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The map label for this gene is argD

Identifier: 21672780

GI number: 21672780

Start: 568062

End: 569276

Strand: Reverse

Name: argD

Synonym: BUsg515

Alternate gene names: 21672780

Gene position: 569276-568062 (Counterclockwise)

Preceding gene: 21672782

Following gene: 21672779

Centisome position: 88.75

GC content: 29.88

Gene sequence:

>1215_bases
ATGATAGGAAAAATAAAATTAATTACACGAGATAGTTTTAATAAGTTAATTTTACCTGTTTATAATCCAGCATTTTTTAT
CCCAGTTAAAGGGAAAGGCAGTCGTCTTTGGGATCAAAAAGGAAAAGAATACATTGATTTTTCAGGCGGAATTGCTGTGA
CGTCATTAGGTCACTGCCACCCTGTATTAAATAAAGTTTTAAGACAACAAAGTAAAAAATTATGGCACATTAGTAATATT
TTTACAAATGAACCCGCTTTGCGTTTAGCTGATAAATTAATTTCGTCGAGTTTTGCCTCTCGTGTGTTTTTTGCGAATTC
AGGTGCTGAAGCAAATGAAGCAGCTTTTAAACTAGCTCGTTATTATTCATCTAAAATATACAATTTAAAAAAAAATAAGA
TTATATCTTTTTATAATTCATTTCATGGACGAACTTTTTTTACTGTTTCTGTAGGTGGACAAGCAAAATATTCTGATTTT
TTTGGTCCAAAACCTCCAGCAATTATGCATGCTAAATTTAATGAAATCAACAGTGTTAAAAGTATAATTGATGATAATAC
CTGTGCTGTAGTGATGGAACTTATTCAGGGAGAGGGAGGAATTGTACCAGCGGATGTTGCTTTTGTTAGAGAAATCAGAG
ATCTTTGTTATAAATATAATGCACTTTTAATTTTTGATGAAATTCAAACTGGAATAGGTAGAACTAGTAAATTATATGCA
TATGAACATTATGAGGTACAACCTGATATTTTAACTATTGCAAAGTCTTTAGGAAGCGGTTTTCCAATAAGTGCGACTTT
AACAACAAATGGAATTGCATCTGTAATAAAACCTGGTATTCATGGTACTACATATGGAGGTAATCCCCTTGCTTGTTCTA
TTGCGGAATCTGTTGTTAATATTGTTAATACAAAAAAATTTTTATTAGGTGTAGAAAAAAAATCAAAAAAAATTATTTCT
GAACTAAATATTATCAATAAACGTTTTGGACTGTTTACAGAAATACGAGGAAAAGGATTACTTATTGGTATTGTATTAAG
ACCAGAGCTTTCTGAAGAAATACATAATATTTTAAATGCTTTATTTTTAGAAGGTGTAATTGTTTTAACTGCAGGTAAAA
ATGTAATACGATTAGCTCCTTCATTAATTATTAGTAAGCGTGATATTGTTGAAGGAATGAAGCGTTTTTATTGTGCTTTA
GAAAAATGTTTATAG

Upstream 100 bases:

>100_bases
TAAATTTAACAAAATATAATGTATATTTTAACTTTATAAGTTTATCTTTTTTTAGATTTAAAAATTTTTATTTTTTAGTA
AAAATATTTTAGGAAAATAA

Downstream 100 bases:

>100_bases
AAAATAAAGTTTTAGAAAACTATATTTTTTTTTAAATAAGATAAAGACATTTATTTTTTATTTAATGACTAGGAGGTCTT
TGATTTTTCAATAAACGATT

Product: bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT; DapATase; Succinyldiaminopimelate transferase

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MIGKIKLITRDSFNKLILPVYNPAFFIPVKGKGSRLWDQKGKEYIDFSGGIAVTSLGHCHPVLNKVLRQQSKKLWHISNI
FTNEPALRLADKLISSSFASRVFFANSGAEANEAAFKLARYYSSKIYNLKKNKIISFYNSFHGRTFFTVSVGGQAKYSDF
FGPKPPAIMHAKFNEINSVKSIIDDNTCAVVMELIQGEGGIVPADVAFVREIRDLCYKYNALLIFDEIQTGIGRTSKLYA
YEHYEVQPDILTIAKSLGSGFPISATLTTNGIASVIKPGIHGTTYGGNPLACSIAESVVNIVNTKKFLLGVEKKSKKIIS
ELNIINKRFGLFTEIRGKGLLIGIVLRPELSEEIHNILNALFLEGVIVLTAGKNVIRLAPSLIISKRDIVEGMKRFYCAL
EKCL

Sequences:

>Translated_404_residues
MIGKIKLITRDSFNKLILPVYNPAFFIPVKGKGSRLWDQKGKEYIDFSGGIAVTSLGHCHPVLNKVLRQQSKKLWHISNI
FTNEPALRLADKLISSSFASRVFFANSGAEANEAAFKLARYYSSKIYNLKKNKIISFYNSFHGRTFFTVSVGGQAKYSDF
FGPKPPAIMHAKFNEINSVKSIIDDNTCAVVMELIQGEGGIVPADVAFVREIRDLCYKYNALLIFDEIQTGIGRTSKLYA
YEHYEVQPDILTIAKSLGSGFPISATLTTNGIASVIKPGIHGTTYGGNPLACSIAESVVNIVNTKKFLLGVEKKSKKIIS
ELNIINKRFGLFTEIRGKGLLIGIVLRPELSEEIHNILNALFLEGVIVLTAGKNVIRLAPSLIISKRDIVEGMKRFYCAL
EKCL
>Mature_404_residues
MIGKIKLITRDSFNKLILPVYNPAFFIPVKGKGSRLWDQKGKEYIDFSGGIAVTSLGHCHPVLNKVLRQQSKKLWHISNI
FTNEPALRLADKLISSSFASRVFFANSGAEANEAAFKLARYYSSKIYNLKKNKIISFYNSFHGRTFFTVSVGGQAKYSDF
FGPKPPAIMHAKFNEINSVKSIIDDNTCAVVMELIQGEGGIVPADVAFVREIRDLCYKYNALLIFDEIQTGIGRTSKLYA
YEHYEVQPDILTIAKSLGSGFPISATLTTNGIASVIKPGIHGTTYGGNPLACSIAESVVNIVNTKKFLLGVEKKSKKIIS
ELNIINKRFGLFTEIRGKGLLIGIVLRPELSEEIHNILNALFLEGVIVLTAGKNVIRLAPSLIISKRDIVEGMKRFYCAL
EKCL

Specific function: Involved in both the arginine and lysine biosynthetic pathways

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily

Homologues:

Organism=Homo sapiens, GI4557809, Length=379, Percent_Identity=32.9815303430079, Blast_Score=208, Evalue=9e-54,
Organism=Homo sapiens, GI13994255, Length=438, Percent_Identity=30.365296803653, Blast_Score=187, Evalue=1e-47,
Organism=Homo sapiens, GI284507298, Length=293, Percent_Identity=33.1058020477816, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI37574042, Length=418, Percent_Identity=25.8373205741627, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI226442709, Length=392, Percent_Identity=26.0204081632653, Blast_Score=124, Evalue=1e-28,
Organism=Homo sapiens, GI226442705, Length=418, Percent_Identity=24.8803827751196, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI24119277, Length=416, Percent_Identity=23.5576923076923, Blast_Score=119, Evalue=7e-27,
Organism=Homo sapiens, GI188536080, Length=418, Percent_Identity=23.2057416267943, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI38679950, Length=418, Percent_Identity=23.2057416267943, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI38679946, Length=418, Percent_Identity=23.2057416267943, Blast_Score=91, Evalue=3e-18,
Organism=Escherichia coli, GI1789759, Length=397, Percent_Identity=56.9269521410579, Blast_Score=496, Evalue=1e-141,
Organism=Escherichia coli, GI1788044, Length=394, Percent_Identity=55.8375634517767, Blast_Score=476, Evalue=1e-136,
Organism=Escherichia coli, GI145693181, Length=372, Percent_Identity=33.6021505376344, Blast_Score=204, Evalue=6e-54,
Organism=Escherichia coli, GI1789016, Length=397, Percent_Identity=31.4861460957179, Blast_Score=198, Evalue=4e-52,
Organism=Escherichia coli, GI1787560, Length=402, Percent_Identity=31.3432835820896, Blast_Score=180, Evalue=1e-46,
Organism=Escherichia coli, GI1786991, Length=401, Percent_Identity=30.1745635910224, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786349, Length=288, Percent_Identity=26.7361111111111, Blast_Score=102, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI25144271, Length=374, Percent_Identity=34.7593582887701, Blast_Score=224, Evalue=7e-59,
Organism=Caenorhabditis elegans, GI32564660, Length=413, Percent_Identity=30.7506053268765, Blast_Score=188, Evalue=3e-48,
Organism=Caenorhabditis elegans, GI25144274, Length=265, Percent_Identity=35.0943396226415, Blast_Score=164, Evalue=9e-41,
Organism=Caenorhabditis elegans, GI71992977, Length=419, Percent_Identity=28.1622911694511, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71981843, Length=165, Percent_Identity=30.3030303030303, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6324432, Length=394, Percent_Identity=39.0862944162437, Blast_Score=271, Evalue=2e-73,
Organism=Saccharomyces cerevisiae, GI6323470, Length=411, Percent_Identity=33.8199513381995, Blast_Score=223, Evalue=6e-59,
Organism=Saccharomyces cerevisiae, GI6324386, Length=359, Percent_Identity=29.8050139275766, Blast_Score=120, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6321456, Length=425, Percent_Identity=26.3529411764706, Blast_Score=102, Evalue=8e-23,
Organism=Drosophila melanogaster, GI21357415, Length=378, Percent_Identity=34.3915343915344, Blast_Score=219, Evalue=4e-57,
Organism=Drosophila melanogaster, GI28574759, Length=412, Percent_Identity=28.6407766990291, Blast_Score=186, Evalue=3e-47,
Organism=Drosophila melanogaster, GI161085790, Length=413, Percent_Identity=28.3292978208232, Blast_Score=185, Evalue=6e-47,
Organism=Drosophila melanogaster, GI21356575, Length=426, Percent_Identity=29.1079812206573, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI281366494, Length=431, Percent_Identity=24.3619489559165, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24667139, Length=431, Percent_Identity=24.3619489559165, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24667143, Length=431, Percent_Identity=24.3619489559165, Blast_Score=96, Evalue=3e-20,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): ARGD_BUCAP (P59086)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660847.1
- ProteinModelPortal:   P59086
- SMR:   P59086
- EnsemblBacteria:   EBBUCT00000000217
- GeneID:   1005656
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg515
- GeneTree:   EBGT00050000007756
- HOGENOM:   HBG725944
- OMA:   VKEGFGP
- ProtClustDB:   PRK05093
- BioCyc:   BAPH198804:BUSG515-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01107
- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- PANTHER:   PTHR11986
- PANTHER:   PTHR11986:SF19
- TIGRFAMs:   TIGR03246
- TIGRFAMs:   TIGR00707

Pfam domain/function: PF00202 Aminotran_3; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.11; =2.6.1.17

Molecular weight: Translated: 44737; Mature: 44737

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: BINDING 141-141 BINDING 144-144 BINDING 283-283 BINDING 284-284

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGKIKLITRDSFNKLILPVYNPAFFIPVKGKGSRLWDQKGKEYIDFSGGIAVTSLGHCH
CCCEEEEEEECCCCCEEEEEECCEEEEEECCCCCCCHHHCCCEEEECCCCEEEECCCCHH
PVLNKVLRQQSKKLWHISNIFTNEPALRLADKLISSSFASRVFFANSGAEANEAAFKLAR
HHHHHHHHHHHHCEEEHHHHHCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHH
YYSSKIYNLKKNKIISFYNSFHGRTFFTVSVGGQAKYSDFFGPKPPAIMHAKFNEINSVK
HHHHHHHCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECHHHHHHHH
SIIDDNTCAVVMELIQGEGGIVPADVAFVREIRDLCYKYNALLIFDEIQTGIGRTSKLYA
HHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEHHHHCCCCCCEEEE
YEHYEVQPDILTIAKSLGSGFPISATLTTNGIASVIKPGIHGTTYGGNPLACSIAESVVN
EECCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCCEEHHHHHHHHH
IVNTKKFLLGVEKKSKKIISELNIINKRFGLFTEIRGKGLLIGIVLRPELSEEIHNILNA
HHCCHHHHEECCHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEEECCCHHHHHHHHHHH
LFLEGVIVLTAGKNVIRLAPSLIISKRDIVEGMKRFYCALEKCL
HHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIGKIKLITRDSFNKLILPVYNPAFFIPVKGKGSRLWDQKGKEYIDFSGGIAVTSLGHCH
CCCEEEEEEECCCCCEEEEEECCEEEEEECCCCCCCHHHCCCEEEECCCCEEEECCCCHH
PVLNKVLRQQSKKLWHISNIFTNEPALRLADKLISSSFASRVFFANSGAEANEAAFKLAR
HHHHHHHHHHHHCEEEHHHHHCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHH
YYSSKIYNLKKNKIISFYNSFHGRTFFTVSVGGQAKYSDFFGPKPPAIMHAKFNEINSVK
HHHHHHHCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEECHHHHHHHH
SIIDDNTCAVVMELIQGEGGIVPADVAFVREIRDLCYKYNALLIFDEIQTGIGRTSKLYA
HHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCEEEEEEHHHHCCCCCCEEEE
YEHYEVQPDILTIAKSLGSGFPISATLTTNGIASVIKPGIHGTTYGGNPLACSIAESVVN
EECCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHCCCCCCCCCCCCCEEHHHHHHHHH
IVNTKKFLLGVEKKSKKIISELNIINKRFGLFTEIRGKGLLIGIVLRPELSEEIHNILNA
HHCCHHHHEECCHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEEEECCCHHHHHHHHHHH
LFLEGVIVLTAGKNVIRLAPSLIISKRDIVEGMKRFYCALEKCL
HHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12089438