Click here to switch to the map view.

The map label for this gene is arpC [H]

Identifier: 21673588

GI number: 21673588

Start: 732932

End: 734374

Strand: Direct

Name: arpC [H]

Synonym: CT0758

Alternate gene names: 21673588

Gene position: 732932-734374 (Clockwise)

Preceding gene: 21673587

Following gene: 21673591

Centisome position: 34.01

GC content: 59.67

Gene sequence:

>1443_bases
TTGGATCGCGCTGGAGGTGGTGGTATATTTGGAGCACCTTACAACAAACAGAATGCCGTCATGAACCTGCACAGAATAAT
CGCGCTTCTCGTTCTCTTTTTCGTATGCTCAACTCCCGTCCACGCTGCGGATGGAACGGAGCCGACGGCAAGGCCGCCGC
TCGTCATCAGCCTTGACGATGCGGTGAGGATCGGGGAGCAGCATAACCGGGAGCTGGAGATTGCGCGGCTGGACAAGCTA
ATGGCGAGGCAGAAGGTTCGGGAGTCTTGGGCCGAGGTGCTGCCGCATCTTTCGTCGAGCCTGACTTACACCCGCACGCT
GAAGCCGTCGGTGCTGTTCCTGCCGTCGAGCATTTTTGGCGGCACGGGAGGTACGCAAGCAATCGAAATCAGTTCGGACA
ATTCATCCATCGCGTCGCTCAATCTCAGTCAGAACATATTCAAGCTCTCGGCCTTCGCGGGCATCAAGGCTGCCGGGCTG
GTGCGCCAGATCAGCGACCAGTCCTTTCGCAATACCAACGCCGGGGTGGTCACCTCGATTCGCCGCGCCTATTACGATGT
GCTCATCGCCACCGAAAAGCGCAAGCTGGTTGAGCAGAGCATCGCCCGCTGGGAGGAGGCTCGCAAGGATACGAACGCCC
TCTTCAGGCAGGGGGTAGCTGCTGACATCGATACCCTCAAGGCGTGGCTGTCGGTCGAGAATCTCAGGCCTGACCTGATT
CGCGCGCAGAACAACGAAGCGATTACGGCGACCAATCTGAAGCGGGTGATGGGCATCGATCAGGAGACGCCGCTGATCCT
GACGAGTACGTTGACATTCCACGAAATCGAAATGCCGAAAAGCGTGGCGGCAGCATACAGCGAAGCGCTCGACAAGCGTC
CGGATGTGCGGAGCCTCTCGCTTCAGGCAGAAGCCGAGAACGCGAAGGTGATGGCCGCCCGATCCGAGGGGCTGCCGGTG
CTGAGCGCTTTCGGGCAGCTCGAAGCGCAGACGCAGTTCAACGATGGCACCTCGCTCGCCTCGACGCGCTGGCCGGTTTC
ATCGACGGCGGGTTTGCAGCTTTCGGTGCCGATTTTCTCCGGCTTCGCTACGAGTGCGAGGATTCAACAGGCGAAGATTA
CGCGCTTGCAGACCAGCACAAGGTATGAAGACCTGAAGTCGCAGGTCAGGGCCGACGTCGAGGTGCGCCTCTCGAACGTC
GTTGAAGCTCGCAAGCGCATCGACGTGCAGTCGAAAACCATCGCCGTCGCCGAGCGGAGTTATAAAATCACCATGCTGCG
CCTTCGCGAAGGCATTGGCTCGCGCCTCGAGCTCACCGACGCCGAGTTGCAGCTCGATACCGCCAAAGCCAACTATCTCC
AGGCAGTGTATGACTACCTTGTCGCGTCGGCGGAGCTGGAAAAGGCGCTGGGAAGGATCGAGCCGACCGAGTCGAAGCTG
TGA

Upstream 100 bases:

>100_bases
GATGGAGCCAAAAGCTTACTACCGCCCAACCGGCGAGGGCCGCGAAAAGTTCATCCGTGAACGGCTGGAGGGGTTGTGGA
AGGATCGATATGGGGATTGA

Downstream 100 bases:

>100_bases
ATGGCGATGAGCTGAAATCGAGATCGAAATCGGTTATTTCTTCAGGGCAGCCCCTTTGCGGCTGCCCTTTGTATTGCTGG
CGACTATCGCTTCATTCTGA

Product: outer membrane efflux protein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MDRAGGGGIFGAPYNKQNAVMNLHRIIALLVLFFVCSTPVHAADGTEPTARPPLVISLDDAVRIGEQHNRELEIARLDKL
MARQKVRESWAEVLPHLSSSLTYTRTLKPSVLFLPSSIFGGTGGTQAIEISSDNSSIASLNLSQNIFKLSAFAGIKAAGL
VRQISDQSFRNTNAGVVTSIRRAYYDVLIATEKRKLVEQSIARWEEARKDTNALFRQGVAADIDTLKAWLSVENLRPDLI
RAQNNEAITATNLKRVMGIDQETPLILTSTLTFHEIEMPKSVAAAYSEALDKRPDVRSLSLQAEAENAKVMAARSEGLPV
LSAFGQLEAQTQFNDGTSLASTRWPVSSTAGLQLSVPIFSGFATSARIQQAKITRLQTSTRYEDLKSQVRADVEVRLSNV
VEARKRIDVQSKTIAVAERSYKITMLRLREGIGSRLELTDAELQLDTAKANYLQAVYDYLVASAELEKALGRIEPTESKL

Sequences:

>Translated_480_residues
MDRAGGGGIFGAPYNKQNAVMNLHRIIALLVLFFVCSTPVHAADGTEPTARPPLVISLDDAVRIGEQHNRELEIARLDKL
MARQKVRESWAEVLPHLSSSLTYTRTLKPSVLFLPSSIFGGTGGTQAIEISSDNSSIASLNLSQNIFKLSAFAGIKAAGL
VRQISDQSFRNTNAGVVTSIRRAYYDVLIATEKRKLVEQSIARWEEARKDTNALFRQGVAADIDTLKAWLSVENLRPDLI
RAQNNEAITATNLKRVMGIDQETPLILTSTLTFHEIEMPKSVAAAYSEALDKRPDVRSLSLQAEAENAKVMAARSEGLPV
LSAFGQLEAQTQFNDGTSLASTRWPVSSTAGLQLSVPIFSGFATSARIQQAKITRLQTSTRYEDLKSQVRADVEVRLSNV
VEARKRIDVQSKTIAVAERSYKITMLRLREGIGSRLELTDAELQLDTAKANYLQAVYDYLVASAELEKALGRIEPTESKL
>Mature_480_residues
MDRAGGGGIFGAPYNKQNAVMNLHRIIALLVLFFVCSTPVHAADGTEPTARPPLVISLDDAVRIGEQHNRELEIARLDKL
MARQKVRESWAEVLPHLSSSLTYTRTLKPSVLFLPSSIFGGTGGTQAIEISSDNSSIASLNLSQNIFKLSAFAGIKAAGL
VRQISDQSFRNTNAGVVTSIRRAYYDVLIATEKRKLVEQSIARWEEARKDTNALFRQGVAADIDTLKAWLSVENLRPDLI
RAQNNEAITATNLKRVMGIDQETPLILTSTLTFHEIEMPKSVAAAYSEALDKRPDVRSLSLQAEAENAKVMAARSEGLPV
LSAFGQLEAQTQFNDGTSLASTRWPVSSTAGLQLSVPIFSGFATSARIQQAKITRLQTSTRYEDLKSQVRADVEVRLSNV
VEARKRIDVQSKTIAVAERSYKITMLRLREGIGSRLELTDAELQLDTAKANYLQAVYDYLVASAELEKALGRIEPTESKL

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI87082199, Length=432, Percent_Identity=22.6851851851852, Blast_Score=69, Evalue=9e-13,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 52718; Mature: 52718

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRAGGGGIFGAPYNKQNAVMNLHRIIALLVLFFVCSTPVHAADGTEPTARPPLVISLDD
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECH
AVRIGEQHNRELEIARLDKLMARQKVRESWAEVLPHLSSSLTYTRTLKPSVLFLPSSIFG
HHHHCHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCHHCC
GTGGTQAIEISSDNSSIASLNLSQNIFKLSAFAGIKAAGLVRQISDQSFRNTNAGVVTSI
CCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHH
RRAYYDVLIATEKRKLVEQSIARWEEARKDTNALFRQGVAADIDTLKAWLSVENLRPDLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHH
RAQNNEAITATNLKRVMGIDQETPLILTSTLTFHEIEMPKSVAAAYSEALDKRPDVRSLS
CCCCCCEEEHHHHHHHHCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEE
LQAEAENAKVMAARSEGLPVLSAFGQLEAQTQFNDGTSLASTRWPVSSTAGLQLSVPIFS
EEECCCCCEEEEECCCCCHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHC
GFATSARIQQAKITRLQTSTRYEDLKSQVRADVEVRLSNVVEARKRIDVQSKTIAVAERS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCC
YKITMLRLREGIGSRLELTDAELQLDTAKANYLQAVYDYLVASAELEKALGRIEPTESKL
EEEEHHHHHHCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MDRAGGGGIFGAPYNKQNAVMNLHRIIALLVLFFVCSTPVHAADGTEPTARPPLVISLDD
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECH
AVRIGEQHNRELEIARLDKLMARQKVRESWAEVLPHLSSSLTYTRTLKPSVLFLPSSIFG
HHHHCHHCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCHHCC
GTGGTQAIEISSDNSSIASLNLSQNIFKLSAFAGIKAAGLVRQISDQSFRNTNAGVVTSI
CCCCCEEEEEECCCCCEEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHH
RRAYYDVLIATEKRKLVEQSIARWEEARKDTNALFRQGVAADIDTLKAWLSVENLRPDLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHH
RAQNNEAITATNLKRVMGIDQETPLILTSTLTFHEIEMPKSVAAAYSEALDKRPDVRSLS
CCCCCCEEEHHHHHHHHCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEE
LQAEAENAKVMAARSEGLPVLSAFGQLEAQTQFNDGTSLASTRWPVSSTAGLQLSVPIFS
EEECCCCCEEEEECCCCCHHHHHHCCHHCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHC
GFATSARIQQAKITRLQTSTRYEDLKSQVRADVEVRLSNVVEARKRIDVQSKTIAVAERS
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEECCC
YKITMLRLREGIGSRLELTDAELQLDTAKANYLQAVYDYLVASAELEKALGRIEPTESKL
EEEEHHHHHHCCCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]