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The map label for this gene is feoB-2 [H]

Identifier: 21672897

GI number: 21672897

Start: 56948

End: 59086

Strand: Reverse

Name: feoB-2 [H]

Synonym: CT0056

Alternate gene names: 21672897

Gene position: 59086-56948 (Counterclockwise)

Preceding gene: 21672898

Following gene: 21672895

Centisome position: 2.74

GC content: 60.64

Gene sequence:

>2139_bases
ATGAGCCAGCAGAAAACCATTACGGTCGCGCTTGCCGGAAATCCGAACGCGGGCAAGTCTTCGCTGTTCAACGCGCTGAC
CGGCGCTCACCAGCGCGTAGGAAATTTCCCCGGCGTAACCATCGAAAAGCACGAAGGTTATCTCGATTACAAAGGCTACC
GCATCACCGTGGTCGATCTGCCCGGCACCTATTCGCTGACGCCGTACTCACCGGAGGAGATCGTCACCCGCCGCTTCATC
ATCGACGAGAAACCAGATGTGGTGGTGAACGTCGTCGAGGGCACCAACCTCGAACGCAACCTCATGCTGACCGTGCAGCT
CATGGAGATGGAAGTCGATCTGCTCGTGGCGCTCAACATGATGGACGAGGTGGAGGAGAAAGGAATTTCCATCGATCTCG
ACCAGCTCGAACAGCTCTTCGGCAGCCACATCGTGCCGATCTCCGCGCGCAATCGCAAGGGGCTCGACGAGCTGCTCGAC
CACATCGTCAGCGTCAGCGAAGGGCGAATCGAGATCAAGAAAAACAAAATCACCTTCAGCGCCGAGGTCGAGAAGGCTAT
CGACAAGATCGCCCTCCTGCTGGCTCACGAGCGCGAACTCGACGCAGCAGCCAACCACCGCTGGCTCGCCATCAAGCTGC
TTGAAAACGACCGCGAGGTCTACACCCAGGTGCAGAAATTTCCGGTGTGGGTCAAAATCGAGCTGGCGTTGCAGGAGGCG
ATCACGGAGTGCGGCATTCTGCACAACACCGATCCCGAAGCGCTCATCACCGAAGACCGGCACGCTTTCGTGCGCGGCGC
GATGCAGGAGTGCGTTCACCTGCCGAAGGCCACACGAGCCTCGGTGAGCGACTACATCGACATGGTGGTGCTGAACCGGG
TACTCGGCCTGCCGGTCTTTTTTCTCGTCGTCTGGGCGATCTTCCAGCTCACCTTCACGCTCGGCAAGCCGCTGGTGGAG
GCGCTCGCCTACGCCTTCGACCTGCTTTCGGACACCGTCGCGCCGCACTTGCCCGCCGGAATGGTGCGTTCGATCTTTGT
TGACGGCGTGATCTCAGGCGTCGGCAGCGTGGTGGAGTTCCTGCCAAACATCGTGCTGCTTTTCATGGGGCTGTCGTTCC
TCGAAGCCTCTGGCTACATGGCGCGTGCGGCCTTCGTGATCGACAAGGTGATGCACCGCTTCGGCCTGCACGGCAAGTCG
TTCATTCCGATGATCACCGGCTTCGGCTGCTCGATTCCGGCCATCATGGCGACGCGAACGCTCAAGAGCCGGTCGGATCG
TCTCGCCACCATCATGACGATTCCCTTCATGAGCTGCAGCGCAAAACTGCCGGTCTACGTGCTGCTCGCAGGAGCATTCT
TCCCGCCAGCGATGGCCGCCAACGTGATGTTCGGCATCTACCTGCTCGGCATCATGATCGGCCTCTGGACGGCGTGGCTG
CTGAAATCGACCGTGCTGAAGAGCGACTCGGAGCCCTTCGTGATGGAGCTGCCGCCCTACCGCTGGCCGACGCTCACTTC
GGTGGTATTTCAGGCGCGGATGAAGGCCGTGATGTACCTCAAAAAAGCCGGAACGCTGATTCTCGGCGCGGTAATCGTGA
TTTGGGCGGCGAGCAACTTCCCGCGCAGCTCGGCGCTCGACGCGGAGCTTGCACAAGAGAAGGCGAAGATCGAGGCAACG
GCGGTCGCACCGGAGCTGAAAGCGGAGCAGTTGCAGAAGCTCAAAGCGCGAATCGACGCAGGCCAGCTCGAATACTCGCT
CGCCGGACGGAGCGGGAAACTGCTCGAACCGCTCATCCGCCCGCTCGGCTTCGACTGGCGCATCGGCATCTCGCTGGTCA
CGGGCCTCGCGGCAAAAGAGGTGGTGGTTTCGACGCTCGGCACGATTTTCTCGATCGGTCACGCCGCCGGACAGACAAGC
CTGTCGCAAATTCTTCGGAGCGATCCCAGCTTCAGCAAAGCCACGGCGCTGAGCCTGATGGTGTTCGTGCTGCTCTACAT
CCCCTGCGTGGCATCGGTAGGCGTAATGAAAAAAGAGGTCGGCGCATGGAAGCCGGTGCTCCTCTACTCCGTCTATGTGC
TCGCCGTGGCCTGGATCGCCTCGTTCATCACCTACCACCTCGCGCTCTTGTGGCTGTGA

Upstream 100 bases:

>100_bases
ACGAGGCCGAAGGGATTACCGTACACATACTGGCCGGGGACGAAGGGCATCCGCACGGATGGCCGGGCTTCCGCAGACGC
CACCGTTTCGGAAAACGCGC

Downstream 100 bases:

>100_bases
GGAGAATCCCTTCTTTAACAATCTCCCCAAACGAAAAACGGCTGTCTTTCCTGGCAGCCGTTTTCATATAACTCCTATAG
GACTTATATGACCTACAGGT

Product: ferrous iron transport protein B

Products: Fe (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 712; Mature: 711

Protein sequence:

>712_residues
MSQQKTITVALAGNPNAGKSSLFNALTGAHQRVGNFPGVTIEKHEGYLDYKGYRITVVDLPGTYSLTPYSPEEIVTRRFI
IDEKPDVVVNVVEGTNLERNLMLTVQLMEMEVDLLVALNMMDEVEEKGISIDLDQLEQLFGSHIVPISARNRKGLDELLD
HIVSVSEGRIEIKKNKITFSAEVEKAIDKIALLLAHERELDAAANHRWLAIKLLENDREVYTQVQKFPVWVKIELALQEA
ITECGILHNTDPEALITEDRHAFVRGAMQECVHLPKATRASVSDYIDMVVLNRVLGLPVFFLVVWAIFQLTFTLGKPLVE
ALAYAFDLLSDTVAPHLPAGMVRSIFVDGVISGVGSVVEFLPNIVLLFMGLSFLEASGYMARAAFVIDKVMHRFGLHGKS
FIPMITGFGCSIPAIMATRTLKSRSDRLATIMTIPFMSCSAKLPVYVLLAGAFFPPAMAANVMFGIYLLGIMIGLWTAWL
LKSTVLKSDSEPFVMELPPYRWPTLTSVVFQARMKAVMYLKKAGTLILGAVIVIWAASNFPRSSALDAELAQEKAKIEAT
AVAPELKAEQLQKLKARIDAGQLEYSLAGRSGKLLEPLIRPLGFDWRIGISLVTGLAAKEVVVSTLGTIFSIGHAAGQTS
LSQILRSDPSFSKATALSLMVFVLLYIPCVASVGVMKKEVGAWKPVLLYSVYVLAVAWIASFITYHLALLWL

Sequences:

>Translated_712_residues
MSQQKTITVALAGNPNAGKSSLFNALTGAHQRVGNFPGVTIEKHEGYLDYKGYRITVVDLPGTYSLTPYSPEEIVTRRFI
IDEKPDVVVNVVEGTNLERNLMLTVQLMEMEVDLLVALNMMDEVEEKGISIDLDQLEQLFGSHIVPISARNRKGLDELLD
HIVSVSEGRIEIKKNKITFSAEVEKAIDKIALLLAHERELDAAANHRWLAIKLLENDREVYTQVQKFPVWVKIELALQEA
ITECGILHNTDPEALITEDRHAFVRGAMQECVHLPKATRASVSDYIDMVVLNRVLGLPVFFLVVWAIFQLTFTLGKPLVE
ALAYAFDLLSDTVAPHLPAGMVRSIFVDGVISGVGSVVEFLPNIVLLFMGLSFLEASGYMARAAFVIDKVMHRFGLHGKS
FIPMITGFGCSIPAIMATRTLKSRSDRLATIMTIPFMSCSAKLPVYVLLAGAFFPPAMAANVMFGIYLLGIMIGLWTAWL
LKSTVLKSDSEPFVMELPPYRWPTLTSVVFQARMKAVMYLKKAGTLILGAVIVIWAASNFPRSSALDAELAQEKAKIEAT
AVAPELKAEQLQKLKARIDAGQLEYSLAGRSGKLLEPLIRPLGFDWRIGISLVTGLAAKEVVVSTLGTIFSIGHAAGQTS
LSQILRSDPSFSKATALSLMVFVLLYIPCVASVGVMKKEVGAWKPVLLYSVYVLAVAWIASFITYHLALLWL
>Mature_711_residues
SQQKTITVALAGNPNAGKSSLFNALTGAHQRVGNFPGVTIEKHEGYLDYKGYRITVVDLPGTYSLTPYSPEEIVTRRFII
DEKPDVVVNVVEGTNLERNLMLTVQLMEMEVDLLVALNMMDEVEEKGISIDLDQLEQLFGSHIVPISARNRKGLDELLDH
IVSVSEGRIEIKKNKITFSAEVEKAIDKIALLLAHERELDAAANHRWLAIKLLENDREVYTQVQKFPVWVKIELALQEAI
TECGILHNTDPEALITEDRHAFVRGAMQECVHLPKATRASVSDYIDMVVLNRVLGLPVFFLVVWAIFQLTFTLGKPLVEA
LAYAFDLLSDTVAPHLPAGMVRSIFVDGVISGVGSVVEFLPNIVLLFMGLSFLEASGYMARAAFVIDKVMHRFGLHGKSF
IPMITGFGCSIPAIMATRTLKSRSDRLATIMTIPFMSCSAKLPVYVLLAGAFFPPAMAANVMFGIYLLGIMIGLWTAWLL
KSTVLKSDSEPFVMELPPYRWPTLTSVVFQARMKAVMYLKKAGTLILGAVIVIWAASNFPRSSALDAELAQEKAKIEATA
VAPELKAEQLQKLKARIDAGQLEYSLAGRSGKLLEPLIRPLGFDWRIGISLVTGLAAKEVVVSTLGTIFSIGHAAGQTSL
SQILRSDPSFSKATALSLMVFVLLYIPCVASVGVMKKEVGAWKPVLLYSVYVLAVAWIASFITYHLALLWL

Specific function: Fe(2+) uptake system, probably driven by GTP [H]

COG id: COG0370

COG function: function code P; Fe2+ transport system protein B

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1789813, Length=739, Percent_Identity=32.2056833558863, Blast_Score=334, Evalue=1e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007167
- InterPro:   IPR003373
- InterPro:   IPR011640
- InterPro:   IPR011619
- InterPro:   IPR011642
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF04023 FeoA; PF07664 FeoB_C; PF02421 FeoB_N; PF07670 Gate; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 78353; Mature: 78222

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQQKTITVALAGNPNAGKSSLFNALTGAHQRVGNFPGVTIEKHEGYLDYKGYRITVVDL
CCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEECCEEEEEEEC
PGTYSLTPYSPEEIVTRRFIIDEKPDVVVNVVEGTNLERNLMLTVQLMEMEVDLLVALNM
CCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEEHHHHHHHHHHHHHH
MDEVEEKGISIDLDQLEQLFGSHIVPISARNRKGLDELLDHIVSVSEGRIEIKKNKITFS
HHHHHHCCCCCCHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECEEEEH
AEVEKAIDKIALLLAHERELDAAANHRWLAIKLLENDREVYTQVQKFPVWVKIELALQEA
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCEEEEEHHHHHHH
ITECGILHNTDPEALITEDRHAFVRGAMQECVHLPKATRASVSDYIDMVVLNRVLGLPVF
HHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
FLVVWAIFQLTFTLGKPLVEALAYAFDLLSDTVAPHLPAGMVRSIFVDGVISGVGSVVEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LPNIVLLFMGLSFLEASGYMARAAFVIDKVMHRFGLHGKSFIPMITGFGCSIPAIMATRT
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHH
LKSRSDRLATIMTIPFMSCSAKLPVYVLLAGAFFPPAMAANVMFGIYLLGIMIGLWTAWL
HHHCCCCEEEEEEEHHHCCCCCCCCHHEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LKSTVLKSDSEPFVMELPPYRWPTLTSVVFQARMKAVMYLKKAGTLILGAVIVIWAASNF
HHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
PRSSALDAELAQEKAKIEATAVAPELKAEQLQKLKARIDAGQLEYSLAGRSGKLLEPLIR
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHH
PLGFDWRIGISLVTGLAAKEVVVSTLGTIFSIGHAAGQTSLSQILRSDPSFSKATALSLM
HCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHH
VFVLLYIPCVASVGVMKKEVGAWKPVLLYSVYVLAVAWIASFITYHLALLWL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQQKTITVALAGNPNAGKSSLFNALTGAHQRVGNFPGVTIEKHEGYLDYKGYRITVVDL
CCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEECCCCEEEECCEEEEEEEC
PGTYSLTPYSPEEIVTRRFIIDEKPDVVVNVVEGTNLERNLMLTVQLMEMEVDLLVALNM
CCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCEEEEEEEHHHHHHHHHHHHHH
MDEVEEKGISIDLDQLEQLFGSHIVPISARNRKGLDELLDHIVSVSEGRIEIKKNKITFS
HHHHHHCCCCCCHHHHHHHHCCCEEEECCCCCCCHHHHHHHHHCCCCCEEEEEECEEEEH
AEVEKAIDKIALLLAHERELDAAANHRWLAIKLLENDREVYTQVQKFPVWVKIELALQEA
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCHHHHHHHHHCCEEEEEHHHHHHH
ITECGILHNTDPEALITEDRHAFVRGAMQECVHLPKATRASVSDYIDMVVLNRVLGLPVF
HHHCCCCCCCCCCCEEECCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
FLVVWAIFQLTFTLGKPLVEALAYAFDLLSDTVAPHLPAGMVRSIFVDGVISGVGSVVEF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
LPNIVLLFMGLSFLEASGYMARAAFVIDKVMHRFGLHGKSFIPMITGFGCSIPAIMATRT
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHH
LKSRSDRLATIMTIPFMSCSAKLPVYVLLAGAFFPPAMAANVMFGIYLLGIMIGLWTAWL
HHHCCCCEEEEEEEHHHCCCCCCCCHHEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
LKSTVLKSDSEPFVMELPPYRWPTLTSVVFQARMKAVMYLKKAGTLILGAVIVIWAASNF
HHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
PRSSALDAELAQEKAKIEATAVAPELKAEQLQKLKARIDAGQLEYSLAGRSGKLLEPLIR
CCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHH
PLGFDWRIGISLVTGLAAKEVVVSTLGTIFSIGHAAGQTSLSQILRSDPSFSKATALSLM
HCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHH
VFVLLYIPCVASVGVMKKEVGAWKPVLLYSVYVLAVAWIASFITYHLALLWL
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Fe (II) [Periplasm] [C]

Specific reaction: Fe (II) [Periplasm] = Fe (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12949112 [H]