Click here to switch to the map view.

The map label for this gene is dapA [H]

Identifier: 213692893

GI number: 213692893

Start: 2226639

End: 2227544

Strand: Reverse

Name: dapA [H]

Synonym: Blon_2034

Alternate gene names: 213692893

Gene position: 2227544-2226639 (Counterclockwise)

Preceding gene: 213692894

Following gene: 213692892

Centisome position: 78.64

GC content: 62.47

Gene sequence:

>906_bases
ATGAGCGAGCATGACATGCACCTTCTTGAGCCAGCACCTTTCGGCCGCATTCTGCCGGCTATGGTCACCCCGATGAAATC
CGACGGCAGCGTCGATTTCGCCGCCGCGCAGAAGCTCGCCAAATACCTCGTCGCCGATGGCGCGGATGGTCTGGTGGTCA
ATGGCACCACCGGTGAATCGCCCGTCACCCATATGGATGAGAAGGTCGAGCTGGTCAGGGCCGTCAAGGAGGTCGTCGAC
GTTCCGGTGATTTCCGGCGCCGGCTCCAACGACACCGCACACACCGTGCGTATGGTCGAACAGACTCAGGAAGCGGGCGC
CGACGCGGTGCTCGTCGTCATGCCTTACTATTCCCGCCCCTCGCAGGACGGTATCGTCGGCCACTACAAGGCCGTCGACG
AATCCGCCGAAAAGCCGATCATCGTCTACGATGTTCCCGGCCGTACCGGCTTGAAGGTCAAGGTCGAAACCTACGACCGA
CTGGCCGGACTTGAACACGTCAAGGCTGTCAAGGACGCCACCGGCGATCTTGCAGCCGCAGTGGAGAAGCAGCAGCGCAC
CGGCCTCGCCTGGTATTCCGGCGATGACGGCCTGTTCCTGCCGTTCCTCTCCATCGGTGCCGTCGGCATCATTTCGGTGA
TTGCCCACGTCGCCTCCAACCCCATGCAGCAGCTTGTCCAGGCATTCGATCGCGGCGATATCACCACCGCCCGTCGCCTC
GCCAACCAGCTCGCCCCCCTTGTCCACGCGTTGAATGGCGACGGTTATCAGGCCGTCATGGCCAAGGCTGCGCTCAAGGT
CAAGGGTGTTATCCCCTCCACCACCATGCGTCTGCCGAACATCGGTCCCGACGCCACTCAGCTTGACAAGGCTGAAGAGG
GCATGCGCGCTGCCGGACTGCTGTAA

Upstream 100 bases:

>100_bases
CACGGCATTGCCGCCGGTTCCGGTCATAATGCCACGCATGCAGCAACAATCAAGGTACGTAATATATTAAGAGTCCACAA
TGGGAAGTACGGTGAACACT

Downstream 100 bases:

>100_bases
GCCCGAAACGCTGCATACGGGTTGCCAGCCCGCCGCCCCTGCATGACAGAGCAGAGGCACCACAACAGAAATCCCAAAAA
GGTTATGGCACAAGAACAAA

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 301; Mature: 300

Protein sequence:

>301_residues
MSEHDMHLLEPAPFGRILPAMVTPMKSDGSVDFAAAQKLAKYLVADGADGLVVNGTTGESPVTHMDEKVELVRAVKEVVD
VPVISGAGSNDTAHTVRMVEQTQEAGADAVLVVMPYYSRPSQDGIVGHYKAVDESAEKPIIVYDVPGRTGLKVKVETYDR
LAGLEHVKAVKDATGDLAAAVEKQQRTGLAWYSGDDGLFLPFLSIGAVGIISVIAHVASNPMQQLVQAFDRGDITTARRL
ANQLAPLVHALNGDGYQAVMAKAALKVKGVIPSTTMRLPNIGPDATQLDKAEEGMRAAGLL

Sequences:

>Translated_301_residues
MSEHDMHLLEPAPFGRILPAMVTPMKSDGSVDFAAAQKLAKYLVADGADGLVVNGTTGESPVTHMDEKVELVRAVKEVVD
VPVISGAGSNDTAHTVRMVEQTQEAGADAVLVVMPYYSRPSQDGIVGHYKAVDESAEKPIIVYDVPGRTGLKVKVETYDR
LAGLEHVKAVKDATGDLAAAVEKQQRTGLAWYSGDDGLFLPFLSIGAVGIISVIAHVASNPMQQLVQAFDRGDITTARRL
ANQLAPLVHALNGDGYQAVMAKAALKVKGVIPSTTMRLPNIGPDATQLDKAEEGMRAAGLL
>Mature_300_residues
SEHDMHLLEPAPFGRILPAMVTPMKSDGSVDFAAAQKLAKYLVADGADGLVVNGTTGESPVTHMDEKVELVRAVKEVVDV
PVISGAGSNDTAHTVRMVEQTQEAGADAVLVVMPYYSRPSQDGIVGHYKAVDESAEKPIIVYDVPGRTGLKVKVETYDRL
AGLEHVKAVKDATGDLAAAVEKQQRTGLAWYSGDDGLFLPFLSIGAVGIISVIAHVASNPMQQLVQAFDRGDITTARRLA
NQLAPLVHALNGDGYQAVMAKAALKVKGVIPSTTMRLPNIGPDATQLDKAEEGMRAAGLL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=235, Percent_Identity=28.0851063829787, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI13540533, Length=297, Percent_Identity=24.2424242424242, Blast_Score=92, Evalue=6e-19,
Organism=Escherichia coli, GI1788823, Length=286, Percent_Identity=35.3146853146853, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1789620, Length=239, Percent_Identity=29.2887029288703, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI87082415, Length=299, Percent_Identity=28.0936454849498, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1786463, Length=285, Percent_Identity=27.3684210526316, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31875; Mature: 31744

Theoretical pI: Translated: 5.36; Mature: 5.36

Prosite motif: PS00665 DHDPS_1 ; PS00666 DHDPS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHDMHLLEPAPFGRILPAMVTPMKSDGSVDFAAAQKLAKYLVADGADGLVVNGTTGES
CCCCCCEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCC
PVTHMDEKVELVRAVKEVVDVPVISGAGSNDTAHTVRMVEQTQEAGADAVLVVMPYYSRP
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCC
SQDGIVGHYKAVDESAEKPIIVYDVPGRTGLKVKVETYDRLAGLEHVKAVKDATGDLAAA
CCCCCEEHHHHHHHCCCCCEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHH
VEKQQRTGLAWYSGDDGLFLPFLSIGAVGIISVIAHVASNPMQQLVQAFDRGDITTARRL
HHHHHHCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
ANQLAPLVHALNGDGYQAVMAKAALKVKGVIPSTTMRLPNIGPDATQLDKAEEGMRAAGL
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCC
L
C
>Mature Secondary Structure 
SEHDMHLLEPAPFGRILPAMVTPMKSDGSVDFAAAQKLAKYLVADGADGLVVNGTTGES
CCCCCEEECCCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCC
PVTHMDEKVELVRAVKEVVDVPVISGAGSNDTAHTVRMVEQTQEAGADAVLVVMPYYSRP
CCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCC
SQDGIVGHYKAVDESAEKPIIVYDVPGRTGLKVKVETYDRLAGLEHVKAVKDATGDLAAA
CCCCCEEHHHHHHHCCCCCEEEEECCCCCCCEEEEEHHHHHHHHHHHHHHHHCCCHHHHH
VEKQQRTGLAWYSGDDGLFLPFLSIGAVGIISVIAHVASNPMQQLVQAFDRGDITTARRL
HHHHHHCCEEEEECCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
ANQLAPLVHALNGDGYQAVMAKAALKVKGVIPSTTMRLPNIGPDATQLDKAEEGMRAAGL
HHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA