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The map label for this gene is yloB [H]

Identifier: 21673750

GI number: 21673750

Start: 872396

End: 873085

Strand: Direct

Name: yloB [H]

Synonym: CT0922

Alternate gene names: 21673750

Gene position: 872396-873085 (Clockwise)

Preceding gene: 21673748

Following gene: 21673751

Centisome position: 40.48

GC content: 57.97

Gene sequence:

>690_bases
GTGCTATTTGCGGCAGCAATTTCCGAGAATCGACGAGCAGTCATTCTCCTCCGAAACGAAGCGGTTGGAAGCGTCGAGGT
GTTCGCGCGGGTTTCTCTGGAGTCCAACATTGGCGAACTCGGCCTCATGGCCGGAGCGACGCTGCTGGGTATTCCGCTGC
TGCTCACGGCGGTGCAGATTCTCTATGTGAACCTCGCCACCGATGGTCTTCCGGCACTTGCCCTCGCCGTCGACCCCGCC
GAACCGGGCATTATGAACCGTCCGCCGAACGAGCGGAAGCAGGGTATCTTTACCCGTCCGATCATGGCCCTGATGCTTGC
CGGCGGACTCTGGTCTGCGCTGGTCAACCTGGTGCTTTTCGAGTGGGCGCGCCACTCCGGGCGTTCTCTTTCGGAGGCGA
TGACCATGACCTTCGTCTCCCTTGTGCTCATCCAGTTTTTCAAGGCGTATAACTTCCGTTCGGAGCGGGAGCACGTTTTC
AAAAACACCTTTACGAACCGCTGGTTGAACCTCGCAATCATCTGGGAGCTGGTCATGCTCGCGGCGATTATCTACGTGCC
TGTGCTGACGGTGCCCTTTGGTACCTTTGCGATGCCACCGCATGACTGGCTGATCGTGATATGCGGAGCGCTGACCATCG
TGCCGGTCATTGAAGGGGTTAAATGGCTGATCAGAAGTGGCAGAGTTTGA

Upstream 100 bases:

>100_bases
GACGCGGCGATCGGCAAGTCGCCGGAGGGGGAGTGGACGATTTCCGGTGATCCTACCGAGGGGCCCTCGTCGTCTCGGTG
CGGAAGGCGGGATTCGACGA

Downstream 100 bases:

>100_bases
GGGAAAAGCTGGAAAAATCTCTGTATATTCAAAAGTTTTTACCTTTTCCGCTTTGCCCTTCTGGGTGCTTTTCTTTGAAC
CAAAAGCACATTTGCCCGTG

Product: cation transporter E1-E2 family ATPase

Products: NA

Alternate protein names: Calcium pump [H]

Number of amino acids: Translated: 229; Mature: 229

Protein sequence:

>229_residues
MLFAAAISENRRAVILLRNEAVGSVEVFARVSLESNIGELGLMAGATLLGIPLLLTAVQILYVNLATDGLPALALAVDPA
EPGIMNRPPNERKQGIFTRPIMALMLAGGLWSALVNLVLFEWARHSGRSLSEAMTMTFVSLVLIQFFKAYNFRSEREHVF
KNTFTNRWLNLAIIWELVMLAAIIYVPVLTVPFGTFAMPPHDWLIVICGALTIVPVIEGVKWLIRSGRV

Sequences:

>Translated_229_residues
MLFAAAISENRRAVILLRNEAVGSVEVFARVSLESNIGELGLMAGATLLGIPLLLTAVQILYVNLATDGLPALALAVDPA
EPGIMNRPPNERKQGIFTRPIMALMLAGGLWSALVNLVLFEWARHSGRSLSEAMTMTFVSLVLIQFFKAYNFRSEREHVF
KNTFTNRWLNLAIIWELVMLAAIIYVPVLTVPFGTFAMPPHDWLIVICGALTIVPVIEGVKWLIRSGRV
>Mature_229_residues
MLFAAAISENRRAVILLRNEAVGSVEVFARVSLESNIGELGLMAGATLLGIPLLLTAVQILYVNLATDGLPALALAVDPA
EPGIMNRPPNERKQGIFTRPIMALMLAGGLWSALVNLVLFEWARHSGRSLSEAMTMTFVSLVLIQFFKAYNFRSEREHVF
KNTFTNRWLNLAIIWELVMLAAIIYVPVLTVPFGTFAMPPHDWLIVICGALTIVPVIEGVKWLIRSGRV

Specific function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium [H]

COG id: COG0474

COG function: function code P; Cation transport ATPase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIA subfamily [H]

Homologues:

Organism=Homo sapiens, GI48762685, Length=173, Percent_Identity=29.4797687861272, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI48762691, Length=173, Percent_Identity=29.4797687861272, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI48762689, Length=173, Percent_Identity=29.4797687861272, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI48762687, Length=173, Percent_Identity=29.4797687861272, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI118498343, Length=185, Percent_Identity=25.9459459459459, Blast_Score=67, Evalue=9e-12,
Organism=Homo sapiens, GI24638454, Length=235, Percent_Identity=26.8085106382979, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI209413709, Length=235, Percent_Identity=26.8085106382979, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI4502285, Length=235, Percent_Identity=26.8085106382979, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71997275, Length=181, Percent_Identity=28.7292817679558, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71997262, Length=181, Percent_Identity=28.7292817679558, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6321271, Length=175, Percent_Identity=30.2857142857143, Blast_Score=85, Evalue=1e-17,
Organism=Drosophila melanogaster, GI161085803, Length=225, Percent_Identity=30.2222222222222, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24668696, Length=225, Percent_Identity=30.2222222222222, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24668708, Length=225, Percent_Identity=30.2222222222222, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24668704, Length=225, Percent_Identity=30.2222222222222, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI281366617, Length=225, Percent_Identity=30.2222222222222, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI17136664, Length=230, Percent_Identity=26.9565217391304, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24762455, Length=235, Percent_Identity=26.3829787234043, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24762453, Length=235, Percent_Identity=26.3829787234043, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24762447, Length=235, Percent_Identity=26.3829787234043, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24762457, Length=235, Percent_Identity=26.3829787234043, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24762449, Length=235, Percent_Identity=26.3829787234043, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24762445, Length=235, Percent_Identity=26.3829787234043, Blast_Score=71, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24762451, Length=235, Percent_Identity=26.3829787234043, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008250
- InterPro:   IPR006068
- InterPro:   IPR004014
- InterPro:   IPR000695
- InterPro:   IPR001757
- InterPro:   IPR018303
- InterPro:   IPR005834
- InterPro:   IPR023214 [H]

Pfam domain/function: PF00689 Cation_ATPase_C; PF00690 Cation_ATPase_N; PF00122 E1-E2_ATPase; PF00702 Hydrolase [H]

EC number: =3.6.3.8 [H]

Molecular weight: Translated: 25269; Mature: 25269

Theoretical pI: Translated: 9.16; Mature: 9.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFAAAISENRRAVILLRNEAVGSVEVFARVSLESNIGELGLMAGATLLGIPLLLTAVQI
CEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LYVNLATDGLPALALAVDPAEPGIMNRPPNERKQGIFTRPIMALMLAGGLWSALVNLVLF
HHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
EWARHSGRSLSEAMTMTFVSLVLIQFFKAYNFRSEREHVFKNTFTNRWLNLAIIWELVML
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAIIYVPVLTVPFGTFAMPPHDWLIVICGALTIVPVIEGVKWLIRSGRV
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLFAAAISENRRAVILLRNEAVGSVEVFARVSLESNIGELGLMAGATLLGIPLLLTAVQI
CEEEEEECCCCCEEEEEECCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
LYVNLATDGLPALALAVDPAEPGIMNRPPNERKQGIFTRPIMALMLAGGLWSALVNLVLF
HHHHHCCCCCCEEEEEECCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
EWARHSGRSLSEAMTMTFVSLVLIQFFKAYNFRSEREHVFKNTFTNRWLNLAIIWELVML
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAIIYVPVLTVPFGTFAMPPHDWLIVICGALTIVPVIEGVKWLIRSGRV
HHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]