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The map label for this gene is nudC [H]

Identifier: 213692930

GI number: 213692930

Start: 2290920

End: 2292212

Strand: Reverse

Name: nudC [H]

Synonym: Blon_2074

Alternate gene names: 213692930

Gene position: 2292212-2290920 (Counterclockwise)

Preceding gene: 213692931

Following gene: 213692929

Centisome position: 80.92

GC content: 66.59

Gene sequence:

>1293_bases
ATGACCGCTGACATTCATTTCTCACCTCTGGCACTGACCCATGCGCTGCCGTTCCTGCCGCTCGCGCAAGGTGACATCGA
CTATCAGGTGGACCGGCGCGGTGAACCCGGTCTGATCGACGAGCTGTTGGCCGAGCCGACCACCAAAGTCGTGCTTACGC
GCGGCGGACTTGTCGCCGTACCGCGCGGCCAAGGCGAGCTCGTGGACTATGAGAACGTGAAAATGCGGCTCGCCACGTTG
CCGGGCGCCTATGTGTCCGCCGAACTGGCACGCTACCCCGAAGCGGTCGCCATGTTCCTCGGCTCCTATGTCGGGGCGCG
CGGCGAATCCGTGGTCGCCGTGGATATCACGCGCGTGCCGGAAGCCGGTGTTCCCGGTGTTGACGGGATTGCTGATGTTT
CCGGTGCTGCCGGCGGCGTGCTCGGCACCCAGGATTCCGGCACCGTGGACGGCGCGCTGGGCAAGAACGGCATCAGCGGA
GGTGCTGCCGCCGGAATACGGCAGCCGGGAAATACCAAGGGCAATGGCGGCGTAGCCGCAGCCAAAATCGCCGGGCCGCT
CGGTGTACCGGATTCGGCCGGGCAAGGTGCGGACGATGCCTTCGATGATTCGGTCGGCGCGCCCGTACAACCCTTGGTCC
CGAAGCCCACGCTGTTGCAACAGGCCGTGACCCGGTTCGACTGGGTGGACCTGCGCGGATTCGCCCCTCACGCCAACGCG
CGCGAGGCTGGGCAAGCCACCAGTGCCATCACCTTAAGCATCTGGCACAGCCGCCAGCGGTTCTGCCCCACCTGTGGCGC
GGCGGTCCGGCCGGCGCTCGCCGGATGGGCGCAGCGATGCACCAACGAGGCGGACGGCAACCGTGTGCTGTTCCCGCGCG
TGGAGCCGGCGGTCATCACCGCCATCGTGGACGGGCACGACCGTCTGCTGCTGCAACACAACGCGGCATGGAATGATTCG
AGGCTGTATTCGGTGTCCGCCGGATTTGTGGAGGCGGGGGAGAACCTTGAACACGCCTGCCGCCGCGAGGCCATGGAAGA
GACCGGCATCAAGCTCGGCGAGGTGCGGTACCTGGGCTCGCAGCCGTGGCCGTTCCCGGCTTCGCTGATGATGGCGTTCA
AAGCACATGCAATCACCACCGACGTGCATGTGGACGGCGAGGAGACCATGACCGCGCGATGGGTCACACGCGACGAATAC
ACGGCCGAGCTCATCGCCGGCCGTATGGCGGCGCCGGGCCGCGCCACCATCGCCCGCTACATGATTGAGGAATGGCTCGG
TCGCGAGCTGTGA

Upstream 100 bases:

>100_bases
CCATTTCAGCGCCGTCGAACATCCGGATACCGTGGCGCGGGCGCTGCTCTCGCTTGTCAGGCGCGTGCAGAGCGCGCAGA
AGAACGCATAGGAGACCTCG

Downstream 100 bases:

>100_bases
CGGACCGCGAAGATAGGTTAGGCTTATGACTATGAGTGATGACAACGAAAACGAACAGCCGCTGAACCTCGACATTCCCG
ACCATCTCGAATACTCCGAG

Product: NUDIX hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 430; Mature: 429

Protein sequence:

>430_residues
MTADIHFSPLALTHALPFLPLAQGDIDYQVDRRGEPGLIDELLAEPTTKVVLTRGGLVAVPRGQGELVDYENVKMRLATL
PGAYVSAELARYPEAVAMFLGSYVGARGESVVAVDITRVPEAGVPGVDGIADVSGAAGGVLGTQDSGTVDGALGKNGISG
GAAAGIRQPGNTKGNGGVAAAKIAGPLGVPDSAGQGADDAFDDSVGAPVQPLVPKPTLLQQAVTRFDWVDLRGFAPHANA
REAGQATSAITLSIWHSRQRFCPTCGAAVRPALAGWAQRCTNEADGNRVLFPRVEPAVITAIVDGHDRLLLQHNAAWNDS
RLYSVSAGFVEAGENLEHACRREAMEETGIKLGEVRYLGSQPWPFPASLMMAFKAHAITTDVHVDGEETMTARWVTRDEY
TAELIAGRMAAPGRATIARYMIEEWLGREL

Sequences:

>Translated_430_residues
MTADIHFSPLALTHALPFLPLAQGDIDYQVDRRGEPGLIDELLAEPTTKVVLTRGGLVAVPRGQGELVDYENVKMRLATL
PGAYVSAELARYPEAVAMFLGSYVGARGESVVAVDITRVPEAGVPGVDGIADVSGAAGGVLGTQDSGTVDGALGKNGISG
GAAAGIRQPGNTKGNGGVAAAKIAGPLGVPDSAGQGADDAFDDSVGAPVQPLVPKPTLLQQAVTRFDWVDLRGFAPHANA
REAGQATSAITLSIWHSRQRFCPTCGAAVRPALAGWAQRCTNEADGNRVLFPRVEPAVITAIVDGHDRLLLQHNAAWNDS
RLYSVSAGFVEAGENLEHACRREAMEETGIKLGEVRYLGSQPWPFPASLMMAFKAHAITTDVHVDGEETMTARWVTRDEY
TAELIAGRMAAPGRATIARYMIEEWLGREL
>Mature_429_residues
TADIHFSPLALTHALPFLPLAQGDIDYQVDRRGEPGLIDELLAEPTTKVVLTRGGLVAVPRGQGELVDYENVKMRLATLP
GAYVSAELARYPEAVAMFLGSYVGARGESVVAVDITRVPEAGVPGVDGIADVSGAAGGVLGTQDSGTVDGALGKNGISGG
AAAGIRQPGNTKGNGGVAAAKIAGPLGVPDSAGQGADDAFDDSVGAPVQPLVPKPTLLQQAVTRFDWVDLRGFAPHANAR
EAGQATSAITLSIWHSRQRFCPTCGAAVRPALAGWAQRCTNEADGNRVLFPRVEPAVITAIVDGHDRLLLQHNAAWNDSR
LYSVSAGFVEAGENLEHACRREAMEETGIKLGEVRYLGSQPWPFPASLMMAFKAHAITTDVHVDGEETMTARWVTRDEYT
AELIAGRMAAPGRATIARYMIEEWLGREL

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI13899267, Length=197, Percent_Identity=38.5786802030457, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI50593112, Length=219, Percent_Identity=31.0502283105023, Blast_Score=102, Evalue=7e-22,
Organism=Escherichia coli, GI48994995, Length=179, Percent_Identity=36.8715083798883, Blast_Score=115, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI212645999, Length=176, Percent_Identity=33.5227272727273, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71986510, Length=176, Percent_Identity=33.5227272727273, Blast_Score=83, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321371, Length=198, Percent_Identity=32.8282828282828, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376 [H]

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase [H]

EC number: =3.6.1.22 [H]

Molecular weight: Translated: 45362; Mature: 45231

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTADIHFSPLALTHALPFLPLAQGDIDYQVDRRGEPGLIDELLAEPTTKVVLTRGGLVAV
CCCCCCCCHHHHHHHCCCCEECCCCCCEEECCCCCCCHHHHHHCCCCCEEEEECCCEEEE
PRGQGELVDYENVKMRLATLPGAYVSAELARYPEAVAMFLGSYVGARGESVVAVDITRVP
ECCCCCEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECC
EAGVPGVDGIADVSGAAGGVLGTQDSGTVDGALGKNGISGGAAAGIRQPGNTKGNGGVAA
CCCCCCCCCHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
AKIAGPLGVPDSAGQGADDAFDDSVGAPVQPLVPKPTLLQQAVTRFDWVDLRGFAPHANA
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCC
REAGQATSAITLSIWHSRQRFCPTCGAAVRPALAGWAQRCTNEADGNRVLFPRVEPAVIT
HHHCCCCCEEEEEEECCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEE
AIVDGHDRLLLQHNAAWNDSRLYSVSAGFVEAGENLEHACRREAMEETGIKLGEVRYLGS
EEECCCCEEEEEECCCCCCCEEEEEECCHHHCCCCHHHHHHHHHHHHHCCEEEEEEEECC
QPWPFPASLMMAFKAHAITTDVHVDGEETMTARWVTRDEYTAELIAGRMAAPGRATIARY
CCCCCHHHHHHHHHHHEEEEEEEECCCCCEEEEEEECCHHHHHHHHHCCCCCCHHHHHHH
MIEEWLGREL
HHHHHHCCCC
>Mature Secondary Structure 
TADIHFSPLALTHALPFLPLAQGDIDYQVDRRGEPGLIDELLAEPTTKVVLTRGGLVAV
CCCCCCCHHHHHHHCCCCEECCCCCCEEECCCCCCCHHHHHHCCCCCEEEEECCCEEEE
PRGQGELVDYENVKMRLATLPGAYVSAELARYPEAVAMFLGSYVGARGESVVAVDITRVP
ECCCCCEECCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEEECC
EAGVPGVDGIADVSGAAGGVLGTQDSGTVDGALGKNGISGGAAAGIRQPGNTKGNGGVAA
CCCCCCCCCHHHCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
AKIAGPLGVPDSAGQGADDAFDDSVGAPVQPLVPKPTLLQQAVTRFDWVDLRGFAPHANA
EEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEECCCCCCCCCC
REAGQATSAITLSIWHSRQRFCPTCGAAVRPALAGWAQRCTNEADGNRVLFPRVEPAVIT
HHHCCCCCEEEEEEECCCHHCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECCCCCEEEE
AIVDGHDRLLLQHNAAWNDSRLYSVSAGFVEAGENLEHACRREAMEETGIKLGEVRYLGS
EEECCCCEEEEEECCCCCCCEEEEEECCHHHCCCCHHHHHHHHHHHHHCCEEEEEEEECC
QPWPFPASLMMAFKAHAITTDVHVDGEETMTARWVTRDEYTAELIAGRMAAPGRATIARY
CCCCCHHHHHHHHHHHEEEEEEEECCCCCEEEEEEECCHHHHHHHHHCCCCCCHHHHHHH
MIEEWLGREL
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]