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The map label for this gene is asd

Identifier: 21672698

GI number: 21672698

Start: 489884

End: 490999

Strand: Reverse

Name: asd

Synonym: BUsg433

Alternate gene names: 21672698

Gene position: 490999-489884 (Counterclockwise)

Preceding gene: 21672706

Following gene: 21672687

Centisome position: 76.54

GC content: 27.69

Gene sequence:

>1116_bases
ATGACGAAGTCTGTTGGAATAATTGGTTGGCGCGGAATGGTAGGATCAGTTTTATTAAAAAGAATGCAAGAAGAAAATGA
TTTTTCAAAAATTATTCCTTATTTTTTTTCAACGTCTCAATCTGGTCAAGATGGTCCTATTATAAATAATATTTTATCTA
AAAATTTAAAGGATGCATATAATATTAATTTATTACAGGAAATGGATATTATTATTACATGTCAAGGAAGTTCTTACACT
GAAAAAATTTATCCAAAATTGCGTAATAATAATTGGCAAGGTTATTGGATAGATGCTGCTTCTACATTACGAATGGAAAA
AGATGCTACAATTATATTAGATCCTGTTAATTTAAATGTTATAAATAATGCATTGGATAAAGGAATTAAAACTTTTGTAG
GTGGTAATTGTACTGTGAGTTTGATGTTAATGGCTTTAGGAGGGTTGTTTGTAAACAATTTAATAGATTGGGTTTTTGTA
TCTACTTATCAAGCAGCATCAGGAGCTGGTTCTCGTTATGTAATTGAATTATTAAAACAAATGGGTTCTTTATATAATGT
CGTTTCTAAAGATTTATTAGATAAATCTTATTCTGTTTTAGATATTGAAAAAAAAGTTACTCAAGAAAGTCGTAGTAAAA
ATTTTCCATTAGAAAATTTTTCTGTACCATTAGCAACTAGTTTAATACCATGGATAGATGTAGAAATGAAAAATGGTCAA
AGTCGAGAAGAGTGGAAAGGACAAGCTGAAACAAACAAAATTTTAAATTTGAAAAAAAAAGTATTAATTGACGGAACTTG
TGTTCGTATAAGTTCAATTCGATGTCATAGTCAGTCATTTTTAATTAAATTAAACAAAGATATTTCTCTAGAAAATATAA
AAAAAATAATTGTTAATCATAATCAATGGGTTGATGTTATTCCTAACAATATGCAAAAAACATTATGTAATTTAACTCCA
TCTGCGGTGACTGATACATTAAATATACCAATAGGTCGATTAAGAAAATTAAATATAGATGATCGATATCTTTCTGCTTT
TACTGTGGGAGATCAGTTGTTATGGGGTGCCGCTGAACCTTTAAGAAGAATGCTAAACTTATTAGTTAATATTTAA

Upstream 100 bases:

>100_bases
TAGTATTTATTTTCGGAGGACGGTAAGTTTTTACTTTAACTGAATAAGTTGTCAATTTTGATAAAAATTATTGTTAATTT
AAAAATCCGTATATTAATTA

Downstream 100 bases:

>100_bases
TTTATTTTTAATAATTCTTAATTATATAGTATATATTAATATACACACCCAGTGTGTATATTAATCTTTTGATTTTTTTA
CATAAATTGTATTGATTCAT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MTKSVGIIGWRGMVGSVLLKRMQEENDFSKIIPYFFSTSQSGQDGPIINNILSKNLKDAYNINLLQEMDIIITCQGSSYT
EKIYPKLRNNNWQGYWIDAASTLRMEKDATIILDPVNLNVINNALDKGIKTFVGGNCTVSLMLMALGGLFVNNLIDWVFV
STYQAASGAGSRYVIELLKQMGSLYNVVSKDLLDKSYSVLDIEKKVTQESRSKNFPLENFSVPLATSLIPWIDVEMKNGQ
SREEWKGQAETNKILNLKKKVLIDGTCVRISSIRCHSQSFLIKLNKDISLENIKKIIVNHNQWVDVIPNNMQKTLCNLTP
SAVTDTLNIPIGRLRKLNIDDRYLSAFTVGDQLLWGAAEPLRRMLNLLVNI

Sequences:

>Translated_371_residues
MTKSVGIIGWRGMVGSVLLKRMQEENDFSKIIPYFFSTSQSGQDGPIINNILSKNLKDAYNINLLQEMDIIITCQGSSYT
EKIYPKLRNNNWQGYWIDAASTLRMEKDATIILDPVNLNVINNALDKGIKTFVGGNCTVSLMLMALGGLFVNNLIDWVFV
STYQAASGAGSRYVIELLKQMGSLYNVVSKDLLDKSYSVLDIEKKVTQESRSKNFPLENFSVPLATSLIPWIDVEMKNGQ
SREEWKGQAETNKILNLKKKVLIDGTCVRISSIRCHSQSFLIKLNKDISLENIKKIIVNHNQWVDVIPNNMQKTLCNLTP
SAVTDTLNIPIGRLRKLNIDDRYLSAFTVGDQLLWGAAEPLRRMLNLLVNI
>Mature_370_residues
TKSVGIIGWRGMVGSVLLKRMQEENDFSKIIPYFFSTSQSGQDGPIINNILSKNLKDAYNINLLQEMDIIITCQGSSYTE
KIYPKLRNNNWQGYWIDAASTLRMEKDATIILDPVNLNVINNALDKGIKTFVGGNCTVSLMLMALGGLFVNNLIDWVFVS
TYQAASGAGSRYVIELLKQMGSLYNVVSKDLLDKSYSVLDIEKKVTQESRSKNFPLENFSVPLATSLIPWIDVEMKNGQS
REEWKGQAETNKILNLKKKVLIDGTCVRISSIRCHSQSFLIKLNKDISLENIKKIIVNHNQWVDVIPNNMQKTLCNLTPS
AVTDTLNIPIGRLRKLNIDDRYLSAFTVGDQLLWGAAEPLRRMLNLLVNI

Specific function: Second step in the common biosynthetic pathway leading from Asp to the cell wall precursor meso-diaminopimelate, to Lys, to Met, to Ile and to Thr. [C]

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1789841, Length=367, Percent_Identity=61.8528610354223, Blast_Score=494, Evalue=1e-141,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DHAS_BUCAP (Q8K9B5)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660765.1
- ProteinModelPortal:   Q8K9B5
- SMR:   Q8K9B5
- EnsemblBacteria:   EBBUCT00000000023
- GeneID:   1005553
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg433
- GeneTree:   EBGT00050000008194
- HOGENOM:   HBG289760
- OMA:   IDGLCVR
- ProtClustDB:   PRK06598
- BioCyc:   BAPH198804:BUSG433-MONOMER
- GO:   GO:0005737
- InterPro:   IPR000319
- InterPro:   IPR011534
- InterPro:   IPR012080
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280
- Gene3D:   G3DSA:3.40.50.720
- PIRSF:   PIRSF000148
- SMART:   SM00859
- TIGRFAMs:   TIGR01745

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC

EC number: =1.2.1.11

Molecular weight: Translated: 41786; Mature: 41655

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS01103 ASD

Important sites: ACT_SITE 137-137

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKSVGIIGWRGMVGSVLLKRMQEENDFSKIIPYFFSTSQSGQDGPIINNILSKNLKDAY
CCCCCEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHH
NINLLQEMDIIITCQGSSYTEKIYPKLRNNNWQGYWIDAASTLRMEKDATIILDPVNLNV
CCCEEEECCEEEEECCCCCHHHHHHHHCCCCCCEEEEECHHHEEECCCCEEEEECCCHHH
INNALDKGIKTFVGGNCTVSLMLMALGGLFVNNLIDWVFVSTYQAASGAGSRYVIELLKQ
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
MGSLYNVVSKDLLDKSYSVLDIEKKVTQESRSKNFPLENFSVPLATSLIPWIDVEMKNGQ
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCCCCCCHHHHCCCEEEEEECCCC
SREEWKGQAETNKILNLKKKVLIDGTCVRISSIRCHSQSFLIKLNKDISLENIKKIIVNH
CHHHHCCCHHHHHHHHHHHHEEECCCEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHCC
NQWVDVIPNNMQKTLCNLTPSAVTDTLNIPIGRLRKLNIDDRYLSAFTVGDQLLWGAAEP
CCEEEECCCHHHHHHHCCCHHHHHHCCCCCHHHEEECCCCHHHHHEEECCHHHHHCCHHH
LRRMLNLLVNI
HHHHHHHHHCC
>Mature Secondary Structure 
TKSVGIIGWRGMVGSVLLKRMQEENDFSKIIPYFFSTSQSGQDGPIINNILSKNLKDAY
CCCCEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHCCCHHH
NINLLQEMDIIITCQGSSYTEKIYPKLRNNNWQGYWIDAASTLRMEKDATIILDPVNLNV
CCCEEEECCEEEEECCCCCHHHHHHHHCCCCCCEEEEECHHHEEECCCCEEEEECCCHHH
INNALDKGIKTFVGGNCTVSLMLMALGGLFVNNLIDWVFVSTYQAASGAGSRYVIELLKQ
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
MGSLYNVVSKDLLDKSYSVLDIEKKVTQESRSKNFPLENFSVPLATSLIPWIDVEMKNGQ
HHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCCCCCCHHHHCCCEEEEEECCCC
SREEWKGQAETNKILNLKKKVLIDGTCVRISSIRCHSQSFLIKLNKDISLENIKKIIVNH
CHHHHCCCHHHHHHHHHHHHEEECCCEEEEEEEEECCCEEEEEECCCCCHHHHHHHHHCC
NQWVDVIPNNMQKTLCNLTPSAVTDTLNIPIGRLRKLNIDDRYLSAFTVGDQLLWGAAEP
CCEEEECCCHHHHHHHCCCHHHHHHCCCCCHHHEEECCCCHHHHHEEECCHHHHHCCHHH
LRRMLNLLVNI
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12089438