Click here to switch to the map view.

The map label for this gene is orn

Identifier: 21672814

GI number: 21672814

Start: 610369

End: 610923

Strand: Direct

Name: orn

Synonym: BUsg554

Alternate gene names: 21672814

Gene position: 610369-610923 (Clockwise)

Preceding gene: 21672801

Following gene: 21672815

Centisome position: 95.15

GC content: 23.24

Gene sequence:

>555_bases
ATGACTATTAATAATGAAAATCTTATTTGGATTGATTTGGAAATGACTGGATTGAATTCTGAAATACATCGAATTATTGA
GATTGCTACAGTAATTACAGATACAAAATTAAATATAATTTCAGAAGGTCCAGTTATTGCTATTCATCAAAAAGAAGAAC
ATATAGTAATAATGGATGAATGGAATACTAAAATACATAAAAAAAATGGATTAATAAAACGAGTACAAAAAAGTATATAT
AATGAATCAAAAGCTGAATCTAAAACTATATTCTTTTTAAAAAAATGGGTTCCTATTCAATCATCACCTATCTGTGGTAA
CAGTGTCTATCAAGATAGAAAGTTTTTAGCTCGATATATGCCAAATTTAGAAAACTATTTTCACTATCGATGTATAGATG
TTAGTACTATTAAAGAATTAGTAAATCGTTGGTGTCCTTCATTTAAAAAAATAAAAAAACAAAATCATACAGCATTAGAA
GATATTCATGAATCTATAATAGAATTAAATTTTTATAAAAAAATTTTTTTTGATACTATAAAATATAGTAAATAA

Upstream 100 bases:

>100_bases
ATATTAAAAACATTTATTTTTTATTGAGTTTTTATTATACTATATTCATTAATTTTTAACTAAAAAAATAGAATTAAAAA
AAATTTATTTATAAAAAATT

Downstream 100 bases:

>100_bases
CATTCTATTCTAATTAAAGTTATTTAAAGAATTTTTAAATAAAATCAATATTTTTTAAAAGAAAGCTTGATAAATATATC
TTATATATATAATATAAATA

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MTINNENLIWIDLEMTGLNSEIHRIIEIATVITDTKLNIISEGPVIAIHQKEEHIVIMDEWNTKIHKKNGLIKRVQKSIY
NESKAESKTIFFLKKWVPIQSSPICGNSVYQDRKFLARYMPNLENYFHYRCIDVSTIKELVNRWCPSFKKIKKQNHTALE
DIHESIIELNFYKKIFFDTIKYSK

Sequences:

>Translated_184_residues
MTINNENLIWIDLEMTGLNSEIHRIIEIATVITDTKLNIISEGPVIAIHQKEEHIVIMDEWNTKIHKKNGLIKRVQKSIY
NESKAESKTIFFLKKWVPIQSSPICGNSVYQDRKFLARYMPNLENYFHYRCIDVSTIKELVNRWCPSFKKIKKQNHTALE
DIHESIIELNFYKKIFFDTIKYSK
>Mature_183_residues
TINNENLIWIDLEMTGLNSEIHRIIEIATVITDTKLNIISEGPVIAIHQKEEHIVIMDEWNTKIHKKNGLIKRVQKSIYN
ESKAESKTIFFLKKWVPIQSSPICGNSVYQDRKFLARYMPNLENYFHYRCIDVSTIKELVNRWCPSFKKIKKQNHTALED
IHESIIELNFYKKIFFDTIKYSK

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=175, Percent_Identity=45.1428571428571, Blast_Score=161, Evalue=3e-40,
Organism=Escherichia coli, GI87082382, Length=178, Percent_Identity=54.4943820224719, Blast_Score=219, Evalue=8e-59,
Organism=Caenorhabditis elegans, GI17557752, Length=173, Percent_Identity=48.5549132947977, Blast_Score=166, Evalue=8e-42,
Organism=Saccharomyces cerevisiae, GI6323088, Length=181, Percent_Identity=34.8066298342541, Blast_Score=99, Evalue=3e-22,
Organism=Drosophila melanogaster, GI21355135, Length=176, Percent_Identity=44.3181818181818, Blast_Score=156, Evalue=9e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_BUCAP (Q8K909)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660881.1
- ProteinModelPortal:   Q8K909
- SMR:   Q8K909
- EnsemblBacteria:   EBBUCT00000000545
- GeneID:   1005637
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg554
- GeneTree:   EBGT00050000008108
- HOGENOM:   HBG448545
- OMA:   WNKGTHG
- ProtClustDB:   PRK05359
- BioCyc:   BAPH198804:BUSG554-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 21818; Mature: 21686

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: ACT_SITE 129-129

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTINNENLIWIDLEMTGLNSEIHRIIEIATVITDTKLNIISEGPVIAIHQKEEHIVIMDE
CEECCCCEEEEEEEEECCCHHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCEEEEEEC
WNTKIHKKNGLIKRVQKSIYNESKAESKTIFFLKKWVPIQSSPICGNSVYQDRKFLARYM
CCCEEHHCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHC
PNLENYFHYRCIDVSTIKELVNRWCPSFKKIKKQNHTALEDIHESIIELNFYKKIFFDTI
CCHHHHHEEEEECHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
KYSK
HCCC
>Mature Secondary Structure 
TINNENLIWIDLEMTGLNSEIHRIIEIATVITDTKLNIISEGPVIAIHQKEEHIVIMDE
EECCCCEEEEEEEEECCCHHHHHHHHHHHHHHCCCEEEECCCCEEEEEECCCEEEEEEC
WNTKIHKKNGLIKRVQKSIYNESKAESKTIFFLKKWVPIQSSPICGNSVYQDRKFLARYM
CCCEEHHCCCHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHC
PNLENYFHYRCIDVSTIKELVNRWCPSFKKIKKQNHTALEDIHESIIELNFYKKIFFDTI
CCHHHHHEEEEECHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
KYSK
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438