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The map label for this gene is ytfL [C]

Identifier: 21673376

GI number: 21673376

Start: 547960

End: 549279

Strand: Reverse

Name: ytfL [C]

Synonym: CT0541

Alternate gene names: 21673376

Gene position: 549279-547960 (Counterclockwise)

Preceding gene: 21673377

Following gene: 21673375

Centisome position: 25.49

GC content: 59.85

Gene sequence:

>1320_bases
ATGGAAATCTTTTTTCTTTTCTTACTGCTGATTCTGATCAACGGCCTTTTCGCCATGTCGGAGATGGCCCTGATTACTGC
GAAGCGTTCGCGCCTCGCCAAGCTTGCCGAAGATGGCGACAAGGCGGCAGCGGCAGCCATCAAGCTCGGCCATGAACCGA
CGCAATTTCTTTCAACCGTACAGATCGGCCTGACGGTCATCGGTGTGCTCAACGGTTTCATCGGCGAATCATCATTCACG
CCACCTCTGGCAGCCGCGCTCGAATTGTACGGCGGCTGGGACCCGAAAACGAGCCATATTATCGCCACCGTGCTGGTGGT
CATCGTGATTACGTATATCACCATCGTCATCGGCGAGCTGGTGCCCAAACGACTCGGCCAGACCGACCCGGAAGGCATTG
CCCGCAACGTTGCGCGTCCGATGCAAATCCTCGCCACCGCAACCCGCCCATTCGTACGCCTGCTCTCGGCATCGACTGAT
GCCATTCTGCGCCTCATGGGCAAGCATGAACAAACCCAGCCCAGCGTCACCGAAGAGGAGATTCACGCCATGCTCGAAGA
GGGCTCCGTCGCGGGCATTATCGAGCAGCAGGAGCACGAGATGGTGCGCAACGTCTTCCGCCTCGACGACCGGCAGCTCG
GTTCGCTCATGGTGCCGCGCGCGGACATCATCTATCTCGACACCGCCCTGCCGCTCGAAGAGAACATGAAGCGCGTCGTC
GAGTCGGAGCATTCGCGCTTCCCGGTCTGCCACAACGGTTTGCAGTCGCTGCTCGGCGTGGTCAATGCCAAGCAGCTGCT
CGCCCAGACCATCAAGGGCGGCGTCACCAACCTGGCTGAACATCTTCAGCCCTGCGTCTACGTGCCCGAAACGCTGACCG
GCATGGAGCTGCTCGACCATTTCAGGACGTCGGGAACACAGATGGTATTCGTGGTGGACGAGTATGGCGAAATCCAGGGT
CTCGTGACGTTACAGGACATGCTCGAAGCGGTCACGGGCGAGTTCGCACCGCTCAACCTCGAAGACGCTTGGGCTGTGCA
GCGCGAGGATGGCTCGTGGCTGCTCGATGGCCTGATTGCCGTGCCGGAGCTGAAAGACACGCTCGGCCTGCGCGCCGTGC
CGGAGGAGGAGAAAGGGGTCTATCACACCCTGAGCGGCATGATCATGTGGCTGCTCGGACGCCTGCCGCAAACCGGCGAC
ATCACCTTCTGGGAGAACTGGCGGCTTGAAGTGATCGACATGGACAGCAAACGCATCGACAAGGTGCTCGCCACCAAAAT
CGATAATCAGCCCACTGAAGACCCAAAACCGGTCGCCTGA

Upstream 100 bases:

>100_bases
CTGAAACCCTTTTTTACAATCTGCCGTTGATAACGTATTATGTCCGTTAAGCGTAACTGCCTTGCGGGGTGGTTACGGTT
TGTGCACCTGACTTAAATCC

Downstream 100 bases:

>100_bases
CCAGCGAGCGCCTCAGGGTTGCCATACAGAATTGTTATCGGTACATTTTCTACAAGAAACAACGTTTATCGAGCAACTCC
TGATTCTGCGGTTCGAAAAG

Product: CBS domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MEIFFLFLLLILINGLFAMSEMALITAKRSRLAKLAEDGDKAAAAAIKLGHEPTQFLSTVQIGLTVIGVLNGFIGESSFT
PPLAAALELYGGWDPKTSHIIATVLVVIVITYITIVIGELVPKRLGQTDPEGIARNVARPMQILATATRPFVRLLSASTD
AILRLMGKHEQTQPSVTEEEIHAMLEEGSVAGIIEQQEHEMVRNVFRLDDRQLGSLMVPRADIIYLDTALPLEENMKRVV
ESEHSRFPVCHNGLQSLLGVVNAKQLLAQTIKGGVTNLAEHLQPCVYVPETLTGMELLDHFRTSGTQMVFVVDEYGEIQG
LVTLQDMLEAVTGEFAPLNLEDAWAVQREDGSWLLDGLIAVPELKDTLGLRAVPEEEKGVYHTLSGMIMWLLGRLPQTGD
ITFWENWRLEVIDMDSKRIDKVLATKIDNQPTEDPKPVA

Sequences:

>Translated_439_residues
MEIFFLFLLLILINGLFAMSEMALITAKRSRLAKLAEDGDKAAAAAIKLGHEPTQFLSTVQIGLTVIGVLNGFIGESSFT
PPLAAALELYGGWDPKTSHIIATVLVVIVITYITIVIGELVPKRLGQTDPEGIARNVARPMQILATATRPFVRLLSASTD
AILRLMGKHEQTQPSVTEEEIHAMLEEGSVAGIIEQQEHEMVRNVFRLDDRQLGSLMVPRADIIYLDTALPLEENMKRVV
ESEHSRFPVCHNGLQSLLGVVNAKQLLAQTIKGGVTNLAEHLQPCVYVPETLTGMELLDHFRTSGTQMVFVVDEYGEIQG
LVTLQDMLEAVTGEFAPLNLEDAWAVQREDGSWLLDGLIAVPELKDTLGLRAVPEEEKGVYHTLSGMIMWLLGRLPQTGD
ITFWENWRLEVIDMDSKRIDKVLATKIDNQPTEDPKPVA
>Mature_439_residues
MEIFFLFLLLILINGLFAMSEMALITAKRSRLAKLAEDGDKAAAAAIKLGHEPTQFLSTVQIGLTVIGVLNGFIGESSFT
PPLAAALELYGGWDPKTSHIIATVLVVIVITYITIVIGELVPKRLGQTDPEGIARNVARPMQILATATRPFVRLLSASTD
AILRLMGKHEQTQPSVTEEEIHAMLEEGSVAGIIEQQEHEMVRNVFRLDDRQLGSLMVPRADIIYLDTALPLEENMKRVV
ESEHSRFPVCHNGLQSLLGVVNAKQLLAQTIKGGVTNLAEHLQPCVYVPETLTGMELLDHFRTSGTQMVFVVDEYGEIQG
LVTLQDMLEAVTGEFAPLNLEDAWAVQREDGSWLLDGLIAVPELKDTLGLRAVPEEEKGVYHTLSGMIMWLLGRLPQTGD
ITFWENWRLEVIDMDSKRIDKVLATKIDNQPTEDPKPVA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=321, Percent_Identity=28.0373831775701, Blast_Score=157, Evalue=1e-38,
Organism=Escherichia coli, GI1790664, Length=427, Percent_Identity=29.7423887587822, Blast_Score=251, Evalue=5e-68,
Organism=Escherichia coli, GI87082033, Length=337, Percent_Identity=31.1572700296736, Blast_Score=135, Evalue=7e-33,
Organism=Escherichia coli, GI145693175, Length=418, Percent_Identity=26.0765550239234, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788119, Length=344, Percent_Identity=29.6511627906977, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1786879, Length=264, Percent_Identity=27.6515151515151, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 48488; Mature: 48488

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIFFLFLLLILINGLFAMSEMALITAKRSRLAKLAEDGDKAAAAAIKLGHEPTQFLSTV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHH
QIGLTVIGVLNGFIGESSFTPPLAAALELYGGWDPKTSHIIATVLVVIVITYITIVIGEL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VPKRLGQTDPEGIARNVARPMQILATATRPFVRLLSASTDAILRLMGKHEQTQPSVTEEE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHH
IHAMLEEGSVAGIIEQQEHEMVRNVFRLDDRQLGSLMVPRADIIYLDTALPLEENMKRVV
HHHHHHCCCEEEHHHHHHHHHHHHHHHCCCHHHCCEECCCCCEEEEECCCCHHHHHHHHH
ESEHSRFPVCHNGLQSLLGVVNAKQLLAQTIKGGVTNLAEHLQPCVYVPETLTGMELLDH
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEECCCHHHHHHHHHH
FRTSGTQMVFVVDEYGEIQGLVTLQDMLEAVTGEFAPLNLEDAWAVQREDGSWLLDGLIA
HHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEECCCCCHHHHHHH
VPELKDTLGLRAVPEEEKGVYHTLSGMIMWLLGRLPQTGDITFWENWRLEVIDMDSKRID
CCCHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCHHHHH
KVLATKIDNQPTEDPKPVA
HHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MEIFFLFLLLILINGLFAMSEMALITAKRSRLAKLAEDGDKAAAAAIKLGHEPTQFLSTV
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHH
QIGLTVIGVLNGFIGESSFTPPLAAALELYGGWDPKTSHIIATVLVVIVITYITIVIGEL
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
VPKRLGQTDPEGIARNVARPMQILATATRPFVRLLSASTDAILRLMGKHEQTQPSVTEEE
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCHHH
IHAMLEEGSVAGIIEQQEHEMVRNVFRLDDRQLGSLMVPRADIIYLDTALPLEENMKRVV
HHHHHHCCCEEEHHHHHHHHHHHHHHHCCCHHHCCEECCCCCEEEEECCCCHHHHHHHHH
ESEHSRFPVCHNGLQSLLGVVNAKQLLAQTIKGGVTNLAEHLQPCVYVPETLTGMELLDH
HHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCEECCCHHHHHHHHHH
FRTSGTQMVFVVDEYGEIQGLVTLQDMLEAVTGEFAPLNLEDAWAVQREDGSWLLDGLIA
HHCCCCEEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHEEEECCCCCHHHHHHH
VPELKDTLGLRAVPEEEKGVYHTLSGMIMWLLGRLPQTGDITFWENWRLEVIDMDSKRID
CCCHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEECCHHHHH
KVLATKIDNQPTEDPKPVA
HHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]