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The map label for this gene is nreC [H]

Identifier: 213693023

GI number: 213693023

Start: 2403454

End: 2404149

Strand: Direct

Name: nreC [H]

Synonym: Blon_2170

Alternate gene names: 213693023

Gene position: 2403454-2404149 (Clockwise)

Preceding gene: 213693022

Following gene: 213693032

Centisome position: 84.85

GC content: 61.35

Gene sequence:

>696_bases
ATGAGCGAGAACGAGACAGCCAAGATTCGTGTGGCCGTGGTCGATGACCATGAGATGTTCCGTGCGGGCGTAATCGCCAC
ATTGCGCGATTCCTTCGATATCGTCGGCCAAGCGGCGGACGTGCCCGGTTCGGTGGCGATGATCGCACAGACCAAGCCGC
AAGTGGTGTTGCTGGATGTGCATGTGCCCGGCGGTGAAGGTGGCGGCGGTGCCGAGATCCTCGCCAAATCGCGCTCCTAC
TCCCCTACTACCGTGTTTCTGGCGTTGTCGGTTTCGGATGCGCCGCAGGATGTGGGGGCGGTGATTCGTGCCGGCGCCCA
GGGCTATGTGACCAAGACGATTACCGGCGCTGATTTGATTTCATCCATCAAGCAGGTGCATGAGGGCTATGCCGTGTTCT
CGCCAAAACTGGCCGGTTTTGTGCTTTCGGCCTTCCAGGGTGTGCCGGCGGCGGGGTCTGATGGCGGCGCTGATGGTGCG
GCACGGGCTCATGATGAGGAGCTGGACCGGCTGTCCGCCCGCGAGCAGGAGGTCATGCGGCTGATCGCGCGTGGTTACAC
GTATAAAGAGGTGGCGGCCGAACTGTTCATTTCGATCAAGACGGTCGAAACGCACGTGAGCTCGGTGCTGCGAAAGCTTC
AGCTTTCGAATCGCACCGAGCTCACCCGCTGGGCCGCCGATAGGCGCATTGTGTGA

Upstream 100 bases:

>100_bases
GGCGCGGCGGTACAGTGGAGATAGTGTCCAGAGCCGGCTGGGGCACCGAGGTCAGAATGCATATGCCGATCGCGCTGAAA
GCGGCGCAGGGAGAACATCG

Downstream 100 bases:

>100_bases
TAAACGACAGATGAGCTCCCTCATCAGAGGGAGCTCATCTGCTCATATCACTCCGCGTCGCGGAAACCGTTGGGGTTCTT
GGTCTGCCAGTTGAGGGAGG

Product: two component transcriptional regulator, LuxR family

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 231; Mature: 230

Protein sequence:

>231_residues
MSENETAKIRVAVVDDHEMFRAGVIATLRDSFDIVGQAADVPGSVAMIAQTKPQVVLLDVHVPGGEGGGGAEILAKSRSY
SPTTVFLALSVSDAPQDVGAVIRAGAQGYVTKTITGADLISSIKQVHEGYAVFSPKLAGFVLSAFQGVPAAGSDGGADGA
ARAHDEELDRLSAREQEVMRLIARGYTYKEVAAELFISIKTVETHVSSVLRKLQLSNRTELTRWAADRRIV

Sequences:

>Translated_231_residues
MSENETAKIRVAVVDDHEMFRAGVIATLRDSFDIVGQAADVPGSVAMIAQTKPQVVLLDVHVPGGEGGGGAEILAKSRSY
SPTTVFLALSVSDAPQDVGAVIRAGAQGYVTKTITGADLISSIKQVHEGYAVFSPKLAGFVLSAFQGVPAAGSDGGADGA
ARAHDEELDRLSAREQEVMRLIARGYTYKEVAAELFISIKTVETHVSSVLRKLQLSNRTELTRWAADRRIV
>Mature_230_residues
SENETAKIRVAVVDDHEMFRAGVIATLRDSFDIVGQAADVPGSVAMIAQTKPQVVLLDVHVPGGEGGGGAEILAKSRSYS
PTTVFLALSVSDAPQDVGAVIRAGAQGYVTKTITGADLISSIKQVHEGYAVFSPKLAGFVLSAFQGVPAAGSDGGADGAA
RAHDEELDRLSAREQEVMRLIARGYTYKEVAAELFISIKTVETHVSSVLRKLQLSNRTELTRWAADRRIV

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788521, Length=220, Percent_Identity=29.5454545454545, Blast_Score=84, Evalue=5e-18,
Organism=Escherichia coli, GI1787473, Length=233, Percent_Identity=30.4721030042918, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1788712, Length=219, Percent_Identity=27.8538812785388, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI1790102, Length=221, Percent_Identity=28.9592760180996, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788546, Length=221, Percent_Identity=24.4343891402715, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1788222, Length=221, Percent_Identity=28.0542986425339, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786747, Length=218, Percent_Identity=24.7706422018349, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24493; Mature: 24362

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENETAKIRVAVVDDHEMFRAGVIATLRDSFDIVGQAADVPGSVAMIAQTKPQVVLLDV
CCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEE
HVPGGEGGGGAEILAKSRSYSPTTVFLALSVSDAPQDVGAVIRAGAQGYVTKTITGADLI
ECCCCCCCCCHHHEECCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCEEEEECHHHHH
SSIKQVHEGYAVFSPKLAGFVLSAFQGVPAAGSDGGADGAARAHDEELDRLSAREQEVMR
HHHHHHHCCCEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LIARGYTYKEVAAELFISIKTVETHVSSVLRKLQLSNRTELTRWAADRRIV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC
>Mature Secondary Structure 
SENETAKIRVAVVDDHEMFRAGVIATLRDSFDIVGQAADVPGSVAMIAQTKPQVVLLDV
CCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEE
HVPGGEGGGGAEILAKSRSYSPTTVFLALSVSDAPQDVGAVIRAGAQGYVTKTITGADLI
ECCCCCCCCCHHHEECCCCCCCEEEEEEEECCCCCHHHHHHHHCCCCCCEEEEECHHHHH
SSIKQVHEGYAVFSPKLAGFVLSAFQGVPAAGSDGGADGAARAHDEELDRLSAREQEVMR
HHHHHHHCCCEEECHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LIARGYTYKEVAAELFISIKTVETHVSSVLRKLQLSNRTELTRWAADRRIV
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12426351 [H]