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The map label for this gene is inlA [H]

Identifier: 21673665

GI number: 21673665

Start: 797371

End: 798579

Strand: Reverse

Name: inlA [H]

Synonym: CT0836

Alternate gene names: 21673665

Gene position: 798579-797371 (Counterclockwise)

Preceding gene: 21673666

Following gene: 21673660

Centisome position: 37.06

GC content: 57.32

Gene sequence:

>1209_bases
TTGGAGCAGAATATCTACAAGCAGTGTCCGGTCTGCGGCTTTCCGCTGACCCGGCAGAATGCGATCTGTCCGAGATGCGG
CAACGACATTCTCGAAGACATCAATACGCTCGACGAACAGAATCACGAAAAGCACTACCGGATCATCGAGGAGAAAAAGG
CCGACTGGTATATCCGGTGCCTGGCCGAAAACCTCGACACAGGCAAATCGCCGCTCGTGAACTTCCCGAACGACTACACC
GGACCGATGCACTCGGGCTTCCACAGTCGCCTGACCGCCGCCGAACAGGAGGCGCTTGCCACATCGCGAGCCGTGCTCTT
GCGAGACCCGCAGAAGCGGCACAACTGGTTCAAGGCGCTGGGCAACGACTGGAAGGAGGTGGTCAAAAACACCCTGAAAA
TCCAGCGCGATCCCTCGGACGAAGAACTGCTTGATTTTCTGAACGCCACCAGCCTCCGATGCAACAACATGCGAATCCAC
AACCTCGCGCCGGTCAGCCTGCTCGAAAACCTGGAACAGCTCCGGTGCGACGAAACGCCGGTCGAAAGCCTCGAACCGCT
GCGGAACCTCCGCAACCTCAGACGCCTGTATGCCTTCGACTGCGACTTCACCTCCCTCGACCCGCTGCGCGATATTCTGT
CTCTCAAGCTGCTCTGGGTATCGAGTACCGAAATCAGCGACCTCGAACCGCTCAGCGCTCTGGTCAATCTGGAGGAGCTG
TACTGCTCCGAGACGATGGTGAGCGACCTGACGCCGGTCAGCGGGCTTTTCAGACTCGAAAAGCTGAGCTGTTACAAAAC
GGAGATTACCTCGATCGAAGCGCTCCGAAATCTGACCAATCTCTCCGAACTCGGCATCAACAGCACCGGCGTCAGTTCAC
TCGAACCGCTGGCCCGGCTCGAAAATCTCGAATATCTCCGTTGCAGCCGCACGGCCATCACCAGCCTCGAACCGCTGAGA
AATCTGGTGGCGCTCAAGGAGCTGAGCATCGAACAGACCGCCATCCACACCCTCGAACCCTTGTCGGGACTTGTGGAGCT
GGAAGAGCTTTTCATCACCGGCACGCTTGTTGACTCGATAGCGCCGCTGATGAACCTGATGAGCCTCGAAAAACTGGAGC
TGTCGGCAGGAAGGATTCCCCAATCCGAAATCGACCACTTCATGCAACTGAACCCGGCCTGCGAGGTGATCCTTAAATCG
AATGGATGA

Upstream 100 bases:

>100_bases
CGAAAAACCGACACGGGCCGCCGGATGTGGTTTGAGGTGTTTTTTTCTTATTTTGCGCAAAGATAGCACAGGCTAACCCA
ACCTTCAAGGCCATACCTAA

Downstream 100 bases:

>100_bases
CGGATTGGGCTGAAGGGACTGTCAGAGAATGAGAAAGGGGAAGAGTTTCCGAAATGGAGTCTCTTCCTTTTTTTGCTTGT
TTGGAGCCGTCAAAGTGATG

Product: internalin-related protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 402

Protein sequence:

>402_residues
MEQNIYKQCPVCGFPLTRQNAICPRCGNDILEDINTLDEQNHEKHYRIIEEKKADWYIRCLAENLDTGKSPLVNFPNDYT
GPMHSGFHSRLTAAEQEALATSRAVLLRDPQKRHNWFKALGNDWKEVVKNTLKIQRDPSDEELLDFLNATSLRCNNMRIH
NLAPVSLLENLEQLRCDETPVESLEPLRNLRNLRRLYAFDCDFTSLDPLRDILSLKLLWVSSTEISDLEPLSALVNLEEL
YCSETMVSDLTPVSGLFRLEKLSCYKTEITSIEALRNLTNLSELGINSTGVSSLEPLARLENLEYLRCSRTAITSLEPLR
NLVALKELSIEQTAIHTLEPLSGLVELEELFITGTLVDSIAPLMNLMSLEKLELSAGRIPQSEIDHFMQLNPACEVILKS
NG

Sequences:

>Translated_402_residues
MEQNIYKQCPVCGFPLTRQNAICPRCGNDILEDINTLDEQNHEKHYRIIEEKKADWYIRCLAENLDTGKSPLVNFPNDYT
GPMHSGFHSRLTAAEQEALATSRAVLLRDPQKRHNWFKALGNDWKEVVKNTLKIQRDPSDEELLDFLNATSLRCNNMRIH
NLAPVSLLENLEQLRCDETPVESLEPLRNLRNLRRLYAFDCDFTSLDPLRDILSLKLLWVSSTEISDLEPLSALVNLEEL
YCSETMVSDLTPVSGLFRLEKLSCYKTEITSIEALRNLTNLSELGINSTGVSSLEPLARLENLEYLRCSRTAITSLEPLR
NLVALKELSIEQTAIHTLEPLSGLVELEELFITGTLVDSIAPLMNLMSLEKLELSAGRIPQSEIDHFMQLNPACEVILKS
NG
>Mature_402_residues
MEQNIYKQCPVCGFPLTRQNAICPRCGNDILEDINTLDEQNHEKHYRIIEEKKADWYIRCLAENLDTGKSPLVNFPNDYT
GPMHSGFHSRLTAAEQEALATSRAVLLRDPQKRHNWFKALGNDWKEVVKNTLKIQRDPSDEELLDFLNATSLRCNNMRIH
NLAPVSLLENLEQLRCDETPVESLEPLRNLRNLRRLYAFDCDFTSLDPLRDILSLKLLWVSSTEISDLEPLSALVNLEEL
YCSETMVSDLTPVSGLFRLEKLSCYKTEITSIEALRNLTNLSELGINSTGVSSLEPLARLENLEYLRCSRTAITSLEPLR
NLVALKELSIEQTAIHTLEPLSGLVELEELFITGTLVDSIAPLMNLMSLEKLELSAGRIPQSEIDHFMQLNPACEVILKS
NG

Specific function: Mediates the entry of Listeria monocytogenes into cells [H]

COG id: COG4886

COG function: function code S; Leucine-rich repeat (LRR) protein

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 14 LRR (leucine-rich) repeats [H]

Homologues:

Organism=Homo sapiens, GI4506013, Length=242, Percent_Identity=25.6198347107438, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17536161, Length=226, Percent_Identity=28.3185840707965, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21358617, Length=210, Percent_Identity=28.0952380952381, Blast_Score=75, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014755
- InterPro:   IPR019948
- InterPro:   IPR014756
- InterPro:   IPR001611
- InterPro:   IPR013378
- InterPro:   IPR019931
- InterPro:   IPR012569
- InterPro:   IPR001899 [H]

Pfam domain/function: PF09479 Flg_new; PF00746 Gram_pos_anchor; PF00560 LRR_1; PF08191 LRR_adjacent [H]

EC number: NA

Molecular weight: Translated: 45609; Mature: 45609

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQNIYKQCPVCGFPLTRQNAICPRCGNDILEDINTLDEQNHEKHYRIIEEKKADWYIRC
CCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHH
LAENLDTGKSPLVNFPNDYTGPMHSGFHSRLTAAEQEALATSRAVLLRDPQKRHNWFKAL
HHHHCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GNDWKEVVKNTLKIQRDPSDEELLDFLNATSLRCNNMRIHNLAPVSLLENLEQLRCDETP
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEECCEEECCCCHHHHHHHHHHHCCCCCC
VESLEPLRNLRNLRRLYAFDCDFTSLDPLRDILSLKLLWVSSTEISDLEPLSALVNLEEL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHH
YCSETMVSDLTPVSGLFRLEKLSCYKTEITSIEALRNLTNLSELGINSTGVSSLEPLARL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
ENLEYLRCSRTAITSLEPLRNLVALKELSIEQTAIHTLEPLSGLVELEELFITGTLVDSI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APLMNLMSLEKLELSAGRIPQSEIDHFMQLNPACEVILKSNG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHEEEECCCC
>Mature Secondary Structure
MEQNIYKQCPVCGFPLTRQNAICPRCGNDILEDINTLDEQNHEKHYRIIEEKKADWYIRC
CCCCHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHCCCHHHHHH
LAENLDTGKSPLVNFPNDYTGPMHSGFHSRLTAAEQEALATSRAVLLRDPQKRHNWFKAL
HHHHCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
GNDWKEVVKNTLKIQRDPSDEELLDFLNATSLRCNNMRIHNLAPVSLLENLEQLRCDETP
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEECCEEECCCCHHHHHHHHHHHCCCCCC
VESLEPLRNLRNLRRLYAFDCDFTSLDPLRDILSLKLLWVSSTEISDLEPLSALVNLEEL
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHH
YCSETMVSDLTPVSGLFRLEKLSCYKTEITSIEALRNLTNLSELGINSTGVSSLEPLARL
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
ENLEYLRCSRTAITSLEPLRNLVALKELSIEQTAIHTLEPLSGLVELEELFITGTLVDSI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
APLMNLMSLEKLELSAGRIPQSEIDHFMQLNPACEVILKSNG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9541569 [H]