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The map label for this gene is xanB [H]

Identifier: 21673148

GI number: 21673148

Start: 322951

End: 324363

Strand: Direct

Name: xanB [H]

Synonym: CT0309

Alternate gene names: 21673148

Gene position: 322951-324363 (Clockwise)

Preceding gene: 21673147

Following gene: 21673149

Centisome position: 14.99

GC content: 59.24

Gene sequence:

>1413_bases
ATGATGATCATGCCTGTCATTCTTTCCGGCGGTTCCGGAACGAGGCTCTGGCCGCTTTCGAGGGCGATGTATCCGAAGCA
GCTTTTGCCGCTCTTCGGCGAAAAAACCATGCTTCAGGATACGGTGCTCCGGGTCGGGTCGATTGAGGGTGTCGGGCCGG
TCATCTGCGTCTGCAATGATGAGCACCGCTTTCTGGTTGCCGAGCAACTCCGACAGATCGGGGTGGCCGAGCAGGCGATC
ATTCTGGAGCCTTTCGGGCGCAATACGGCGCCAGCTGCCGCTATTGCAGCGCTGGTCATTGCTGCGACCCATCCCGGCGC
GCTCATGCTGCTTCTGCCTGCTGATCACGTTATTCTCGACAGGCAAGGCTTTGTTGCCTCGATTGAATCGGCACGGAGCG
CGGCTGAGTCCGGCAGTCTGGTGACTTTCGGCATCGTACCGTCCACGCCTGAAACGAGGTATGGCTATATCCGGGCGGTT
GCCGGTTCTACGGGAGTGACCCGTCCTGTCGCTGAATTCGTCGAGAAACCATCCCTTGAGCGGGCGGAAGGCTACGTGGT
TTCAGGCGACTATTTCTGGAACAGCGGCATGTTCCTGTTCCGTCCAGAAATCTATCTCGCTGAGCTTGAAGCTTCCTCGC
CTGAAATACTCGACGCATGCCGCAAATCCCTCGAAAATGCCCGGCGTGATCTCGACTTTCTGAGGCTCGATCCTGAGGCC
TTTGCAGCCTGTCCCGCAAATTCGATCGACTATGCCGTCATGGAAAAAACTTCCAACGCAGTGGTTGTGCCCATGCAGGC
AGGCTGGCGCGATGTTGGTGCGTGGTCGGCACTTTGGGAGGCCCAGGAACGCGATGCCGAGGGCAACATCAAACGTGGTG
ATGTGCTGACGCACGGAGTCCGGAACAGCTACATCCACGCCACCAGCCGGCTAGTGGCGGCAGTCGGCCTCGAAGAGCAC
GTGATCGTCGAAACCGCCGACGCGGTGCTGGTTGCTTCAAAAGAGCGGGTGCAGGAGGTCAAAGCCATCGTTGAGCAACT
GAAGTTGCAGAAGCGCGAAGAGCCGCTGATCCACCGGCGGGTTTACCGGCCATGGGGTTCATACGAAACCGTCGATGAGG
GCGAACGCTTCAAGGTCAAGCGCATTACGGTCAAGCCGGGCGCGGCGCTTTCTTTGCAGATGCACAGCAGGCGCGCTGAG
CACTGGATCGTGGTGACTGGCAGGGCGCTGGTGACGGTCGGGAAAAAACAGGTGCCGCTGGAGGCGAACCAGTCGATCTA
CATTCCGGTCGAAGAGCTTCACCGGCTCGAAAATCCCGGCGACGAGCCGCTCGAACTCATTGAAGTGCAGTCGGGCGGTT
ACCTCGGCGAGGACGACATCGTTCGCTTTGAAGATCACTACGGCCGACTGTGA

Upstream 100 bases:

>100_bases
TACGTCGGGAGCCTATCAGCACTATTATGAAAAGATGTACGCTGGCCGCTGAGTGTGGTTGTGACGTTCAATTCTCGGTA
ACCATTCCATCGATTTTGCA

Downstream 100 bases:

>100_bases
ACAGTGGACGGAGTTGCCTTTCCGGTTTTTTCTTCTCTTTAGGATTTATAGGTTGTATAAGTTTTATCGGGTCTGTAAGT
CCCATAGAAGAGGATGGATG

Product: mannose-6-phosphate isomerase/mannose-1-phosphate guanylyl transferase

Products: NA

Alternate protein names: Mannose-6-phosphate isomerase; Phosphohexomutase; Phosphomannose isomerase; PMI; Mannose-1-phosphate guanylyl transferase; GDP-mannose pyrophosphorylase; GMP; GMPP [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MMIMPVILSGGSGTRLWPLSRAMYPKQLLPLFGEKTMLQDTVLRVGSIEGVGPVICVCNDEHRFLVAEQLRQIGVAEQAI
ILEPFGRNTAPAAAIAALVIAATHPGALMLLLPADHVILDRQGFVASIESARSAAESGSLVTFGIVPSTPETRYGYIRAV
AGSTGVTRPVAEFVEKPSLERAEGYVVSGDYFWNSGMFLFRPEIYLAELEASSPEILDACRKSLENARRDLDFLRLDPEA
FAACPANSIDYAVMEKTSNAVVVPMQAGWRDVGAWSALWEAQERDAEGNIKRGDVLTHGVRNSYIHATSRLVAAVGLEEH
VIVETADAVLVASKERVQEVKAIVEQLKLQKREEPLIHRRVYRPWGSYETVDEGERFKVKRITVKPGAALSLQMHSRRAE
HWIVVTGRALVTVGKKQVPLEANQSIYIPVEELHRLENPGDEPLELIEVQSGGYLGEDDIVRFEDHYGRL

Sequences:

>Translated_470_residues
MMIMPVILSGGSGTRLWPLSRAMYPKQLLPLFGEKTMLQDTVLRVGSIEGVGPVICVCNDEHRFLVAEQLRQIGVAEQAI
ILEPFGRNTAPAAAIAALVIAATHPGALMLLLPADHVILDRQGFVASIESARSAAESGSLVTFGIVPSTPETRYGYIRAV
AGSTGVTRPVAEFVEKPSLERAEGYVVSGDYFWNSGMFLFRPEIYLAELEASSPEILDACRKSLENARRDLDFLRLDPEA
FAACPANSIDYAVMEKTSNAVVVPMQAGWRDVGAWSALWEAQERDAEGNIKRGDVLTHGVRNSYIHATSRLVAAVGLEEH
VIVETADAVLVASKERVQEVKAIVEQLKLQKREEPLIHRRVYRPWGSYETVDEGERFKVKRITVKPGAALSLQMHSRRAE
HWIVVTGRALVTVGKKQVPLEANQSIYIPVEELHRLENPGDEPLELIEVQSGGYLGEDDIVRFEDHYGRL
>Mature_470_residues
MMIMPVILSGGSGTRLWPLSRAMYPKQLLPLFGEKTMLQDTVLRVGSIEGVGPVICVCNDEHRFLVAEQLRQIGVAEQAI
ILEPFGRNTAPAAAIAALVIAATHPGALMLLLPADHVILDRQGFVASIESARSAAESGSLVTFGIVPSTPETRYGYIRAV
AGSTGVTRPVAEFVEKPSLERAEGYVVSGDYFWNSGMFLFRPEIYLAELEASSPEILDACRKSLENARRDLDFLRLDPEA
FAACPANSIDYAVMEKTSNAVVVPMQAGWRDVGAWSALWEAQERDAEGNIKRGDVLTHGVRNSYIHATSRLVAAVGLEEH
VIVETADAVLVASKERVQEVKAIVEQLKLQKREEPLIHRRVYRPWGSYETVDEGERFKVKRITVKPGAALSLQMHSRRAE
HWIVVTGRALVTVGKKQVPLEANQSIYIPVEELHRLENPGDEPLELIEVQSGGYLGEDDIVRFEDHYGRL

Specific function: Involved in xanthan production [H]

COG id: COG0836

COG function: function code M; Mannose-1-phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannose-6-phosphate isomerase type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788362, Length=474, Percent_Identity=56.7510548523207, Blast_Score=535, Evalue=1e-153,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR006375
- InterPro:   IPR001538
- InterPro:   IPR005835
- InterPro:   IPR014710 [H]

Pfam domain/function: PF01050 MannoseP_isomer; PF00483 NTP_transferase [H]

EC number: =5.3.1.8; =2.7.7.13 [H]

Molecular weight: Translated: 51882; Mature: 51882

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMIMPVILSGGSGTRLWPLSRAMYPKQLLPLFGEKTMLQDTVLRVGSIEGVGPVICVCND
CEEEEEEEECCCCCEEEECHHHCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEECC
EHRFLVAEQLRQIGVAEQAIILEPFGRNTAPAAAIAALVIAATHPGALMLLLPADHVILD
CCCCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHEECCCCEEEEEECCCEEEEE
RQGFVASIESARSAAESGSLVTFGIVPSTPETRYGYIRAVAGSTGVTRPVAEFVEKPSLE
CCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCH
RAEGYVVSGDYFWNSGMFLFRPEIYLAELEASSPEILDACRKSLENARRDLDFLRLDPEA
HHCCEEEECCEEECCCEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEECHHH
FAACPANSIDYAVMEKTSNAVVVPMQAGWRDVGAWSALWEAQERDAEGNIKRGDVLTHGV
HHCCCCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCC
RNSYIHATSRLVAAVGLEEHVIVETADAVLVASKERVQEVKAIVEQLKLQKREEPLIHRR
CCCHHHHHHHHHHHCCCCCEEEEEECCEEEEECHHHHHHHHHHHHHHHHHHHCCCHHHHH
VYRPWGSYETVDEGERFKVKRITVKPGAALSLQMHSRRAEHWIVVTGRALVTVGKKQVPL
HCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCCCEEEEEECCEEEEECCCCCCC
EANQSIYIPVEELHRLENPGDEPLELIEVQSGGYLGEDDIVRFEDHYGRL
CCCCEEEEEHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCC
>Mature Secondary Structure
MMIMPVILSGGSGTRLWPLSRAMYPKQLLPLFGEKTMLQDTVLRVGSIEGVGPVICVCND
CEEEEEEEECCCCCEEEECHHHCCHHHHHHHHCCHHHHHHHHHHHCCCCCCCCEEEEECC
EHRFLVAEQLRQIGVAEQAIILEPFGRNTAPAAAIAALVIAATHPGALMLLLPADHVILD
CCCCHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHHHHEECCCCEEEEEECCCEEEEE
RQGFVASIESARSAAESGSLVTFGIVPSTPETRYGYIRAVAGSTGVTRPVAEFVEKPSLE
CCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCH
RAEGYVVSGDYFWNSGMFLFRPEIYLAELEASSPEILDACRKSLENARRDLDFLRLDPEA
HHCCEEEECCEEECCCEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEECHHH
FAACPANSIDYAVMEKTSNAVVVPMQAGWRDVGAWSALWEAQERDAEGNIKRGDVLTHGV
HHCCCCCCCCEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHCCC
RNSYIHATSRLVAAVGLEEHVIVETADAVLVASKERVQEVKAIVEQLKLQKREEPLIHRR
CCCHHHHHHHHHHHCCCCCEEEEEECCEEEEECHHHHHHHHHHHHHHHHHHHCCCHHHHH
VYRPWGSYETVDEGERFKVKRITVKPGAALSLQMHSRRAEHWIVVTGRALVTVGKKQVPL
HCCCCCCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCCCEEEEEECCEEEEECCCCCCC
EANQSIYIPVEELHRLENPGDEPLELIEVQSGGYLGEDDIVRFEDHYGRL
CCCCEEEEEHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1370280; 11589581 [H]