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The map label for this gene is ahpC [C]

Identifier: 21672464

GI number: 21672464

Start: 199918

End: 200514

Strand: Reverse

Name: ahpC [C]

Synonym: BUsg176

Alternate gene names: 21672464

Gene position: 200514-199918 (Counterclockwise)

Preceding gene: 21672465

Following gene: 21672462

Centisome position: 31.26

GC content: 28.64

Gene sequence:

>597_bases
ATGACTTTAGTAACACAAAAAGCGCCAAATTTTATAGCACCAGCAATTTTAAAAAATGGTAAAATCATGAATAATTTTGA
TTTAAAAAAATATTCTAATGGTCAAATAACCGTATTGTTTTTTTGGCCTATGGATTTTACTTTTGTTTGTCCTTCTGAAA
TCATCGAATTTAATAAAACCTTTGAAGCTTTTGAAAAAAGAAATGTAAAAATTGTTGGTGTTTCTATTGATAGTGTTTTT
GTTCATCAAGCATGGCAAAATACCTTTCCTGAAAATGGAGGAATTGGAAAAATAAAATTTCCTATGGTTTCTGATATAAA
ACATGAAATTCAAAAATCTTATCATATAGAACATCCGGAATTAAATATAGCATTAAGAGCCTCATTCTTAATTGATGAAA
ATTGGATTATACGTCATCAAGTTGTTAATGATCTTCCTTTCGGACGTAACATTGATGAAATGATACGGATGATAGACGCT
TTAAATTTTCATAATAAATACGGAGAAGTATGTCCTGTAAATTGGAAGCATGGACAAGAGGGGATGAAAGCTTCTCAAGA
GGGAGTTTCTTCATATTTAAAAAAATATTTTTCATAA

Upstream 100 bases:

>100_bases
ATAAAAATTAATTTTACACATAATTATTTATCAAAATAAATTCTTTTTTTTATTAAGGAACACATATCTTATTCTATTTT
TTTAATTAAAAGGAAAAAAA

Downstream 100 bases:

>100_bases
AAATTAACAGATAATTTTAAAGTCAGCAAAAAAAAATATGCTGGCTTTATTTTTAATTTAAAAATAAATTATTAACAACT
TTGATTTAAATACTAAACAT

Product: alkyl hydroperoxide reductase subunit C

Products: NA

Alternate protein names: Thioredoxin reductase

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MTLVTQKAPNFIAPAILKNGKIMNNFDLKKYSNGQITVLFFWPMDFTFVCPSEIIEFNKTFEAFEKRNVKIVGVSIDSVF
VHQAWQNTFPENGGIGKIKFPMVSDIKHEIQKSYHIEHPELNIALRASFLIDENWIIRHQVVNDLPFGRNIDEMIRMIDA
LNFHNKYGEVCPVNWKHGQEGMKASQEGVSSYLKKYFS

Sequences:

>Translated_198_residues
MTLVTQKAPNFIAPAILKNGKIMNNFDLKKYSNGQITVLFFWPMDFTFVCPSEIIEFNKTFEAFEKRNVKIVGVSIDSVF
VHQAWQNTFPENGGIGKIKFPMVSDIKHEIQKSYHIEHPELNIALRASFLIDENWIIRHQVVNDLPFGRNIDEMIRMIDA
LNFHNKYGEVCPVNWKHGQEGMKASQEGVSSYLKKYFS
>Mature_197_residues
TLVTQKAPNFIAPAILKNGKIMNNFDLKKYSNGQITVLFFWPMDFTFVCPSEIIEFNKTFEAFEKRNVKIVGVSIDSVFV
HQAWQNTFPENGGIGKIKFPMVSDIKHEIQKSYHIEHPELNIALRASFLIDENWIIRHQVVNDLPFGRNIDEMIRMIDAL
NFHNKYGEVCPVNWKHGQEGMKASQEGVSSYLKKYFS

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain

Homologues:

Organism=Homo sapiens, GI4505591, Length=192, Percent_Identity=41.6666666666667, Blast_Score=172, Evalue=1e-43,
Organism=Homo sapiens, GI32455266, Length=192, Percent_Identity=41.6666666666667, Blast_Score=172, Evalue=1e-43,
Organism=Homo sapiens, GI32455264, Length=192, Percent_Identity=41.6666666666667, Blast_Score=172, Evalue=1e-43,
Organism=Homo sapiens, GI32189392, Length=193, Percent_Identity=37.8238341968912, Blast_Score=162, Evalue=2e-40,
Organism=Homo sapiens, GI5453549, Length=192, Percent_Identity=39.5833333333333, Blast_Score=160, Evalue=9e-40,
Organism=Homo sapiens, GI5802974, Length=192, Percent_Identity=40.1041666666667, Blast_Score=157, Evalue=5e-39,
Organism=Homo sapiens, GI32483377, Length=191, Percent_Identity=38.7434554973822, Blast_Score=153, Evalue=1e-37,
Organism=Homo sapiens, GI4758638, Length=154, Percent_Identity=29.8701298701299, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI33188454, Length=95, Percent_Identity=40, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1786822, Length=186, Percent_Identity=32.258064516129, Blast_Score=106, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI193204376, Length=195, Percent_Identity=37.9487179487179, Blast_Score=154, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI32565831, Length=195, Percent_Identity=37.9487179487179, Blast_Score=154, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17554494, Length=190, Percent_Identity=37.3684210526316, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25153706, Length=180, Percent_Identity=28.3333333333333, Blast_Score=80, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6323613, Length=191, Percent_Identity=36.6492146596859, Blast_Score=145, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6320661, Length=191, Percent_Identity=35.0785340314136, Blast_Score=135, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6319407, Length=185, Percent_Identity=34.0540540540541, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI17157991, Length=194, Percent_Identity=39.6907216494845, Blast_Score=164, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24641739, Length=194, Percent_Identity=39.6907216494845, Blast_Score=164, Evalue=5e-41,
Organism=Drosophila melanogaster, GI17738015, Length=195, Percent_Identity=41.025641025641, Blast_Score=163, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24656348, Length=194, Percent_Identity=38.659793814433, Blast_Score=162, Evalue=1e-40,
Organism=Drosophila melanogaster, GI17864676, Length=194, Percent_Identity=38.659793814433, Blast_Score=162, Evalue=1e-40,
Organism=Drosophila melanogaster, GI21357347, Length=194, Percent_Identity=38.659793814433, Blast_Score=159, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24581278, Length=180, Percent_Identity=28.8888888888889, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17975518, Length=154, Percent_Identity=29.8701298701299, Blast_Score=73, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24652436, Length=154, Percent_Identity=29.2207792207792, Blast_Score=72, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24652434, Length=154, Percent_Identity=29.2207792207792, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): TSAA_BUCAP (Q8K9W0)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660531.1
- ProteinModelPortal:   Q8K9W0
- SMR:   Q8K9W0
- EnsemblBacteria:   EBBUCT00000000226
- GeneID:   1005373
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg176
- GeneTree:   EBGT00050000008040
- HOGENOM:   HBG493509
- OMA:   NFHEKNG
- ProtClustDB:   CLSK315734
- BioCyc:   BAPH198804:BUSG176-MONOMER
- GO:   GO:0005737
- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335
- Gene3D:   G3DSA:3.40.30.10

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA; SSF52833 Thiordxn-like_fd

EC number: =1.11.1.15

Molecular weight: Translated: 22917; Mature: 22786

Theoretical pI: Translated: 8.24; Mature: 8.24

Prosite motif: PS51352 THIOREDOXIN_2

Important sites: ACT_SITE 50-50

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVTQKAPNFIAPAILKNGKIMNNFDLKKYSNGQITVLFFWPMDFTFVCPSEIIEFNKT
CCCCCCCCCCHHHHHHHCCCEEECCCCCCEECCCCEEEEEEECCCEEEECHHHHHHHHHH
FEAFEKRNVKIVGVSIDSVFVHQAWQNTFPENGGIGKIKFPMVSDIKHEIQKSYHIEHPE
HHHHHHCCEEEEEEEHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCC
LNIALRASFLIDENWIIRHQVVNDLPFGRNIDEMIRMIDALNFHNKYGEVCPVNWKHGQE
EEEEEEEEEEECCCEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
GMKASQEGVSSYLKKYFS
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLVTQKAPNFIAPAILKNGKIMNNFDLKKYSNGQITVLFFWPMDFTFVCPSEIIEFNKT
CCCCCCCCCHHHHHHHCCCEEECCCCCCEECCCCEEEEEEECCCEEEECHHHHHHHHHH
FEAFEKRNVKIVGVSIDSVFVHQAWQNTFPENGGIGKIKFPMVSDIKHEIQKSYHIEHPE
HHHHHHCCEEEEEEEHHHHHHHHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHCCCCCC
LNIALRASFLIDENWIIRHQVVNDLPFGRNIDEMIRMIDALNFHNKYGEVCPVNWKHGQE
EEEEEEEEEEECCCEEEHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCH
GMKASQEGVSSYLKKYFS
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438