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The map label for this gene is crtI [H]

Identifier: 21673481

GI number: 21673481

Start: 645028

End: 646530

Strand: Direct

Name: crtI [H]

Synonym: CT0649

Alternate gene names: 21673481

Gene position: 645028-646530 (Clockwise)

Preceding gene: 21673477

Following gene: 21673487

Centisome position: 29.93

GC content: 59.28

Gene sequence:

>1503_bases
ATGGTTGATGTCATTGTCATTGGGGCGGGTATCGGAGGCCTGACGGCGGCTGCGTTGTTGCAGGAGCGAGGTTTTTCAAC
CGTCGTTTTCGAAAAGAACAGGTTTCCCGGTGGGAGCTGTTCGTCGTTTGAGAAGGGAGGTTACACCTTCGATGCCGGAG
CTTCGGTGTTTTACGGTTTCTGCGATGACGACGCAATGGGCACGCTTAACCTGCATTCACGGATTTTCCGCAAGCTCGGT
ATTGCGGTCGAGACTATTCCCGATCCGGTGCAGATTCATTACCACATGCCGGGGGGCTTCGACGTCCCGGCCTGGTTTGA
CCGCGACCGTTTTCTCGAATCGCTCTGCCGCCGGTTTCCGCACGAACGGACGGGCATCCGGAAATTTTACGACGAGCTCG
AATCGGTCTATGAGATTTTGAATTCATTGCCCGCTGGGTCGCTCGAAGATGTGATACACCTGGGCGTTGTCGGTGCCCGC
CATCCGCTGAAGGTCATGGCACTTGGCGTCAAGACGCTCTTTTCGATGGGCAACGTAGCGCGGCGTTACATCAGCGACAA
AGAGCTGCTGCGCTTCATCGATCTCGAAGCCTACTCGTGGGCGGTGCAGGACGCGGTTTCAACCCCGCTGGTCAACGCGG
GCATCTGCCTGGCCGACCGGCACCATGGAGGAATCAACTATCCCGTCGGTGGCTCGGGAACCATTCCGGCGGCGCTGGTG
AAGGGGTTCGAAAAATTCGGCGGGTCGATCCGGTTTGGCAGCGAAGTGTCGAAGGTGATCGTCAAGAACGGCTCGGCGGT
CGGCGTTCGTCTCTCTGACGGCACGGAAGTGAGTGCGAAGGCGGTGGTCAGCAACGCCACGGTGTGGGACACCTTCAGTA
AGCTCGTGGACGATCCCCGTTTGCGGATTCCGGATGATCGTTTCATCAAGGCTCCGAGCTGGTTCCAGATCTGGCTTGGC
GTGGACGGTTCGATCGTGCCGCCGGGGTTCCACATGCATCACATCATTGTCGATGACTGGTCGAAGTACGACGAGCTTGG
CGGCACGATCTACTTCTCTGCGCCCTCGGTGCTCGACCCGTCGCTCGCGCCGCCGGGCAAGCACGCCCTGCACCTCTTTG
TGACTGCTGAGACGTGGCAGTGGGAGCAGTATGAATACCGGAGCCAGGAGTACAAGGCAGCCAAAGAGGCTTTCGCAAAA
TCACTCATCGCGAGAGCCGAGCGCCTCCTGCCGGGAATTCAGGATGCCACCGAACTTATGGTAACCGCCACGCCGCAGAG
CCATGCGCGCTACCTCAATCGTCGCGACGGCTCGTATGGCCCGCTGCTTAAGCCGGGACAGAACATCCTTTTGAAGCCGC
AGAACCGCACGCCGATAAAGAATTTGTTCGCCGCCGGAGACAGTACCTTCCCCGGCCAGGGGGTGATTGCCGTGACCTAC
TCCGGCGTGTCGTGCGCCTCGTACATCGCGCGGCAGTTGGGGAAAGCGCTCGATTACCTATGA

Upstream 100 bases:

>100_bases
TATAAAAATATATCTTTAGAGAAATTTGAGTCAATCGCCAAATGATGGTTTTGTGGCGGATAGTTTGGCTCGGTACAAAA
AAGTGTGAAAGATGGCTGAA

Downstream 100 bases:

>100_bases
GTTGGGAAGTGCGCGGACGACCTGAAATTGGCGGATGGGATCATGTTGGGGCGGTTCTTGTGGTCGCCCTTTTTTATGCA
GTCGCGAGCAGCATGTCGAT

Product: carotenoid isomerase, putative

Products: NA

Alternate protein names: Phytoene desaturase [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MVDVIVIGAGIGGLTAAALLQERGFSTVVFEKNRFPGGSCSSFEKGGYTFDAGASVFYGFCDDDAMGTLNLHSRIFRKLG
IAVETIPDPVQIHYHMPGGFDVPAWFDRDRFLESLCRRFPHERTGIRKFYDELESVYEILNSLPAGSLEDVIHLGVVGAR
HPLKVMALGVKTLFSMGNVARRYISDKELLRFIDLEAYSWAVQDAVSTPLVNAGICLADRHHGGINYPVGGSGTIPAALV
KGFEKFGGSIRFGSEVSKVIVKNGSAVGVRLSDGTEVSAKAVVSNATVWDTFSKLVDDPRLRIPDDRFIKAPSWFQIWLG
VDGSIVPPGFHMHHIIVDDWSKYDELGGTIYFSAPSVLDPSLAPPGKHALHLFVTAETWQWEQYEYRSQEYKAAKEAFAK
SLIARAERLLPGIQDATELMVTATPQSHARYLNRRDGSYGPLLKPGQNILLKPQNRTPIKNLFAAGDSTFPGQGVIAVTY
SGVSCASYIARQLGKALDYL

Sequences:

>Translated_500_residues
MVDVIVIGAGIGGLTAAALLQERGFSTVVFEKNRFPGGSCSSFEKGGYTFDAGASVFYGFCDDDAMGTLNLHSRIFRKLG
IAVETIPDPVQIHYHMPGGFDVPAWFDRDRFLESLCRRFPHERTGIRKFYDELESVYEILNSLPAGSLEDVIHLGVVGAR
HPLKVMALGVKTLFSMGNVARRYISDKELLRFIDLEAYSWAVQDAVSTPLVNAGICLADRHHGGINYPVGGSGTIPAALV
KGFEKFGGSIRFGSEVSKVIVKNGSAVGVRLSDGTEVSAKAVVSNATVWDTFSKLVDDPRLRIPDDRFIKAPSWFQIWLG
VDGSIVPPGFHMHHIIVDDWSKYDELGGTIYFSAPSVLDPSLAPPGKHALHLFVTAETWQWEQYEYRSQEYKAAKEAFAK
SLIARAERLLPGIQDATELMVTATPQSHARYLNRRDGSYGPLLKPGQNILLKPQNRTPIKNLFAAGDSTFPGQGVIAVTY
SGVSCASYIARQLGKALDYL
>Mature_500_residues
MVDVIVIGAGIGGLTAAALLQERGFSTVVFEKNRFPGGSCSSFEKGGYTFDAGASVFYGFCDDDAMGTLNLHSRIFRKLG
IAVETIPDPVQIHYHMPGGFDVPAWFDRDRFLESLCRRFPHERTGIRKFYDELESVYEILNSLPAGSLEDVIHLGVVGAR
HPLKVMALGVKTLFSMGNVARRYISDKELLRFIDLEAYSWAVQDAVSTPLVNAGICLADRHHGGINYPVGGSGTIPAALV
KGFEKFGGSIRFGSEVSKVIVKNGSAVGVRLSDGTEVSAKAVVSNATVWDTFSKLVDDPRLRIPDDRFIKAPSWFQIWLG
VDGSIVPPGFHMHHIIVDDWSKYDELGGTIYFSAPSVLDPSLAPPGKHALHLFVTAETWQWEQYEYRSQEYKAAKEAFAK
SLIARAERLLPGIQDATELMVTATPQSHARYLNRRDGSYGPLLKPGQNILLKPQNRTPIKNLFAAGDSTFPGQGVIAVTY
SGVSCASYIARQLGKALDYL

Specific function: This enzyme converts phytoene into lycopene via the intermediaries of phytofluene, zeta-carotene and neurosporene by the introduction of four double bonds [H]

COG id: COG1233

COG function: function code Q; Phytoene dehydrogenase and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carotenoid/retinoid oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI203098013, Length=532, Percent_Identity=22.7443609022556, Blast_Score=87, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR008150
- InterPro:   IPR014105 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: NA

Molecular weight: Translated: 54781; Mature: 54781

Theoretical pI: Translated: 7.21; Mature: 7.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDVIVIGAGIGGLTAAALLQERGFSTVVFEKNRFPGGSCSSFEKGGYTFDAGASVFYGF
CEEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEEECCCCEEEEE
CDDDAMGTLNLHSRIFRKLGIAVETIPDPVQIHYHMPGGFDVPAWFDRDRFLESLCRRFP
CCCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCC
HERTGIRKFYDELESVYEILNSLPAGSLEDVIHLGVVGARHPLKVMALGVKTLFSMGNVA
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
RRYISDKELLRFIDLEAYSWAVQDAVSTPLVNAGICLADRHHGGINYPVGGSGTIPAALV
HHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHH
KGFEKFGGSIRFGSEVSKVIVKNGSAVGVRLSDGTEVSAKAVVSNATVWDTFSKLVDDPR
HHHHHHCCCEEECHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHCCCC
LRIPDDRFIKAPSWFQIWLGVDGSIVPPGFHMHHIIVDDWSKYDELGGTIYFSAPSVLDP
CCCCCCCEECCCCEEEEEECCCCCCCCCCCCEEEEEECCCHHHHHCCCEEEECCCCCCCC
SLAPPGKHALHLFVTAETWQWEQYEYRSQEYKAAKEAFAKSLIARAERLLPGIQDATELM
CCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VTATPQSHARYLNRRDGSYGPLLKPGQNILLKPQNRTPIKNLFAAGDSTFPGQGVIAVTY
EECCCHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHCCCCCCCCCCEEEEEE
SGVSCASYIARQLGKALDYL
CCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVDVIVIGAGIGGLTAAALLQERGFSTVVFEKNRFPGGSCSSFEKGGYTFDAGASVFYGF
CEEEEEEECCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCEEEECCCCEEEEE
CDDDAMGTLNLHSRIFRKLGIAVETIPDPVQIHYHMPGGFDVPAWFDRDRFLESLCRRFP
CCCCCCCCHHHHHHHHHHHCCEEECCCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHCC
HERTGIRKFYDELESVYEILNSLPAGSLEDVIHLGVVGARHPLKVMALGVKTLFSMGNVA
CCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
RRYISDKELLRFIDLEAYSWAVQDAVSTPLVNAGICLADRHHGGINYPVGGSGTIPAALV
HHHHCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHH
KGFEKFGGSIRFGSEVSKVIVKNGSAVGVRLSDGTEVSAKAVVSNATVWDTFSKLVDDPR
HHHHHHCCCEEECHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHCCCC
LRIPDDRFIKAPSWFQIWLGVDGSIVPPGFHMHHIIVDDWSKYDELGGTIYFSAPSVLDP
CCCCCCCEECCCCEEEEEECCCCCCCCCCCCEEEEEECCCHHHHHCCCEEEECCCCCCCC
SLAPPGKHALHLFVTAETWQWEQYEYRSQEYKAAKEAFAKSLIARAERLLPGIQDATELM
CCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
VTATPQSHARYLNRRDGSYGPLLKPGQNILLKPQNRTPIKNLFAAGDSTFPGQGVIAVTY
EECCCHHHHHHHHCCCCCCCCCCCCCCCEEECCCCCCCHHHHHHCCCCCCCCCCEEEEEE
SGVSCASYIARQLGKALDYL
CCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2263648 [H]