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The map label for this gene is modD [H]

Identifier: 21673289

GI number: 21673289

Start: 473475

End: 474332

Strand: Reverse

Name: modD [H]

Synonym: CT0453

Alternate gene names: 21673289

Gene position: 474332-473475 (Counterclockwise)

Preceding gene: 21673298

Following gene: 21673288

Centisome position: 22.01

GC content: 64.45

Gene sequence:

>858_bases
ATGTACAGCCTCACCCCCGACAGCGAAATCGAGCGATATATCGAAGAAGACGTGCCTTATGGCGACTTGACCACCACCCT
GCTCGGCATCGGCGATGAACCGGGCGAGATAACCTTCACCACGCGCGACCGGACGGTGCTCTGTTGCACCGAGGAGGCCG
GGCGGGTGCTCGCGAAGTGCGGTGCCGAGGTGCTCTCGATGCTTCCGTCCGGCACGATTGCTGCGCCGGGCACGGAGATT
CTGAGAGCTTCCGGCCCGGCGGCGGCGCTGCACGCGGGCTGGAAGGTGGCGATGAACCTGCTCGAATACGCCTCCGGCAT
CTCGACGCGCACCGCGACCATCGTCGAACGCGCCCGCGCCGCCAACCCCGGCATCAACGTCGTCACGACGCGCAAATCCT
TTCCCGGCACCAAAAAGATCGCCATGAAGGCGATCATGGCAGGCGGCGCGTTTCCCCACCGCCTCGGCCTCTCCGAATCG
ATCCTTGTCTTCAGCCAGCACACCGTCTTTCTTGGCGGACTCGATCCGTTCCTCGACAAGCTCTCCGATCTGAAAAAGCT
CGCGCCGGAACAGAAAATTCTCGTCGAGGCGGACAGCGCCGTCGAGGCGCTCCGCATCGCGGCGGCGGGCGCGGACGTGG
TGCAGGTGGACAAGATGCCGGTCGCCGAACTCGCGGCGCTGGTCTCGGAAATCCGCAGCCGCTTTCCCGGCGTGGCAGTC
TCGGCGGCCGGCGGCATCAACGGCGAAAACGCCGCCGCGTACGCCGCCACCGGCATCGACATCATCGTGCTCTCCTCGGT
TTACTTCGGCAAACCTGCCGACATTTCGACCTCGATCTTGCCAGTAAAATCCAACTGA

Upstream 100 bases:

>100_bases
AAACAACGAAAACAGAACAATTACGCGGACGACACAGAAATTCCAGAACCTGCGCTTTACGCTATAACAGAAATCACATA
ACGTTCTAAAATATTCACGA

Downstream 100 bases:

>100_bases
CAAACCCGAATCATGCAAACCTTGAAGCACTTCATCCGCGCCATCGGCATCGCGCTCAACGTCGTCATACTGACGAGCAT
ACCGGCGCTTGCCGGACAGA

Product: molybdenum transport system protein ModD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MYSLTPDSEIERYIEEDVPYGDLTTTLLGIGDEPGEITFTTRDRTVLCCTEEAGRVLAKCGAEVLSMLPSGTIAAPGTEI
LRASGPAAALHAGWKVAMNLLEYASGISTRTATIVERARAANPGINVVTTRKSFPGTKKIAMKAIMAGGAFPHRLGLSES
ILVFSQHTVFLGGLDPFLDKLSDLKKLAPEQKILVEADSAVEALRIAAAGADVVQVDKMPVAELAALVSEIRSRFPGVAV
SAAGGINGENAAAYAATGIDIIVLSSVYFGKPADISTSILPVKSN

Sequences:

>Translated_285_residues
MYSLTPDSEIERYIEEDVPYGDLTTTLLGIGDEPGEITFTTRDRTVLCCTEEAGRVLAKCGAEVLSMLPSGTIAAPGTEI
LRASGPAAALHAGWKVAMNLLEYASGISTRTATIVERARAANPGINVVTTRKSFPGTKKIAMKAIMAGGAFPHRLGLSES
ILVFSQHTVFLGGLDPFLDKLSDLKKLAPEQKILVEADSAVEALRIAAAGADVVQVDKMPVAELAALVSEIRSRFPGVAV
SAAGGINGENAAAYAATGIDIIVLSSVYFGKPADISTSILPVKSN
>Mature_285_residues
MYSLTPDSEIERYIEEDVPYGDLTTTLLGIGDEPGEITFTTRDRTVLCCTEEAGRVLAKCGAEVLSMLPSGTIAAPGTEI
LRASGPAAALHAGWKVAMNLLEYASGISTRTATIVERARAANPGINVVTTRKSFPGTKKIAMKAIMAGGAFPHRLGLSES
ILVFSQHTVFLGGLDPFLDKLSDLKKLAPEQKILVEADSAVEALRIAAAGADVVQVDKMPVAELAALVSEIRSRFPGVAV
SAAGGINGENAAAYAATGIDIIVLSSVYFGKPADISTSILPVKSN

Specific function: NAD biosynthesis; aspartate to NaMN; third (last) step. [C]

COG id: COG0157

COG function: function code H; Nicotinate-nucleotide pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadC/modD family [H]

Homologues:

Organism=Homo sapiens, GI45269149, Length=272, Percent_Identity=29.7794117647059, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1786299, Length=228, Percent_Identity=25.4385964912281, Blast_Score=83, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321162, Length=274, Percent_Identity=25.1824817518248, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR006242
- InterPro:   IPR002638
- InterPro:   IPR022412 [H]

Pfam domain/function: PF01729 QRPTase_C; PF02749 QRPTase_N [H]

EC number: 2.4.2.-

Molecular weight: Translated: 29774; Mature: 29774

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSLTPDSEIERYIEEDVPYGDLTTTLLGIGDEPGEITFTTRDRTVLCCTEEAGRVLAKC
CCCCCCHHHHHHHHHHCCCCCCHHHHHEECCCCCCEEEEEECCCEEEEECHHHHHHHHHH
GAEVLSMLPSGTIAAPGTEILRASGPAAALHAGWKVAMNLLEYASGISTRTATIVERARA
HHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
ANPGINVVTTRKSFPGTKKIAMKAIMAGGAFPHRLGLSESILVFSQHTVFLGGLDPFLDK
CCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCHHCCCCCEEEEEEECEEEECCHHHHHHH
LSDLKKLAPEQKILVEADSAVEALRIAAAGADVVQVDKMPVAELAALVSEIRSRFPGVAV
HHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCEEE
SAAGGINGENAAAYAATGIDIIVLSSVYFGKPADISTSILPVKSN
EECCCCCCCCCEEEEECCCEEEEEEHHHCCCCCCCCCEEEEECCC
>Mature Secondary Structure
MYSLTPDSEIERYIEEDVPYGDLTTTLLGIGDEPGEITFTTRDRTVLCCTEEAGRVLAKC
CCCCCCHHHHHHHHHHCCCCCCHHHHHEECCCCCCEEEEEECCCEEEEECHHHHHHHHHH
GAEVLSMLPSGTIAAPGTEILRASGPAAALHAGWKVAMNLLEYASGISTRTATIVERARA
HHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
ANPGINVVTTRKSFPGTKKIAMKAIMAGGAFPHRLGLSESILVFSQHTVFLGGLDPFLDK
CCCCCEEEEECCCCCCHHHHHHHHHHHCCCCCHHCCCCCEEEEEEECEEEECCHHHHHHH
LSDLKKLAPEQKILVEADSAVEALRIAAAGADVVQVDKMPVAELAALVSEIRSRFPGVAV
HHHHHHHCCCCEEEEECHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHHHHCCCEEE
SAAGGINGENAAAYAATGIDIIVLSSVYFGKPADISTSILPVKSN
EECCCCCCCCCEEEEECCCEEEEEEHHHCCCCCCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]