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The map label for this gene is idsA [H]

Identifier: 21673095

GI number: 21673095

Start: 264669

End: 265667

Strand: Reverse

Name: idsA [H]

Synonym: CT0256

Alternate gene names: 21673095

Gene position: 265667-264669 (Counterclockwise)

Preceding gene: 21673096

Following gene: 21673094

Centisome position: 12.33

GC content: 58.86

Gene sequence:

>999_bases
ATGTCCTCACCGATTACCCAAGCACAGGTTGAAAGCAAGTACCGGCAATACCATGCAAAGATCAACGAAGCGCTTGCCGC
CTGCTTTCCGAAAGAGAAGCCGGCAACCCTTTACGACCCTGCGCGCTACATTCTCGAAGGAAAGGGTAAGCGAATCCGTC
CGTTCCTGACTTTGCTTGCCGCCGAAGCGGTCAGCGGCAAGTCCGACAACGCGCTTGGCGTTGCCCTCGGTATCGAGGTG
CTGCACAACTTCACCCTGATGCACGACGACATCATGGACCAGGCCGATCTGCGCCATGGCCGTCCCACCGTGCACAAGCA
GTGGAATGTCAACGCGGCGATTCTTTCGGGTGACATGATGATCGCCTACGCCTACGAGCTGGCACTCAAGGCGATCAGTT
CGCGCCACGCCGAAATAATCCACATCTTCAACGATGCCAACATCACGATCTGCGAAGGGCAGGCGCTCGACATGGAGCTC
GAACAGCGCAAGGATGTCACCATCGCCGACTACCTCGACATGATCTCCAAAAAGACGGGGCGACTCATCTCGGCGGCGCT
CGAAGCGGGCGGCGTTGCGGGCGACGGCACGCCGGAGCAGATCGCAGCGTTGGTCACCTTCGGCGAAAAGATCGGACGAG
CTTTCCAGATTCAGGATGACTATCTCGACATCATGGCCGGAGACGGCAAGTCGGGCAAGGTGCCGGGCGGCGACGTCATC
AACGGCAAAAAGACCTGGCTGCTGCTCCGTTCGCTCGAACTGGCCGAAGGCGCTGACCGCGAGCTTTTACAATCGATCTT
CGACAACAACGGCACCTCGCCCGACAACGTCCCAGCGGTCAAGGCGATCTTCGAGAAGTGCGGTGTGCTCAACGAGACCA
GGGCGAAAATCAACGAGGATACCGAAGCAGCGCTGGCAGCGCTCGACGCCCTTCCGTTCGAGGAGGGACGCGGCTATCTG
AGAGGCTTTGCCAACATTCTCATGAAGCGCGATTTCTGA

Upstream 100 bases:

>100_bases
GGGCAAACGATCTTCGGGCGGCCATGTTCCTGACCGGATCGGCCACCATCGAACAGCTTAAACACGCACGAATCTACCGT
AAACCCTGACGACAGCAGTC

Downstream 100 bases:

>100_bases
GCTTGTTCCGGGGGGTCGCCCCTCCCCCCGAACGCTCTTCAACTCCCCTGCCCCCAACCATGACCACAACCCCTGAGCCA
GGCGCAGCGCTTTTGCTGCT

Product: isoprenyl synthetase

Products: NA

Alternate protein names: (2E,6E)-farnesyl diphosphate synthase; Dimethylallyltranstransferase; Farnesyl diphosphate synthase; Farnesyl pyrophosphate synthase; FPP synthase; Geranyltranstransferase [H]

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MSSPITQAQVESKYRQYHAKINEALAACFPKEKPATLYDPARYILEGKGKRIRPFLTLLAAEAVSGKSDNALGVALGIEV
LHNFTLMHDDIMDQADLRHGRPTVHKQWNVNAAILSGDMMIAYAYELALKAISSRHAEIIHIFNDANITICEGQALDMEL
EQRKDVTIADYLDMISKKTGRLISAALEAGGVAGDGTPEQIAALVTFGEKIGRAFQIQDDYLDIMAGDGKSGKVPGGDVI
NGKKTWLLLRSLELAEGADRELLQSIFDNNGTSPDNVPAVKAIFEKCGVLNETRAKINEDTEAALAALDALPFEEGRGYL
RGFANILMKRDF

Sequences:

>Translated_332_residues
MSSPITQAQVESKYRQYHAKINEALAACFPKEKPATLYDPARYILEGKGKRIRPFLTLLAAEAVSGKSDNALGVALGIEV
LHNFTLMHDDIMDQADLRHGRPTVHKQWNVNAAILSGDMMIAYAYELALKAISSRHAEIIHIFNDANITICEGQALDMEL
EQRKDVTIADYLDMISKKTGRLISAALEAGGVAGDGTPEQIAALVTFGEKIGRAFQIQDDYLDIMAGDGKSGKVPGGDVI
NGKKTWLLLRSLELAEGADRELLQSIFDNNGTSPDNVPAVKAIFEKCGVLNETRAKINEDTEAALAALDALPFEEGRGYL
RGFANILMKRDF
>Mature_331_residues
SSPITQAQVESKYRQYHAKINEALAACFPKEKPATLYDPARYILEGKGKRIRPFLTLLAAEAVSGKSDNALGVALGIEVL
HNFTLMHDDIMDQADLRHGRPTVHKQWNVNAAILSGDMMIAYAYELALKAISSRHAEIIHIFNDANITICEGQALDMELE
QRKDVTIADYLDMISKKTGRLISAALEAGGVAGDGTPEQIAALVTFGEKIGRAFQIQDDYLDIMAGDGKSGKVPGGDVIN
GKKTWLLLRSLELAEGADRELLQSIFDNNGTSPDNVPAVKAIFEKCGVLNETRAKINEDTEAALAALDALPFEEGRGYLR
GFANILMKRDF

Specific function: Supplies Octaprenyl Diphosphate, The Precursor For The Side Chain Of The Isoprenoid Quinones Ubiquinone And Menaquinone. [C]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=216, Percent_Identity=30.5555555555556, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI4758430, Length=276, Percent_Identity=25, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI83700220, Length=276, Percent_Identity=25, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI209571582, Length=254, Percent_Identity=28.740157480315, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI4503685, Length=254, Percent_Identity=28.740157480315, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI209571584, Length=253, Percent_Identity=28.8537549407115, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789578, Length=289, Percent_Identity=32.5259515570934, Blast_Score=154, Evalue=6e-39,
Organism=Escherichia coli, GI1786623, Length=227, Percent_Identity=37.4449339207048, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17505681, Length=301, Percent_Identity=23.2558139534884, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17508563, Length=274, Percent_Identity=24.8175182481752, Blast_Score=68, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6325188, Length=245, Percent_Identity=28.1632653061224, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6322294, Length=275, Percent_Identity=25.8181818181818, Blast_Score=73, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24651612, Length=301, Percent_Identity=25.9136212624585, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI17137582, Length=274, Percent_Identity=27.7372262773723, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI281365769, Length=290, Percent_Identity=24.4827586206897, Blast_Score=68, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24660002, Length=290, Percent_Identity=24.4827586206897, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.1; =2.5.1.10 [H]

Molecular weight: Translated: 36264; Mature: 36133

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPITQAQVESKYRQYHAKINEALAACFPKEKPATLYDPARYILEGKGKRIRPFLTLLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCHHHHHHCCCCCHHHHHHHHHH
AEAVSGKSDNALGVALGIEVLHNFTLMHDDIMDQADLRHGRPTVHKQWNVNAAILSGDMM
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCH
IAYAYELALKAISSRHAEIIHIFNDANITICEGQALDMELEQRKDVTIADYLDMISKKTG
HHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHH
RLISAALEAGGVAGDGTPEQIAALVTFGEKIGRAFQIQDDYLDIMAGDGKSGKVPGGDVI
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCCCCCCC
NGKKTWLLLRSLELAEGADRELLQSIFDNNGTSPDNVPAVKAIFEKCGVLNETRAKINED
CCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCC
TEAALAALDALPFEEGRGYLRGFANILMKRDF
HHHHHHHHHCCCCHHCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SSPITQAQVESKYRQYHAKINEALAACFPKEKPATLYDPARYILEGKGKRIRPFLTLLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCHHHHHHCCCCCHHHHHHHHHH
AEAVSGKSDNALGVALGIEVLHNFTLMHDDIMDQADLRHGRPTVHKQWNVNAAILSGDMM
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCH
IAYAYELALKAISSRHAEIIHIFNDANITICEGQALDMELEQRKDVTIADYLDMISKKTG
HHHHHHHHHHHHHCCCCEEEEEEECCCEEEECCCCCCCHHHHCCCCHHHHHHHHHHHHHH
RLISAALEAGGVAGDGTPEQIAALVTFGEKIGRAFQIQDDYLDIMAGDGKSGKVPGGDVI
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCEEEECCCCEEEEECCCCCCCCCCCCCC
NGKKTWLLLRSLELAEGADRELLQSIFDNNGTSPDNVPAVKAIFEKCGVLNETRAKINED
CCCHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCC
TEAALAALDALPFEEGRGYLRGFANILMKRDF
HHHHHHHHHCCCCHHCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]