Click here to switch to the map view.

The map label for this gene is argG [H]

Identifier: 213692741

GI number: 213692741

Start: 2044094

End: 2045332

Strand: Reverse

Name: argG [H]

Synonym: Blon_1875

Alternate gene names: 213692741

Gene position: 2045332-2044094 (Counterclockwise)

Preceding gene: 213692742

Following gene: 213692740

Centisome position: 72.2

GC content: 63.28

Gene sequence:

>1239_bases
ATGGCAGATAACAAGCGCATTGTTCTGGCCTACTCCGGCGGTCTTGACACCTCCGTCGCCATCTCGTACCTGAAGGAGCG
TACCGGCAAGGACGTCGTGGCCGTGTCCCTCGACGTCGGCCAGGGCGGCGAAAGCCTCGAGACCATCAAGCAGCGCGCCC
TCGCCTGCGGAGCCGTCGAATCCTACGTGGTCGATGCCCGTGACGAGTTCGCCAACGAATATTGCATGAAGGCCCTCAAG
GCCAACGCCATGTACGAAGGCGTCTACCCGCTGGTCTCCGCCATCTCCCGTCCGCTGATCTCCAAGCACCTCGTGCGCGC
CGCCCACCAGTTCGGCGCCGACACCATCTCCCACGGTTGCACCGGCAAGGGCAACGACCAGGTTCGTTTCGAGGTCTCCA
TTGCCTCCATCGACCCGACGCTGAAGGCCATCAGCCCGATTCGTGACCTGTCCCTGACCCGCGACGTCGAGATCGCGTTC
GCCAAGGAGCACAAGTTGCCGATCACCCAGACCGAGAAGTCCCCGTACTCCATCGACCAGAACGTATGGGGCCGCGCCAT
TGAGACCGGCTTCCTTGAGGATCCGTGGAACGGCCCGACCAAGGACTGCTACTCCTACACCGACGACCCGGCCTTCCCGC
CGGTCGAAGATGAAGTCGTCATCGAGTTCAAGGAAGGTGTGCCGGTCAAGATCGACGGACGTGACGTCACCCCGCTGCAG
GCCATCGAGGAGATGAACCGCCGCGCCGGAGCCCAGGGCATCGGCCGCATCGACCTCATCGAGGACCGCCTGGTCGGCAT
CAAGTCCCGCGAGCTGTACGAGGCTCCGGGTGCCGTGGCCCTGATTACCGCTCATCAGGAGCTTGAGAACTGCTGCCTCG
AACGCGAACAGCACCGCATCAAGCGCGACATCGACAAGCGCTGGGGCGAGCTGGTTTACGATGCGCAGTGGTTCTCCCCG
GCAACCCAGTCGCTCAACGCCTTCATCGAAGACACCCAGAAGTACGTGTCCGGTGAGATTCGCATGGTCCTGCACGGCGG
TCGCGCCGTCGTGACCGGCCGTCGTTCCGACTCCTCGCTGTACGACTACAAGCTCGCCACCTACGATTCCGGCGATACCT
TCGACCAGAAGTCCTCCAACGGCTTCATCGACATCTACGGCCTGCCGTCCCGCGTGGCCGCAGCGCGCGACGTCAAGTTC
GGCAACGGCATCGAGGTCCCGAAGAACACCGTCGAGTAA

Upstream 100 bases:

>100_bases
AGCCTCGCCTCCAAATAACCAACACGCCGTGCATAAATATACAGTCCTCTGTATATACTTGCATCAGTTTGTTTTTTAGA
CCTTGAACGAAAGGGAACCA

Downstream 100 bases:

>100_bases
TTCTTACTCAGTCGCCCCCGCTGCGAGGCTGTCGGCATAGCTGACTGGGAGTAGTCTTTGAAAGGACTGTCCTCAGTCAC
ACTCCATGTGACAGCCCTCG

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MADNKRIVLAYSGGLDTSVAISYLKERTGKDVVAVSLDVGQGGESLETIKQRALACGAVESYVVDARDEFANEYCMKALK
ANAMYEGVYPLVSAISRPLISKHLVRAAHQFGADTISHGCTGKGNDQVRFEVSIASIDPTLKAISPIRDLSLTRDVEIAF
AKEHKLPITQTEKSPYSIDQNVWGRAIETGFLEDPWNGPTKDCYSYTDDPAFPPVEDEVVIEFKEGVPVKIDGRDVTPLQ
AIEEMNRRAGAQGIGRIDLIEDRLVGIKSRELYEAPGAVALITAHQELENCCLEREQHRIKRDIDKRWGELVYDAQWFSP
ATQSLNAFIEDTQKYVSGEIRMVLHGGRAVVTGRRSDSSLYDYKLATYDSGDTFDQKSSNGFIDIYGLPSRVAAARDVKF
GNGIEVPKNTVE

Sequences:

>Translated_412_residues
MADNKRIVLAYSGGLDTSVAISYLKERTGKDVVAVSLDVGQGGESLETIKQRALACGAVESYVVDARDEFANEYCMKALK
ANAMYEGVYPLVSAISRPLISKHLVRAAHQFGADTISHGCTGKGNDQVRFEVSIASIDPTLKAISPIRDLSLTRDVEIAF
AKEHKLPITQTEKSPYSIDQNVWGRAIETGFLEDPWNGPTKDCYSYTDDPAFPPVEDEVVIEFKEGVPVKIDGRDVTPLQ
AIEEMNRRAGAQGIGRIDLIEDRLVGIKSRELYEAPGAVALITAHQELENCCLEREQHRIKRDIDKRWGELVYDAQWFSP
ATQSLNAFIEDTQKYVSGEIRMVLHGGRAVVTGRRSDSSLYDYKLATYDSGDTFDQKSSNGFIDIYGLPSRVAAARDVKF
GNGIEVPKNTVE
>Mature_411_residues
ADNKRIVLAYSGGLDTSVAISYLKERTGKDVVAVSLDVGQGGESLETIKQRALACGAVESYVVDARDEFANEYCMKALKA
NAMYEGVYPLVSAISRPLISKHLVRAAHQFGADTISHGCTGKGNDQVRFEVSIASIDPTLKAISPIRDLSLTRDVEIAFA
KEHKLPITQTEKSPYSIDQNVWGRAIETGFLEDPWNGPTKDCYSYTDDPAFPPVEDEVVIEFKEGVPVKIDGRDVTPLQA
IEEMNRRAGAQGIGRIDLIEDRLVGIKSRELYEAPGAVALITAHQELENCCLEREQHRIKRDIDKRWGELVYDAQWFSPA
TQSLNAFIEDTQKYVSGEIRMVLHGGRAVVTGRRSDSSLYDYKLATYDSGDTFDQKSSNGFIDIYGLPSRVAAARDVKFG
NGIEVPKNTVE

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=399, Percent_Identity=37.844611528822, Blast_Score=261, Evalue=6e-70,
Organism=Homo sapiens, GI16950633, Length=399, Percent_Identity=37.844611528822, Blast_Score=261, Evalue=6e-70,
Organism=Escherichia coli, GI1789563, Length=391, Percent_Identity=26.3427109974425, Blast_Score=107, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6324514, Length=400, Percent_Identity=34.25, Blast_Score=235, Evalue=8e-63,
Organism=Drosophila melanogaster, GI21358151, Length=394, Percent_Identity=36.2944162436548, Blast_Score=243, Evalue=1e-64,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 45521; Mature: 45389

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADNKRIVLAYSGGLDTSVAISYLKERTGKDVVAVSLDVGQGGESLETIKQRALACGAVE
CCCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
SYVVDARDEFANEYCMKALKANAMYEGVYPLVSAISRPLISKHLVRAAHQFGADTISHGC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
TGKGNDQVRFEVSIASIDPTLKAISPIRDLSLTRDVEIAFAKEHKLPITQTEKSPYSIDQ
CCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCEECCCCCCCCCH
NVWGRAIETGFLEDPWNGPTKDCYSYTDDPAFPPVEDEVVIEFKEGVPVKIDGRDVTPLQ
HHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCHHH
AIEEMNRRAGAQGIGRIDLIEDRLVGIKSRELYEAPGAVALITAHQELENCCLEREQHRI
HHHHHHHHCCCCCCCCEEEHHHHHCCCCCCHHHCCCCCEEEEECHHHHHHHHHHHHHHHH
KRDIDKRWGELVYDAQWFSPATQSLNAFIEDTQKYVSGEIRMVLHGGRAVVTGRRSDSSL
HHHHHHHHHHHEECCHHCCHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCCCCE
YDYKLATYDSGDTFDQKSSNGFIDIYGLPSRVAAARDVKFGNGIEVPKNTVE
EEEEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ADNKRIVLAYSGGLDTSVAISYLKERTGKDVVAVSLDVGQGGESLETIKQRALACGAVE
CCCCEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHH
SYVVDARDEFANEYCMKALKANAMYEGVYPLVSAISRPLISKHLVRAAHQFGADTISHGC
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
TGKGNDQVRFEVSIASIDPTLKAISPIRDLSLTRDVEIAFAKEHKLPITQTEKSPYSIDQ
CCCCCCEEEEEEEEECCCCHHHHHHHHHHCCCCCCEEEEEECCCCCCCEECCCCCCCCCH
NVWGRAIETGFLEDPWNGPTKDCYSYTDDPAFPPVEDEVVIEFKEGVPVKIDGRDVTPLQ
HHHHHHHHCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCEEEEECCCCEEEECCCCCCHHH
AIEEMNRRAGAQGIGRIDLIEDRLVGIKSRELYEAPGAVALITAHQELENCCLEREQHRI
HHHHHHHHCCCCCCCCEEEHHHHHCCCCCCHHHCCCCCEEEEECHHHHHHHHHHHHHHHH
KRDIDKRWGELVYDAQWFSPATQSLNAFIEDTQKYVSGEIRMVLHGGRAVVTGRRSDSSL
HHHHHHHHHHHEECCHHCCHHHHHHHHHHHHHHHHHCCCEEEEEECCEEEEEECCCCCCE
YDYKLATYDSGDTFDQKSSNGFIDIYGLPSRVAAARDVKFGNGIEVPKNTVE
EEEEEEEECCCCCCCCCCCCCEEEEECCCHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA