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The map label for this gene is yisV [H]

Identifier: 213692851

GI number: 213692851

Start: 2171774

End: 2173285

Strand: Reverse

Name: yisV [H]

Synonym: Blon_1992

Alternate gene names: 213692851

Gene position: 2173285-2171774 (Counterclockwise)

Preceding gene: 213692852

Following gene: 213692850

Centisome position: 76.72

GC content: 58.86

Gene sequence:

>1512_bases
ATGCAGCTTGAGCTGAATCGACGCAGCAAGGTGCCGATGTACCGGCAGCTGGCTGCCGAGCTGCGTGAACAGATCGTCTC
CGGCGCGATGGCCGAGGGCTACCGCCTGCCTCCCGAACGCGAGCTGTCCTCACGTCTCGAAGTCAATCGCACCACGGTGT
TGCAGGCGTATCAGCAGCTCAAGGACGAAGGTCTTATCGCCTCCAAAGTCGGCAAAGGCACGTTCGTGCTGCCGTTGCAG
CATACTGAGACTGCCCGGATTCCTGTAGTGAGACATAAGCCGATTGACGAGGAGCCGAAACCGAGCGTCGTGCGTCCTCC
ATGGTCGGTGTTGTTCTCTGATTATTCCAACCGGTTTACCTACCATGACATCGCCTCGGCCGAGCGGGCGCAGCGCGGCG
ACACCATTATTGACTTCGCCACCGGTTCGCCGAACCCGGCGGATATCCCGGACGATTTGTTGCGCAAGGTGAGCATCGAG
GCGTTCGAATCGCGGGAATTCGACGGCCAACCGGAATCACCTATCGAGGGATTCGAAGAGTTGCGTGCGCTACTTGCCGA
ACATATGCGCACACGAGGCGTACAATGCGGCGTCCGCAACGTGATGGTGCTCTCCGGCTCCGAGCAGGGCATCGACCTCA
TCGTGCGCGCGTTCATCAACCCCGGCGACTGCGTGCTGGTCGAACAATCCACATTCTTCCCGGCATTGCAGACCTTCCGC
TCGGCGGATGCGCGCATCATCGGCGTTCCAGTGGACGAGCACGGTATGCGTACAGACCTGTTGGACGGCTATTGCGCGCG
ATTCCGGCCCAAGCTCATCTACACCGTCCCGACGTTCCAAAACCCCACCGGTACCACGCTGCCGCCCGAACGACGCAGCG
AACTCATCGACGTGGCGCGGCGCTATCAGTGTCTGATCGTGGAAGACGATGCTTACGGCGATTTGTGGTACGGCGGGGGA
TCATCTGACGCACATCGCCCCATACCGCTTAAGGGCATGGAGAATGCGGGATACGTGATGTATTTGTCGACGTTCTCGAA
AACCGTCACTTCGGGCCTGCGCACGGGATGGGTTGTGGCCGACCCGCATGTGATCAACCGGCTGGCGGCTCTGCGGCGCA
TGGTCGACCAGCATACGAGCACGTCATCGCAGCGCATCTGCCTGGAACTGCTTAAAGAAGGCCGCGTCGCCGAACATTTG
CACGGTTTGATTAAGGCTTACCGCATTCGACGAGATGCAGCAATCGCAGCATTGGAACAGTATGCGCCGGATGAAGTGTA
TTGGACCGTGCCTGCAGGTGGCTACTATATTTGGGTTTCCTTACCGGACGGCGTGCGCTCTCTGGATGTATTGGAATCCT
GCCGTTCCCAAGGCGTCACGTTCATGCCGGGCAGTGTGTTCGACGTTGACGAAATGGATGATTCCCACATCCGTCTCAAC
TTTGTGCGCCCGGATGCTGCTGACATTGATACCGGCATTCGAATCATTGGCGAGACGATAGCACAGATGTAG

Upstream 100 bases:

>100_bases
CACGGACGATACCCGCATCCACGAGCTCTTCCTGTCGCTGTAGTCGATTCGTCTGCCGCTAGACTGGTATCCGACTGACG
AATCAAGGAGACGATCTGCC

Downstream 100 bases:

>100_bases
CCAAGTGACTGGCTCATTGCGGTTGTCGAGTTTTTTTGATGGCTACATACCCACATCGATGAGTGCATTCGACGAATGAA
TAAGCGAGGAAGCCATCATC

Product: transcriptional regulator, GntR family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MQLELNRRSKVPMYRQLAAELREQIVSGAMAEGYRLPPERELSSRLEVNRTTVLQAYQQLKDEGLIASKVGKGTFVLPLQ
HTETARIPVVRHKPIDEEPKPSVVRPPWSVLFSDYSNRFTYHDIASAERAQRGDTIIDFATGSPNPADIPDDLLRKVSIE
AFESREFDGQPESPIEGFEELRALLAEHMRTRGVQCGVRNVMVLSGSEQGIDLIVRAFINPGDCVLVEQSTFFPALQTFR
SADARIIGVPVDEHGMRTDLLDGYCARFRPKLIYTVPTFQNPTGTTLPPERRSELIDVARRYQCLIVEDDAYGDLWYGGG
SSDAHRPIPLKGMENAGYVMYLSTFSKTVTSGLRTGWVVADPHVINRLAALRRMVDQHTSTSSQRICLELLKEGRVAEHL
HGLIKAYRIRRDAAIAALEQYAPDEVYWTVPAGGYYIWVSLPDGVRSLDVLESCRSQGVTFMPGSVFDVDEMDDSHIRLN
FVRPDAADIDTGIRIIGETIAQM

Sequences:

>Translated_503_residues
MQLELNRRSKVPMYRQLAAELREQIVSGAMAEGYRLPPERELSSRLEVNRTTVLQAYQQLKDEGLIASKVGKGTFVLPLQ
HTETARIPVVRHKPIDEEPKPSVVRPPWSVLFSDYSNRFTYHDIASAERAQRGDTIIDFATGSPNPADIPDDLLRKVSIE
AFESREFDGQPESPIEGFEELRALLAEHMRTRGVQCGVRNVMVLSGSEQGIDLIVRAFINPGDCVLVEQSTFFPALQTFR
SADARIIGVPVDEHGMRTDLLDGYCARFRPKLIYTVPTFQNPTGTTLPPERRSELIDVARRYQCLIVEDDAYGDLWYGGG
SSDAHRPIPLKGMENAGYVMYLSTFSKTVTSGLRTGWVVADPHVINRLAALRRMVDQHTSTSSQRICLELLKEGRVAEHL
HGLIKAYRIRRDAAIAALEQYAPDEVYWTVPAGGYYIWVSLPDGVRSLDVLESCRSQGVTFMPGSVFDVDEMDDSHIRLN
FVRPDAADIDTGIRIIGETIAQM
>Mature_503_residues
MQLELNRRSKVPMYRQLAAELREQIVSGAMAEGYRLPPERELSSRLEVNRTTVLQAYQQLKDEGLIASKVGKGTFVLPLQ
HTETARIPVVRHKPIDEEPKPSVVRPPWSVLFSDYSNRFTYHDIASAERAQRGDTIIDFATGSPNPADIPDDLLRKVSIE
AFESREFDGQPESPIEGFEELRALLAEHMRTRGVQCGVRNVMVLSGSEQGIDLIVRAFINPGDCVLVEQSTFFPALQTFR
SADARIIGVPVDEHGMRTDLLDGYCARFRPKLIYTVPTFQNPTGTTLPPERRSELIDVARRYQCLIVEDDAYGDLWYGGG
SSDAHRPIPLKGMENAGYVMYLSTFSKTVTSGLRTGWVVADPHVINRLAALRRMVDQHTSTSSQRICLELLKEGRVAEHL
HGLIKAYRIRRDAAIAALEQYAPDEVYWTVPAGGYYIWVSLPDGVRSLDVLESCRSQGVTFMPGSVFDVDEMDDSHIRLN
FVRPDAADIDTGIRIIGETIAQM

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=400, Percent_Identity=28.75, Blast_Score=155, Evalue=7e-38,
Organism=Homo sapiens, GI33469970, Length=400, Percent_Identity=28.75, Blast_Score=155, Evalue=7e-38,
Organism=Escherichia coli, GI1787710, Length=492, Percent_Identity=25.8130081300813, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI1790797, Length=496, Percent_Identity=25.4032258064516, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1788722, Length=362, Percent_Identity=24.3093922651934, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321236, Length=335, Percent_Identity=27.1641791044776, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6321000, Length=244, Percent_Identity=30.327868852459, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6321929, Length=317, Percent_Identity=23.6593059936909, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21356535, Length=364, Percent_Identity=24.7252747252747, Blast_Score=102, Evalue=5e-22,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 56394; Mature: 56394

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLELNRRSKVPMYRQLAAELREQIVSGAMAEGYRLPPERELSSRLEVNRTTVLQAYQQL
CCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHH
KDEGLIASKVGKGTFVLPLQHTETARIPVVRHKPIDEEPKPSVVRPPWSVLFSDYSNRFT
HHCCCEEEECCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEE
YHDIASAERAQRGDTIIDFATGSPNPADIPDDLLRKVSIEAFESREFDGQPESPIEGFEE
EHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LRALLAEHMRTRGVQCGVRNVMVLSGSEQGIDLIVRAFINPGDCVLVEQSTFFPALQTFR
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHH
SADARIIGVPVDEHGMRTDLLDGYCARFRPKLIYTVPTFQNPTGTTLPPERRSELIDVAR
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
RYQCLIVEDDAYGDLWYGGGSSDAHRPIPLKGMENAGYVMYLSTFSKTVTSGLRTGWVVA
HCEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCEEE
DPHVINRLAALRRMVDQHTSTSSQRICLELLKEGRVAEHLHGLIKAYRIRRDAAIAALEQ
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YAPDEVYWTVPAGGYYIWVSLPDGVRSLDVLESCRSQGVTFMPGSVFDVDEMDDSHIRLN
CCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCEECCCCEEECCCCCCCEEEEE
FVRPDAADIDTGIRIIGETIAQM
EECCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLELNRRSKVPMYRQLAAELREQIVSGAMAEGYRLPPERELSSRLEVNRTTVLQAYQQL
CCCCCCCCCCCCHHHHHHHHHHHHHHHCHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHH
KDEGLIASKVGKGTFVLPLQHTETARIPVVRHKPIDEEPKPSVVRPPWSVLFSDYSNRFT
HHCCCEEEECCCCEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHCCCEE
YHDIASAERAQRGDTIIDFATGSPNPADIPDDLLRKVSIEAFESREFDGQPESPIEGFEE
EHHHHHHHHHHCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
LRALLAEHMRTRGVQCGVRNVMVLSGSEQGIDLIVRAFINPGDCVLVEQSTFFPALQTFR
HHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHHH
SADARIIGVPVDEHGMRTDLLDGYCARFRPKLIYTVPTFQNPTGTTLPPERRSELIDVAR
CCCCEEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHHHHHHHH
RYQCLIVEDDAYGDLWYGGGSSDAHRPIPLKGMENAGYVMYLSTFSKTVTSGLRTGWVVA
HCEEEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHCCCEEE
DPHVINRLAALRRMVDQHTSTSSQRICLELLKEGRVAEHLHGLIKAYRIRRDAAIAALEQ
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHH
YAPDEVYWTVPAGGYYIWVSLPDGVRSLDVLESCRSQGVTFMPGSVFDVDEMDDSHIRLN
CCCCCEEEEECCCCEEEEEECCCCHHHHHHHHHHHHCCCEECCCCEEECCCCCCCEEEEE
FVRPDAADIDTGIRIIGETIAQM
EECCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]