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The map label for this gene is degA [H]

Identifier: 213693160

GI number: 213693160

Start: 2564248

End: 2565276

Strand: Direct

Name: degA [H]

Synonym: Blon_2310

Alternate gene names: 213693160

Gene position: 2564248-2565276 (Clockwise)

Preceding gene: 213693155

Following gene: 213693169

Centisome position: 90.52

GC content: 58.79

Gene sequence:

>1029_bases
ATGGCCAACGACAATCCCACGCATAAGCTCAAGGTCGGTGATCTGGCGAAGATCGCCGGTGTCTCCCCCTCGACCGTCTC
CAAGGTGATCAACGGCCGGCCCGGCATCTCCGACGAGATGCGACGTCAGGTCGAACAGGTGCTGCGCGAGCATGGTTACT
CGCGCCCGCTGGTGAGTACCAAGCTCTCCCCCACCATCGAACTCGTCGTCGAGTACATCGCGCACAACGGCACGATGGAA
CTCATCAAATATGCCTCGCACTGGGCGCAGCAGGCGGGCCTCGCCATCACGGTCACCCAGACCAACCATGGCGATGCCAC
GGAAGACTGTTTCCGCGGCATCATCGATAGGAATCCCCAAGGCGTGATTATGCAGCAGATGGGCGGTCTGACCACTCAAG
CGAAGTCTTTGTTGAAATCACGCAGTATTCCCGTGGTCATCATCGACCCAATCGATACCGTCGATTCGGATGTGATGAGC
GTGTCCATCGATAACTGGACCGCAGGATACCAGGCCGGCAAACACCTGCTGTCGCTCGGCCATCGACGCATCGCCGTCAT
CCGGGGGCCGGCGAACCTACAGACCAGCATCGCGCGCTATAGCGGATTCACCGTCGCTCTGCAACAGGCCGGGGTGGATC
TGCCGGAGTCCTATATCGAACAGGGCGACTACTTTCCCGCCGAAACAAGCTATGAAGCAGCCTGCCGGCTGCTGGAACTC
CCCGACCGACCCACCGCGATTTTCTGCTGCAACGACTTGTCGGCGGTAAGCACGTATCGCGCGGCACGTGAACATAAGAT
TCCGTTACCCAAACAGTTGTCCGTAATGGGGTTTGACGACATTTTCCCCGCTGATCAGCTCATGCCTTCCCTGACCAGCG
TGCACCAGCCGTTCAGCGAAATCGCACAACGTGCCGTGCAGATGATCATCGACAACCGCAATGACAATCCGGGCGATATG
CACGTCATCCTTCCCACCAGCGTCGTCATCCGGGAAAGTACCGTACCGCCTCAGTCATCAGCCCGATAA

Upstream 100 bases:

>100_bases
AAATTTTTCTCCCAGAACACGCGAAGTAAGGAAAACTACGAAAAAATGCGGCGTTATGGGCCATAATGGTGAACAGAGGC
AATGGCAGAGAGGAGCGGTG

Downstream 100 bases:

>100_bases
TCGGCCAGATTCAAGCTGGCCGCCACCCGATTGGACGCGAACGCGCCGATGGAGACCAGCGCATAGCACAGCACAAGCCC
GCCGAAGAAGCTGGCCAGCG

Product: periplasmic binding protein/LacI transcriptional regulator

Products: NA

Alternate protein names: Degradation activator [H]

Number of amino acids: Translated: 342; Mature: 341

Protein sequence:

>342_residues
MANDNPTHKLKVGDLAKIAGVSPSTVSKVINGRPGISDEMRRQVEQVLREHGYSRPLVSTKLSPTIELVVEYIAHNGTME
LIKYASHWAQQAGLAITVTQTNHGDATEDCFRGIIDRNPQGVIMQQMGGLTTQAKSLLKSRSIPVVIIDPIDTVDSDVMS
VSIDNWTAGYQAGKHLLSLGHRRIAVIRGPANLQTSIARYSGFTVALQQAGVDLPESYIEQGDYFPAETSYEAACRLLEL
PDRPTAIFCCNDLSAVSTYRAAREHKIPLPKQLSVMGFDDIFPADQLMPSLTSVHQPFSEIAQRAVQMIIDNRNDNPGDM
HVILPTSVVIRESTVPPQSSAR

Sequences:

>Translated_342_residues
MANDNPTHKLKVGDLAKIAGVSPSTVSKVINGRPGISDEMRRQVEQVLREHGYSRPLVSTKLSPTIELVVEYIAHNGTME
LIKYASHWAQQAGLAITVTQTNHGDATEDCFRGIIDRNPQGVIMQQMGGLTTQAKSLLKSRSIPVVIIDPIDTVDSDVMS
VSIDNWTAGYQAGKHLLSLGHRRIAVIRGPANLQTSIARYSGFTVALQQAGVDLPESYIEQGDYFPAETSYEAACRLLEL
PDRPTAIFCCNDLSAVSTYRAAREHKIPLPKQLSVMGFDDIFPADQLMPSLTSVHQPFSEIAQRAVQMIIDNRNDNPGDM
HVILPTSVVIRESTVPPQSSAR
>Mature_341_residues
ANDNPTHKLKVGDLAKIAGVSPSTVSKVINGRPGISDEMRRQVEQVLREHGYSRPLVSTKLSPTIELVVEYIAHNGTMEL
IKYASHWAQQAGLAITVTQTNHGDATEDCFRGIIDRNPQGVIMQQMGGLTTQAKSLLKSRSIPVVIIDPIDTVDSDVMSV
SIDNWTAGYQAGKHLLSLGHRRIAVIRGPANLQTSIARYSGFTVALQQAGVDLPESYIEQGDYFPAETSYEAACRLLELP
DRPTAIFCCNDLSAVSTYRAAREHKIPLPKQLSVMGFDDIFPADQLMPSLTSVHQPFSEIAQRAVQMIIDNRNDNPGDMH
VILPTSVVIRESTVPPQSSAR

Specific function: Involved in the control of degradation of B.subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease [H]

COG id: COG1609

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=337, Percent_Identity=30.5637982195846, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1790369, Length=327, Percent_Identity=29.6636085626911, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1790194, Length=311, Percent_Identity=29.903536977492, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1789068, Length=304, Percent_Identity=29.6052631578947, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1787580, Length=335, Percent_Identity=26.5671641791045, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1788474, Length=348, Percent_Identity=28.735632183908, Blast_Score=101, Evalue=8e-23,
Organism=Escherichia coli, GI1786540, Length=338, Percent_Identity=23.6686390532544, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1789202, Length=305, Percent_Identity=25.5737704918033, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787906, Length=289, Percent_Identity=24.2214532871972, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37452; Mature: 37321

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANDNPTHKLKVGDLAKIAGVSPSTVSKVINGRPGISDEMRRQVEQVLREHGYSRPLVST
CCCCCCCCEEECCCHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
KLSPTIELVVEYIAHNGTMELIKYASHWAQQAGLAITVTQTNHGDATEDCFRGIIDRNPQ
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCCC
GVIMQQMGGLTTQAKSLLKSRSIPVVIIDPIDTVDSDVMSVSIDNWTAGYQAGKHLLSLG
CHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHCC
HRRIAVIRGPANLQTSIARYSGFTVALQQAGVDLPESYIEQGDYFPAETSYEAACRLLEL
CCEEEEEECCCCHHHHHHHHCCCEEEHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHHHCC
PDRPTAIFCCNDLSAVSTYRAAREHKIPLPKQLSVMGFDDIFPADQLMPSLTSVHQPFSE
CCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCEEECCCHHCCCHHHHHHHHHHHHHHHHH
IAQRAVQMIIDNRNDNPGDMHVILPTSVVIRESTVPPQSSAR
HHHHHHHHHHCCCCCCCCCEEEEECCEEEEECCCCCCCCCCC
>Mature Secondary Structure 
ANDNPTHKLKVGDLAKIAGVSPSTVSKVINGRPGISDEMRRQVEQVLREHGYSRPLVST
CCCCCCCEEECCCHHHHCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
KLSPTIELVVEYIAHNGTMELIKYASHWAQQAGLAITVTQTNHGDATEDCFRGIIDRNPQ
CCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHHHCCCCC
GVIMQQMGGLTTQAKSLLKSRSIPVVIIDPIDTVDSDVMSVSIDNWTAGYQAGKHLLSLG
CHHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCCCCEEEEECCCHHHHHHHHHHHHCC
HRRIAVIRGPANLQTSIARYSGFTVALQQAGVDLPESYIEQGDYFPAETSYEAACRLLEL
CCEEEEEECCCCHHHHHHHHCCCEEEHHHCCCCCCHHHHHCCCCCCCCCCHHHHHHHHCC
PDRPTAIFCCNDLSAVSTYRAAREHKIPLPKQLSVMGFDDIFPADQLMPSLTSVHQPFSE
CCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCEEECCCHHCCCHHHHHHHHHHHHHHHHH
IAQRAVQMIIDNRNDNPGDMHVILPTSVVIRESTVPPQSSAR
HHHHHHHHHHCCCCCCCCCEEEEECCEEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407808; 9353932; 9384377 [H]