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The map label for this gene is accA [H]

Identifier: 21673002

GI number: 21673002

Start: 167948

End: 168952

Strand: Direct

Name: accA [H]

Synonym: CT0161

Alternate gene names: 21673002

Gene position: 167948-168952 (Clockwise)

Preceding gene: 21673001

Following gene: 21673006

Centisome position: 7.79

GC content: 56.52

Gene sequence:

>1005_bases
ATGGCGGCGAAAGTAGTTCTCGATTTTGAAAAACCCCTTTATGAGCTTGAAGAGAAGCTCAATGAAATGAGGGTTTACTT
GAAAAGCGGCGAGGTCGATTCAATGTCGGAAGGCCGCGCAGGCCTGAAGCGCGAGATCGAATCGCTTGAAGCAAAGGTCG
AATCGCTTCGCAAAACGATCTACAAGAATCTGACCCGCTGGCAGAAGGTGCAGCTGGCCCGGCACCCGGAACGCCCCTAT
ACGCTCGATTACATCTACATGATGATGAAGGATTTCGTCGAGCTGTCAGGTGATCGTAACTTTGGCGATGACAAAGCGAT
CATCGGCGGCTTTGCCCGGCTTGAGGACGAATCAGCCGGTTTCTCGCAAAGCGTGATGGTCATCGGCCACCAGAAGGGGC
GTGACACCAAATCGAACCTTTACCGCAACTTCGGCATGGCGCAGCCCGAGGGCTACCGCAAGGCGCTGCGTCTCATGAAG
CTCGCGGAGAAGTTCCGCAAACCCGTCATCACGCTGATCGATACTCCGGGTGCGTTTCCTGGCATCGAGGCCGAGGAGCG
CGGACAGGCCGAGGCCATTGCTCGCAACCTTTATGAAATGGCTGCTCTGAAAGTGCCGGTCATCTGCGTTATCATCGGCG
AAGGGGCCAGCGGGGGAGCTATCGGCATCGGCGTCGGCGACCGTATTCTCATGGCTGAAAACGCCTGGTACTCGGTCATC
TCGCCGGAAAGCTGTTCATCAATTCTCTGGCGGAGCTGGAACTTCAAGGAGCAGGCCGCAGAAGCGCTCAAGCTCACGGC
GGACGATCTGCTCGCTCAGGGCATCATCGACCGGATCGTGACCGAACCTCTCGGTGGCGCGCATCACAACCCCGAACAGA
TGGCCTCAACGCTCAAGTCGATTTTGATCGAGGAGTTGCAGGGCTTGCTCACAAAAGATGCTCGTACACTGGTGGACGAA
CGAATCGCGAAGTTCTCAGGAATGGGCGTGTGGGAAGAGAGCTGA

Upstream 100 bases:

>100_bases
GCTGAGCCATTACCGGAGCTTACAAGCTCATCGAACGAGTTTTCAAGGTCCATCATTGGCATGAGCAGTGATGGACTTTT
TTTTAAGGAGCAAGCATACT

Downstream 100 bases:

>100_bases
CCGTTTTTCAAAGCGAAACCCGAAAAGCAGTCTCGACTTGTCGGGACTGTTTTTTTTACGTCATCGTTTTCTTGTTCTGT
TCACGCCATTTACCAAGTCC

Product: acetyl-CoA carboxylase carboxyltransferase subunit alpha

Products: NA

Alternate protein names: ACCase subunit alpha; Acetyl-CoA carboxylase carboxyltransferase subunit alpha [H]

Number of amino acids: Translated: 334; Mature: 333

Protein sequence:

>334_residues
MAAKVVLDFEKPLYELEEKLNEMRVYLKSGEVDSMSEGRAGLKREIESLEAKVESLRKTIYKNLTRWQKVQLARHPERPY
TLDYIYMMMKDFVELSGDRNFGDDKAIIGGFARLEDESAGFSQSVMVIGHQKGRDTKSNLYRNFGMAQPEGYRKALRLMK
LAEKFRKPVITLIDTPGAFPGIEAEERGQAEAIARNLYEMAALKVPVICVIIGEGASGGAIGIGVGDRILMAENAWYSVI
SPESCSSILWRSWNFKEQAAEALKLTADDLLAQGIIDRIVTEPLGGAHHNPEQMASTLKSILIEELQGLLTKDARTLVDE
RIAKFSGMGVWEES

Sequences:

>Translated_334_residues
MAAKVVLDFEKPLYELEEKLNEMRVYLKSGEVDSMSEGRAGLKREIESLEAKVESLRKTIYKNLTRWQKVQLARHPERPY
TLDYIYMMMKDFVELSGDRNFGDDKAIIGGFARLEDESAGFSQSVMVIGHQKGRDTKSNLYRNFGMAQPEGYRKALRLMK
LAEKFRKPVITLIDTPGAFPGIEAEERGQAEAIARNLYEMAALKVPVICVIIGEGASGGAIGIGVGDRILMAENAWYSVI
SPESCSSILWRSWNFKEQAAEALKLTADDLLAQGIIDRIVTEPLGGAHHNPEQMASTLKSILIEELQGLLTKDARTLVDE
RIAKFSGMGVWEES
>Mature_333_residues
AAKVVLDFEKPLYELEEKLNEMRVYLKSGEVDSMSEGRAGLKREIESLEAKVESLRKTIYKNLTRWQKVQLARHPERPYT
LDYIYMMMKDFVELSGDRNFGDDKAIIGGFARLEDESAGFSQSVMVIGHQKGRDTKSNLYRNFGMAQPEGYRKALRLMKL
AEKFRKPVITLIDTPGAFPGIEAEERGQAEAIARNLYEMAALKVPVICVIIGEGASGGAIGIGVGDRILMAENAWYSVIS
PESCSSILWRSWNFKEQAAEALKLTADDLLAQGIIDRIVTEPLGGAHHNPEQMASTLKSILIEELQGLLTKDARTLVDER
IAKFSGMGVWEES

Specific function: Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-Co

COG id: COG0825

COG function: function code I; Acetyl-CoA carboxylase alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AccA family [H]

Homologues:

Organism=Escherichia coli, GI1786382, Length=323, Percent_Identity=50.7739938080495, Blast_Score=332, Evalue=2e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001095
- InterPro:   IPR011763 [H]

Pfam domain/function: PF03255 ACCA [H]

EC number: =6.4.1.2 [H]

Molecular weight: Translated: 37325; Mature: 37194

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAKVVLDFEKPLYELEEKLNEMRVYLKSGEVDSMSEGRAGLKREIESLEAKVESLRKTI
CCCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YKNLTRWQKVQLARHPERPYTLDYIYMMMKDFVELSGDRNFGDDKAIIGGFARLEDESAG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCC
FSQSVMVIGHQKGRDTKSNLYRNFGMAQPEGYRKALRLMKLAEKFRKPVITLIDTPGAFP
CCCEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
GIEAEERGQAEAIARNLYEMAALKVPVICVIIGEGASGGAIGIGVGDRILMAENAWYSVI
CCCCHHCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCEEEEECCCEEECC
SPESCSSILWRSWNFKEQAAEALKLTADDLLAQGIIDRIVTEPLGGAHHNPEQMASTLKS
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
ILIEELQGLLTKDARTLVDERIAKFSGMGVWEES
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
AAKVVLDFEKPLYELEEKLNEMRVYLKSGEVDSMSEGRAGLKREIESLEAKVESLRKTI
CCEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YKNLTRWQKVQLARHPERPYTLDYIYMMMKDFVELSGDRNFGDDKAIIGGFARLEDESAG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCC
FSQSVMVIGHQKGRDTKSNLYRNFGMAQPEGYRKALRLMKLAEKFRKPVITLIDTPGAFP
CCCEEEEEECCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCC
GIEAEERGQAEAIARNLYEMAALKVPVICVIIGEGASGGAIGIGVGDRILMAENAWYSVI
CCCCHHCCHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCEEEEECCCEEECC
SPESCSSILWRSWNFKEQAAEALKLTADDLLAQGIIDRIVTEPLGGAHHNPEQMASTLKS
CCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
ILIEELQGLLTKDARTLVDERIAKFSGMGVWEES
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA