Click here to switch to the map view.

The map label for this gene is znuB

Identifier: 21672583

GI number: 21672583

Start: 351718

End: 352503

Strand: Reverse

Name: znuB

Synonym: BUsg307

Alternate gene names: 21672583

Gene position: 352503-351718 (Counterclockwise)

Preceding gene: 21672584

Following gene: 21672579

Centisome position: 54.95

GC content: 25.83

Gene sequence:

>786_bases
ATGTTTGAATTAATTTATCCAGGATGGTTAGCAGGTATTTTATTATCTTTTGCAACTGGACCTCTAGGTTCTTTTATTAT
TTGGCGTCGTATATCGTCTTTTGGTGACACATTATCTCATTCTTCTATACTCGGCTTAGCTATATCCATTTTATTTCAAA
TTGATTCCTTCTATACAGAATTATTTTTTATGAGCTTTCTTGCTATTATATTAGTATGGATGGAACAATTATTATCAGTT
TCATTAGAAACAATATTAAGTATAATATCGCATAGTTCATTATCTTTAGGAATAATTTGTATTAGCTTGATGTCTACTTC
TCATCATATAGATCTTAGTAATTATTTATTTGGTGATTTATTACTTGTAACGGTATTTGATTTATGTATTATTGCTTTAG
GAAGTTTAATTGTTTTAACTATTTTATTTTTTCGTTGGAATTCTATTTTATTACTGACAGTTAATGAAGAATTAGCTCAA
ATTGATGGTGTTAATATTTTTTATGCACGTTTAACTTTAATGTTAACTACTGCTATATGTATTTCTATTGCTATTAAGTT
TGTTGGAGTACTATTAATCACTTCATTACTAATTATTCCTCCTGCAACTGCGCAAATTTTTTCTAATTCTCCAGAAAAAA
CGATTGGATTTTCAATATTAATAAGTATTATTTCAGTTACAGGTGGAATTTTTTTATCTTTTTTTTACAACGTTCCAACT
AGTCCATCTATTGTTTTATTTTCTTCTTGTGTTTACTTATTAAGTAATATAAAAAAATTAATATAA

Upstream 100 bases:

>100_bases
TATTTCTATATTTGGTTTAAAACATATAAGGGAATTAGCAATTTATCAACATAATCATGATCATGTACATCAATATTAAA
ATTATAGAGTATTTTTTATC

Downstream 100 bases:

>100_bases
AAATTTTTATTTCTTTAATATATTTATACCTAACTCATTTAAAATTGATTTTTTTAATTTACTAGGAGAGTCAGTCATTA
GGCAATTTGCTGACGTTGTT

Product: high-affinity zinc uptake system membrane protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MFELIYPGWLAGILLSFATGPLGSFIIWRRISSFGDTLSHSSILGLAISILFQIDSFYTELFFMSFLAIILVWMEQLLSV
SLETILSIISHSSLSLGIICISLMSTSHHIDLSNYLFGDLLLVTVFDLCIIALGSLIVLTILFFRWNSILLLTVNEELAQ
IDGVNIFYARLTLMLTTAICISIAIKFVGVLLITSLLIIPPATAQIFSNSPEKTIGFSILISIISVTGGIFLSFFYNVPT
SPSIVLFSSCVYLLSNIKKLI

Sequences:

>Translated_261_residues
MFELIYPGWLAGILLSFATGPLGSFIIWRRISSFGDTLSHSSILGLAISILFQIDSFYTELFFMSFLAIILVWMEQLLSV
SLETILSIISHSSLSLGIICISLMSTSHHIDLSNYLFGDLLLVTVFDLCIIALGSLIVLTILFFRWNSILLLTVNEELAQ
IDGVNIFYARLTLMLTTAICISIAIKFVGVLLITSLLIIPPATAQIFSNSPEKTIGFSILISIISVTGGIFLSFFYNVPT
SPSIVLFSSCVYLLSNIKKLI
>Mature_261_residues
MFELIYPGWLAGILLSFATGPLGSFIIWRRISSFGDTLSHSSILGLAISILFQIDSFYTELFFMSFLAIILVWMEQLLSV
SLETILSIISHSSLSLGIICISLMSTSHHIDLSNYLFGDLLLVTVFDLCIIALGSLIVLTILFFRWNSILLLTVNEELAQ
IDGVNIFYARLTLMLTTAICISIAIKFVGVLLITSLLIIPPATAQIFSNSPEKTIGFSILISIISVTGGIFLSFFYNVPT
SPSIVLFSSCVYLLSNIKKLI

Specific function: Involved in the high-affinity zinc uptake transport system

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family

Homologues:

Organism=Escherichia coli, GI1788166, Length=259, Percent_Identity=49.034749034749, Blast_Score=262, Evalue=1e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ZNUB_BUCAP (Q8K9M7)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660650.1
- ProteinModelPortal:   Q8K9M7
- EnsemblBacteria:   EBBUCT00000000273
- GeneID:   1005511
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg307
- GeneTree:   EBGT00050000007953
- HOGENOM:   HBG733179
- OMA:   GDSISHA
- ProtClustDB:   CLSK315880
- BioCyc:   BAPH198804:BUSG307-MONOMER
- InterPro:   IPR001626

Pfam domain/function: PF00950 ABC-3

EC number: NA

Molecular weight: Translated: 28753; Mature: 28753

Theoretical pI: Translated: 5.05; Mature: 5.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xc52d67c)-; HASH(0xbf153a0)-; HASH(0xc32ca28)-; HASH(0x404609a4)-; HASH(0xc68b408)-; HASH(0xb8ba8a0)-; HASH(0xb0e008c)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFELIYPGWLAGILLSFATGPLGSFIIWRRISSFGDTLSHSSILGLAISILFQIDSFYTE
CCCEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFFMSFLAIILVWMEQLLSVSLETILSIISHSSLSLGIICISLMSTSHHIDLSNYLFGDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
LLVTVFDLCIIALGSLIVLTILFFRWNSILLLTVNEELAQIDGVNIFYARLTLMLTTAIC
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHCCCHHHHHHHHHHHHHHHH
ISIAIKFVGVLLITSLLIIPPATAQIFSNSPEKTIGFSILISIISVTGGIFLSFFYNVPT
HHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SPSIVLFSSCVYLLSNIKKLI
CCHHHHHHHHHHHHHHHHHHH
>Mature Secondary Structure
MFELIYPGWLAGILLSFATGPLGSFIIWRRISSFGDTLSHSSILGLAISILFQIDSFYTE
CCCEECHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LFFMSFLAIILVWMEQLLSVSLETILSIISHSSLSLGIICISLMSTSHHIDLSNYLFGDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCHHHHHHHHH
LLVTVFDLCIIALGSLIVLTILFFRWNSILLLTVNEELAQIDGVNIFYARLTLMLTTAIC
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECHHHHHHCCCHHHHHHHHHHHHHHHH
ISIAIKFVGVLLITSLLIIPPATAQIFSNSPEKTIGFSILISIISVTGGIFLSFFYNVPT
HHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SPSIVLFSSCVYLLSNIKKLI
CCHHHHHHHHHHHHHHHHHHH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12089438