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The map label for this gene is ftsY [H]

Identifier: 21673041

GI number: 21673041

Start: 211792

End: 212742

Strand: Direct

Name: ftsY [H]

Synonym: CT0200

Alternate gene names: 21673041

Gene position: 211792-212742 (Clockwise)

Preceding gene: 21673039

Following gene: 21673043

Centisome position: 9.83

GC content: 60.36

Gene sequence:

>951_bases
ATGGGCTTTTTTGACAAGTTAGGGCTGTCGCGCCTCAAGGAGGGGCTCACCAAAACCCGCGACACGCTTCGCGACAAACT
GGCGTTTGTTTCCCGGGGCAAAACCGAGGTGGATGACGAGTTCCTCGAAGAGCTCGAAAACATTCTCGTTGCCGCCGATG
TGGGTGTCGAGACCACGCTTGACATTGTCGATGCGGTCACCGTGCGCTCCAAAGGCAAAACCTACCGTTCGGAGGAGGAG
CTGAACGAGATGGTGATGGGCGAAATTCGCAACCTGCTTGTCGAGTCGGGCCACGAGCATCCGGTTGATTTCGACGCGCC
GTTGTCGGCAAAACCCTACGTCATCATGATCGTCGGCGTCAACGGCGCGGGCAAGACCACCACCGTGGCCAAGCTGGCGC
ACAACTACGACAAGGCGGGCAAGAAGGTGGTGATCGCCGCCGCCGACACCTTCCGCGCCGCGGCCTACGAGCAACTCAAA
ATCTGGGCTGATCGCGCCGGAGTGCCGATCATCGGCCAGGGGCAGGGAGCCGATCCGGCCTCGGTGGTGTTCGACTCGGT
CAGCTCGGCGGTTTCGAAGGGCACGGATGTGGTGCTGGTCGATACGGCGGGCAGGCTGCACAACAAGAGCCACCTGATGG
AGGAGCTGGCCAAAATCATGCGCGTGGCCAAGAAAAAGATCCCCGAAGCGCCGCACGAAGTGCTGCTGGTGCTCGACGGC
ACCACCGGCCAGAACGCCGTACAGCAGGCTCGCGAGTTTACGAAGTTCGTCAACGTCACCGGCCTCGTCATGACCAAACT
CGACGGCACCTCAAAAGGAGGCATCGTGCTTTCGATCTCCCGCGAACTGAACCTGCCGGTCAAGTACATCGGGGTCGGCG
AAAAGATCGACGACCTCCAGCTCTTCGACCGCAAGAGCTTCGTCGAAGCGCTGCTCGAAAAAGAGAAGTGA

Upstream 100 bases:

>100_bases
CGGAAATAGGGTTATATGACATATATTTGCGTACATTGAATTCAATCCGGAATCCGTTCCGATCCCTTCGTCTGTAAACA
TAGCCAATTTCTCATTTTCC

Downstream 100 bases:

>100_bases
AAACGTTCAGCCTTGCCGGATCAGATCAGGCATTGCTTTTTCGAGGCACGGCAACAAGGGTTCCAGCTTGTCAATCCTGA
AAAGATGCGTACCTGCGGCG

Product: signal recognition particle-docking protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MGFFDKLGLSRLKEGLTKTRDTLRDKLAFVSRGKTEVDDEFLEELENILVAADVGVETTLDIVDAVTVRSKGKTYRSEEE
LNEMVMGEIRNLLVESGHEHPVDFDAPLSAKPYVIMIVGVNGAGKTTTVAKLAHNYDKAGKKVVIAAADTFRAAAYEQLK
IWADRAGVPIIGQGQGADPASVVFDSVSSAVSKGTDVVLVDTAGRLHNKSHLMEELAKIMRVAKKKIPEAPHEVLLVLDG
TTGQNAVQQAREFTKFVNVTGLVMTKLDGTSKGGIVLSISRELNLPVKYIGVGEKIDDLQLFDRKSFVEALLEKEK

Sequences:

>Translated_316_residues
MGFFDKLGLSRLKEGLTKTRDTLRDKLAFVSRGKTEVDDEFLEELENILVAADVGVETTLDIVDAVTVRSKGKTYRSEEE
LNEMVMGEIRNLLVESGHEHPVDFDAPLSAKPYVIMIVGVNGAGKTTTVAKLAHNYDKAGKKVVIAAADTFRAAAYEQLK
IWADRAGVPIIGQGQGADPASVVFDSVSSAVSKGTDVVLVDTAGRLHNKSHLMEELAKIMRVAKKKIPEAPHEVLLVLDG
TTGQNAVQQAREFTKFVNVTGLVMTKLDGTSKGGIVLSISRELNLPVKYIGVGEKIDDLQLFDRKSFVEALLEKEK
>Mature_315_residues
GFFDKLGLSRLKEGLTKTRDTLRDKLAFVSRGKTEVDDEFLEELENILVAADVGVETTLDIVDAVTVRSKGKTYRSEEEL
NEMVMGEIRNLLVESGHEHPVDFDAPLSAKPYVIMIVGVNGAGKTTTVAKLAHNYDKAGKKVVIAAADTFRAAAYEQLKI
WADRAGVPIIGQGQGADPASVVFDSVSSAVSKGTDVVLVDTAGRLHNKSHLMEELAKIMRVAKKKIPEAPHEVLLVLDGT
TGQNAVQQAREFTKFVNVTGLVMTKLDGTSKGGIVLSISRELNLPVKYIGVGEKIDDLQLFDRKSFVEALLEKEK

Specific function: Required for normal cell growth and morphogenesis; translocation of at least 1 protein is impaired in its absence [H]

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=281, Percent_Identity=32.3843416370107, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI226371618, Length=206, Percent_Identity=36.8932038834951, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI23308697, Length=302, Percent_Identity=29.8013245033113, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI295424842, Length=302, Percent_Identity=29.8013245033113, Blast_Score=123, Evalue=2e-28,
Organism=Homo sapiens, GI89061728, Length=135, Percent_Identity=31.8518518518519, Blast_Score=82, Evalue=6e-16,
Organism=Escherichia coli, GI1789874, Length=317, Percent_Identity=48.2649842271293, Blast_Score=282, Evalue=3e-77,
Organism=Escherichia coli, GI1788963, Length=291, Percent_Identity=33.6769759450172, Blast_Score=142, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17539958, Length=206, Percent_Identity=38.3495145631068, Blast_Score=153, Evalue=9e-38,
Organism=Caenorhabditis elegans, GI193206261, Length=298, Percent_Identity=31.5436241610738, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6325345, Length=206, Percent_Identity=39.8058252427184, Blast_Score=156, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6320498, Length=232, Percent_Identity=28.8793103448276, Blast_Score=93, Evalue=5e-20,
Organism=Drosophila melanogaster, GI17647949, Length=206, Percent_Identity=38.8349514563107, Blast_Score=150, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24641198, Length=306, Percent_Identity=27.4509803921569, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 34393; Mature: 34262

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFFDKLGLSRLKEGLTKTRDTLRDKLAFVSRGKTEVDDEFLEELENILVAADVGVETTL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEECCCCHHHH
DIVDAVTVRSKGKTYRSEEELNEMVMGEIRNLLVESGHEHPVDFDAPLSAKPYVIMIVGV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEE
NGAGKTTTVAKLAHNYDKAGKKVVIAAADTFRAAAYEQLKIWADRAGVPIIGQGQGADPA
CCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEECCCCCCHH
SVVFDSVSSAVSKGTDVVLVDTAGRLHNKSHLMEELAKIMRVAKKKIPEAPHEVLLVLDG
HHHHHHHHHHHHCCCCEEEEECCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
TTGQNAVQQAREFTKFVNVTGLVMTKLDGTSKGGIVLSISRELNLPVKYIGVGEKIDDLQ
CCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEECCCCCCEEEEECCCCCHHHH
LFDRKSFVEALLEKEK
HHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GFFDKLGLSRLKEGLTKTRDTLRDKLAFVSRGKTEVDDEFLEELENILVAADVGVETTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHEEEECCCCHHHH
DIVDAVTVRSKGKTYRSEEELNEMVMGEIRNLLVESGHEHPVDFDAPLSAKPYVIMIVGV
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEEE
NGAGKTTTVAKLAHNYDKAGKKVVIAAADTFRAAAYEQLKIWADRAGVPIIGQGQGADPA
CCCCCHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCEEECCCCCCHH
SVVFDSVSSAVSKGTDVVLVDTAGRLHNKSHLMEELAKIMRVAKKKIPEAPHEVLLVLDG
HHHHHHHHHHHHCCCCEEEEECCCHHCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEC
TTGQNAVQQAREFTKFVNVTGLVMTKLDGTSKGGIVLSISRELNLPVKYIGVGEKIDDLQ
CCCHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEEEECCCCCCEEEEECCCCCHHHH
LFDRKSFVEALLEKEK
HHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7584053; 9384377; 8654983 [H]