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The map label for this gene is pheS

Identifier: 213692750

GI number: 213692750

Start: 2055010

End: 2056077

Strand: Reverse

Name: pheS

Synonym: Blon_1884

Alternate gene names: 213692750

Gene position: 2056077-2055010 (Counterclockwise)

Preceding gene: 213692751

Following gene: 213692749

Centisome position: 72.58

GC content: 63.86

Gene sequence:

>1068_bases
GTGGCAGAACAAATGGTGTTCGACGCCGACCAGGTGACCGCTGAGGTTGCCGAGGGCATCGAGAAAATCCAGAACGCCTC
CAACCTGGAGGAGCTCAAGGCCATCAAGACGACGTACGCAGGTGCCGATTCGGCGATGACCAAGGCCAGCAAGGCCATTG
GCTCCCTGCCCGCCGACCAGAAGAAGGAAGCCGGCAAGCTCATGGGCAAGCTGCGCGCCGACTTCGGCCGTGCCTATGGT
CCCAAGGAGGTCGAGCTCAAGGAAGCCGCCGAGAAGGCCGCGCTTGCCGCCGAAACCGTGGATATGACGCTGCCGGTGAA
CCGTAAGCCTCTGGGCGCCCGTCACCCGCTGCCTAAGCTGATGGAGGACGTCGAGGACTTCTTCATCTCCATGGGTTGGC
AGATCTCCTCCGGCCTGGAAATCGAAGCCGAATGGTACAACTTCGACTCCCTGAATTTCGGCCCGGACCATCCGGCCCGC
CAGATGCAGGACACCTTCTACGTCAAGGGCAATCAGGCCAAGGACGCCGCCGGTTTCGTCGGCTCCAACATGGTGGTGCG
TACGCAGACCTCCTCCGATCAGGTCCGTGCCCTCCTGACCCGTGGCGTGCCGCTGTACATCGCGTCCCCGGGCCGTGTGT
TCCGCACCGATGAGCTGGACGCCACCCATACTCCGGTGTTCCACCAGTGCGAAGCCCTCGCCGTCGACAAGCACCTTACT
ATGGCCGACCTGAAGGGCGTGTTGGACAAGCTCGCCGTCGCCATGTTCGGCCCTGAAGCCAAGACGCGCCTGCGCCCGAG
CTACTTCCCGTTCACTGAGCCGAGCGCCGAACTCGACCTGTGGTTCCCCGACAAGAAGGGCGGCCCCGGCTGGCTCGAGT
GGGGCGGCTGCGGCATGGTGAACCCGAACGTGCTGAAGTCCGCCGGCATCGACCCGGACGTCTACACCGGTTTCGCCTTC
GGCGTCGGCATGGAGCGCACGCTCCTGCTGCGCAGCGACATCAACGACATGCACGACCTGGTCGAAGGCGACGTGCGTTT
CGCCGAACAGTTTGTGATGGGGGAGTGA

Upstream 100 bases:

>100_bases
TGATGCTGATGTCGCTGTCTATGTCGGGTCATGTTGAAAGAATGTGAAACCGGTAAAAACGCTGTGAAACGCTGAGAAAA
CATCAGACGAAAGGGTTCTC

Downstream 100 bases:

>100_bases
TTCAGCCATGCCTATGATTGATATCGATTGGCTCAAGGACCATGTCGAGGTTCCTGAAGGCCTGACCTACGAACAGCTCG
CCAAGGACCTTGTCAAGGTG

Product: phenylalanyl-tRNA synthetase subunit alpha

Products: NA

Alternate protein names: Phenylalanine--tRNA ligase alpha chain; PheRS

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MAEQMVFDADQVTAEVAEGIEKIQNASNLEELKAIKTTYAGADSAMTKASKAIGSLPADQKKEAGKLMGKLRADFGRAYG
PKEVELKEAAEKAALAAETVDMTLPVNRKPLGARHPLPKLMEDVEDFFISMGWQISSGLEIEAEWYNFDSLNFGPDHPAR
QMQDTFYVKGNQAKDAAGFVGSNMVVRTQTSSDQVRALLTRGVPLYIASPGRVFRTDELDATHTPVFHQCEALAVDKHLT
MADLKGVLDKLAVAMFGPEAKTRLRPSYFPFTEPSAELDLWFPDKKGGPGWLEWGGCGMVNPNVLKSAGIDPDVYTGFAF
GVGMERTLLLRSDINDMHDLVEGDVRFAEQFVMGE

Sequences:

>Translated_355_residues
MAEQMVFDADQVTAEVAEGIEKIQNASNLEELKAIKTTYAGADSAMTKASKAIGSLPADQKKEAGKLMGKLRADFGRAYG
PKEVELKEAAEKAALAAETVDMTLPVNRKPLGARHPLPKLMEDVEDFFISMGWQISSGLEIEAEWYNFDSLNFGPDHPAR
QMQDTFYVKGNQAKDAAGFVGSNMVVRTQTSSDQVRALLTRGVPLYIASPGRVFRTDELDATHTPVFHQCEALAVDKHLT
MADLKGVLDKLAVAMFGPEAKTRLRPSYFPFTEPSAELDLWFPDKKGGPGWLEWGGCGMVNPNVLKSAGIDPDVYTGFAF
GVGMERTLLLRSDINDMHDLVEGDVRFAEQFVMGE
>Mature_354_residues
AEQMVFDADQVTAEVAEGIEKIQNASNLEELKAIKTTYAGADSAMTKASKAIGSLPADQKKEAGKLMGKLRADFGRAYGP
KEVELKEAAEKAALAAETVDMTLPVNRKPLGARHPLPKLMEDVEDFFISMGWQISSGLEIEAEWYNFDSLNFGPDHPARQ
MQDTFYVKGNQAKDAAGFVGSNMVVRTQTSSDQVRALLTRGVPLYIASPGRVFRTDELDATHTPVFHQCEALAVDKHLTM
ADLKGVLDKLAVAMFGPEAKTRLRPSYFPFTEPSAELDLWFPDKKGGPGWLEWGGCGMVNPNVLKSAGIDPDVYTGFAFG
VGMERTLLLRSDINDMHDLVEGDVRFAEQFVMGE

Specific function: Unknown

COG id: COG0016

COG function: function code J; Phenylalanyl-tRNA synthetase alpha subunit

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha chain type 1 subfamily

Homologues:

Organism=Homo sapiens, GI4758340, Length=263, Percent_Identity=31.1787072243346, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI5729820, Length=245, Percent_Identity=31.0204081632653, Blast_Score=109, Evalue=4e-24,
Organism=Escherichia coli, GI1788007, Length=336, Percent_Identity=40.1785714285714, Blast_Score=266, Evalue=2e-72,
Organism=Caenorhabditis elegans, GI32563657, Length=265, Percent_Identity=32.0754716981132, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17508957, Length=265, Percent_Identity=32.0754716981132, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI32566635, Length=298, Percent_Identity=28.8590604026846, Blast_Score=104, Evalue=6e-23,
Organism=Saccharomyces cerevisiae, GI6321087, Length=262, Percent_Identity=30.5343511450382, Blast_Score=123, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6325304, Length=96, Percent_Identity=39.5833333333333, Blast_Score=75, Evalue=2e-14,
Organism=Drosophila melanogaster, GI17137424, Length=303, Percent_Identity=29.042904290429, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI18858079, Length=282, Percent_Identity=28.3687943262411, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYFA_BIFLI (B7GTP9)

Other databases:

- EMBL:   CP001095
- RefSeq:   YP_002323336.1
- GeneID:   7055316
- GenomeReviews:   CP001095_GR
- KEGG:   bln:Blon_1884
- HOGENOM:   HBG284353
- ProtClustDB:   PRK00488
- GO:   GO:0005737
- HAMAP:   MF_00281
- InterPro:   IPR006195
- InterPro:   IPR004529
- InterPro:   IPR004188
- InterPro:   IPR022911
- InterPro:   IPR002319
- InterPro:   IPR010978
- PANTHER:   PTHR11538
- TIGRFAMs:   TIGR00468

Pfam domain/function: PF02912 Phe_tRNA-synt_N; PF01409 tRNA-synt_2d; SSF46589 tRNA_binding_arm

EC number: =6.1.1.20

Molecular weight: Translated: 38917; Mature: 38785

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEQMVFDADQVTAEVAEGIEKIQNASNLEELKAIKTTYAGADSAMTKASKAIGSLPADQ
CCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHH
KKEAGKLMGKLRADFGRAYGPKEVELKEAAEKAALAAETVDMTLPVNRKPLGARHPLPKL
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHH
MEDVEDFFISMGWQISSGLEIEAEWYNFDSLNFGPDHPARQMQDTFYVKGNQAKDAAGFV
HHHHHHHHHHCCCEECCCCEEEEEEECCCCCCCCCCCHHHHHCCEEEEECCCCCCHHHHC
GSNMVVRTQTSSDQVRALLTRGVPLYIASPGRVFRTDELDATHTPVFHQCEALAVDKHLT
CCCEEEEECCCHHHHHHHHHCCCEEEEECCCCEEECCCCCCCCCCHHHHHHHHHHCCCHH
MADLKGVLDKLAVAMFGPEAKTRLRPSYFPFTEPSAELDLWFPDKKGGPGWLEWGGCGMV
HHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEECCCCCC
NPNVLKSAGIDPDVYTGFAFGVGMERTLLLRSDINDMHDLVEGDVRFAEQFVMGE
CCHHHHHCCCCCHHHHHHHHCCCCCCEEEEHHCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AEQMVFDADQVTAEVAEGIEKIQNASNLEELKAIKTTYAGADSAMTKASKAIGSLPADQ
CCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHH
KKEAGKLMGKLRADFGRAYGPKEVELKEAAEKAALAAETVDMTLPVNRKPLGARHPLPKL
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCHHHH
MEDVEDFFISMGWQISSGLEIEAEWYNFDSLNFGPDHPARQMQDTFYVKGNQAKDAAGFV
HHHHHHHHHHCCCEECCCCEEEEEEECCCCCCCCCCCHHHHHCCEEEEECCCCCCHHHHC
GSNMVVRTQTSSDQVRALLTRGVPLYIASPGRVFRTDELDATHTPVFHQCEALAVDKHLT
CCCEEEEECCCHHHHHHHHHCCCEEEEECCCCEEECCCCCCCCCCHHHHHHHHHHCCCHH
MADLKGVLDKLAVAMFGPEAKTRLRPSYFPFTEPSAELDLWFPDKKGGPGWLEWGGCGMV
HHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEECCCCCC
NPNVLKSAGIDPDVYTGFAFGVGMERTLLLRSDINDMHDLVEGDVRFAEQFVMGE
CCHHHHHCCCCCHHHHHHHHCCCCCCEEEEHHCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA