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The map label for this gene is metK [H]

Identifier: 21673375

GI number: 21673375

Start: 546635

End: 547849

Strand: Reverse

Name: metK [H]

Synonym: CT0540

Alternate gene names: 21673375

Gene position: 547849-546635 (Counterclockwise)

Preceding gene: 21673376

Following gene: 21673374

Centisome position: 25.42

GC content: 59.75

Gene sequence:

>1215_bases
ATGAGCGTCCCAAGAAACATCACGATTGAGCGGAGCGAAGCCGTTCCGATGGACCAGCAGCCATTCGAACTGGTCGAGCG
CAAAGGCATCGGACACCCCGACACAATCTGCGATTCGATCATGGAGGCGGTCTGCATCGACCTGTGCCGCGAGTACAACA
GCCGGTTCGGCCACATCTGCCACCACAACATCGACAAGGGCTTGCTCGTGGCAGGCCGGAGCCTTCCAAAAACCGGCGGC
GGCATGATTCTCGAACCGATGAAGCTGATCTTTGGCGACCGCGCCACCTATACCTGTAACGGCCAGCTCGTGCCGGTGGG
CGAAATCGCCGAGGCTGCCGCGAAGCGCTGGATCAGAGAGAACCTGCGGTTCGTCGATCCCGACCAGCACCTGCTCTTCC
AGAACGAAATCAAGCCCGGTTCACCAGAACTGACTGACGCCTTCGCCCGGAAGGTGATCGGCGCAAACGACACCTCGGTC
GGCGTCGGCTATGCGCCCTTCAGCGAAACCGAGCGCATCGTGCTTGCCACCGAGCAGTTCCTCAACTCCCCCGCACTGAA
AGAACGGTTCCCGGAAGCTGGCGAAGACGTCAAAATCATGGGCTGCCGCAACGGAAGAAAGCTGCAACTAACGGTGGCCG
TGGCTTTCGTTGATCGCTTTATCCCGAATGCGAATCACTATTTCGAGCGAAAATCAGCATTGCGCCATGAACTGCTTTCC
TTCATCGAAAGCCAGAGTTGCAACATCGATTCCGTCGCAATCGACATCAACAGCCTCGACGACCCGTCGCGCGGCGAGGA
GGGAGTTTACCTCACGGTACTCGGCACCTCGGCAGAGGGAGGTGACGGCGGACAGGTAGGTCGTGGCAACCGGGTCAACG
GCCTCATCGCGTTCAACCGCAACCAGACGATGGAGGCGGCCGCCGGCAAGAACCCGGTCAACCATGTCGGCAAAATCTAC
AATGTCCTGAGCCATGAACTTGCCCGTCGTATCCACCGCGAAATCGAAGGAGTCGTGTCGGTGACAGTGTTCCTCTGCAG
CCAGATCGGCAAACCGGTTGACCGGCCGCTTATGGCCTCGGCCCGCATCACGCCCGAACCTGGTGCCAACATGGCGGAGC
TGCAAAGTCGCGCCACAAGCATCATCGACCGGGAACTCGACGGGATCGACGCCTTCTGCCAGAAGCTCGCCGACGGAGAA
TTCAGGGTGTGCTGA

Upstream 100 bases:

>100_bases
CCTCAGGGTTGCCATACAGAATTGTTATCGGTACATTTTCTACAAGAAACAACGTTTATCGAGCAACTCCTGATTCTGCG
GTTCGAAAAGACCCGTCGGC

Downstream 100 bases:

>100_bases
ACATTGCGCCAAACCCGTGGGGTGCCAAGAGAAAAATGACGGAAACTGGTCATCGCGATTATACTTCATGTAATGATTGT
GATTGAATAATCATCGTCGT

Product: S-adenosylmethionine synthetase

Products: NA

Alternate protein names: AdoMet synthase; Methionine adenosyltransferase [H]

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MSVPRNITIERSEAVPMDQQPFELVERKGIGHPDTICDSIMEAVCIDLCREYNSRFGHICHHNIDKGLLVAGRSLPKTGG
GMILEPMKLIFGDRATYTCNGQLVPVGEIAEAAAKRWIRENLRFVDPDQHLLFQNEIKPGSPELTDAFARKVIGANDTSV
GVGYAPFSETERIVLATEQFLNSPALKERFPEAGEDVKIMGCRNGRKLQLTVAVAFVDRFIPNANHYFERKSALRHELLS
FIESQSCNIDSVAIDINSLDDPSRGEEGVYLTVLGTSAEGGDGGQVGRGNRVNGLIAFNRNQTMEAAAGKNPVNHVGKIY
NVLSHELARRIHREIEGVVSVTVFLCSQIGKPVDRPLMASARITPEPGANMAELQSRATSIIDRELDGIDAFCQKLADGE
FRVC

Sequences:

>Translated_404_residues
MSVPRNITIERSEAVPMDQQPFELVERKGIGHPDTICDSIMEAVCIDLCREYNSRFGHICHHNIDKGLLVAGRSLPKTGG
GMILEPMKLIFGDRATYTCNGQLVPVGEIAEAAAKRWIRENLRFVDPDQHLLFQNEIKPGSPELTDAFARKVIGANDTSV
GVGYAPFSETERIVLATEQFLNSPALKERFPEAGEDVKIMGCRNGRKLQLTVAVAFVDRFIPNANHYFERKSALRHELLS
FIESQSCNIDSVAIDINSLDDPSRGEEGVYLTVLGTSAEGGDGGQVGRGNRVNGLIAFNRNQTMEAAAGKNPVNHVGKIY
NVLSHELARRIHREIEGVVSVTVFLCSQIGKPVDRPLMASARITPEPGANMAELQSRATSIIDRELDGIDAFCQKLADGE
FRVC
>Mature_403_residues
SVPRNITIERSEAVPMDQQPFELVERKGIGHPDTICDSIMEAVCIDLCREYNSRFGHICHHNIDKGLLVAGRSLPKTGGG
MILEPMKLIFGDRATYTCNGQLVPVGEIAEAAAKRWIRENLRFVDPDQHLLFQNEIKPGSPELTDAFARKVIGANDTSVG
VGYAPFSETERIVLATEQFLNSPALKERFPEAGEDVKIMGCRNGRKLQLTVAVAFVDRFIPNANHYFERKSALRHELLSF
IESQSCNIDSVAIDINSLDDPSRGEEGVYLTVLGTSAEGGDGGQVGRGNRVNGLIAFNRNQTMEAAAGKNPVNHVGKIYN
VLSHELARRIHREIEGVVSVTVFLCSQIGKPVDRPLMASARITPEPGANMAELQSRATSIIDRELDGIDAFCQKLADGEF
RVC

Specific function: Catalyzes the formation of S-adenosylmethionine from methionine and ATP [H]

COG id: COG1812

COG function: function code E; Archaeal S-adenosylmethionine synthetase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AdoMet synthase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002795
- ProDom:   PD011777 [H]

Pfam domain/function: PF01941 AdoMet_Synthase [H]

EC number: =2.5.1.6 [H]

Molecular weight: Translated: 44385; Mature: 44254

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVPRNITIERSEAVPMDQQPFELVERKGIGHPDTICDSIMEAVCIDLCREYNSRFGHIC
CCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
HHNIDKGLLVAGRSLPKTGGGMILEPMKLIFGDRATYTCNGQLVPVGEIAEAAAKRWIRE
HCCCCCCEEEECCCCCCCCCCEEHHHHHHHHCCCCEEEECCEEEEHHHHHHHHHHHHHHH
NLRFVDPDQHLLFQNEIKPGSPELTDAFARKVIGANDTSVGVGYAPFSETERIVLATEQF
CCCEECCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHHHH
LNSPALKERFPEAGEDVKIMGCRNGRKLQLTVAVAFVDRFIPNANHYFERKSALRHELLS
HCCCHHHHHCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FIESQSCNIDSVAIDINSLDDPSRGEEGVYLTVLGTSAEGGDGGQVGRGNRVNGLIAFNR
HHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECC
NQTMEAAAGKNPVNHVGKIYNVLSHELARRIHREIEGVVSVTVFLCSQIGKPVDRPLMAS
CCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHC
ARITPEPGANMAELQSRATSIIDRELDGIDAFCQKLADGEFRVC
CCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECC
>Mature Secondary Structure 
SVPRNITIERSEAVPMDQQPFELVERKGIGHPDTICDSIMEAVCIDLCREYNSRFGHIC
CCCCCEEEECCCCCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHH
HHNIDKGLLVAGRSLPKTGGGMILEPMKLIFGDRATYTCNGQLVPVGEIAEAAAKRWIRE
HCCCCCCEEEECCCCCCCCCCEEHHHHHHHHCCCCEEEECCEEEEHHHHHHHHHHHHHHH
NLRFVDPDQHLLFQNEIKPGSPELTDAFARKVIGANDTSVGVGYAPFSETERIVLATEQF
CCCEECCCCCEEEECCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEEEHHHH
LNSPALKERFPEAGEDVKIMGCRNGRKLQLTVAVAFVDRFIPNANHYFERKSALRHELLS
HCCCHHHHHCCCCCCCEEEEECCCCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHHHHHHH
FIESQSCNIDSVAIDINSLDDPSRGEEGVYLTVLGTSAEGGDGGQVGRGNRVNGLIAFNR
HHHHCCCCCCEEEEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCEEEEECC
NQTMEAAAGKNPVNHVGKIYNVLSHELARRIHREIEGVVSVTVFLCSQIGKPVDRPLMAS
CCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHC
ARITPEPGANMAELQSRATSIIDRELDGIDAFCQKLADGEFRVC
CCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA