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The map label for this gene is 21673590

Identifier: 21673590

GI number: 21673590

Start: 735406

End: 735930

Strand: Reverse

Name: 21673590

Synonym: CT0760

Alternate gene names: NA

Gene position: 735930-735406 (Counterclockwise)

Preceding gene: 21673611

Following gene: 21673589

Centisome position: 34.15

GC content: 55.43

Gene sequence:

>525_bases
ATGCAAAGAATGTACTCACCGTGGCGCGACGTCTACATGCAGACCTTCAAGGAAGAAAAGCCTTTCACTCCAGAGGAGGG
CAAATCGGTGTTCGCCGACATTCCGCCCGAACAGGACGAGGAGCGCTACGTGCTTTGCCGGGGTGAATTCTGCTTCGCCA
TCCTGAACCTCTACCCGTACAACTGCGGCCACCTGATGGTCATCCCCTACTTGCAGACACCGGATTTTGGCGATCTTGAC
GCTCAAACGATGGTCGAGATTTTCAACATGTCCAACCTCTGCATGAAGGCGCTGAAAATGACCATCAAACCGCAAGGGTT
CAACTTCGGCGCGAACCTCGGGCGGGTTGCGGGAGGTAGCATTGACGAGCACATTCACTTCCACATCGTACCCCGATGGG
AAGGCGACACCAACTTCATGCCGGTGCTCGGCGAAACCAAGGTGCTCTCGAACGACCTGCGCCAGACCTACATCCAACTC
CGCGAGGCGATCAAGAAGCTTCAAAGCGAACCGAAAAAGCCGTAG

Upstream 100 bases:

>100_bases
CCACTAGGGCATTCCCGGAAACTCTCATAATCATCACTGTCCCGACTTGGCGGGATAAACGCAGCAACCGGATAGCGCAA
CAGATTAGCAGAAATTCCCT

Downstream 100 bases:

>100_bases
TTCCGGAAAATGGAAACCGTCCCCTGCCCAATCACTGGAAGCAGGGAGTTCACCCCCTTTCTGCAAGCCCTCGACCGATT
TAACCTGCACGGCGAGCCTT

Product: Hit family protein

Products: NA

Alternate protein names: ATP adenylyltransferase; Diadenosine 5',5'''-P1,P4-tetraphosphate phosphorylase; AP,A phosphorylase [H]

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MQRMYSPWRDVYMQTFKEEKPFTPEEGKSVFADIPPEQDEERYVLCRGEFCFAILNLYPYNCGHLMVIPYLQTPDFGDLD
AQTMVEIFNMSNLCMKALKMTIKPQGFNFGANLGRVAGGSIDEHIHFHIVPRWEGDTNFMPVLGETKVLSNDLRQTYIQL
REAIKKLQSEPKKP

Sequences:

>Translated_174_residues
MQRMYSPWRDVYMQTFKEEKPFTPEEGKSVFADIPPEQDEERYVLCRGEFCFAILNLYPYNCGHLMVIPYLQTPDFGDLD
AQTMVEIFNMSNLCMKALKMTIKPQGFNFGANLGRVAGGSIDEHIHFHIVPRWEGDTNFMPVLGETKVLSNDLRQTYIQL
REAIKKLQSEPKKP
>Mature_174_residues
MQRMYSPWRDVYMQTFKEEKPFTPEEGKSVFADIPPEQDEERYVLCRGEFCFAILNLYPYNCGHLMVIPYLQTPDFGDLD
AQTMVEIFNMSNLCMKALKMTIKPQGFNFGANLGRVAGGSIDEHIHFHIVPRWEGDTNFMPVLGETKVLSNDLRQTYIQL
REAIKKLQSEPKKP

Specific function: Catabolizes diadenosine 5',5'''-P1,P4-tetraphosphate (Ap4A) into ADP and ATP. It does not catalyze the reverse phosphorolysis reaction. The optimum substrates are dinucleoside polyphosphates containing four or five phosphate residues [H]

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR001310 [H]

Pfam domain/function: PF01230 HIT [H]

EC number: =2.7.7.53 [H]

Molecular weight: Translated: 20190; Mature: 20190

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
7.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRMYSPWRDVYMQTFKEEKPFTPEEGKSVFADIPPEQDEERYVLCRGEFCFAILNLYPY
CCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCEEEEECHHHHHHHHHCCC
NCGHLMVIPYLQTPDFGDLDAQTMVEIFNMSNLCMKALKMTIKPQGFNFGANLGRVAGGS
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
IDEHIHFHIVPRWEGDTNFMPVLGETKVLSNDLRQTYIQLREAIKKLQSEPKKP
CCCCEEEEEEECCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQRMYSPWRDVYMQTFKEEKPFTPEEGKSVFADIPPEQDEERYVLCRGEFCFAILNLYPY
CCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCCCCEEEEECHHHHHHHHHCCC
NCGHLMVIPYLQTPDFGDLDAQTMVEIFNMSNLCMKALKMTIKPQGFNFGANLGRVAGGS
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
IDEHIHFHIVPRWEGDTNFMPVLGETKVLSNDLRQTYIQLREAIKKLQSEPKKP
CCCCEEEEEEECCCCCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036 [H]