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The map label for this gene is gcp

Identifier: 21672905

GI number: 21672905

Start: 64534

End: 65595

Strand: Direct

Name: gcp

Synonym: CT0064

Alternate gene names: 21672905

Gene position: 64534-65595 (Clockwise)

Preceding gene: 21672901

Following gene: 21672906

Centisome position: 2.99

GC content: 60.64

Gene sequence:

>1062_bases
ATGAATATTTTAGGGATAGAAACCAGTTGCGACGAAACCTCGGCGGCTGTCCTCAGCGATGGATCGGTCCGGTCGAACAT
TGTCAGTTCTCAGCGATGCCATACCGATTTCGGCGGTGTGGTGCCGGAGCTGGCTTCACGGGAGCATGAGCGACTGATCG
TCTCGATCGTGGATGCCGCCATAACCGAAGCAAATATAGCAAAAAATGACCTCGATGTCATAGCCGCTACCGCCGGGCCG
GGGCTGATCGGCGCGGTGATGGTGGGGCTTTGCTTTGCCGAGGGCCTGGCCTGGGCGCTTGGCAAGCCCTTCGTGCCGGT
CAACCATGTCGAGGCGCACATCTTTTCACCCTTCATCAGCGACGAACCTGGCCACCGCGAGCCGAAGGGCGACTTCGTTT
CGCTGACCGTCTCCGGAGGCCACACATTGCTGTCGGTCGTGCGGCAGGATCTGGGCTACGAGGTAATCGGACGCACCATC
GACGACGCGGCGGGCGAGGCGTTCGACAAGACCGGCAAGATGCTTGGCCTCGGTTATCCGGCGGGGCCGGTGATCGACCG
GCTTGCCCGCGAGGGCGATTCGGATTTCCACCGTTTTCCCCGAGCCCTGACCGCAAGTTCGCAGACAAGCAAGAGTTACC
GGGGCAACTTCGACTTCAGCTTCTCTGGCCTCAAAACCTCCGTGCGCACCTGGCTCGAAGCTCACGACTCGGAGTATGTC
CAAAAGCATCAGGCTGACCTTGCAGCCTCAATCCAGTCAGCGATTGTTGAGGTGCTGGTCGAAAAGAGCGTCGCCGCCGC
GCTCTTGCATAAAGTCAATGCCATTTCGGTGGCGGGCGGCGTGAGCGCCAACTCCGGCCTCCGCTCGGCGATGCAGGCGG
CCTGCGACCGGCACGGCATCGAACTCTTCATTCCCGCGCTCGCCTACTCGACCGACAATGCAGCAATGATCGCCACCATG
GCGCAGTTGATGATTGCGCGAGGCAAGTACCGGATCGAGGATAATTCCTATGGCGTAGCGCCTTTTGCCCGCTTCGAGGC
AGCCAGAAAAGGGGCGCGTTGA

Upstream 100 bases:

>100_bases
GAGAATCATGAACGCCTTCAAAAAGCTTATCCTGACGCGCGGTTTGCTATTGTTCTCCTCTTTCTTAGCTTTGGCCATTA
CGCATTTCCTCTCTTGAGCG

Downstream 100 bases:

>100_bases
AATAGTTTGGGAAATAAATTATCTTCGGATTCGAAAAAAAAGCGCCCTATCCGGCCCGAATGTTGCCGGAGAGCCCAGCT
CCGAATACCAACCGCAAGCT

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MNILGIETSCDETSAAVLSDGSVRSNIVSSQRCHTDFGGVVPELASREHERLIVSIVDAAITEANIAKNDLDVIAATAGP
GLIGAVMVGLCFAEGLAWALGKPFVPVNHVEAHIFSPFISDEPGHREPKGDFVSLTVSGGHTLLSVVRQDLGYEVIGRTI
DDAAGEAFDKTGKMLGLGYPAGPVIDRLAREGDSDFHRFPRALTASSQTSKSYRGNFDFSFSGLKTSVRTWLEAHDSEYV
QKHQADLAASIQSAIVEVLVEKSVAAALLHKVNAISVAGGVSANSGLRSAMQAACDRHGIELFIPALAYSTDNAAMIATM
AQLMIARGKYRIEDNSYGVAPFARFEAARKGAR

Sequences:

>Translated_353_residues
MNILGIETSCDETSAAVLSDGSVRSNIVSSQRCHTDFGGVVPELASREHERLIVSIVDAAITEANIAKNDLDVIAATAGP
GLIGAVMVGLCFAEGLAWALGKPFVPVNHVEAHIFSPFISDEPGHREPKGDFVSLTVSGGHTLLSVVRQDLGYEVIGRTI
DDAAGEAFDKTGKMLGLGYPAGPVIDRLAREGDSDFHRFPRALTASSQTSKSYRGNFDFSFSGLKTSVRTWLEAHDSEYV
QKHQADLAASIQSAIVEVLVEKSVAAALLHKVNAISVAGGVSANSGLRSAMQAACDRHGIELFIPALAYSTDNAAMIATM
AQLMIARGKYRIEDNSYGVAPFARFEAARKGAR
>Mature_353_residues
MNILGIETSCDETSAAVLSDGSVRSNIVSSQRCHTDFGGVVPELASREHERLIVSIVDAAITEANIAKNDLDVIAATAGP
GLIGAVMVGLCFAEGLAWALGKPFVPVNHVEAHIFSPFISDEPGHREPKGDFVSLTVSGGHTLLSVVRQDLGYEVIGRTI
DDAAGEAFDKTGKMLGLGYPAGPVIDRLAREGDSDFHRFPRALTASSQTSKSYRGNFDFSFSGLKTSVRTWLEAHDSEYV
QKHQADLAASIQSAIVEVLVEKSVAAALLHKVNAISVAGGVSANSGLRSAMQAACDRHGIELFIPALAYSTDNAAMIATM
AQLMIARGKYRIEDNSYGVAPFARFEAARKGAR

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=339, Percent_Identity=32.7433628318584, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI8923380, Length=349, Percent_Identity=29.512893982808, Blast_Score=100, Evalue=4e-21,
Organism=Escherichia coli, GI1789445, Length=320, Percent_Identity=42.1875, Blast_Score=244, Evalue=9e-66,
Organism=Caenorhabditis elegans, GI17557464, Length=340, Percent_Identity=27.6470588235294, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71995670, Length=338, Percent_Identity=29.585798816568, Blast_Score=112, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320099, Length=339, Percent_Identity=29.7935103244838, Blast_Score=133, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6322891, Length=295, Percent_Identity=26.7796610169492, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20129063, Length=337, Percent_Identity=31.1572700296736, Blast_Score=138, Evalue=5e-33,
Organism=Drosophila melanogaster, GI21357207, Length=354, Percent_Identity=28.5310734463277, Blast_Score=122, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_CHLTE (Q8KGA4)

Other databases:

- EMBL:   AE006470
- RefSeq:   NP_660970.1
- ProteinModelPortal:   Q8KGA4
- SMR:   Q8KGA4
- MEROPS:   M22.001
- GeneID:   1006484
- GenomeReviews:   AE006470_GR
- KEGG:   cte:CT0064
- NMPDR:   fig|194439.1.peg.64
- TIGR:   CT0064
- HOGENOM:   HBG304663
- OMA:   PAVGVHH
- ProtClustDB:   PRK09604
- BioCyc:   CTEP194439:CT_0064-MONOMER
- BRENDA:   3.4.24.57
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017861
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 37476; Mature: 37476

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNILGIETSCDETSAAVLSDGSVRSNIVSSQRCHTDFGGVVPELASREHERLIVSIVDAA
CCEECCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCHHCCHHHHHHCCHHHHHHHHHHHHH
ITEANIAKNDLDVIAATAGPGLIGAVMVGLCFAEGLAWALGKPFVPVNHVEAHIFSPFIS
HHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHC
DEPGHREPKGDFVSLTVSGGHTLLSVVRQDLGYEVIGRTIDDAAGEAFDKTGKMLGLGYP
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCHHHHHCHHHHHHHHHHHHCCCEEECCCC
AGPVIDRLAREGDSDFHRFPRALTASSQTSKSYRGNFDFSFSGLKTSVRTWLEAHDSEYV
CHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHCCCCCEEHHHHHHHHHHHHHHHHHHHH
QKHQADLAASIQSAIVEVLVEKSVAAALLHKVNAISVAGGVSANSGLRSAMQAACDRHGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCC
ELFIPALAYSTDNAAMIATMAQLMIARGKYRIEDNSYGVAPFARFEAARKGAR
EEEEEHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MNILGIETSCDETSAAVLSDGSVRSNIVSSQRCHTDFGGVVPELASREHERLIVSIVDAA
CCEECCCCCCCCCHHHHHCCCCHHHHHHHHHHCCCHHCCHHHHHHCCHHHHHHHHHHHHH
ITEANIAKNDLDVIAATAGPGLIGAVMVGLCFAEGLAWALGKPFVPVNHVEAHIFSPFIS
HHHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHC
DEPGHREPKGDFVSLTVSGGHTLLSVVRQDLGYEVIGRTIDDAAGEAFDKTGKMLGLGYP
CCCCCCCCCCCEEEEEECCCHHHHHHHHHHHCHHHHHCHHHHHHHHHHHHCCCEEECCCC
AGPVIDRLAREGDSDFHRFPRALTASSQTSKSYRGNFDFSFSGLKTSVRTWLEAHDSEYV
CHHHHHHHHHCCCHHHHHHHHHHHCCCCCCHHHCCCCCEEHHHHHHHHHHHHHHHHHHHH
QKHQADLAASIQSAIVEVLVEKSVAAALLHKVNAISVAGGVSANSGLRSAMQAACDRHGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHHHHCCC
ELFIPALAYSTDNAAMIATMAQLMIARGKYRIEDNSYGVAPFARFEAARKGAR
EEEEEHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12093901