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The map label for this gene is groES

Identifier: 21673364

GI number: 21673364

Start: 536376

End: 536663

Strand: Direct

Name: groES

Synonym: CT0529

Alternate gene names: 21673364

Gene position: 536376-536663 (Clockwise)

Preceding gene: 21673362

Following gene: 21673365

Centisome position: 24.89

GC content: 53.82

Gene sequence:

>288_bases
ATGAACTTGAAACCATTAGCTGATCGAGTTATTGTTAAGCCCGCTCCTGCCGAAGAGAAAACCAAGGGTGGGCTCTACAT
TCCCGATACCGGCAAAGAGAAGCCGATGTATGGTGAAGTCGTCGCCGTTGGTCCGGGCAAGGTTTCCGATGCTGGCCAGG
TTGTTGCCATGCAGGTGAAAGCTGGCGACAAGGTCCTTTACGGCAAGTACTCAGGCACCGAAGTCCATGTCGAGGGCGAG
GACTACCTGATCATGCGCGAGTCCGATATCTTCGCGATTCTTGGCTGA

Upstream 100 bases:

>100_bases
CTCTCCCTTATTGAGTGCTAATAGCAGCTGAACCTCGCGTTCAGGCAGTTTCTGATGACAAAAGACGATCTATTAACCAA
ATCAAACGAGAAAGAAGACA

Downstream 100 bases:

>100_bases
CCAATTCACAAACAGTTTTTTTAAATCTTTAAGGAGGAACGCTTTACAATGACTGCTAAAGATATTCTCTTTGACGCCGA
GGCGAGGACCAAACTCAAGG

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MNLKPLADRVIVKPAPAEEKTKGGLYIPDTGKEKPMYGEVVAVGPGKVSDAGQVVAMQVKAGDKVLYGKYSGTEVHVEGE
DYLIMRESDIFAILG

Sequences:

>Translated_95_residues
MNLKPLADRVIVKPAPAEEKTKGGLYIPDTGKEKPMYGEVVAVGPGKVSDAGQVVAMQVKAGDKVLYGKYSGTEVHVEGE
DYLIMRESDIFAILG
>Mature_95_residues
MNLKPLADRVIVKPAPAEEKTKGGLYIPDTGKEKPMYGEVVAVGPGKVSDAGQVVAMQVKAGDKVLYGKYSGTEVHVEGE
DYLIMRESDIFAILG

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Homo sapiens, GI4504523, Length=87, Percent_Identity=42.5287356321839, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790585, Length=95, Percent_Identity=42.1052631578947, Blast_Score=75, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17555568, Length=93, Percent_Identity=44.0860215053763, Blast_Score=82, Evalue=7e-17,
Organism=Saccharomyces cerevisiae, GI6324594, Length=89, Percent_Identity=42.6966292134831, Blast_Score=70, Evalue=8e-14,
Organism=Drosophila melanogaster, GI21356029, Length=93, Percent_Identity=40.8602150537634, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI21358317, Length=92, Percent_Identity=41.304347826087, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_CHLTE (Q8KF03)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_661429.1
- ProteinModelPortal:   Q8KF03
- SMR:   Q8KF03
- GeneID:   1006199
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT0529
- NMPDR:   fig|194439.1.peg.523
- TIGR:   CT0529
- HOGENOM:   HBG703377
- OMA:   GKEKPMY
- ProtClustDB:   PRK00364
- BioCyc:   CTEP194439:CT_0529-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10166; Mature: 10166

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKPLADRVIVKPAPAEEKTKGGLYIPDTGKEKPMYGEVVAVGPGKVSDAGQVVAMQVK
CCCCCCCCEEEECCCCCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEC
AGDKVLYGKYSGTEVHVEGEDYLIMRESDIFAILG
CCCEEEEEECCCCEEEECCCCEEEEECCCEEEEEC
>Mature Secondary Structure
MNLKPLADRVIVKPAPAEEKTKGGLYIPDTGKEKPMYGEVVAVGPGKVSDAGQVVAMQVK
CCCCCCCCEEEECCCCCCCCCCCCEECCCCCCCCCCCCEEEEECCCCCCCCCEEEEEEEC
AGDKVLYGKYSGTEVHVEGEDYLIMRESDIFAILG
CCCEEEEEECCCCEEEECCCCEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901