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The map label for this gene is coaE [H]

Identifier: 213692620

GI number: 213692620

Start: 1926497

End: 1927114

Strand: Reverse

Name: coaE [H]

Synonym: Blon_1753

Alternate gene names: 213692620

Gene position: 1927114-1926497 (Counterclockwise)

Preceding gene: 213692621

Following gene: 213692616

Centisome position: 68.03

GC content: 62.3

Gene sequence:

>618_bases
ATGATTCGAATAGGATTGACCGGTGGTATTGCGGCGGGCAAAAGCACGGTGTCCACAAGACTGCGGGAGCTCGGCGCGGC
GCTTATCGACTATGACGAGCTCGCGCGCCGAGTGGTGGAACCGGGCGGCGTCGGTCTTCGTCGTATAGCGGAATGTTTCG
GCCCCGACGCGCTGACCGATCAGGGGCGGCTCAACCGGCGATGGATCGCCGAGCACGTGTTCGCCGGGCCCGACTCGGAA
CGGATGCGGAGGAAACTGGACGATATCGAGCATCCGTTGATCTATGATCTTGCGCTGTCTCGGGAGCGGCAGGCGGTCGC
GGACAATCCGGATGCCGTGGTCGTGCATGATGTTCCGCTGTTGGCGGAAGTCCTGGACGCCATGCCCATGCGATTCGACC
ATATCGTCACCGTCGAAGCGCCCGAACAAGTGCGGGTCGACAGAATGGTGTCGACCCGCGGCATGACGCGAGATGATGCG
CTTGCGCGCATTCGCCACCAGTCCAGCCCGGAACAACGCCGTGTCATAGCCGACGCGGTGATCGATTCCACGCAGCCGAT
GGGTCGAATGCTCGAAGCCGTCGATGCGCTGTACGAACAGTGGCTGGCGGAATCATAA

Upstream 100 bases:

>100_bases
GACTGACGCCTGACGTATAGTCAAAACCCGGTCTCGCTTCGGCGGGCCGGGTTTTGCCGTTGTGTGCATGAACCTCGAAA
CATGGCCATGATGGGGGAGC

Downstream 100 bases:

>100_bases
TGCGATGATGCGGTCGGCGAGAGCCGCGGTCTCCTCGTTGTGCGTCGTGTAGATCACGATCGCTCCGCTGTCGGCGAAAT
CACGCAGGTGACGCATGACC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MIRIGLTGGIAAGKSTVSTRLRELGAALIDYDELARRVVEPGGVGLRRIAECFGPDALTDQGRLNRRWIAEHVFAGPDSE
RMRRKLDDIEHPLIYDLALSRERQAVADNPDAVVVHDVPLLAEVLDAMPMRFDHIVTVEAPEQVRVDRMVSTRGMTRDDA
LARIRHQSSPEQRRVIADAVIDSTQPMGRMLEAVDALYEQWLAES

Sequences:

>Translated_205_residues
MIRIGLTGGIAAGKSTVSTRLRELGAALIDYDELARRVVEPGGVGLRRIAECFGPDALTDQGRLNRRWIAEHVFAGPDSE
RMRRKLDDIEHPLIYDLALSRERQAVADNPDAVVVHDVPLLAEVLDAMPMRFDHIVTVEAPEQVRVDRMVSTRGMTRDDA
LARIRHQSSPEQRRVIADAVIDSTQPMGRMLEAVDALYEQWLAES
>Mature_205_residues
MIRIGLTGGIAAGKSTVSTRLRELGAALIDYDELARRVVEPGGVGLRRIAECFGPDALTDQGRLNRRWIAEHVFAGPDSE
RMRRKLDDIEHPLIYDLALSRERQAVADNPDAVVVHDVPLLAEVLDAMPMRFDHIVTVEAPEQVRVDRMVSTRGMTRDDA
LARIRHQSSPEQRRVIADAVIDSTQPMGRMLEAVDALYEQWLAES

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=184, Percent_Identity=34.2391304347826, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI191252795, Length=184, Percent_Identity=34.2391304347826, Blast_Score=99, Evalue=3e-21,
Organism=Homo sapiens, GI110227607, Length=170, Percent_Identity=34.7058823529412, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI110227605, Length=170, Percent_Identity=34.7058823529412, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI110227603, Length=170, Percent_Identity=34.7058823529412, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI110227601, Length=170, Percent_Identity=34.7058823529412, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI205277394, Length=170, Percent_Identity=34.7058823529412, Blast_Score=81, Evalue=6e-16,
Organism=Escherichia coli, GI1786292, Length=181, Percent_Identity=33.1491712707182, Blast_Score=91, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI17554944, Length=202, Percent_Identity=31.1881188118812, Blast_Score=90, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6320402, Length=207, Percent_Identity=31.8840579710145, Blast_Score=85, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24644728, Length=185, Percent_Identity=30.8108108108108, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24658602, Length=74, Percent_Identity=47.2972972972973, Blast_Score=70, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22901; Mature: 22901

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRIGLTGGIAAGKSTVSTRLRELGAALIDYDELARRVVEPGGVGLRRIAECFGPDALTD
CEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCC
QGRLNRRWIAEHVFAGPDSERMRRKLDDIEHPLIYDLALSRERQAVADNPDAVVVHDVPL
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECHHH
LAEVLDAMPMRFDHIVTVEAPEQVRVDRMVSTRGMTRDDALARIRHQSSPEQRRVIADAV
HHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHH
IDSTQPMGRMLEAVDALYEQWLAES
HCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIRIGLTGGIAAGKSTVSTRLRELGAALIDYDELARRVVEPGGVGLRRIAECFGPDALTD
CEEECCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHHCCCCCCC
QGRLNRRWIAEHVFAGPDSERMRRKLDDIEHPLIYDLALSRERQAVADNPDAVVVHDVPL
CCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEEEECHHH
LAEVLDAMPMRFDHIVTVEAPEQVRVDRMVSTRGMTRDDALARIRHQSSPEQRRVIADAV
HHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHH
IDSTQPMGRMLEAVDALYEQWLAES
HCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12381787 [H]