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The map label for this gene is clpP2 [H]

Identifier: 213692576

GI number: 213692576

Start: 1869974

End: 1870597

Strand: Reverse

Name: clpP2 [H]

Synonym: Blon_1708

Alternate gene names: 213692576

Gene position: 1870597-1869974 (Counterclockwise)

Preceding gene: 213692577

Following gene: 213692575

Centisome position: 66.03

GC content: 62.02

Gene sequence:

>624_bases
GTGAGCAATACCTTTGCGACCTTGCCGGTCATGGCGGGCGATGACGTCCCGGCCGGCCCCGTCGACCCGATTTTCAACCG
TCTGCTCAAAGACCGCATCATCTGGATGGGTGAAGAGGTCAAGGACGATATGGCCAACCGCATCTGCGCTCAGCTGCTGA
TGCTGGCCGCCGAAGACCCGAAGAAGGATATCTGGCTGTACATCAATTCGCCGGGCGGCTCCATCACCGCCGGTATGGCC
ATCTACGACACCATGCAGCTCATCGAGCCGGACGTGGCGACCGTGGGTCTGGGCATGTGCGCCTCCATGGGCCAGTTCCT
GCTGAGCTCCGGCACCAAGGGCAAGCGTTACCTGACCTCGCACGCCCGTGTGCTCATGCACCAGCCCTCCGGCGGCATTG
GCGGCACCGCCACTGACGTGTGCATCAACGCCGAGCTCATCATGGACATGAAGAAGACCATGAGCGAGCTGACCGCCGAA
CAGACCGGCCACACCCTCGAGGAAATCTACCGCGACAACGAATACGACCACTGGTTCACCGCCCAGGAAGCCCTCGACTA
TGGCTTCGTGGACAAGCTCGTGACCACGCCGGACACCATCGGCAACAACCAGCAGGGGGAGTGA

Upstream 100 bases:

>100_bases
ATATCCTACGCTACCCGCCAAAAAGCACGCGAAAAGCCGACTTCAGTCGCTTCAAGGCGGTAGTCTGAACAATGTTCGAG
TAATTAGAAGGAGAATCAAG

Downstream 100 bases:

>100_bases
GACTCATGGCAAGTGAAGAAGCAAAGTTCGCCGCCCGTGCCGACCGCTTGGCCGGCCGTCAGGGCGTAGCCGGTTTCATG
CCGGACGCCGCCCGCGCAGC

Product: Endopeptidase Clp

Products: NA

Alternate protein names: Endopeptidase Clp 2 [H]

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MSNTFATLPVMAGDDVPAGPVDPIFNRLLKDRIIWMGEEVKDDMANRICAQLLMLAAEDPKKDIWLYINSPGGSITAGMA
IYDTMQLIEPDVATVGLGMCASMGQFLLSSGTKGKRYLTSHARVLMHQPSGGIGGTATDVCINAELIMDMKKTMSELTAE
QTGHTLEEIYRDNEYDHWFTAQEALDYGFVDKLVTTPDTIGNNQQGE

Sequences:

>Translated_207_residues
MSNTFATLPVMAGDDVPAGPVDPIFNRLLKDRIIWMGEEVKDDMANRICAQLLMLAAEDPKKDIWLYINSPGGSITAGMA
IYDTMQLIEPDVATVGLGMCASMGQFLLSSGTKGKRYLTSHARVLMHQPSGGIGGTATDVCINAELIMDMKKTMSELTAE
QTGHTLEEIYRDNEYDHWFTAQEALDYGFVDKLVTTPDTIGNNQQGE
>Mature_206_residues
SNTFATLPVMAGDDVPAGPVDPIFNRLLKDRIIWMGEEVKDDMANRICAQLLMLAAEDPKKDIWLYINSPGGSITAGMAI
YDTMQLIEPDVATVGLGMCASMGQFLLSSGTKGKRYLTSHARVLMHQPSGGIGGTATDVCINAELIMDMKKTMSELTAEQ
TGHTLEEIYRDNEYDHWFTAQEALDYGFVDKLVTTPDTIGNNQQGE

Specific function: Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins [H]

COG id: COG0740

COG function: function code OU; Protease subunit of ATP-dependent Clp proteases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S14 family [H]

Homologues:

Organism=Homo sapiens, GI5174419, Length=181, Percent_Identity=43.0939226519337, Blast_Score=159, Evalue=2e-39,
Organism=Escherichia coli, GI1786641, Length=172, Percent_Identity=55.8139534883721, Blast_Score=207, Evalue=5e-55,
Organism=Caenorhabditis elegans, GI17538017, Length=172, Percent_Identity=45.3488372093023, Blast_Score=160, Evalue=3e-40,
Organism=Drosophila melanogaster, GI20129427, Length=174, Percent_Identity=45.4022988505747, Blast_Score=165, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001907 [H]

Pfam domain/function: PF00574 CLP_protease [H]

EC number: =3.4.21.92 [H]

Molecular weight: Translated: 22671; Mature: 22540

Theoretical pI: Translated: 4.27; Mature: 4.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
6.3 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
5.8 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTFATLPVMAGDDVPAGPVDPIFNRLLKDRIIWMGEEVKDDMANRICAQLLMLAAEDP
CCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
KKDIWLYINSPGGSITAGMAIYDTMQLIEPDVATVGLGMCASMGQFLLSSGTKGKRYLTS
CCEEEEEEECCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
HARVLMHQPSGGIGGTATDVCINAELIMDMKKTMSELTAEQTGHTLEEIYRDNEYDHWFT
HHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEC
AQEALDYGFVDKLVTTPDTIGNNQQGE
HHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SNTFATLPVMAGDDVPAGPVDPIFNRLLKDRIIWMGEEVKDDMANRICAQLLMLAAEDP
CCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCC
KKDIWLYINSPGGSITAGMAIYDTMQLIEPDVATVGLGMCASMGQFLLSSGTKGKRYLTS
CCEEEEEEECCCCCEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
HARVLMHQPSGGIGGTATDVCINAELIMDMKKTMSELTAEQTGHTLEEIYRDNEYDHWFT
HHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCEEC
AQEALDYGFVDKLVTTPDTIGNNQQGE
HHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12381787 [H]