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The map label for this gene is htpG

Identifier: 21673658

GI number: 21673658

Start: 788404

End: 790293

Strand: Direct

Name: htpG

Synonym: CT0829

Alternate gene names: 21673658

Gene position: 788404-790293 (Clockwise)

Preceding gene: 21673657

Following gene: 21673659

Centisome position: 36.59

GC content: 57.83

Gene sequence:

>1890_bases
ATGAGCAGCAACCCTACCTCATCCGTTCGTGAGTTTGAATACAAGGCTGAAATGAAACAGCTTCTGAATCTGATCGTCCA
TTCGCTGTACACCCATCCTGAAATTTTTCTTCGTGAGCTGATCTCCAACGCCTCCGATGCGCTCGGCAAGGCGCGTTTTC
GGATGCTTTCGTCTGACGAGGGGCTTGACAAGTCCGGCGATCTGAAGATCACCATCACCGTCGATAAAGAGTCTGGCAGC
TTTGTCATCGAAGACACCGGCATCGGCATGAGCGAGGAGGAGTTGATCTCGAACCTCGGTACGGTGGCCAGCTCCGGCAC
GCTCGGCTTCATGGAGGCGCTGAAGGAGCAGCAGAAAGAGGGACAGCGGCTCGACGCCAACCTCATCGGCCAGTTCGGCG
TAGGCTTCTACTCAGTCTTCATGGTGACCGATGAAGTGACCGTCGAGACCAAAAGCATCGAGAGCGGCTTGCAGGGGTGG
CGGTGGAAATCATCCGGCCAGGGTTCCTACACCATTGAGCCGGTCGAACGCGAAGCTCGCGGCACCCGCATTTCATTCAT
CCTCAAGGAGGAGTTCAGGGAGTTCGCCCAAGAGTACCGCGTCGAGCAGATTATCAAGAAGTACTCAAACTTCGTTGAAT
ATCCGATCTACATCGGCAGCCGCCAGATCAACAGCATGACCGCGCTCTGGCAGCGTCCCAAGAGCGAGCTGAAACAGGAA
GAGGTCAACGAGTTCTACAAGTTCATCGCCAACGATTTCAAGGACCCGCTCGACTACCTGCACGTGTCGGTCGAGGGCGC
GGTGAGCTTCAAGGCGCTGCTTTTCATTCCTTCCGAAGCGCCGATGGAGCTGCTCTACAACCAGGGGGCGCTCGAAAAAC
GCGGGCCGCAGCTCTACGTCAAGAAGGTGCTCATCCAGCACGAGTGCCGCGATCTTCTGCCCGAATATCTGCGCTTCGTG
AGCGGCGTGGTCGATACCGAGGATTTGCCGCTGAACGTTTCGCGCGAGCTGGTGCAGGCAAGCCCGGTGATGGCGAAAAT
CAAGCAGATTCTCACCACCAAGCTGCTCGGCTGGTTCGACACCATCGCCAAAGAGGAGCCGGAGAAGTTCCGCGCCTTCT
ACAAGGCGTTCGGCACGATCCTGAAAATCGGCCTCAACACCGACTTCACCAATCGCGACAAGCTGATCGATCTCTTGCGC
TTCGAGACCACCAAGACCGTCGAGGGCGAGTACGTCACCCTCAAAGAGTACGTCGGGCGCATGGCCGAGGGGCAGACCGA
AATCTACTACCACTCCGGCAGCAGCCGCGCACAGATGCTCGCGCATCCAAACCTCGAATATTTCAGGAAGCGCGACATCG
AGGTGCTTCTGCTCTCCGATCCGGTCGATGTGTTTGTGATTCCCTCGATTTTCGAGTACGACAAGAAGCCGCTCAAGTCG
ATTGAGAAGGCTGAAATTGACATGAGCACGGTCGAGCCCGAAGGTGAGCGGCTCAGTGCTGAGGGCACGGTTGGCGTGAT
TTCGCTCTTCAAGGAAGTGCTCGGCGAGCGCGTGGCCGACGTGGTCGAGTCCAGGCGCCTCGTCAGTTCGCCGGTGACGC
TGGTGAGCGGCAAAGATGCGCTCGACAGCCAGTTCGAGAAGATGATGAAGATGATGAACAAGGATGCCGACATGCCTTCC
ACGAAGAAGATTCTCGAGATCAACACCGCGCATCCGATCATCCGCAACCTGGCGGGCAAGCACGCCGTCGGCCTCTCCAC
CGATCCGGTCGTTCGTGCGGCGGTCACGCAGCTTTTCGAGAGCGCCCTGTTGCTCGAAGGCGACCTCGAATCGGTCGCGG
ACTACGTTTCGCGCATGAACGAACTGGTCGAGGCCGCGACGCGCTCGTAA

Upstream 100 bases:

>100_bases
CTCTCGATTGGCTGATTGCGGAACGCGCTCTCGGCATCTCTCGATTCTCTTCTTTGAAAGAGATCGTTTATCCCGGTTAA
TGTTATCCAGTAGATTTATT

Downstream 100 bases:

>100_bases
CTCGCGGATCGAACAGCACTGCTGTTCGGCGTTATCAAACGGCCTGTCGGGATGCGTGGTTGCTCCGGGCGGGCCGTTTG
ACCGGTAACCCATTAACCAC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 629; Mature: 628

Protein sequence:

>629_residues
MSSNPTSSVREFEYKAEMKQLLNLIVHSLYTHPEIFLRELISNASDALGKARFRMLSSDEGLDKSGDLKITITVDKESGS
FVIEDTGIGMSEEELISNLGTVASSGTLGFMEALKEQQKEGQRLDANLIGQFGVGFYSVFMVTDEVTVETKSIESGLQGW
RWKSSGQGSYTIEPVEREARGTRISFILKEEFREFAQEYRVEQIIKKYSNFVEYPIYIGSRQINSMTALWQRPKSELKQE
EVNEFYKFIANDFKDPLDYLHVSVEGAVSFKALLFIPSEAPMELLYNQGALEKRGPQLYVKKVLIQHECRDLLPEYLRFV
SGVVDTEDLPLNVSRELVQASPVMAKIKQILTTKLLGWFDTIAKEEPEKFRAFYKAFGTILKIGLNTDFTNRDKLIDLLR
FETTKTVEGEYVTLKEYVGRMAEGQTEIYYHSGSSRAQMLAHPNLEYFRKRDIEVLLLSDPVDVFVIPSIFEYDKKPLKS
IEKAEIDMSTVEPEGERLSAEGTVGVISLFKEVLGERVADVVESRRLVSSPVTLVSGKDALDSQFEKMMKMMNKDADMPS
TKKILEINTAHPIIRNLAGKHAVGLSTDPVVRAAVTQLFESALLLEGDLESVADYVSRMNELVEAATRS

Sequences:

>Translated_629_residues
MSSNPTSSVREFEYKAEMKQLLNLIVHSLYTHPEIFLRELISNASDALGKARFRMLSSDEGLDKSGDLKITITVDKESGS
FVIEDTGIGMSEEELISNLGTVASSGTLGFMEALKEQQKEGQRLDANLIGQFGVGFYSVFMVTDEVTVETKSIESGLQGW
RWKSSGQGSYTIEPVEREARGTRISFILKEEFREFAQEYRVEQIIKKYSNFVEYPIYIGSRQINSMTALWQRPKSELKQE
EVNEFYKFIANDFKDPLDYLHVSVEGAVSFKALLFIPSEAPMELLYNQGALEKRGPQLYVKKVLIQHECRDLLPEYLRFV
SGVVDTEDLPLNVSRELVQASPVMAKIKQILTTKLLGWFDTIAKEEPEKFRAFYKAFGTILKIGLNTDFTNRDKLIDLLR
FETTKTVEGEYVTLKEYVGRMAEGQTEIYYHSGSSRAQMLAHPNLEYFRKRDIEVLLLSDPVDVFVIPSIFEYDKKPLKS
IEKAEIDMSTVEPEGERLSAEGTVGVISLFKEVLGERVADVVESRRLVSSPVTLVSGKDALDSQFEKMMKMMNKDADMPS
TKKILEINTAHPIIRNLAGKHAVGLSTDPVVRAAVTQLFESALLLEGDLESVADYVSRMNELVEAATRS
>Mature_628_residues
SSNPTSSVREFEYKAEMKQLLNLIVHSLYTHPEIFLRELISNASDALGKARFRMLSSDEGLDKSGDLKITITVDKESGSF
VIEDTGIGMSEEELISNLGTVASSGTLGFMEALKEQQKEGQRLDANLIGQFGVGFYSVFMVTDEVTVETKSIESGLQGWR
WKSSGQGSYTIEPVEREARGTRISFILKEEFREFAQEYRVEQIIKKYSNFVEYPIYIGSRQINSMTALWQRPKSELKQEE
VNEFYKFIANDFKDPLDYLHVSVEGAVSFKALLFIPSEAPMELLYNQGALEKRGPQLYVKKVLIQHECRDLLPEYLRFVS
GVVDTEDLPLNVSRELVQASPVMAKIKQILTTKLLGWFDTIAKEEPEKFRAFYKAFGTILKIGLNTDFTNRDKLIDLLRF
ETTKTVEGEYVTLKEYVGRMAEGQTEIYYHSGSSRAQMLAHPNLEYFRKRDIEVLLLSDPVDVFVIPSIFEYDKKPLKSI
EKAEIDMSTVEPEGERLSAEGTVGVISLFKEVLGERVADVVESRRLVSSPVTLVSGKDALDSQFEKMMKMMNKDADMPST
KKILEINTAHPIIRNLAGKHAVGLSTDPVVRAAVTQLFESALLLEGDLESVADYVSRMNELVEAATRS

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI155722983, Length=629, Percent_Identity=33.8632750397456, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI4507677, Length=675, Percent_Identity=34.6666666666667, Blast_Score=377, Evalue=1e-104,
Organism=Homo sapiens, GI20149594, Length=416, Percent_Identity=37.7403846153846, Blast_Score=259, Evalue=8e-69,
Organism=Homo sapiens, GI154146191, Length=416, Percent_Identity=36.0576923076923, Blast_Score=249, Evalue=5e-66,
Organism=Homo sapiens, GI153792590, Length=416, Percent_Identity=36.0576923076923, Blast_Score=247, Evalue=2e-65,
Organism=Escherichia coli, GI1786679, Length=628, Percent_Identity=40.2866242038217, Blast_Score=459, Evalue=1e-130,
Organism=Caenorhabditis elegans, GI17559162, Length=681, Percent_Identity=36.8575624082232, Blast_Score=419, Evalue=1e-117,
Organism=Caenorhabditis elegans, GI17542208, Length=660, Percent_Identity=33.3333333333333, Blast_Score=341, Evalue=6e-94,
Organism=Caenorhabditis elegans, GI115535205, Length=642, Percent_Identity=32.7102803738318, Blast_Score=327, Evalue=1e-89,
Organism=Caenorhabditis elegans, GI115535167, Length=452, Percent_Identity=36.0619469026549, Blast_Score=275, Evalue=4e-74,
Organism=Saccharomyces cerevisiae, GI6323840, Length=411, Percent_Identity=37.712895377129, Blast_Score=261, Evalue=2e-70,
Organism=Saccharomyces cerevisiae, GI6325016, Length=411, Percent_Identity=37.4695863746959, Blast_Score=259, Evalue=7e-70,
Organism=Drosophila melanogaster, GI24586016, Length=639, Percent_Identity=37.0892018779343, Blast_Score=375, Evalue=1e-104,
Organism=Drosophila melanogaster, GI21357739, Length=680, Percent_Identity=33.9705882352941, Blast_Score=339, Evalue=4e-93,
Organism=Drosophila melanogaster, GI17647529, Length=415, Percent_Identity=35.9036144578313, Blast_Score=255, Evalue=8e-68,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_CHLTE (Q8KE61)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_661723.1
- ProteinModelPortal:   Q8KE61
- GeneID:   1007258
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT0829
- NMPDR:   fig|194439.1.peg.817
- TIGR:   CT0829
- HOGENOM:   HBG631012
- OMA:   RRIFEIN
- ProtClustDB:   PRK05218
- BioCyc:   CTEP194439:CT_0829-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71038; Mature: 70907

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNPTSSVREFEYKAEMKQLLNLIVHSLYTHPEIFLRELISNASDALGKARFRMLSSDE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLDKSGDLKITITVDKESGSFVIEDTGIGMSEEELISNLGTVASSGTLGFMEALKEQQKE
CCCCCCCEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
GQRLDANLIGQFGVGFYSVFMVTDEVTVETKSIESGLQGWRWKSSGQGSYTIEPVEREAR
CCCCCHHHHHHHHHHHEEHEEEECCCEEEHHHHHHHHCCCCCCCCCCCCEEECHHHHCCC
GTRISFILKEEFREFAQEYRVEQIIKKYSNFVEYPIYIGSRQINSMTALWQRPKSELKQE
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHCCHHHHHHH
EVNEFYKFIANDFKDPLDYLHVSVEGAVSFKALLFIPSEAPMELLYNQGALEKRGPQLYV
HHHHHHHHHHHHHCCHHHHHEEEECCCEEEEEEEEECCCCCHHHHHCCCCCHHCCHHHHH
KKVLIQHECRDLLPEYLRFVSGVVDTEDLPLNVSRELVQASPVMAKIKQILTTKLLGWFD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHH
TIAKEEPEKFRAFYKAFGTILKIGLNTDFTNRDKLIDLLRFETTKTVEGEYVTLKEYVGR
HHHCCCHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEHHHHHHH
MAEGQTEIYYHSGSSRAQMLAHPNLEYFRKRDIEVLLLSDPVDVFVIPSIFEYDKKPLKS
HHCCCEEEEEECCCCCHHHHCCCCHHHHHCCCCEEEEEECCCCEEECCHHHHHCCHHHHH
IEKAEIDMSTVEPEGERLSAEGTVGVISLFKEVLGERVADVVESRRLVSSPVTLVSGKDA
HHHHHCCHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHH
LDSQFEKMMKMMNKDADMPSTKKILEINTAHPIIRNLAGKHAVGLSTDPVVRAAVTQLFE
HHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
SALLLEGDLESVADYVSRMNELVEAATRS
HHHHHCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SSNPTSSVREFEYKAEMKQLLNLIVHSLYTHPEIFLRELISNASDALGKARFRMLSSDE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
GLDKSGDLKITITVDKESGSFVIEDTGIGMSEEELISNLGTVASSGTLGFMEALKEQQKE
CCCCCCCEEEEEEEECCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
GQRLDANLIGQFGVGFYSVFMVTDEVTVETKSIESGLQGWRWKSSGQGSYTIEPVEREAR
CCCCCHHHHHHHHHHHEEHEEEECCCEEEHHHHHHHHCCCCCCCCCCCCEEECHHHHCCC
GTRISFILKEEFREFAQEYRVEQIIKKYSNFVEYPIYIGSRQINSMTALWQRPKSELKQE
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCHHHHHHHHHHCCHHHHHHH
EVNEFYKFIANDFKDPLDYLHVSVEGAVSFKALLFIPSEAPMELLYNQGALEKRGPQLYV
HHHHHHHHHHHHHCCHHHHHEEEECCCEEEEEEEEECCCCCHHHHHCCCCCHHCCHHHHH
KKVLIQHECRDLLPEYLRFVSGVVDTEDLPLNVSRELVQASPVMAKIKQILTTKLLGWFD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHH
TIAKEEPEKFRAFYKAFGTILKIGLNTDFTNRDKLIDLLRFETTKTVEGEYVTLKEYVGR
HHHCCCHHHHHHHHHHHHHHHEECCCCCCCCHHHHHHHHHHCCCCCCCCCEEEHHHHHHH
MAEGQTEIYYHSGSSRAQMLAHPNLEYFRKRDIEVLLLSDPVDVFVIPSIFEYDKKPLKS
HHCCCEEEEEECCCCCHHHHCCCCHHHHHCCCCEEEEEECCCCEEECCHHHHHCCHHHHH
IEKAEIDMSTVEPEGERLSAEGTVGVISLFKEVLGERVADVVESRRLVSSPVTLVSGKDA
HHHHHCCHHCCCCCCCEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHH
LDSQFEKMMKMMNKDADMPSTKKILEINTAHPIIRNLAGKHAVGLSTDPVVRAAVTQLFE
HHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHH
SALLLEGDLESVADYVSRMNELVEAATRS
HHHHHCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12093901