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The map label for this gene is ispE [H]

Identifier: 213693331

GI number: 213693331

Start: 2814653

End: 2815603

Strand: Direct

Name: ispE [H]

Synonym: Blon_2485

Alternate gene names: 213693331

Gene position: 2814653-2815603 (Clockwise)

Preceding gene: 213693330

Following gene: 213693332

Centisome position: 99.36

GC content: 62.99

Gene sequence:

>951_bases
ATGAGTCCGGTAATTTCACATCCACGCCCAGCCGCTGCCCGACATCAGTTCGATGAGCTCTCCCCCATCACCATTACGGT
GGATTGCCCGGCTAAAACCAATCTCACCTTGGAAGTGGGGCCTGCTCACGACGAGTGGGGCGGACGCCACGAACTGGACA
CCATCTACTGTGCAATCGGTGTATACGACACCGTCACCGCAACCGCCAAGCAACCCGGAGCGGGATTCTCTCTGGAGCTC
GAAGGCGCTTATTTGGGCGACTTGGCCTCCTCACGCAGCGACATGCGCCGCAACCATGCGGTACTGGCCCTCTTCGCCAT
GGCCCAGGCGGCCGAACGCGAGCCGGATGTGGCGTTGACCATTACCAAGCGCATTCCCGTGGGTGCCGGACTAGGCGGCG
GTTCAGCCGACGCCGCGGCGACCATGCTGGCGGTCAATCGTCTCTGGGAGCTGAACTGGCCTATAGAGCGCCTGCGCACC
ATTGCCGCCACGTTGGGCGCGGACATGCCGTTCTGCCTGACCGGTGGCCTTGCATACGGCACCGGTTTCGGCGAACGCAT
CACGGATATCGCCCCCGGCAGCCGCGATGAGCTGGCGCTGATAGAACAGGGATTCAGCGGCGAAGTATTGGTCGGCGCGT
ACCAGTCGCAACTCAGCACTCCTGAGGTCTACCACACCTTTGACCTCGTGGGAGCCGCAGAAGGCGACCGCAATCATCTG
CAGGCTGCGGCAATCAGCCTGCATCCCCGCAGCGGGCAGGCCATCGACGCCGCCACGCAGGCGGGTGCCAGCCATGCATT
CGTCTCCGGATCCGGCCCCTCAGTGGTCGCTTTCGCCGCCGACGAGGCAGCGGCACAACGCATTATCGATGTGTGGCGCG
ATACGGCTGTGGTCGATCGCATTATTCGAGCCAAATCTCCCGCACACCCCAATATCGGCGTCAGACAGTGA

Upstream 100 bases:

>100_bases
CCGGCATCGATCCGACCCGTCGAGGAGAGACGCTCACCATCGCCGAATTCACCGCTCTGGCCAAGGCCATCGAATCGTGT
GGAGATGGAGATGAGGCACA

Downstream 100 bases:

>100_bases
CGCTAAGGTAGCAACCAGCCACCCGACCCATGAAAGAAGTCCACCGATGACGTATCAGGTTGATGAACGTGAAGCCCGCA
AGGCGTACGTGCGCCGCCGC

Product: 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase

Products: NA

Alternate protein names: CMK; 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase [H]

Number of amino acids: Translated: 316; Mature: 315

Protein sequence:

>316_residues
MSPVISHPRPAAARHQFDELSPITITVDCPAKTNLTLEVGPAHDEWGGRHELDTIYCAIGVYDTVTATAKQPGAGFSLEL
EGAYLGDLASSRSDMRRNHAVLALFAMAQAAEREPDVALTITKRIPVGAGLGGGSADAAATMLAVNRLWELNWPIERLRT
IAATLGADMPFCLTGGLAYGTGFGERITDIAPGSRDELALIEQGFSGEVLVGAYQSQLSTPEVYHTFDLVGAAEGDRNHL
QAAAISLHPRSGQAIDAATQAGASHAFVSGSGPSVVAFAADEAAAQRIIDVWRDTAVVDRIIRAKSPAHPNIGVRQ

Sequences:

>Translated_316_residues
MSPVISHPRPAAARHQFDELSPITITVDCPAKTNLTLEVGPAHDEWGGRHELDTIYCAIGVYDTVTATAKQPGAGFSLEL
EGAYLGDLASSRSDMRRNHAVLALFAMAQAAEREPDVALTITKRIPVGAGLGGGSADAAATMLAVNRLWELNWPIERLRT
IAATLGADMPFCLTGGLAYGTGFGERITDIAPGSRDELALIEQGFSGEVLVGAYQSQLSTPEVYHTFDLVGAAEGDRNHL
QAAAISLHPRSGQAIDAATQAGASHAFVSGSGPSVVAFAADEAAAQRIIDVWRDTAVVDRIIRAKSPAHPNIGVRQ
>Mature_315_residues
SPVISHPRPAAARHQFDELSPITITVDCPAKTNLTLEVGPAHDEWGGRHELDTIYCAIGVYDTVTATAKQPGAGFSLELE
GAYLGDLASSRSDMRRNHAVLALFAMAQAAEREPDVALTITKRIPVGAGLGGGSADAAATMLAVNRLWELNWPIERLRTI
AATLGADMPFCLTGGLAYGTGFGERITDIAPGSRDELALIEQGFSGEVLVGAYQSQLSTPEVYHTFDLVGAAEGDRNHLQ
AAAISLHPRSGQAIDAATQAGASHAFVSGSGPSVVAFAADEAAAQRIIDVWRDTAVVDRIIRAKSPAHPNIGVRQ

Specific function: Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol [H]

COG id: COG1947

COG function: function code I; 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GHMP kinase family. IspE subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006204
- InterPro:   IPR013750
- InterPro:   IPR004424
- InterPro:   IPR020568
- InterPro:   IPR014721 [H]

Pfam domain/function: PF08544 GHMP_kinases_C; PF00288 GHMP_kinases_N [H]

EC number: =2.7.1.148 [H]

Molecular weight: Translated: 33255; Mature: 33124

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPVISHPRPAAARHQFDELSPITITVDCPAKTNLTLEVGPAHDEWGGRHELDTIYCAIG
CCCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCEEEEEEE
VYDTVTATAKQPGAGFSLELEGAYLGDLASSRSDMRRNHAVLALFAMAQAAEREPDVALT
CHHHHEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
ITKRIPVGAGLGGGSADAAATMLAVNRLWELNWPIERLRTIAATLGADMPFCLTGGLAYG
EEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCC
TGFGERITDIAPGSRDELALIEQGFSGEVLVGAYQSQLSTPEVYHTFDLVGAAEGDRNHL
CCCCHHHHHCCCCCCCCCHHHHCCCCCCEEEEEHHHHCCCCHHEEEEEEEECCCCCCHHE
QAAAISLHPRSGQAIDAATQAGASHAFVSGSGPSVVAFAADEAAAQRIIDVWRDTAVVDR
EEEEEEECCCCCCEEHHHHHCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHH
IIRAKSPAHPNIGVRQ
HHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SPVISHPRPAAARHQFDELSPITITVDCPAKTNLTLEVGPAHDEWGGRHELDTIYCAIG
CCCCCCCCCHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCEEEEEEE
VYDTVTATAKQPGAGFSLELEGAYLGDLASSRSDMRRNHAVLALFAMAQAAEREPDVALT
CHHHHEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
ITKRIPVGAGLGGGSADAAATMLAVNRLWELNWPIERLRTIAATLGADMPFCLTGGLAYG
EEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCC
TGFGERITDIAPGSRDELALIEQGFSGEVLVGAYQSQLSTPEVYHTFDLVGAAEGDRNHL
CCCCHHHHHCCCCCCCCCHHHHCCCCCCEEEEEHHHHCCCCHHEEEEEEEECCCCCCHHE
QAAAISLHPRSGQAIDAATQAGASHAFVSGSGPSVVAFAADEAAAQRIIDVWRDTAVVDR
EEEEEEECCCCCCEEHHHHHCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHH
IIRAKSPAHPNIGVRQ
HHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA