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The map label for this gene is namA [H]

Identifier: 213692922

GI number: 213692922

Start: 2279248

End: 2280363

Strand: Reverse

Name: namA [H]

Synonym: Blon_2066

Alternate gene names: 213692922

Gene position: 2280363-2279248 (Counterclockwise)

Preceding gene: 213692923

Following gene: 213692920

Centisome position: 80.5

GC content: 62.72

Gene sequence:

>1116_bases
GTGGGCAAGGCAGATAAGAAAGCCAGCAAGGACCGTCCTGGGCTGTTTGCGCCAATGACGCTGCGCGAGGTGACCGTGCG
TAATCGTATTTGGTTGCCTCCGATGTGCACGTATTCGTCGTTCGCCCGCGACGGTAGGCCCACGCCGTTCCACTACCAGC
ATTACGTGTCTCGCGCATTCGGCGGATTCGGCATGGTGATCGTCGAATCCACCGCCGTGGCTCCTGAGGGGCGTATCACG
CCGTGCGATCTGGGCCTGTGGGAAGACGGGCAGATTGATGCTTGGCGCTGGATCGTGGACGGTATTCGCGAGGCGGGTGC
GGTGCCTGCCATCCAACTCAACCATGCGGGGCGTAAGGCTTCGACTGGTTGTTTTGCCGTTGGCTACGACGGTCAGAGTG
TGCCGGAGGAGGCGGGCGGCTGGCCCACCATGGCACCGTCTGAAATCGCATTCGGCGGGCTGCGTACGCCGCGCGCGCTG
TCCGTGGATGAGATTCATGGTCTGGTCGGCGCGTTCGCCGCGGCGGCGGGCCGGGCGTCGGCCGCCGGCTTCCAAGCGAT
TCAAATTCATGCCGCGCATGGCTATCTGATTTCTCAGTTCCTTGACCCGCTGAGCAATGAGCGTGATGACGAATATGGTG
GCGATTTGACCGGTCGCTCTCGATTCCTGGTCGAGGTCGTGGATGCCGTGCGTGGGGCCGTCCCTGAGGGCGTGCCGGTT
CTGGTGCGCATTTCGGCCACGGATTGGGCCGCTGGCGGTTGGGATTTGGACCAGAGCATCGCACTATCCAAGGTGCTGAA
GGAGCATGGCGTCGATGTGATGGACGTGTCCACTGGCGGCATCATGTCGGGAGTGTCGATTCCGGTCAAGCCGAACTATC
AGGTGCCGTTCGCCGAGCAGGTCAAGTCCAAGGCCGATATTCCGGTGACCGCGGTGGGTCTTATCACCAAGCCGAAGCAG
GCGGCCAAGATTCTGGCCCATGGCGAAGCCGATGCCGTGGAAATTGGCCGCGCCGCATTGCGCGATCCGTACTGGCCGTT
GCGTGCGGCCAACAAGCTGGGCATACCGTCCACAGAGGTCCCCTACGCCCCGCAATACGTGGCCGGTGCGTACTAA

Upstream 100 bases:

>100_bases
AAAATCCGACGCACGGTCCAAGAAGCGGGCCGGCACGGGCAAGACGAGCGAATCGTTCGATGATTATGAGGATTATGAGG
ATTATGAGGGAAGGGAAGCT

Downstream 100 bases:

>100_bases
ATCCTCATGGGGCGGTAACTTTCCCATGGGGCGGTAAAACCCTCATGGGGCGGTAACCCAAAACGGCGGTATTCTGCGGA
ATGTGAAATTTGGCTAACCG

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 371; Mature: 370

Protein sequence:

>371_residues
MGKADKKASKDRPGLFAPMTLREVTVRNRIWLPPMCTYSSFARDGRPTPFHYQHYVSRAFGGFGMVIVESTAVAPEGRIT
PCDLGLWEDGQIDAWRWIVDGIREAGAVPAIQLNHAGRKASTGCFAVGYDGQSVPEEAGGWPTMAPSEIAFGGLRTPRAL
SVDEIHGLVGAFAAAAGRASAAGFQAIQIHAAHGYLISQFLDPLSNERDDEYGGDLTGRSRFLVEVVDAVRGAVPEGVPV
LVRISATDWAAGGWDLDQSIALSKVLKEHGVDVMDVSTGGIMSGVSIPVKPNYQVPFAEQVKSKADIPVTAVGLITKPKQ
AAKILAHGEADAVEIGRAALRDPYWPLRAANKLGIPSTEVPYAPQYVAGAY

Sequences:

>Translated_371_residues
MGKADKKASKDRPGLFAPMTLREVTVRNRIWLPPMCTYSSFARDGRPTPFHYQHYVSRAFGGFGMVIVESTAVAPEGRIT
PCDLGLWEDGQIDAWRWIVDGIREAGAVPAIQLNHAGRKASTGCFAVGYDGQSVPEEAGGWPTMAPSEIAFGGLRTPRAL
SVDEIHGLVGAFAAAAGRASAAGFQAIQIHAAHGYLISQFLDPLSNERDDEYGGDLTGRSRFLVEVVDAVRGAVPEGVPV
LVRISATDWAAGGWDLDQSIALSKVLKEHGVDVMDVSTGGIMSGVSIPVKPNYQVPFAEQVKSKADIPVTAVGLITKPKQ
AAKILAHGEADAVEIGRAALRDPYWPLRAANKLGIPSTEVPYAPQYVAGAY
>Mature_370_residues
GKADKKASKDRPGLFAPMTLREVTVRNRIWLPPMCTYSSFARDGRPTPFHYQHYVSRAFGGFGMVIVESTAVAPEGRITP
CDLGLWEDGQIDAWRWIVDGIREAGAVPAIQLNHAGRKASTGCFAVGYDGQSVPEEAGGWPTMAPSEIAFGGLRTPRALS
VDEIHGLVGAFAAAAGRASAAGFQAIQIHAAHGYLISQFLDPLSNERDDEYGGDLTGRSRFLVEVVDAVRGAVPEGVPVL
VRISATDWAAGGWDLDQSIALSKVLKEHGVDVMDVSTGGIMSGVSIPVKPNYQVPFAEQVKSKADIPVTAVGLITKPKQA
AKILAHGEADAVEIGRAALRDPYWPLRAANKLGIPSTEVPYAPQYVAGAY

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=348, Percent_Identity=29.8850574712644, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789463, Length=338, Percent_Identity=28.9940828402367, Blast_Score=119, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17559804, Length=346, Percent_Identity=26.3005780346821, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17540738, Length=348, Percent_Identity=25.5747126436782, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17565138, Length=325, Percent_Identity=23.6923076923077, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17564188, Length=274, Percent_Identity=27.007299270073, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17559802, Length=329, Percent_Identity=24.3161094224924, Blast_Score=108, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI72001454, Length=320, Percent_Identity=26.25, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17566914, Length=320, Percent_Identity=27.5, Blast_Score=100, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6321973, Length=228, Percent_Identity=32.0175438596491, Blast_Score=100, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6325086, Length=221, Percent_Identity=29.8642533936652, Blast_Score=95, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39545; Mature: 39414

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKADKKASKDRPGLFAPMTLREVTVRNRIWLPPMCTYSSFARDGRPTPFHYQHYVSRAF
CCCCCCCCCCCCCCEECCHHHHHHHHHCEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHC
GGFGMVIVESTAVAPEGRITPCDLGLWEDGQIDAWRWIVDGIREAGAVPAIQLNHAGRKA
CCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCC
STGCFAVGYDGQSVPEEAGGWPTMAPSEIAFGGLRTPRALSVDEIHGLVGAFAAAAGRAS
CCCEEEECCCCCCCCHHHCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
AAGFQAIQIHAAHGYLISQFLDPLSNERDDEYGGDLTGRSRFLVEVVDAVRGAVPEGVPV
CCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEE
LVRISATDWAAGGWDLDQSIALSKVLKEHGVDVMDVSTGGIMSGVSIPVKPNYQVPFAEQ
EEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCEECCCEECCCCCCCCCHHHH
VKSKADIPVTAVGLITKPKQAAKILAHGEADAVEIGRAALRDPYWPLRAANKLGIPSTEV
HHCCCCCCEEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHCCCCCCCCCCCC
PYAPQYVAGAY
CCCCCHHCCCC
>Mature Secondary Structure 
GKADKKASKDRPGLFAPMTLREVTVRNRIWLPPMCTYSSFARDGRPTPFHYQHYVSRAF
CCCCCCCCCCCCCEECCHHHHHHHHHCEECCCCCCCHHHHHHCCCCCCHHHHHHHHHHC
GGFGMVIVESTAVAPEGRITPCDLGLWEDGQIDAWRWIVDGIREAGAVPAIQLNHAGRKA
CCCEEEEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCC
STGCFAVGYDGQSVPEEAGGWPTMAPSEIAFGGLRTPRALSVDEIHGLVGAFAAAAGRAS
CCCEEEECCCCCCCCHHHCCCCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCC
AAGFQAIQIHAAHGYLISQFLDPLSNERDDEYGGDLTGRSRFLVEVVDAVRGAVPEGVPV
CCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEE
LVRISATDWAAGGWDLDQSIALSKVLKEHGVDVMDVSTGGIMSGVSIPVKPNYQVPFAEQ
EEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCEECCCEECCCCCCCCCHHHH
VKSKADIPVTAVGLITKPKQAAKILAHGEADAVEIGRAALRDPYWPLRAANKLGIPSTEV
HHCCCCCCEEEEEEECCCHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHCCCCCCCCCCCC
PYAPQYVAGAY
CCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]