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The map label for this gene is ald [H]

Identifier: 21673482

GI number: 21673482

Start: 646604

End: 647737

Strand: Reverse

Name: ald [H]

Synonym: CT0650

Alternate gene names: 21673482

Gene position: 647737-646604 (Counterclockwise)

Preceding gene: 21673483

Following gene: 21673480

Centisome position: 30.06

GC content: 58.73

Gene sequence:

>1134_bases
ATGAGCGTCTCCATCGCCATTCCAAAAGAGCGTGCCCAGGACGAACGGCGCGTTGCCATTTCGCCGGCTGGAGTGCAGAT
ACTGGTCGAACAGGGTATCCGGGTGGTGGTAGAAAGCAACGCGGGCTGCTTCTGCAATTTCCATGATCAGGATTATGCCG
AAGCCGGTGCGATCATCGTCACCTCACCTGAGGAACTGTACCCGCAGGCCAACGTCATCGTCAAGGTCTCGCCTCCGCAA
CCCGAAGAGCTGCAACTCCTTTTACCCGGCCAGATGCTCATCTCGGCGGTGCATCTCGGCACCGTCAGCCGCCAGATGCT
CAAGACGCTGATCGACAAGAACATCACCGCGCTCGGCTTCGAGTTCATCGAAACGAGGGATGGCGAGCTGCCCATCGTCA
GAACGCTGAGCGAAATCGCCGGATCGCTGGCCATCCAGACGGCGGCGAAATACCTCGAAACCGGCTATGGCGGCAGCGGT
ATTCTGCTTGGCGGCATCGCGGGCGTACCACCCGCACACGTCACGATCATCGGCGCGGGCACGGTCGGCCTGTTCGCCGC
GCAGGACGCGCTCGGCCTGGGAGCGCAGGTAACGGTCATCGACAAGGAGATCAACCGGCTGCGGCGATTCGAAGCGTTCT
TCAACCGACACCTGGTGACGGCCATCGCCAACGAACACTACATTTCGCAGCTCGCGAAAATGTCCGATGTGATGATCGGC
GCGCTCAGCCCCAAGCTGAAACTGAACAAACCGCTGGTGAGCGAGCAGGTGGTCAAAACCATGAAACCCGGGTCGGTGAT
CATCGACGTTTCGATCGACCAGGGAGCCTGTTTCGCCACCAGCCGTCACACAACGCACACCAACCCGATTTACGTCAAGT
ACGGTGTAACGCACTACTGCGTACCAAACATCCCGTCGGCAGTAGCCAAAACTGCCACGTTCGCGCTGACCAACACGCTT
CTGCCATTCCTGCTGAAGCTGAACGCGCACCAGACCATTCCGGAAATTCTCTGGAACAGCCACAGCCTGCGCAAGGGCAC
CTACCTTTACAAAGGCTACATCACCAAGAAAATCCTCGCCGAACTCACCGATCTTCCTTTCCGCGAAATCGACATGCTGC
TCGCGACTGCATAA

Upstream 100 bases:

>100_bases
GATTTTACTGACGATGGGCTACTCATCCGATTTTGGAACTATCGAATTCGAACTCGGAGTCAAAACTCTCGAACGCTGGT
TGCTCAAACCGGAAAAGACG

Downstream 100 bases:

>100_bases
AAAAGGGCGACCACAAGAACCGCCCCAACATGATCCCATCCGCCAATTTCAGGTCGTCCGCGCACTTCCCAACTCATAGG
TAATCGAGCGCTTTCCCCAA

Product: alanine dehydrogenase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MSVSIAIPKERAQDERRVAISPAGVQILVEQGIRVVVESNAGCFCNFHDQDYAEAGAIIVTSPEELYPQANVIVKVSPPQ
PEELQLLLPGQMLISAVHLGTVSRQMLKTLIDKNITALGFEFIETRDGELPIVRTLSEIAGSLAIQTAAKYLETGYGGSG
ILLGGIAGVPPAHVTIIGAGTVGLFAAQDALGLGAQVTVIDKEINRLRRFEAFFNRHLVTAIANEHYISQLAKMSDVMIG
ALSPKLKLNKPLVSEQVVKTMKPGSVIIDVSIDQGACFATSRHTTHTNPIYVKYGVTHYCVPNIPSAVAKTATFALTNTL
LPFLLKLNAHQTIPEILWNSHSLRKGTYLYKGYITKKILAELTDLPFREIDMLLATA

Sequences:

>Translated_377_residues
MSVSIAIPKERAQDERRVAISPAGVQILVEQGIRVVVESNAGCFCNFHDQDYAEAGAIIVTSPEELYPQANVIVKVSPPQ
PEELQLLLPGQMLISAVHLGTVSRQMLKTLIDKNITALGFEFIETRDGELPIVRTLSEIAGSLAIQTAAKYLETGYGGSG
ILLGGIAGVPPAHVTIIGAGTVGLFAAQDALGLGAQVTVIDKEINRLRRFEAFFNRHLVTAIANEHYISQLAKMSDVMIG
ALSPKLKLNKPLVSEQVVKTMKPGSVIIDVSIDQGACFATSRHTTHTNPIYVKYGVTHYCVPNIPSAVAKTATFALTNTL
LPFLLKLNAHQTIPEILWNSHSLRKGTYLYKGYITKKILAELTDLPFREIDMLLATA
>Mature_376_residues
SVSIAIPKERAQDERRVAISPAGVQILVEQGIRVVVESNAGCFCNFHDQDYAEAGAIIVTSPEELYPQANVIVKVSPPQP
EELQLLLPGQMLISAVHLGTVSRQMLKTLIDKNITALGFEFIETRDGELPIVRTLSEIAGSLAIQTAAKYLETGYGGSGI
LLGGIAGVPPAHVTIIGAGTVGLFAAQDALGLGAQVTVIDKEINRLRRFEAFFNRHLVTAIANEHYISQLAKMSDVMIGA
LSPKLKLNKPLVSEQVVKTMKPGSVIIDVSIDQGACFATSRHTTHTNPIYVKYGVTHYCVPNIPSAVAKTATFALTNTLL
PFLLKLNAHQTIPEILWNSHSLRKGTYLYKGYITKKILAELTDLPFREIDMLLATA

Specific function: This enzyme is a key factor in the assimilation of L- alanine as an energy source through the tricarboxylic acid cycle during sporulation [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=351, Percent_Identity=29.6296296296296, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI122939153, Length=351, Percent_Identity=29.6296296296296, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1787887, Length=293, Percent_Identity=31.0580204778157, Blast_Score=105, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17550456, Length=355, Percent_Identity=27.887323943662, Blast_Score=136, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 40848; Mature: 40717

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00837 ALADH_PNT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSIAIPKERAQDERRVAISPAGVQILVEQGIRVVVESNAGCFCNFHDQDYAEAGAIIV
CEEEEECCHHHCCCCCEEEECCCCCEEEEECCCEEEEECCCCEEEECCCCCHHHCCEEEE
TSPEELYPQANVIVKVSPPQPEELQLLLPGQMLISAVHLGTVSRQMLKTLIDKNITALGF
ECCHHHCCCCCEEEEECCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCH
EFIETRDGELPIVRTLSEIAGSLAIQTAAKYLETGYGGSGILLGGIAGVPPAHVTIIGAG
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEECC
TVGLFAAQDALGLGAQVTVIDKEINRLRRFEAFFNRHLVTAIANEHYISQLAKMSDVMIG
CHHHEEHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ALSPKLKLNKPLVSEQVVKTMKPGSVIIDVSIDQGACFATSRHTTHTNPIYVKYGVTHYC
CCCCCEECCCCHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCCCEEEEEECCEEEE
VPNIPSAVAKTATFALTNTLLPFLLKLNAHQTIPEILWNSHSLRKGTYLYKGYITKKILA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEHHHHHHHHHH
ELTDLPFREIDMLLATA
HHHCCCHHHHHHHHHCC
>Mature Secondary Structure 
SVSIAIPKERAQDERRVAISPAGVQILVEQGIRVVVESNAGCFCNFHDQDYAEAGAIIV
EEEEECCHHHCCCCCEEEECCCCCEEEEECCCEEEEECCCCEEEECCCCCHHHCCEEEE
TSPEELYPQANVIVKVSPPQPEELQLLLPGQMLISAVHLGTVSRQMLKTLIDKNITALGF
ECCHHHCCCCCEEEEECCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCH
EFIETRDGELPIVRTLSEIAGSLAIQTAAKYLETGYGGSGILLGGIAGVPPAHVTIIGAG
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCEEEEEECC
TVGLFAAQDALGLGAQVTVIDKEINRLRRFEAFFNRHLVTAIANEHYISQLAKMSDVMIG
CHHHEEHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ALSPKLKLNKPLVSEQVVKTMKPGSVIIDVSIDQGACFATSRHTTHTNPIYVKYGVTHYC
CCCCCEECCCCHHHHHHHHHCCCCCEEEEEEECCCCEEEECCCCCCCCEEEEEECCEEEE
VPNIPSAVAKTATFALTNTLLPFLLKLNAHQTIPEILWNSHSLRKGTYLYKGYITKKILA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCEEEHHHHHHHHHH
ELTDLPFREIDMLLATA
HHHCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2340274 [H]