| Definition | Buchnera aphidicola str. Sg (Schizaphis graminum), complete genome. |
|---|---|
| Accession | NC_004061 |
| Length | 641,454 |
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The map label for this gene is nrdA
Identifier: 21672461
GI number: 21672461
Start: 193963
End: 196254
Strand: Reverse
Name: nrdA
Synonym: BUsg173
Alternate gene names: 21672461
Gene position: 196254-193963 (Counterclockwise)
Preceding gene: 21672462
Following gene: 21672460
Centisome position: 30.6
GC content: 28.71
Gene sequence:
>2292_bases ATGAAAAATAGTTTATTTGTGACAAAACGCAATGGAAAAAAAGAAAAAATAAATTTAGATAAAATACACAAAGTTTTAAA TTGGGCAGCGAAAGGATTAGAAAATATATCTGTTTCCCAAGTTGAATTACGTTCACGTATTCAGTTTTATAATAATATTA GCACTGTGAATATACATGAAACAATCATTAAAGCTGCAGCAGATTTAATTTCTGAAAATACACCTGATTATCAATATATG GCCGCAAGACTTGCAATTTTTCATCTTAGAAAAAAAGCTTATGGTCAGTTTGAACCGCCAAATCTTTATTATCATGTAAA AAAAATGGTTCAGTTGGGAAAATATGACGAAAAATTACTACAAAATTATTCTTTTGAAGAATATGTTGAAATGAATTCAT TTGTCGATCATCGGCGCGATATGAACTTTTCTTATGCAGCAGTAAAACAGTTAGAAGCAAAATATCTTCTACAAAATCGC GTTACTGGACAAATATATGAAAGTGCACAATTCTTATATATCTTAATATCCGCATGCTTATTTTCTAAATACGAAAAAAA AGTTCGTATGAATTATATTCAACGTTTTTATAACGCAATTTCTACTTTTAAAATATCTTTACCTACACCAATAATGTCAG GAGTAAGAACGCCAACTCGTCAATTTAGTTCTTGTGTACTAATTGAGTGTGCAGATAATTTAAATTCTATTAATGCCACA ACTAGTGCAATTGTAAAATACGTTTCTCAGAGAGCAGGAATAGGTATTAATGCTGGTCAAATTCGGGCTTTGGGGAGTCC TATTAGAAATGGAGAAGCATTTCATACTGGATGCATTCCTTTTTATAAGCACTTCCAAAGCGCCGTAAAATCTTGTTCTC AAGGTGGAGTTAGAGGAGGAGCAGCAACTGTTTTTTACCCAATATGGCATCTAGAAATTGAAAGTTTATTAGTTTTGAAA AATAATCGAGGCATTGAAGAAAATAGAGTACGTCATCTTGATTATGCTGTACAAATTAATAAATTAATGTATCAAAGAAT GCTACTAGGGCAAAAAATTACACTGTTTAGTCCTTCCGACGTTCCTAAATTATATGAATTTTTTTTCTCTGATCAAAAAA AATTTAAAGAAATTTACATTAAATATGAAAAAAATAGAAATATAAGAAAAAAAAGTATTAATGCAATTGATTTATTTTGT TTAATTATGCGAGAAAGAGCATCAACTGGACGAATTTACATACAACATGTAGATCATTGTAATTCACATAGTGCATTTAA TTCTAAATTAGCAACAATAAGACAATCTAACTTATGTCTAGAAATTACATTGCCTACAAAACCATTAAATAACATTGATG ATAAAAATGGAGAAATTGCACTTTGTACTTTATCTGCTCTTAATCTAGGTTTAATTAATGACTTACACGATCTTAAAGAA TTATCTACATTATCTGTACGAGCATTAGATGAAATATTAGAATATCAAAACTATCCAGTAGTATGCGCGAAAAAATCAGC TATTTCAAGACGTTCTTTAGGAATTGGTGTAATTAATTTCGCATATTATTTAGCTAAAAATAAAGTACGTTATTCAGACG GTAGCGCAAAAAATTTAACACATAAAACTTTTGAAGCAATACAGTATTATTTACTAAAAGCTTCTTGCGAGTTAGCTAAA GAAAAAGGATCCTGTTCATTATTCAATCAAACTAATTACTATTTAGGTAAATTTCCCATTGATACATATAAAAAAGATAT AGACTCAATATGTAATGAACCATTGCATTTAAATTGGAATTTATTACGTAAAAAAATTAAAAAATATGGATTAAGAAATT CTACCTTATCCGCTTTAATGCCTTCAGAAACTTCGTCTCAAATATCTAATGCTACTAATGGTATTGAACCTCCAAGAGGT TTTATCAGTATAAAATCTTCAAAAGATGGAATGCTGAGACAAGTTGTTCCAGAATATAAAAAATTAAAATCTGAATATGA GTTACTTTGGGAGATACCAAATAATATAGGATATTTAGAACTTGTTGCAATTATGCAGAAGTTTGTTGATCAATCTATTT CAGCAAATACTAATTATGATCCAAAACGATTTTTAAATGAAAAAATACCTATGAAACAGCTTATATATGATTTACTTGTA GCTTATAAACTGGGAATCAAAACACTTTATTATCAAAATACTCGTGATGGTGCTGAAGATAATCAAAATTTGAATAAATC TATTGAAAACATAAAAGAAGATAATTGTACAAGTGGCTCTTGTACGATATAA
Upstream 100 bases:
>100_bases AAATATTTTAATAAAAAACCATTTTAACTAAAAGAGTTTTTATACTACATTTCAAAAACAATATTTTTATATATATTTTT TTAAATAGGTTAATTTAAAT
Downstream 100 bases:
>100_bases TAATGATATAAATTTAATTAAAAATTAAAAATTTTTCGGATATAACATAAGTGTCTTATACAACTTTTTCAAAAAAGAAA AACAATCAACTTAAAGAACC
Product: ribonucleotide-diphosphate reductase subunit alpha
Products: NA
Alternate protein names: Ribonucleotide reductase
Number of amino acids: Translated: 763; Mature: 763
Protein sequence:
>763_residues MKNSLFVTKRNGKKEKINLDKIHKVLNWAAKGLENISVSQVELRSRIQFYNNISTVNIHETIIKAAADLISENTPDYQYM AARLAIFHLRKKAYGQFEPPNLYYHVKKMVQLGKYDEKLLQNYSFEEYVEMNSFVDHRRDMNFSYAAVKQLEAKYLLQNR VTGQIYESAQFLYILISACLFSKYEKKVRMNYIQRFYNAISTFKISLPTPIMSGVRTPTRQFSSCVLIECADNLNSINAT TSAIVKYVSQRAGIGINAGQIRALGSPIRNGEAFHTGCIPFYKHFQSAVKSCSQGGVRGGAATVFYPIWHLEIESLLVLK NNRGIEENRVRHLDYAVQINKLMYQRMLLGQKITLFSPSDVPKLYEFFFSDQKKFKEIYIKYEKNRNIRKKSINAIDLFC LIMRERASTGRIYIQHVDHCNSHSAFNSKLATIRQSNLCLEITLPTKPLNNIDDKNGEIALCTLSALNLGLINDLHDLKE LSTLSVRALDEILEYQNYPVVCAKKSAISRRSLGIGVINFAYYLAKNKVRYSDGSAKNLTHKTFEAIQYYLLKASCELAK EKGSCSLFNQTNYYLGKFPIDTYKKDIDSICNEPLHLNWNLLRKKIKKYGLRNSTLSALMPSETSSQISNATNGIEPPRG FISIKSSKDGMLRQVVPEYKKLKSEYELLWEIPNNIGYLELVAIMQKFVDQSISANTNYDPKRFLNEKIPMKQLIYDLLV AYKLGIKTLYYQNTRDGAEDNQNLNKSIENIKEDNCTSGSCTI
Sequences:
>Translated_763_residues MKNSLFVTKRNGKKEKINLDKIHKVLNWAAKGLENISVSQVELRSRIQFYNNISTVNIHETIIKAAADLISENTPDYQYM AARLAIFHLRKKAYGQFEPPNLYYHVKKMVQLGKYDEKLLQNYSFEEYVEMNSFVDHRRDMNFSYAAVKQLEAKYLLQNR VTGQIYESAQFLYILISACLFSKYEKKVRMNYIQRFYNAISTFKISLPTPIMSGVRTPTRQFSSCVLIECADNLNSINAT TSAIVKYVSQRAGIGINAGQIRALGSPIRNGEAFHTGCIPFYKHFQSAVKSCSQGGVRGGAATVFYPIWHLEIESLLVLK NNRGIEENRVRHLDYAVQINKLMYQRMLLGQKITLFSPSDVPKLYEFFFSDQKKFKEIYIKYEKNRNIRKKSINAIDLFC LIMRERASTGRIYIQHVDHCNSHSAFNSKLATIRQSNLCLEITLPTKPLNNIDDKNGEIALCTLSALNLGLINDLHDLKE LSTLSVRALDEILEYQNYPVVCAKKSAISRRSLGIGVINFAYYLAKNKVRYSDGSAKNLTHKTFEAIQYYLLKASCELAK EKGSCSLFNQTNYYLGKFPIDTYKKDIDSICNEPLHLNWNLLRKKIKKYGLRNSTLSALMPSETSSQISNATNGIEPPRG FISIKSSKDGMLRQVVPEYKKLKSEYELLWEIPNNIGYLELVAIMQKFVDQSISANTNYDPKRFLNEKIPMKQLIYDLLV AYKLGIKTLYYQNTRDGAEDNQNLNKSIENIKEDNCTSGSCTI >Mature_763_residues MKNSLFVTKRNGKKEKINLDKIHKVLNWAAKGLENISVSQVELRSRIQFYNNISTVNIHETIIKAAADLISENTPDYQYM AARLAIFHLRKKAYGQFEPPNLYYHVKKMVQLGKYDEKLLQNYSFEEYVEMNSFVDHRRDMNFSYAAVKQLEAKYLLQNR VTGQIYESAQFLYILISACLFSKYEKKVRMNYIQRFYNAISTFKISLPTPIMSGVRTPTRQFSSCVLIECADNLNSINAT TSAIVKYVSQRAGIGINAGQIRALGSPIRNGEAFHTGCIPFYKHFQSAVKSCSQGGVRGGAATVFYPIWHLEIESLLVLK NNRGIEENRVRHLDYAVQINKLMYQRMLLGQKITLFSPSDVPKLYEFFFSDQKKFKEIYIKYEKNRNIRKKSINAIDLFC LIMRERASTGRIYIQHVDHCNSHSAFNSKLATIRQSNLCLEITLPTKPLNNIDDKNGEIALCTLSALNLGLINDLHDLKE LSTLSVRALDEILEYQNYPVVCAKKSAISRRSLGIGVINFAYYLAKNKVRYSDGSAKNLTHKTFEAIQYYLLKASCELAK EKGSCSLFNQTNYYLGKFPIDTYKKDIDSICNEPLHLNWNLLRKKIKKYGLRNSTLSALMPSETSSQISNATNGIEPPRG FISIKSSKDGMLRQVVPEYKKLKSEYELLWEIPNNIGYLELVAIMQKFVDQSISANTNYDPKRFLNEKIPMKQLIYDLLV AYKLGIKTLYYQNTRDGAEDNQNLNKSIENIKEDNCTSGSCTI
Specific function: Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
COG id: COG0209
COG function: function code F; Ribonucleotide reductase, alpha subunit
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 ATP-cone domain
Homologues:
Organism=Homo sapiens, GI4506749, Length=791, Percent_Identity=27.9393173198483, Blast_Score=247, Evalue=4e-65, Organism=Escherichia coli, GI2367133, Length=763, Percent_Identity=73.394495412844, Blast_Score=1224, Evalue=0.0, Organism=Escherichia coli, GI1789030, Length=654, Percent_Identity=24.9235474006116, Blast_Score=162, Evalue=7e-41, Organism=Caenorhabditis elegans, GI17555242, Length=739, Percent_Identity=27.7401894451962, Blast_Score=241, Evalue=8e-64, Organism=Saccharomyces cerevisiae, GI6322123, Length=783, Percent_Identity=27.0753512132823, Blast_Score=245, Evalue=2e-65, Organism=Saccharomyces cerevisiae, GI6320914, Length=810, Percent_Identity=27.1604938271605, Blast_Score=244, Evalue=5e-65, Organism=Drosophila melanogaster, GI17352481, Length=786, Percent_Identity=27.2264631043257, Blast_Score=244, Evalue=2e-64,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): RIR1_BUCAP (Q8K9W3)
Other databases:
- EMBL: AE013218 - RefSeq: NP_660528.1 - ProteinModelPortal: Q8K9W3 - SMR: Q8K9W3 - EnsemblBacteria: EBBUCT00000000192 - GeneID: 1005370 - GenomeReviews: AE013218_GR - KEGG: bas:BUsg173 - GeneTree: EBGT00050000007695 - HOGENOM: HBG297012 - OMA: TTYAQGI - ProtClustDB: PRK09103 - BioCyc: BAPH198804:BUSG173-MONOMER - InterPro: IPR005144 - InterPro: IPR013346 - InterPro: IPR013509 - InterPro: IPR000788 - InterPro: IPR008926 - PANTHER: PTHR11573 - PRINTS: PR01183 - TIGRFAMs: TIGR02506
Pfam domain/function: PF03477 ATP-cone; PF02867 Ribonuc_red_lgC; PF00317 Ribonuc_red_lgN; SSF48168 Ribonucleo_red_N
EC number: =1.17.4.1
Molecular weight: Translated: 87472; Mature: 87472
Theoretical pI: Translated: 9.71; Mature: 9.71
Prosite motif: PS51161 ATP_CONE; PS00089 RIBORED_LARGE
Important sites: ACT_SITE 437-437 ACT_SITE 439-439 ACT_SITE 441-441 BINDING 9-9 BINDING 55-55 BINDING 91-91 BINDING 209-209 BINDING 253-253
Signals:
None
Transmembrane regions:
None
Cys/Met content:
2.0 %Cys (Translated Protein) 1.8 %Met (Translated Protein) 3.8 %Cys+Met (Translated Protein) 2.0 %Cys (Mature Protein) 1.8 %Met (Mature Protein) 3.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKNSLFVTKRNGKKEKINLDKIHKVLNWAAKGLENISVSQVELRSRIQFYNNISTVNIHE CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEHHHH TIIKAAADLISENTPDYQYMAARLAIFHLRKKAYGQFEPPNLYYHVKKMVQLGKYDEKLL HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHH QNYSFEEYVEMNSFVDHRRDMNFSYAAVKQLEAKYLLQNRVTGQIYESAQFLYILISACL HCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH FSKYEKKVRMNYIQRFYNAISTFKISLPTPIMSGVRTPTRQFSSCVLIECADNLNSINAT HHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHCCCCCHHHHCCEEEEEECCCCCCCCHH TSAIVKYVSQRAGIGINAGQIRALGSPIRNGEAFHTGCIPFYKHFQSAVKSCSQGGVRGG HHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCC AATVFYPIWHLEIESLLVLKNNRGIEENRVRHLDYAVQINKLMYQRMLLGQKITLFSPSD CEEEEEEEEHEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCC VPKLYEFFFSDQKKFKEIYIKYEKNRNIRKKSINAIDLFCLIMRERASTGRIYIQHVDHC HHHHHHHHHCCHHHHHHHEEEECCCCCHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCC NSHSAFNSKLATIRQSNLCLEITLPTKPLNNIDDKNGEIALCTLSALNLGLINDLHDLKE CCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHH LSTLSVRALDEILEYQNYPVVCAKKSAISRRSLGIGVINFAYYLAKNKVRYSDGSAKNLT HHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCCCCH HKTFEAIQYYLLKASCELAKEKGSCSLFNQTNYYLGKFPIDTYKKDIDSICNEPLHLNWN HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCHHHHHHHHHHHCCCCEECCHH LLRKKIKKYGLRNSTLSALMPSETSSQISNATNGIEPPRGFISIKSSKDGMLRQVVPEYK HHHHHHHHCCCCCCHHHHHCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHH KLKSEYELLWEIPNNIGYLELVAIMQKFVDQSISANTNYDPKRFLNEKIPMKQLIYDLLV HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHH AYKLGIKTLYYQNTRDGAEDNQNLNKSIENIKEDNCTSGSCTI HHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC >Mature Secondary Structure MKNSLFVTKRNGKKEKINLDKIHKVLNWAAKGLENISVSQVELRSRIQFYNNISTVNIHE CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEHHHH TIIKAAADLISENTPDYQYMAARLAIFHLRKKAYGQFEPPNLYYHVKKMVQLGKYDEKLL HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHH QNYSFEEYVEMNSFVDHRRDMNFSYAAVKQLEAKYLLQNRVTGQIYESAQFLYILISACL HCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH FSKYEKKVRMNYIQRFYNAISTFKISLPTPIMSGVRTPTRQFSSCVLIECADNLNSINAT HHHHHHHHHHHHHHHHHHHHHEEEEECCCHHHHCCCCCHHHHCCEEEEEECCCCCCCCHH TSAIVKYVSQRAGIGINAGQIRALGSPIRNGEAFHTGCIPFYKHFQSAVKSCSQGGVRGG HHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHCCCCCCC AATVFYPIWHLEIESLLVLKNNRGIEENRVRHLDYAVQINKLMYQRMLLGQKITLFSPSD CEEEEEEEEHEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCC VPKLYEFFFSDQKKFKEIYIKYEKNRNIRKKSINAIDLFCLIMRERASTGRIYIQHVDHC HHHHHHHHHCCHHHHHHHEEEECCCCCHHHHCCHHHHHHHHHHHHCCCCCEEEEEECCCC NSHSAFNSKLATIRQSNLCLEITLPTKPLNNIDDKNGEIALCTLSALNLGLINDLHDLKE CCCHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHH LSTLSVRALDEILEYQNYPVVCAKKSAISRRSLGIGVINFAYYLAKNKVRYSDGSAKNLT HHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHCCCHHHHHHHHHHCCCEEECCCCCCCCH HKTFEAIQYYLLKASCELAKEKGSCSLFNQTNYYLGKFPIDTYKKDIDSICNEPLHLNWN HHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCHHHHHHHHHHHCCCCEECCHH LLRKKIKKYGLRNSTLSALMPSETSSQISNATNGIEPPRGFISIKSSKDGMLRQVVPEYK HHHHHHHHCCCCCCHHHHHCCCCHHHHHHHCCCCCCCCCCEEEEECCCCCHHHHHHHHHH KLKSEYELLWEIPNNIGYLELVAIMQKFVDQSISANTNYDPKRFLNEKIPMKQLIYDLLV HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHHHHHHH AYKLGIKTLYYQNTRDGAEDNQNLNKSIENIKEDNCTSGSCTI HHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 12089438