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The map label for this gene is surA [H]

Identifier: 21673044

GI number: 21673044

Start: 214100

End: 216202

Strand: Direct

Name: surA [H]

Synonym: CT0203

Alternate gene names: 21673044

Gene position: 214100-216202 (Clockwise)

Preceding gene: 21673043

Following gene: 21673051

Centisome position: 9.94

GC content: 58.2

Gene sequence:

>2103_bases
ATGGCACTAATGAGCAAGTTGAGGGATAAAACGCACATCGTGTTGTTTGTCCTCGTGGCGGCGTTCCTTGCCCTGATCGT
TTTCGAGTGGGGGATGAACTTCACCGGCCCCACCAGAAAAGCGGGCGTAGCCGGGAAGGTCAATGGCGAGTCGATCTCCA
TGAATGAATACGAAGCGTTGTACAACAACATTGTCGCCGGGTTCCGGCAGAGCAATCCAGGCGTAGAAATCACCTCCGGC
CTCGACGCGAAGTTTCGCGAGCAGGCCTGGAACTATGTTGTCGATCAGACGCTTCTTGCCCAGCTTCTCAAGAAATATGG
CATCACCGTCACCGACCAGGAGGTGCTCGACGCGGTCAATAATCCCGTCAATCCGCCAGCGATCATTCGCCAGAACTTCA
CCGATCCCAGGACTGGCAAGATCGACCGCCAGTTGCTTGAACAGGCGCGTAGCGATCCGAAAGCCAAAGATTTCTGGCTC
AACGCCCAGGAGGCGATCAAGCGCGAACTGATGGTCAACAAGCTGGTTATGACACTGAGGACCATGGTTTTCGTTACCGA
TCCCGAGCTTACTGAAGTGGTGCAGCGCCAGTTCACCACCTTTGCCGGTTCGTTTATTCCCTTTCCGTACAGCTATGCGG
GCGCGGAAACCAATTTTCCGGTCAAAGATGACGAGATCAAGGCCTGGTACGACTCTCACAAGGAGCAGTTCCGGGAGGAG
CCGGTGCGTAGCGCTGAGTTTGTCTTTTTCCCGTTGACTCCCTCCAGGCAGGATAGCCTTCAGGTTAAAAAGGAGATCGA
CGGGCTGATTCCGCAGTTCGCTGCGGCAAAGAGCGACAGCGAGTTCGTCAAGATTCAGAGCGACCTGCCGAATTCGGCGA
ATGTTACGCTTTCAAGAGCGGACTTTTCGCCCGCCGCAGGGCAGGCGCTGTTCAGCTCGCCGAAGCTCGTGCCCGGCCAG
ATTGTCGGCCCCATCGCCGACGAGGGCTACTACCGCTTGCTCAAGATTAAGAGCGTCACGACCGGCGAACCGGTTGCGAG
CGCCTCGCACATTCTGATTCGCCTTAATCCGGCGGACAAGGCCGAGGCCGCGCGCGCCATGGGCCTGCTCAAAAAGATTT
CCGAGGAGCTGAAGGGAGGCGCGTCATTCGCCTCGCTGGCCGCTAAATATTCCGAGGATCCCGGCAGCGCCCGCAACGGC
GGTTTTGTTGGCTGGTTCACCAAGGATCGCATGGTGCCCCAGTTCGCCCAGGCGGTCTTTGCCGGCAAGCCCGGTCAGAT
CGTCGGGCCGGTGCAGACCCAGTTCGGCCTGCATATCATCAAGATCGAAGGGTTTGACAACCGGCGCATCGTCTGCTCGG
AGGTCGCCCGCCAGATCAAGGCATCGACGCAGACCTCCGAAACGATCAAGCGTCAAGCGCAGGCTTTCCTGACCGAGGCA
AAGTCGAAGGGATTTGAAGCGGCGGCGAAGGCGCAGAGGCTCGAAGTGGGCAAAACCGGCGACTTTACGCGCCAGAGCCT
GCTCGCCGTGCCGGGCATGGGCGAGGCGATTACTGGCTTCGCATTCAAGGCCAAAGATAGTGATATTTCCGACGTGCTCG
ATGCCGAGAAGGGATTCGTGGTCGCGAAGTTGTTGACGCAAAACGATACCGGTTATCACCAGCTCGACGCCCAGCTCAAG
GAGATGATCAAAACCGAACTGGTTCGTGAAAAACAGGGCGCGGCGCTGAAATCGAAGCTTGTCGCTTTGTCGAAAAGCTC
CGGCGGCTCGCTCGACGCCATCGCCGCAAAGGACCCGTCTCTGCGTAAAATCACCTCGAAGGAGATTCGCTGGCGCGACG
GCTACATCGACGGGTACGGCGTCGATCCCCAGCTCGTGGAGGGAATGGCGGGCATGAAGCTCAACACGCTTTCGCAGCCG
GTACAGACCAGCGGAGGATATGCGCTCGTGCAACTGACCAGCCGCCAGCTTGCACCGGGCACCGATCTTGCCGCCGAGAA
ACAGAAGGTTTTGCCGCAACTGATGCAGGCCAGGCAGCAGCAGTTCCTTTCCGAGTATCTGCAATCGTATCGCCGGAACG
CCAAAATCGAGGATTTCAGGTAG

Upstream 100 bases:

>100_bases
AGCATGAGATTTTTCACAACTTCGCCTTCGTGCCGCTCTGCGGGCGTGAAGGTTGGGCAGACAACAACGAATAAACAGTC
AAAGACAGAAAAGAGAAGTT

Downstream 100 bases:

>100_bases
CGCCATTCAGGCAGACCCGATGCCGGAACAGCAAAAAGCCGCCCGGATAATTCCGAGGCGGCTTTTTTGTTATCGAGCTC
TTACGGTCTTGCGTGTGATA

Product: peptidyl-prolyl cis-trans isomerase, PpiC-type

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 700; Mature: 699

Protein sequence:

>700_residues
MALMSKLRDKTHIVLFVLVAAFLALIVFEWGMNFTGPTRKAGVAGKVNGESISMNEYEALYNNIVAGFRQSNPGVEITSG
LDAKFREQAWNYVVDQTLLAQLLKKYGITVTDQEVLDAVNNPVNPPAIIRQNFTDPRTGKIDRQLLEQARSDPKAKDFWL
NAQEAIKRELMVNKLVMTLRTMVFVTDPELTEVVQRQFTTFAGSFIPFPYSYAGAETNFPVKDDEIKAWYDSHKEQFREE
PVRSAEFVFFPLTPSRQDSLQVKKEIDGLIPQFAAAKSDSEFVKIQSDLPNSANVTLSRADFSPAAGQALFSSPKLVPGQ
IVGPIADEGYYRLLKIKSVTTGEPVASASHILIRLNPADKAEAARAMGLLKKISEELKGGASFASLAAKYSEDPGSARNG
GFVGWFTKDRMVPQFAQAVFAGKPGQIVGPVQTQFGLHIIKIEGFDNRRIVCSEVARQIKASTQTSETIKRQAQAFLTEA
KSKGFEAAAKAQRLEVGKTGDFTRQSLLAVPGMGEAITGFAFKAKDSDISDVLDAEKGFVVAKLLTQNDTGYHQLDAQLK
EMIKTELVREKQGAALKSKLVALSKSSGGSLDAIAAKDPSLRKITSKEIRWRDGYIDGYGVDPQLVEGMAGMKLNTLSQP
VQTSGGYALVQLTSRQLAPGTDLAAEKQKVLPQLMQARQQQFLSEYLQSYRRNAKIEDFR

Sequences:

>Translated_700_residues
MALMSKLRDKTHIVLFVLVAAFLALIVFEWGMNFTGPTRKAGVAGKVNGESISMNEYEALYNNIVAGFRQSNPGVEITSG
LDAKFREQAWNYVVDQTLLAQLLKKYGITVTDQEVLDAVNNPVNPPAIIRQNFTDPRTGKIDRQLLEQARSDPKAKDFWL
NAQEAIKRELMVNKLVMTLRTMVFVTDPELTEVVQRQFTTFAGSFIPFPYSYAGAETNFPVKDDEIKAWYDSHKEQFREE
PVRSAEFVFFPLTPSRQDSLQVKKEIDGLIPQFAAAKSDSEFVKIQSDLPNSANVTLSRADFSPAAGQALFSSPKLVPGQ
IVGPIADEGYYRLLKIKSVTTGEPVASASHILIRLNPADKAEAARAMGLLKKISEELKGGASFASLAAKYSEDPGSARNG
GFVGWFTKDRMVPQFAQAVFAGKPGQIVGPVQTQFGLHIIKIEGFDNRRIVCSEVARQIKASTQTSETIKRQAQAFLTEA
KSKGFEAAAKAQRLEVGKTGDFTRQSLLAVPGMGEAITGFAFKAKDSDISDVLDAEKGFVVAKLLTQNDTGYHQLDAQLK
EMIKTELVREKQGAALKSKLVALSKSSGGSLDAIAAKDPSLRKITSKEIRWRDGYIDGYGVDPQLVEGMAGMKLNTLSQP
VQTSGGYALVQLTSRQLAPGTDLAAEKQKVLPQLMQARQQQFLSEYLQSYRRNAKIEDFR
>Mature_699_residues
ALMSKLRDKTHIVLFVLVAAFLALIVFEWGMNFTGPTRKAGVAGKVNGESISMNEYEALYNNIVAGFRQSNPGVEITSGL
DAKFREQAWNYVVDQTLLAQLLKKYGITVTDQEVLDAVNNPVNPPAIIRQNFTDPRTGKIDRQLLEQARSDPKAKDFWLN
AQEAIKRELMVNKLVMTLRTMVFVTDPELTEVVQRQFTTFAGSFIPFPYSYAGAETNFPVKDDEIKAWYDSHKEQFREEP
VRSAEFVFFPLTPSRQDSLQVKKEIDGLIPQFAAAKSDSEFVKIQSDLPNSANVTLSRADFSPAAGQALFSSPKLVPGQI
VGPIADEGYYRLLKIKSVTTGEPVASASHILIRLNPADKAEAARAMGLLKKISEELKGGASFASLAAKYSEDPGSARNGG
FVGWFTKDRMVPQFAQAVFAGKPGQIVGPVQTQFGLHIIKIEGFDNRRIVCSEVARQIKASTQTSETIKRQAQAFLTEAK
SKGFEAAAKAQRLEVGKTGDFTRQSLLAVPGMGEAITGFAFKAKDSDISDVLDAEKGFVVAKLLTQNDTGYHQLDAQLKE
MIKTELVREKQGAALKSKLVALSKSSGGSLDAIAAKDPSLRKITSKEIRWRDGYIDGYGVDPQLVEGMAGMKLNTLSQPV
QTSGGYALVQLTSRQLAPGTDLAAEKQKVLPQLMQARQQQFLSEYLQSYRRNAKIEDFR

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=163, Percent_Identity=34.3558282208589, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790211, Length=97, Percent_Identity=41.2371134020619, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 77050; Mature: 76919

Theoretical pI: Translated: 9.61; Mature: 9.61

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALMSKLRDKTHIVLFVLVAAFLALIVFEWGMNFTGPTRKAGVAGKVNGESISMNEYEAL
CCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEECHHHHHHH
YNNIVAGFRQSNPGVEITSGLDAKFREQAWNYVVDQTLLAQLLKKYGITVTDQEVLDAVN
HHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
NPVNPPAIIRQNFTDPRTGKIDRQLLEQARSDPKAKDFWLNAQEAIKRELMVNKLVMTLR
CCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHH
TMVFVTDPELTEVVQRQFTTFAGSFIPFPYSYAGAETNFPVKDDEIKAWYDSHKEQFREE
HHHEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
PVRSAEFVFFPLTPSRQDSLQVKKEIDGLIPQFAAAKSDSEFVKIQSDLPNSANVTLSRA
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEC
DFSPAAGQALFSSPKLVPGQIVGPIADEGYYRLLKIKSVTTGEPVASASHILIRLNPADK
CCCCHHCHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCH
AEAARAMGLLKKISEELKGGASFASLAAKYSEDPGSARNGGFVGWFTKDRMVPQFAQAVF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHH
AGKPGQIVGPVQTQFGLHIIKIEGFDNRRIVCSEVARQIKASTQTSETIKRQAQAFLTEA
CCCCCCEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
KSKGFEAAAKAQRLEVGKTGDFTRQSLLAVPGMGEAITGFAFKAKDSDISDVLDAEKGFV
HHCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHCCEEECCCCCHHHHHHCCCCEE
VAKLLTQNDTGYHQLDAQLKEMIKTELVREKQGAALKSKLVALSKSSGGSLDAIAAKDPS
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCC
LRKITSKEIRWRDGYIDGYGVDPQLVEGMAGMKLNTLSQPVQTSGGYALVQLTSRQLAPG
HHHHHHHHCEECCCCCCCCCCCHHHHHCCCCCEEHHHCCCHHCCCCEEEEEEECCCCCCC
TDLAAEKQKVLPQLMQARQQQFLSEYLQSYRRNAKIEDFR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
ALMSKLRDKTHIVLFVLVAAFLALIVFEWGMNFTGPTRKAGVAGKVNGESISMNEYEAL
CHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEECHHHHHHH
YNNIVAGFRQSNPGVEITSGLDAKFREQAWNYVVDQTLLAQLLKKYGITVTDQEVLDAVN
HHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHC
NPVNPPAIIRQNFTDPRTGKIDRQLLEQARSDPKAKDFWLNAQEAIKRELMVNKLVMTLR
CCCCCCHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHH
TMVFVTDPELTEVVQRQFTTFAGSFIPFPYSYAGAETNFPVKDDEIKAWYDSHKEQFREE
HHHEECCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
PVRSAEFVFFPLTPSRQDSLQVKKEIDGLIPQFAAAKSDSEFVKIQSDLPNSANVTLSRA
CCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCEEEEEC
DFSPAAGQALFSSPKLVPGQIVGPIADEGYYRLLKIKSVTTGEPVASASHILIRLNPADK
CCCCHHCHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEEEEECCCCH
AEAARAMGLLKKISEELKGGASFASLAAKYSEDPGSARNGGFVGWFTKDRMVPQFAQAVF
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCHHHHHHHHH
AGKPGQIVGPVQTQFGLHIIKIEGFDNRRIVCSEVARQIKASTQTSETIKRQAQAFLTEA
CCCCCCEECCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
KSKGFEAAAKAQRLEVGKTGDFTRQSLLAVPGMGEAITGFAFKAKDSDISDVLDAEKGFV
HHCCHHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCHHHCCEEECCCCCHHHHHHCCCCEE
VAKLLTQNDTGYHQLDAQLKEMIKTELVREKQGAALKSKLVALSKSSGGSLDAIAAKDPS
EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCEEEEECCCCC
LRKITSKEIRWRDGYIDGYGVDPQLVEGMAGMKLNTLSQPVQTSGGYALVQLTSRQLAPG
HHHHHHHHCEECCCCCCCCCCCHHHHHCCCCCEEHHHCCCHHCCCCEEEEEEECCCCCCC
TDLAAEKQKVLPQLMQARQQQFLSEYLQSYRRNAKIEDFR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA