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The map label for this gene is obgE

Identifier: 21672650

GI number: 21672650

Start: 428639

End: 429640

Strand: Direct

Name: obgE

Synonym: BUsg376

Alternate gene names: 21672650

Gene position: 428639-429640 (Clockwise)

Preceding gene: 21672649

Following gene: 21672653

Centisome position: 66.82

GC content: 27.94

Gene sequence:

>1002_bases
ATGAAATTTATTGATCAAACAATAATTCAAGTTATTGCTGGGAATGGTGGAAATGGATGTGTTAATTTTAGAAGAGAAAA
ATACATTCCTAAAGGTGGTCCAGATGGTGGAGATGGTGGGGATGGTGGAAACGTTTGGTTACAATCTGATAACAATTTAA
ATACTCTAATTGATCTTAGATTTAAAAAAACATTTCAAGCTCCTCACGGAGAAAATGGATCTGGAAAAAATTGTTCTGGT
AAAAAGGGAAGTGATATAAAAATATATGTTCCTGTTGGTACAAAAATTATCAATTATCAAACACGTGAAATAATAGGTGA
TTTAATTAAGCATAAGCAAAAAATATTAATTGCCAAAGGAGGTTGGCACGGATTAGGAAATACTAGATTTAAATCTTCAA
TAAATAGAACACCAAGACAAAGAACACTTGGATCAGTAGGAGAAAAACGTGATATACAATTGGAATTAATTTTAATAGCT
GATGTAGGGACGTTAGGTATGCCAAACGCTGGAAAATCTACTTTAGTAAAAAGTATATCTGGTGCTAAAACAAAAATCGC
AAACTATCCGTTTACTACATTAAATCCTGTTTTAGGAAGTGTTAATACAGAAGGTAAAAAATTTATTATAGCTGATATTC
CTGGAATAATGCAAAATGCATCTCAAGGATTTGGTTTAGGTGTGCGGTTTTTAAAACATTTAGAAAGATGTAAAATATTG
CTTCACATTGTTGATTTATGTCCTACAGATCATTCTAATCCTGTAGAAAATATAAGAATTATTTTAAATGAATTAAAAAA
ATATAATACAAGTTTATATAATAAACCAAGATGGTTAATTCTTAATAAAATTGATTTAATAAAATCTTCGGAAATAAAAA
AAATTATTGATAAAATTAAAAATTTTTTAAAAGTAGAAGAAAGGTTTTATTTAATCTCTTCGATTAAGAAAATAGGTGTT
AAAAAACTATGTTCTGACATAGCATTTTACTTGCAAAAATAG

Upstream 100 bases:

>100_bases
CCCCTTTTTAAATAAGGAGGGGTATTCTTTTCTTAAACTTAAGAAATAAAATATTAAAAATACATAGTAAATAATTTTTT
TAAAAAATAAAGAATAAAAA

Downstream 100 bases:

>100_bases
CAATTTTTTCTTTTGACTTTTTAATTTAAAATAAAAATTTTTACAATTATGAAAACACAAAAAAGAACTCGGTTTATTAT
AAAAACCAAGTTCTTTAAAA

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MKFIDQTIIQVIAGNGGNGCVNFRREKYIPKGGPDGGDGGDGGNVWLQSDNNLNTLIDLRFKKTFQAPHGENGSGKNCSG
KKGSDIKIYVPVGTKIINYQTREIIGDLIKHKQKILIAKGGWHGLGNTRFKSSINRTPRQRTLGSVGEKRDIQLELILIA
DVGTLGMPNAGKSTLVKSISGAKTKIANYPFTTLNPVLGSVNTEGKKFIIADIPGIMQNASQGFGLGVRFLKHLERCKIL
LHIVDLCPTDHSNPVENIRIILNELKKYNTSLYNKPRWLILNKIDLIKSSEIKKIIDKIKNFLKVEERFYLISSIKKIGV
KKLCSDIAFYLQK

Sequences:

>Translated_333_residues
MKFIDQTIIQVIAGNGGNGCVNFRREKYIPKGGPDGGDGGDGGNVWLQSDNNLNTLIDLRFKKTFQAPHGENGSGKNCSG
KKGSDIKIYVPVGTKIINYQTREIIGDLIKHKQKILIAKGGWHGLGNTRFKSSINRTPRQRTLGSVGEKRDIQLELILIA
DVGTLGMPNAGKSTLVKSISGAKTKIANYPFTTLNPVLGSVNTEGKKFIIADIPGIMQNASQGFGLGVRFLKHLERCKIL
LHIVDLCPTDHSNPVENIRIILNELKKYNTSLYNKPRWLILNKIDLIKSSEIKKIIDKIKNFLKVEERFYLISSIKKIGV
KKLCSDIAFYLQK
>Mature_333_residues
MKFIDQTIIQVIAGNGGNGCVNFRREKYIPKGGPDGGDGGDGGNVWLQSDNNLNTLIDLRFKKTFQAPHGENGSGKNCSG
KKGSDIKIYVPVGTKIINYQTREIIGDLIKHKQKILIAKGGWHGLGNTRFKSSINRTPRQRTLGSVGEKRDIQLELILIA
DVGTLGMPNAGKSTLVKSISGAKTKIANYPFTTLNPVLGSVNTEGKKFIIADIPGIMQNASQGFGLGVRFLKHLERCKIL
LHIVDLCPTDHSNPVENIRIILNELKKYNTSLYNKPRWLILNKIDLIKSSEIKKIIDKIKNFLKVEERFYLISSIKKIGV
KKLCSDIAFYLQK

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=305, Percent_Identity=39.344262295082, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI111955139, Length=297, Percent_Identity=37.3737373737374, Blast_Score=154, Evalue=2e-37,
Organism=Homo sapiens, GI111955063, Length=185, Percent_Identity=34.5945945945946, Blast_Score=101, Evalue=8e-22,
Organism=Homo sapiens, GI4758796, Length=117, Percent_Identity=34.1880341880342, Blast_Score=75, Evalue=1e-13,
Organism=Escherichia coli, GI1789574, Length=332, Percent_Identity=59.0361445783133, Blast_Score=397, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17508313, Length=285, Percent_Identity=37.5438596491228, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17552324, Length=310, Percent_Identity=32.258064516129, Blast_Score=138, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=29.4964028776978, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17555344, Length=117, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321962, Length=188, Percent_Identity=36.7021276595745, Blast_Score=106, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6319281, Length=125, Percent_Identity=32.8, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321612, Length=112, Percent_Identity=35.7142857142857, Blast_Score=70, Evalue=4e-13,
Organism=Drosophila melanogaster, GI20129375, Length=285, Percent_Identity=39.2982456140351, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24585318, Length=237, Percent_Identity=40.5063291139241, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI17981711, Length=117, Percent_Identity=31.6239316239316, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_BUCAP (Q8K9G1)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660717.1
- ProteinModelPortal:   Q8K9G1
- SMR:   Q8K9G1
- EnsemblBacteria:   EBBUCT00000000468
- GeneID:   1005781
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg376
- GeneTree:   EBGT00050000007775
- HOGENOM:   HBG716038
- OMA:   LIDYRFN
- ProtClustDB:   PRK12299
- BioCyc:   BAPH198804:BUSG376-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 36942; Mature: 36942

Theoretical pI: Translated: 10.51; Mature: 10.51

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFIDQTIIQVIAGNGGNGCVNFRREKYIPKGGPDGGDGGDGGNVWLQSDNNLNTLIDLR
CCHHHHHHHHHHCCCCCCCEECCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEE
FKKTFQAPHGENGSGKNCSGKKGSDIKIYVPVGTKIINYQTREIIGDLIKHKQKILIAKG
EHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEECHHHHHHHHHHHHCCCEEEEECC
GWHGLGNTRFKSSINRTPRQRTLGSVGEKRDIQLELILIADVGTLGMPNAGKSTLVKSIS
CCCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHC
GAKTKIANYPFTTLNPVLGSVNTEGKKFIIADIPGIMQNASQGFGLGVRFLKHLERCKIL
CCHHHHCCCCCHHHHHHHCCCCCCCCEEEEEECCHHHHHCCCCCCHHHHHHHHHHHHHHH
LHIVDLCPTDHSNPVENIRIILNELKKYNTSLYNKPRWLILNKIDLIKSSEIKKIIDKIK
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHH
NFLKVEERFYLISSIKKIGVKKLCSDIAFYLQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKFIDQTIIQVIAGNGGNGCVNFRREKYIPKGGPDGGDGGDGGNVWLQSDNNLNTLIDLR
CCHHHHHHHHHHCCCCCCCEECCHHHHCCCCCCCCCCCCCCCCEEEEECCCCCCEEEEEE
FKKTFQAPHGENGSGKNCSGKKGSDIKIYVPVGTKIINYQTREIIGDLIKHKQKILIAKG
EHHHCCCCCCCCCCCCCCCCCCCCCEEEEEECCCEEECHHHHHHHHHHHHCCCEEEEECC
GWHGLGNTRFKSSINRTPRQRTLGSVGEKRDIQLELILIADVGTLGMPNAGKSTLVKSIS
CCCCCCCHHHHHHHCCCHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCHHHHHHHHC
GAKTKIANYPFTTLNPVLGSVNTEGKKFIIADIPGIMQNASQGFGLGVRFLKHLERCKIL
CCHHHHCCCCCHHHHHHHCCCCCCCCEEEEEECCHHHHHCCCCCCHHHHHHHHHHHHHHH
LHIVDLCPTDHSNPVENIRIILNELKKYNTSLYNKPRWLILNKIDLIKSSEIKKIIDKIK
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHH
NFLKVEERFYLISSIKKIGVKKLCSDIAFYLQK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438