| Definition | Chlorobium tepidum TLS, complete genome. |
|---|---|
| Accession | NC_002932 |
| Length | 2,154,946 |
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The map label for this gene is hetN [H]
Identifier: 21672989
GI number: 21672989
Start: 151044
End: 151841
Strand: Direct
Name: hetN [H]
Synonym: CT0148
Alternate gene names: 21672989
Gene position: 151044-151841 (Clockwise)
Preceding gene: 21672988
Following gene: 21672990
Centisome position: 7.01
GC content: 60.03
Gene sequence:
>798_bases ATGAGCTTTTATACGCTGATTACGGGCGCGTCCACCGGTATCGGCCGGCGACTTGCTGAAGAGTTTGCCTCGATGGGCGA CAACCTCGTGCTGGTTGCCCGCTCGCAGGATAAGCTTGAAACGCTGGCTGCGGAGTTGCGTCGCTCATGCGGTATCGAGG TGCAGGTCTGTTGCCAGGATCTTGCGGAGGTTGGCGCTGCGTTGAAGGTTTTCGGATTCTGCGAGGAGAGAGGGCTGCCC ATCGATAAACTGGTCAACTGCGCCGGATTCTCCATAGCGGGCAACTTTGAGCGGATGGACGAAGAGACGTTCGTGCAGAT GGTCTTGGTCAATATGGTCGCCGTGGCTGCGCTGACCCGCCGGTTTCTTCCGGCGATGCGCGCCCGCCGCCGGGGTGTGG TGATCAATATCGCTTCGCTCGCCGGATTCCAGGGTGTGCCGGGTATGGCCGGCTACTCCGCCAGCAAGGCGTTTGTGGTC AATCTGACCGAAGCGCTCTCTGTCGAGCTTCAGGGCACTGGCGTCCGAATCTTCGCCGTCTGTCCCAGCTTTCTCGACAA CGATCTCTTTTACAGCCGTGCCGGTCATGACCGGAGCCGCATCGTCACGCCGGTTTCCAGTCCGGAGGTGGTCGTGAAGG CCGTCCACCGCGGACTCGACGGAAAACAGGTGCTGATTCTGCCGACCGTTCTGGATCGTCTCATGGTTTTTGTCCAGCGT TTCACACCACGGAAAATCGTGGTGTTGCTGGCCGATATCTTCGCCGGAGCCAGGGAGAGGGGGGGGAGTAATGGGTGA
Upstream 100 bases:
>100_bases ACGTCGGCAAAGAGTGTGTCGAGGAGAACATCCCGGAGGCAGAGGCGCTTGAGCGGCTGATTGAGCTGATCCGGCAGAAC GGCAAGTGGGTTGATCCTGT
Downstream 100 bases:
>100_bases TGACTGTACGTGCCGTGTGGTTTTCCTGTCGCGATTTCCGTCATTTATGCTCATTACGCCCATCAAGTTCACTTTGGCCG CGGTTTTTCATGAAATTTTT
Product: short chain dehydrogenase/reductase family oxidoreductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 265; Mature: 264
Protein sequence:
>265_residues MSFYTLITGASTGIGRRLAEEFASMGDNLVLVARSQDKLETLAAELRRSCGIEVQVCCQDLAEVGAALKVFGFCEERGLP IDKLVNCAGFSIAGNFERMDEETFVQMVLVNMVAVAALTRRFLPAMRARRRGVVINIASLAGFQGVPGMAGYSASKAFVV NLTEALSVELQGTGVRIFAVCPSFLDNDLFYSRAGHDRSRIVTPVSSPEVVVKAVHRGLDGKQVLILPTVLDRLMVFVQR FTPRKIVVLLADIFAGARERGGSNG
Sequences:
>Translated_265_residues MSFYTLITGASTGIGRRLAEEFASMGDNLVLVARSQDKLETLAAELRRSCGIEVQVCCQDLAEVGAALKVFGFCEERGLP IDKLVNCAGFSIAGNFERMDEETFVQMVLVNMVAVAALTRRFLPAMRARRRGVVINIASLAGFQGVPGMAGYSASKAFVV NLTEALSVELQGTGVRIFAVCPSFLDNDLFYSRAGHDRSRIVTPVSSPEVVVKAVHRGLDGKQVLILPTVLDRLMVFVQR FTPRKIVVLLADIFAGARERGGSNG >Mature_264_residues SFYTLITGASTGIGRRLAEEFASMGDNLVLVARSQDKLETLAAELRRSCGIEVQVCCQDLAEVGAALKVFGFCEERGLPI DKLVNCAGFSIAGNFERMDEETFVQMVLVNMVAVAALTRRFLPAMRARRRGVVINIASLAGFQGVPGMAGYSASKAFVVN LTEALSVELQGTGVRIFAVCPSFLDNDLFYSRAGHDRSRIVTPVSSPEVVVKAVHRGLDGKQVLILPTVLDRLMVFVQRF TPRKIVVLLADIFAGARERGGSNG
Specific function: May be involved in repressing heterocyst differentiation and may be essential for preventing all vegetative cells from differentiating [H]
COG id: COG0300
COG function: function code R; Short-chain dehydrogenases of various substrate specificities
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI7705855, Length=219, Percent_Identity=31.0502283105023, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI4503817, Length=224, Percent_Identity=31.6964285714286, Blast_Score=100, Evalue=2e-21, Organism=Homo sapiens, GI40807363, Length=251, Percent_Identity=30.6772908366534, Blast_Score=94, Evalue=2e-19, Organism=Homo sapiens, GI226371731, Length=218, Percent_Identity=27.0642201834862, Blast_Score=92, Evalue=6e-19, Organism=Homo sapiens, GI210032110, Length=251, Percent_Identity=27.4900398406374, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI20149619, Length=281, Percent_Identity=27.7580071174377, Blast_Score=89, Evalue=4e-18, Organism=Homo sapiens, GI142976729, Length=251, Percent_Identity=29.4820717131474, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI4557649, Length=187, Percent_Identity=31.5508021390374, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI157739938, Length=270, Percent_Identity=24.8148148148148, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI210032112, Length=248, Percent_Identity=24.5967741935484, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI40254992, Length=181, Percent_Identity=28.1767955801105, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI32483357, Length=187, Percent_Identity=28.8770053475936, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI4758504, Length=200, Percent_Identity=28, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI7706318, Length=192, Percent_Identity=29.6875, Blast_Score=70, Evalue=3e-12, Organism=Homo sapiens, GI310128830, Length=260, Percent_Identity=27.6923076923077, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI310115468, Length=260, Percent_Identity=27.6923076923077, Blast_Score=68, Evalue=7e-12, Organism=Homo sapiens, GI31542939, Length=190, Percent_Identity=29.4736842105263, Blast_Score=67, Evalue=1e-11, Organism=Homo sapiens, GI109715829, Length=224, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI5031737, Length=199, Percent_Identity=29.6482412060301, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI33667109, Length=191, Percent_Identity=29.8429319371728, Blast_Score=66, Evalue=3e-11, Organism=Homo sapiens, GI119392083, Length=180, Percent_Identity=30, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI7705925, Length=181, Percent_Identity=29.2817679558011, Blast_Score=65, Evalue=5e-11, Organism=Escherichia coli, GI87082100, Length=186, Percent_Identity=37.0967741935484, Blast_Score=93, Evalue=1e-20, Organism=Escherichia coli, GI1787335, Length=202, Percent_Identity=29.2079207920792, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1787820, Length=181, Percent_Identity=29.8342541436464, Blast_Score=79, Evalue=4e-16, Organism=Escherichia coli, GI87082160, Length=198, Percent_Identity=28.2828282828283, Blast_Score=72, Evalue=4e-14, Organism=Escherichia coli, GI1790717, Length=187, Percent_Identity=28.8770053475936, Blast_Score=66, Evalue=2e-12, Organism=Escherichia coli, GI1786812, Length=188, Percent_Identity=29.2553191489362, Blast_Score=64, Evalue=8e-12, Organism=Escherichia coli, GI1786701, Length=194, Percent_Identity=27.8350515463918, Blast_Score=62, Evalue=4e-11, Organism=Caenorhabditis elegans, GI193203117, Length=253, Percent_Identity=30.8300395256917, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI193203115, Length=253, Percent_Identity=30.8300395256917, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17508895, Length=258, Percent_Identity=28.6821705426357, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17564282, Length=253, Percent_Identity=26.8774703557312, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI212646214, Length=209, Percent_Identity=27.7511961722488, Blast_Score=84, Evalue=5e-17, Organism=Caenorhabditis elegans, GI17538182, Length=215, Percent_Identity=29.7674418604651, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI25152911, Length=189, Percent_Identity=29.6296296296296, Blast_Score=80, Evalue=2e-15, Organism=Caenorhabditis elegans, GI17557668, Length=210, Percent_Identity=27.6190476190476, Blast_Score=76, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71994600, Length=197, Percent_Identity=29.9492385786802, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17559552, Length=210, Percent_Identity=27.1428571428571, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI71994604, Length=196, Percent_Identity=31.1224489795918, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17562904, Length=195, Percent_Identity=29.7435897435897, Blast_Score=71, Evalue=4e-13, Organism=Caenorhabditis elegans, GI17560176, Length=191, Percent_Identity=27.7486910994764, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17560150, Length=183, Percent_Identity=27.3224043715847, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17560676, Length=185, Percent_Identity=22.7027027027027, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17561402, Length=203, Percent_Identity=23.6453201970443, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17562906, Length=184, Percent_Identity=29.3478260869565, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17536025, Length=197, Percent_Identity=28.9340101522843, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17562908, Length=184, Percent_Identity=28.2608695652174, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI25147288, Length=189, Percent_Identity=27.5132275132275, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17562910, Length=192, Percent_Identity=27.6041666666667, Blast_Score=65, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17562990, Length=186, Percent_Identity=27.4193548387097, Blast_Score=64, Evalue=9e-11, Organism=Saccharomyces cerevisiae, GI6319635, Length=229, Percent_Identity=28.82096069869, Blast_Score=87, Evalue=2e-18, Organism=Saccharomyces cerevisiae, GI6323882, Length=245, Percent_Identity=30.6122448979592, Blast_Score=82, Evalue=1e-16, Organism=Saccharomyces cerevisiae, GI6322861, Length=190, Percent_Identity=29.4736842105263, Blast_Score=71, Evalue=2e-13, Organism=Drosophila melanogaster, GI28574402, Length=186, Percent_Identity=31.1827956989247, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI24584744, Length=186, Percent_Identity=31.1827956989247, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI24584748, Length=189, Percent_Identity=29.6296296296296, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI161076933, Length=189, Percent_Identity=29.6296296296296, Blast_Score=106, Evalue=2e-23, Organism=Drosophila melanogaster, GI24640442, Length=246, Percent_Identity=31.3008130081301, Blast_Score=103, Evalue=8e-23, Organism=Drosophila melanogaster, GI24584752, Length=194, Percent_Identity=32.9896907216495, Blast_Score=102, Evalue=3e-22, Organism=Drosophila melanogaster, GI28571526, Length=196, Percent_Identity=32.1428571428571, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI24644339, Length=192, Percent_Identity=30.2083333333333, Blast_Score=85, Evalue=4e-17, Organism=Drosophila melanogaster, GI21356301, Length=229, Percent_Identity=28.82096069869, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24643142, Length=179, Percent_Identity=32.9608938547486, Blast_Score=81, Evalue=6e-16, Organism=Drosophila melanogaster, GI116007236, Length=194, Percent_Identity=30.4123711340206, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI23397609, Length=185, Percent_Identity=31.8918918918919, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI21357041, Length=197, Percent_Identity=28.9340101522843, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI17737361, Length=217, Percent_Identity=29.4930875576037, Blast_Score=77, Evalue=9e-15, Organism=Drosophila melanogaster, GI21358495, Length=194, Percent_Identity=28.3505154639175, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI116007238, Length=204, Percent_Identity=29.4117647058824, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI24639444, Length=192, Percent_Identity=29.1666666666667, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24581726, Length=245, Percent_Identity=22.8571428571429, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 28663; Mature: 28532
Theoretical pI: Translated: 8.61; Mature: 8.61
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.3 %Cys (Translated Protein) 3.0 %Met (Translated Protein) 5.3 %Cys+Met (Translated Protein) 2.3 %Cys (Mature Protein) 2.7 %Met (Mature Protein) 4.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSFYTLITGASTGIGRRLAEEFASMGDNLVLVARSQDKLETLAAELRRSCGIEVQVCCQD CCEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHH LAEVGAALKVFGFCEERGLPIDKLVNCAGFSIAGNFERMDEETFVQMVLVNMVAVAALTR HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHH RFLPAMRARRRGVVINIASLAGFQGVPGMAGYSASKAFVVNLTEALSVELQGTGVRIFAV HHHHHHHHHCCCEEEEEHHHCCCCCCCCCCCCCCCCEEEEEEHHHHEEEECCCCEEEEEE CPSFLDNDLFYSRAGHDRSRIVTPVSSPEVVVKAVHRGLDGKQVLILPTVLDRLMVFVQR CHHHHCCCHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHH FTPRKIVVLLADIFAGARERGGSNG CCCHHHHHHHHHHHHHHHHCCCCCC >Mature Secondary Structure SFYTLITGASTGIGRRLAEEFASMGDNLVLVARSQDKLETLAAELRRSCGIEVQVCCQD CEEEEEECCCCHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHCCCCHHHHHHH LAEVGAALKVFGFCEERGLPIDKLVNCAGFSIAGNFERMDEETFVQMVLVNMVAVAALTR HHHHHHHHHHHHHHHHCCCCHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHH RFLPAMRARRRGVVINIASLAGFQGVPGMAGYSASKAFVVNLTEALSVELQGTGVRIFAV HHHHHHHHHCCCEEEEEHHHCCCCCCCCCCCCCCCCEEEEEEHHHHEEEECCCCEEEEEE CPSFLDNDLFYSRAGHDRSRIVTPVSSPEVVVKAVHRGLDGKQVLILPTVLDRLMVFVQR CHHHHCCCHHHHCCCCCCCEEECCCCCHHHHHHHHHCCCCCCEEEEHHHHHHHHHHHHHH FTPRKIVVLLADIFAGARERGGSNG CCCHHHHHHHHHHHHHHHHCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 8157596; 11759840 [H]