVHPKFKTPWNATILTGIFVAILGAFL
PLRLLAELVNIGTLFAFVVVCAAVLIMRRTNPDAERPFRAPLVPFVPIAGILTCLLLMFSLPAENWWRLIVWLLIGFCIY
FFYGRHHSVLNQHHD
>Mature_495_residues
MKNSFRKKPLSLLLEEMKSEHRLNRVLGPLALTSLGVGAIIGTGIFVLIGVAAHDKAGPAVTLSFALAGLACVFAALCYA
EFASMAPVAGSAYTYAYATLGELFAWIIGWDLILEYAVASATVAHGWSHYFQDFMGIFGLHIPEIFSRAPLDFDPATGSL
VLTGSMFDLPAVIIVLIVTVILVKGIRESAGFNTAMVIVKVAIVLLVIVLGAQYVKPENWQPFAPFGYSGLSVFGHTILG
ETGAGGAPVGVLAGAAMIFFAYIGFDSISTHAEEARRPERDVPIGIIASLIICTMLYVAVAAVITGMVPYDQINIDAPVS
YAFKQVGLDWAQFLVSLGAITGITSVLLVMMLSQPRIFLAMARDGLLPNKFFGVVHPKFKTPWNATILTGIFVAILGAFL
PLRLLAELVNIGTLFAFVVVCAAVLIMRRTNPDAERPFRAPLVPFVPIAGILTCLLLMFSLPAENWWRLIVWLLIGFCIY
FFYGRHHSVLNQHHD

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI4507047, Length=434, Percent_Identity=39.1705069124424, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI114326544, Length=436, Percent_Identity=36.697247706422, Blast_Score=251, Evalue=9e-67,
Organism=Homo sapiens, GI114326550, Length=436, Percent_Identity=36.697247706422, Blast_Score=251, Evalue=9e-67,
Organism=Homo sapiens, GI258645169, Length=434, Percent_Identity=36.8663594470046, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI258614003, Length=434, Percent_Identity=36.405529953917, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI258614005, Length=434, Percent_Identity=36.405529953917, Blast_Score=246, Evalue=2e-65,
Organism=Homo sapiens, GI181337167, Length=441, Percent_Identity=36.5079365079365, Blast_Score=245, Evalue=8e-65,
Organism=Homo sapiens, GI110347453, Length=430, Percent_Identity=37.2093023255814, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI186910308, Length=455, Percent_Identity=25.4945054945055, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI186910306, Length=455, Percent_Identity=25.4945054945055, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI186910304, Length=455, Percent_Identity=25.4945054945055, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI33286428, Length=449, Percent_Identity=26.2806236080178, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI7657683, Length=401, Percent_Identity=21.9451371571072, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI71979932, Length=242, Percent_Identity=27.2727272727273, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082250, Length=492, Percent_Identity=26.219512195122, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI87081869, Length=496, Percent_Identity=25.2016129032258, Blast_Score=99, Evalue=4e-22,
Organism=Escherichia coli, GI87082023, Length=469, Percent_Identity=25.3731343283582, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI87081708, Length=484, Percent_Identity=22.5206611570248, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87081915, Length=443, Percent_Identity=23.7020316027088, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786602, Length=431, Percent_Identity=23.6658932714617, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788480, Length=489, Percent_Identity=22.2903885480573, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1789017, Length=474, Percent_Identity=24.0506329113924, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI2367353, Length=437, Percent_Identity=24.2562929061785, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI48994972, Length=460, Percent_Identity=23.2608695652174, Blast_Score=65, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=410, Percent_Identity=37.3170731707317, Blast_Score=256, Evalue=3e-68,
Organism=Caenorhabditis elegans, GI17531343, Length=427, Percent_Identity=34.6604215456674, Blast_Score=229, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17533459, Length=431, Percent_Identity=35.2668213457077, Blast_Score=227, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17540018, Length=430, Percent_Identity=26.046511627907, Blast_Score=88, Evalue=9e-18,
Organism=Caenorhabditis elegans, GI17537453, Length=403, Percent_Identity=21.5880893300248, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17568033, Length=447, Percent_Identity=23.489932885906, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI221512776, Length=443, Percent_Identity=36.7945823927765, Blast_Score=277, Evalue=1e-74,
Organism=Drosophila melanogaster, GI24666159, Length=443, Percent_Identity=36.7945823927765, Blast_Score=276, Evalue=2e-74,
Organism=Drosophila melanogaster, GI24667468, Length=443, Percent_Identity=35.4401805869075, Blast_Score=266, Evalue=2e-71,
Organism=Drosophila melanogaster, GI24668806, Length=434, Percent_Identity=37.3271889400922, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI21356285, Length=434, Percent_Identity=37.3271889400922, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI24668802, Length=434, Percent_Identity=37.3271889400922, Blast_Score=264, Evalue=1e-70,
Organism=Drosophila melanogaster, GI281366235, Length=443, Percent_Identity=36.7945823927765, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI116007820, Length=443, Percent_Identity=36.7945823927765, Blast_Score=238, Evalue=9e-63,
Organism=Drosophila melanogaster, GI116007818, Length=424, Percent_Identity=37.2641509433962, Blast_Score=234, Evalue=7e-62,
Organism=Drosophila melanogaster, GI85725152, Length=424, Percent_Identity=37.2641509433962, Blast_Score=234, Evalue=7e-62,
Organism=Drosophila melanogaster, GI161077963, Length=453, Percent_Identity=32.8918322295806, Blast_Score=212, Evalue=4e-55,
Organism=Drosophila melanogaster, GI21357367, Length=455, Percent_Identity=24.3956043956044, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53508; Mature: 53508

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCHHHHHHCCCC
>Mature Secondary Structure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HHHCCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]