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The map label for this gene is uvrB

Identifier: 213692614

GI number: 213692614

Start: 1919182

End: 1921293

Strand: Reverse

Name: uvrB

Synonym: Blon_1747

Alternate gene names: 213692614

Gene position: 1921293-1919182 (Counterclockwise)

Preceding gene: 213692615

Following gene: 213692613

Centisome position: 67.82

GC content: 62.31

Gene sequence:

>2112_bases
ATGGGATTCAACATCGAACGTGTGGACAAGCCGTTTGTGGTCAAATCGCCGTACCAACCATCCGGAGACCAGCCGAAGGC
CATCGAGGAACTGGCCACGCGCATCGAGAACGGAGAGAACGACGTGGTGCTCATGGGCGCCACCGGCACCGGCAAAACCG
CCACCACCGCATGGCTGATCGAACGGCTGCAACGTCCCACGCTCATCATCGAGCCGAACAAGACGCTCGCCGCGCAGCTG
TGCGCCGAATTCCGCGAGCTCATGCCCGACAACGCGGTGAGCTATTTCGTTTCCTACTACGACTACTATCAGCCGGAGGC
CTACATACCGCAGACCGACACCTATATCGAGAAAGACTCCAACATCAACGACGATGTGGAACGTTTGCGCCATCAGGCCA
CGGCCAACCTGCTGACCAGACGCGACTGCGTGGTCGTGGCCACCGTCTCCTGCATCTACGGCCTGGGCACTCCTGAGGAA
TACGCCGGGCGTATGCTGTTTCTCAAGGAAGGCCAGCAGATCAATCGCGACGACCTGCTGCGCCGGTTCGTGGCCATGCA
GTACAAGCGCAACGACATCGCCTTCACCCGCGGCACGTTCCGCGTGCGGGGCGATACGGTCGAAATCATCCCCGTATACG
AGGAACTGGCCATCCGCATCGAATTCTTCGGCGACGAGATCGACCGCATCTCCACCCTGCATCCGCTGACCGGCGATGTG
ATCGCCCATGAACCGCAGGTCCATATCTTCCCGGCCTCCCACTATGTGGCCGGGCCGGAGCGTATGGAACGCGCGCTCAA
AACCATCCGCGAGGAGCTTGACGGACGGTTGTCCGAACTGCGCAAACAGGGCAAGGAACTTGAGGCGCAGCGTCTCGACA
TGCGCACCACCTATGACCTGGAGATGCTCACCCAGGTGGGCGTGTGCTCGGGGGTCGAAAACTATTCGCGTCATCTCGAC
GGCCGCGCGGCCGGCACGCCGCCGCATACGCTGCTCGACTTCTTTCCGGATGATTTCCTGCTGGTCATCGATGAGTCGCA
TGTTACCGTGCCGCAGATCGGCGCGATGTACGAGGGGGACGCCTCCCGCAAGCGCACGTTGGTCGAACACGGGTTCCGCC
TGCCCTCCGCGATGGATAACCGACCGCTCAAATGGCCGGAGTTCCTGCAGCGCGTCGGCCAGACCGTGTATCTGTCCGCC
ACGCCCGGCGACTACGAGTTGGGCTTGTCCGACGGGGTGGTCGAACAGATCATCCGTCCGACCGGCCTGCTGGACCCGAA
GATCGACGTGCGCCCGGTCAAGGGGCAGATCGACGATCTGCTCGCCGAGATCAAGGCCCGTGTGGCCAGGAACGAGCGCG
CGCTGGTCACCACCCTGACCAAGAAGATGGCCGAGGATTTGACCGACTATCTGCTGGAACGCGGGATCAAGGTCGAATAC
CTGCATTCCGATGTGGATACGTTGCGGCGCGTCGAACTGCTGCGCATGTTGCGCGAAGGCAAGATCGATGTGATTGTCGG
TATCAACCTGCTGCGTGAGGGCCTCGATTTGCCGGAAGTATCACTGGTGGCGATCCTCGACGCCGACAAGGAGGGCTTCC
TGCGGTCCTACCGTTCGCTCATCCAGACCATCGGCCGTGCCGCGCGAAACGTGTCCGGCGTGGTGATCATGTACGCCGAC
GAGACCACCGAAGCCATGAGACAGGCGATCGACGAGACCGACCGCCGCCGCGCCAAGCAGATCGCCTACAACCAGGAGCA
TGGCATCGATCCCAAGCCCCTGATCAAGAAGATCAGCGACGTCAACGACATGCTCGCCAAGGAGGATGTGGACACCCAGA
CCTTGCTTGAAGGTGGCTACCGCAACGCGGGCAAGGCCGGCAACACACACCTGGGCGTGCCGGTACTCGATCCCAACGAG
GCGGACAAGCGCCACGAGGAGATCCTGAAGGCCGGCCTGCCCGCGCAGGACCTCGCCGACCTGATTCGCCAGCTGAGCGA
ACAGATGCACACCGCCGCCGAGCAGCTCCAGTTCGAGCTTGCGGCCCGTCTGCGCGACGAGATCCGTGATCTCAAGAAGG
AGCTCCGGCAGATGACCGAGGCGGGGCAATGA

Upstream 100 bases:

>100_bases
TGGTTGGCTGCGCGTCCAAGAGGAAGACGGGTATTGGAGTTGCCTAGCGTATATTCCGATATATCATCGGGATACAGCGT
GAATCGGAAGGAAACAGCGC

Downstream 100 bases:

>100_bases
CCCGTCACATACATGGGTTAGTGTAGGGAATCATGGCAGAAACCCCACTCGCATTTGAAATCATCACCTTCGTGGTGCTC
GCGCTGTTCTTCATCGTCGA

Product: excinuclease ABC subunit B

Products: NA

Alternate protein names: Protein uvrB; Excinuclease ABC subunit B

Number of amino acids: Translated: 703; Mature: 702

Protein sequence:

>703_residues
MGFNIERVDKPFVVKSPYQPSGDQPKAIEELATRIENGENDVVLMGATGTGKTATTAWLIERLQRPTLIIEPNKTLAAQL
CAEFRELMPDNAVSYFVSYYDYYQPEAYIPQTDTYIEKDSNINDDVERLRHQATANLLTRRDCVVVATVSCIYGLGTPEE
YAGRMLFLKEGQQINRDDLLRRFVAMQYKRNDIAFTRGTFRVRGDTVEIIPVYEELAIRIEFFGDEIDRISTLHPLTGDV
IAHEPQVHIFPASHYVAGPERMERALKTIREELDGRLSELRKQGKELEAQRLDMRTTYDLEMLTQVGVCSGVENYSRHLD
GRAAGTPPHTLLDFFPDDFLLVIDESHVTVPQIGAMYEGDASRKRTLVEHGFRLPSAMDNRPLKWPEFLQRVGQTVYLSA
TPGDYELGLSDGVVEQIIRPTGLLDPKIDVRPVKGQIDDLLAEIKARVARNERALVTTLTKKMAEDLTDYLLERGIKVEY
LHSDVDTLRRVELLRMLREGKIDVIVGINLLREGLDLPEVSLVAILDADKEGFLRSYRSLIQTIGRAARNVSGVVIMYAD
ETTEAMRQAIDETDRRRAKQIAYNQEHGIDPKPLIKKISDVNDMLAKEDVDTQTLLEGGYRNAGKAGNTHLGVPVLDPNE
ADKRHEEILKAGLPAQDLADLIRQLSEQMHTAAEQLQFELAARLRDEIRDLKKELRQMTEAGQ

Sequences:

>Translated_703_residues
MGFNIERVDKPFVVKSPYQPSGDQPKAIEELATRIENGENDVVLMGATGTGKTATTAWLIERLQRPTLIIEPNKTLAAQL
CAEFRELMPDNAVSYFVSYYDYYQPEAYIPQTDTYIEKDSNINDDVERLRHQATANLLTRRDCVVVATVSCIYGLGTPEE
YAGRMLFLKEGQQINRDDLLRRFVAMQYKRNDIAFTRGTFRVRGDTVEIIPVYEELAIRIEFFGDEIDRISTLHPLTGDV
IAHEPQVHIFPASHYVAGPERMERALKTIREELDGRLSELRKQGKELEAQRLDMRTTYDLEMLTQVGVCSGVENYSRHLD
GRAAGTPPHTLLDFFPDDFLLVIDESHVTVPQIGAMYEGDASRKRTLVEHGFRLPSAMDNRPLKWPEFLQRVGQTVYLSA
TPGDYELGLSDGVVEQIIRPTGLLDPKIDVRPVKGQIDDLLAEIKARVARNERALVTTLTKKMAEDLTDYLLERGIKVEY
LHSDVDTLRRVELLRMLREGKIDVIVGINLLREGLDLPEVSLVAILDADKEGFLRSYRSLIQTIGRAARNVSGVVIMYAD
ETTEAMRQAIDETDRRRAKQIAYNQEHGIDPKPLIKKISDVNDMLAKEDVDTQTLLEGGYRNAGKAGNTHLGVPVLDPNE
ADKRHEEILKAGLPAQDLADLIRQLSEQMHTAAEQLQFELAARLRDEIRDLKKELRQMTEAGQ
>Mature_702_residues
GFNIERVDKPFVVKSPYQPSGDQPKAIEELATRIENGENDVVLMGATGTGKTATTAWLIERLQRPTLIIEPNKTLAAQLC
AEFRELMPDNAVSYFVSYYDYYQPEAYIPQTDTYIEKDSNINDDVERLRHQATANLLTRRDCVVVATVSCIYGLGTPEEY
AGRMLFLKEGQQINRDDLLRRFVAMQYKRNDIAFTRGTFRVRGDTVEIIPVYEELAIRIEFFGDEIDRISTLHPLTGDVI
AHEPQVHIFPASHYVAGPERMERALKTIREELDGRLSELRKQGKELEAQRLDMRTTYDLEMLTQVGVCSGVENYSRHLDG
RAAGTPPHTLLDFFPDDFLLVIDESHVTVPQIGAMYEGDASRKRTLVEHGFRLPSAMDNRPLKWPEFLQRVGQTVYLSAT
PGDYELGLSDGVVEQIIRPTGLLDPKIDVRPVKGQIDDLLAEIKARVARNERALVTTLTKKMAEDLTDYLLERGIKVEYL
HSDVDTLRRVELLRMLREGKIDVIVGINLLREGLDLPEVSLVAILDADKEGFLRSYRSLIQTIGRAARNVSGVVIMYADE
TTEAMRQAIDETDRRRAKQIAYNQEHGIDPKPLIKKISDVNDMLAKEDVDTQTLLEGGYRNAGKAGNTHLGVPVLDPNEA
DKRHEEILKAGLPAQDLADLIRQLSEQMHTAAEQLQFELAARLRDEIRDLKKELRQMTEAGQ

Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. Upon binding of the uvrA(2)B(2) complex to a putative damaged site, the DNA

COG id: COG0556

COG function: function code L; Helicase subunit of the DNA excision repair complex

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 UVR domain

Homologues:

Organism=Escherichia coli, GI1786996, Length=688, Percent_Identity=53.9244186046512, Blast_Score=718, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UVRB_BIFLI (B7GSZ2)

Other databases:

- EMBL:   CP001095
- RefSeq:   YP_002323200.1
- GeneID:   7054389
- GenomeReviews:   CP001095_GR
- KEGG:   bln:Blon_1747
- HOGENOM:   HBG703949
- ProtClustDB:   PRK05298
- GO:   GO:0005737
- HAMAP:   MF_00204
- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935
- InterPro:   IPR001943
- InterPro:   IPR004807
- InterPro:   IPR009055
- SMART:   SM00487
- SMART:   SM00490
- TIGRFAMs:   TIGR00631

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII; PF02151 UVR; SSF46600 UvrB_C

EC number: NA

Molecular weight: Translated: 79584; Mature: 79453

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS51192 HELICASE_ATP_BIND_1; PS51194 HELICASE_CTER; PS50151 UVR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFNIERVDKPFVVKSPYQPSGDQPKAIEELATRIENGENDVVLMGATGTGKTATTAWLI
CCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHH
ERLQRPTLIIEPNKTLAAQLCAEFRELMPDNAVSYFVSYYDYYQPEAYIPQTDTYIEKDS
HHHCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
NINDDVERLRHQATANLLTRRDCVVVATVSCIYGLGTPEEYAGRMLFLKEGQQINRDDLL
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHCCCEEEEECCCCCCHHHHH
RRFVAMQYKRNDIAFTRGTFRVRGDTVEIIPVYEELAIRIEFFGDEIDRISTLHPLTGDV
HHHHHHHHCCCCEEEECCEEEECCCEEEEEEEHHHHEEEHHHHCCHHHHHHHCCCCCCCC
IAHEPQVHIFPASHYVAGPERMERALKTIREELDGRLSELRKQGKELEAQRLDMRTTYDL
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
EMLTQVGVCSGVENYSRHLDGRAAGTPPHTLLDFFPDDFLLVIDESHVTVPQIGAMYEGD
HHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCEECCC
ASRKRTLVEHGFRLPSAMDNRPLKWPEFLQRVGQTVYLSATPGDYELGLSDGVVEQIIRP
CHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHCC
TGLLDPKIDVRPVKGQIDDLLAEIKARVARNERALVTTLTKKMAEDLTDYLLERGIKVEY
CCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
LHSDVDTLRRVELLRMLREGKIDVIVGINLLREGLDLPEVSLVAILDADKEGFLRSYRSL
ECCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHH
IQTIGRAARNVSGVVIMYADETTEAMRQAIDETDRRRAKQIAYNQEHGIDPKPLIKKISD
HHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
VNDMLAKEDVDTQTLLEGGYRNAGKAGNTHLGVPVLDPNEADKRHEEILKAGLPAQDLAD
HHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCHHHHHH
LIRQLSEQMHTAAEQLQFELAARLRDEIRDLKKELRQMTEAGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GFNIERVDKPFVVKSPYQPSGDQPKAIEELATRIENGENDVVLMGATGTGKTATTAWLI
CCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHH
ERLQRPTLIIEPNKTLAAQLCAEFRELMPDNAVSYFVSYYDYYQPEAYIPQTDTYIEKDS
HHHCCCEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
NINDDVERLRHQATANLLTRRDCVVVATVSCIYGLGTPEEYAGRMLFLKEGQQINRDDLL
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHCCCEEEEECCCCCCHHHHH
RRFVAMQYKRNDIAFTRGTFRVRGDTVEIIPVYEELAIRIEFFGDEIDRISTLHPLTGDV
HHHHHHHHCCCCEEEECCEEEECCCEEEEEEEHHHHEEEHHHHCCHHHHHHHCCCCCCCC
IAHEPQVHIFPASHYVAGPERMERALKTIREELDGRLSELRKQGKELEAQRLDMRTTYDL
CCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
EMLTQVGVCSGVENYSRHLDGRAAGTPPHTLLDFFPDDFLLVIDESHVTVPQIGAMYEGD
HHHHHHHHHCCHHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCEECCC
ASRKRTLVEHGFRLPSAMDNRPLKWPEFLQRVGQTVYLSATPGDYELGLSDGVVEQIIRP
CHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCHHHHHHHHCC
TGLLDPKIDVRPVKGQIDDLLAEIKARVARNERALVTTLTKKMAEDLTDYLLERGIKVEY
CCCCCCCCCCEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEE
LHSDVDTLRRVELLRMLREGKIDVIVGINLLREGLDLPEVSLVAILDADKEGFLRSYRSL
ECCCHHHHHHHHHHHHHHCCCEEEEEEHHHHHCCCCCCCEEEEEEECCCHHHHHHHHHHH
IQTIGRAARNVSGVVIMYADETTEAMRQAIDETDRRRAKQIAYNQEHGIDPKPLIKKISD
HHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
VNDMLAKEDVDTQTLLEGGYRNAGKAGNTHLGVPVLDPNEADKRHEEILKAGLPAQDLAD
HHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHCCCCHHHHHH
LIRQLSEQMHTAAEQLQFELAARLRDEIRDLKKELRQMTEAGQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: Hydrolase; Acting on ester bonds [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA