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The map label for this gene is csd [H]

Identifier: 213692462

GI number: 213692462

Start: 1742132

End: 1743406

Strand: Reverse

Name: csd [H]

Synonym: Blon_1591

Alternate gene names: 213692462

Gene position: 1743406-1742132 (Counterclockwise)

Preceding gene: 213692463

Following gene: 213692461

Centisome position: 61.54

GC content: 62.35

Gene sequence:

>1275_bases
ATGGTTGATTTTAAGGAGATTCGGGGCGAGTTCCCGATTCTGAATCAGGAGATTCACGGGCACCCGCTCGTGTACCTGGA
TTCTGCGGCCACCTCGCAGAAGCCGAATGCGGTGATCGACGCCGAGGCGAACTTCTACCGTACGATCAACGCCGGCGTGC
ACCGCGGTGCCCACGAGCTGGCGGCCCGTAGTACCATGGCTTTCGAAGAGGCCCGTGCCAAGGTCGCCAAGCTGGTCGGC
GCGAATGCAGCGGAAGGCGAAGAAGAGATCGTCGTCACCGGTGGTGCCACGGCCGGACTGAACCTGCTCGCCACCGCGTT
CGGCAATGCGTCGCTGGGCCGTGGGGGAGAAGCCGCCAAGCGTTTTGCCCTGAAGCCGGGCGATGAGATCGTCGTCTCGC
GCGCGGAACATCATTCGGTGCTGCTGCCGTTCCAGGAGCTGGCCTACCGTACCGGTGCCACCTTCAAGTGGATCGACCTG
ACCGAGGACGGCCGTGTGCGTACGGACAACCTCGACGAAGTCATCACCGAGCGTACCAAGGTCGTGGCTGTCACCCACGT
GGGCAACACCACGGGTGCCATCACCAACATCGCCCCTATCATCAAGCGTGCGCATGAAGTAGGTTCGATCTTCATCTTGG
ACGCTTGCCAGTCCGTACCGCACCTCAAAGTCGATTTCCATGCGCTTGATGTGGACTTCGCTGCCTGGAGCGCGCACAAG
ATGTACGGTCCTACCGGCGTCGGTTTCCTGTACGGTAAGCGCGAACTGCTCGAAGCCCTGCCGCCGGCCAACTTCGGCGG
CTCCATGGTCGAGCTCGCCTACATGGACCACGAGGCCCAATACATGGCCCCTCCGGCCCGTTTCGAGGCCGGCACCCAGC
CGGTCGCCCAAGTGGTGGCCGCAGGCGTCGCCGCCGAATGGATGATGAATATCGGTCTTGAGAACATCGAAGCCCATGAG
AAGACCATCGCCGCCGAACTGCTGAAGCTCGGCGACATCGATGGCATTCGTATCCTCGGACCGCGCGAAAACGTGGACCG
CATCGGCACCGTGGCGTTCGACGTGGCCGGCGTGCACCCGCACGATGTGGGCCAGTTCATCGACGCCCAGGGCATCGCGA
TTCGCGTGGGGCACCACTGCGCCCAGCCGGTACACCGCCACTTCGGCCTATACGCATCCAACCGTGCCTCCTCCGGTGTC
TACAATTCGGTCGAAGATGCCCAAGCATTGGTCGAAGCGGCCAAGGGTATCCGTAAGTTCTTTGGAGTGGAGTAA

Upstream 100 bases:

>100_bases
ACACGTTCCGGGCCGCTCAGGCCAAGTCTTTACGGTCGCGAACAGGCCATGTCCGACTCCCACTCGTTTCGTACAATTGT
TACGTAAGTAGGGGAACATA

Downstream 100 bases:

>100_bases
AACAGATCACCATGAACGAATTCGGTATGAGCGGGGATGACCTCGAACAGATGTACCAAGAGGTCATCCTCGAGGCGTCA
AAACATCCGCATGGCAAGGA

Product: cysteine desulfurase, SufS subfamily

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MVDFKEIRGEFPILNQEIHGHPLVYLDSAATSQKPNAVIDAEANFYRTINAGVHRGAHELAARSTMAFEEARAKVAKLVG
ANAAEGEEEIVVTGGATAGLNLLATAFGNASLGRGGEAAKRFALKPGDEIVVSRAEHHSVLLPFQELAYRTGATFKWIDL
TEDGRVRTDNLDEVITERTKVVAVTHVGNTTGAITNIAPIIKRAHEVGSIFILDACQSVPHLKVDFHALDVDFAAWSAHK
MYGPTGVGFLYGKRELLEALPPANFGGSMVELAYMDHEAQYMAPPARFEAGTQPVAQVVAAGVAAEWMMNIGLENIEAHE
KTIAAELLKLGDIDGIRILGPRENVDRIGTVAFDVAGVHPHDVGQFIDAQGIAIRVGHHCAQPVHRHFGLYASNRASSGV
YNSVEDAQALVEAAKGIRKFFGVE

Sequences:

>Translated_424_residues
MVDFKEIRGEFPILNQEIHGHPLVYLDSAATSQKPNAVIDAEANFYRTINAGVHRGAHELAARSTMAFEEARAKVAKLVG
ANAAEGEEEIVVTGGATAGLNLLATAFGNASLGRGGEAAKRFALKPGDEIVVSRAEHHSVLLPFQELAYRTGATFKWIDL
TEDGRVRTDNLDEVITERTKVVAVTHVGNTTGAITNIAPIIKRAHEVGSIFILDACQSVPHLKVDFHALDVDFAAWSAHK
MYGPTGVGFLYGKRELLEALPPANFGGSMVELAYMDHEAQYMAPPARFEAGTQPVAQVVAAGVAAEWMMNIGLENIEAHE
KTIAAELLKLGDIDGIRILGPRENVDRIGTVAFDVAGVHPHDVGQFIDAQGIAIRVGHHCAQPVHRHFGLYASNRASSGV
YNSVEDAQALVEAAKGIRKFFGVE
>Mature_424_residues
MVDFKEIRGEFPILNQEIHGHPLVYLDSAATSQKPNAVIDAEANFYRTINAGVHRGAHELAARSTMAFEEARAKVAKLVG
ANAAEGEEEIVVTGGATAGLNLLATAFGNASLGRGGEAAKRFALKPGDEIVVSRAEHHSVLLPFQELAYRTGATFKWIDL
TEDGRVRTDNLDEVITERTKVVAVTHVGNTTGAITNIAPIIKRAHEVGSIFILDACQSVPHLKVDFHALDVDFAAWSAHK
MYGPTGVGFLYGKRELLEALPPANFGGSMVELAYMDHEAQYMAPPARFEAGTQPVAQVVAAGVAAEWMMNIGLENIEAHE
KTIAAELLKLGDIDGIRILGPRENVDRIGTVAFDVAGVHPHDVGQFIDAQGIAIRVGHHCAQPVHRHFGLYASNRASSGV
YNSVEDAQALVEAAKGIRKFFGVE

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=231, Percent_Identity=27.7056277056277, Blast_Score=85, Evalue=1e-16,
Organism=Escherichia coli, GI1787970, Length=418, Percent_Identity=38.755980861244, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1789175, Length=410, Percent_Identity=37.5609756097561, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI48994898, Length=284, Percent_Identity=30.2816901408451, Blast_Score=103, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25143064, Length=231, Percent_Identity=25.974025974026, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI193211090, Length=354, Percent_Identity=24.0112994350282, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319831, Length=308, Percent_Identity=27.2727272727273, Blast_Score=104, Evalue=3e-23,
Organism=Drosophila melanogaster, GI20129463, Length=265, Percent_Identity=29.4339622641509, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45576; Mature: 45576

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDFKEIRGEFPILNQEIHGHPLVYLDSAATSQKPNAVIDAEANFYRTINAGVHRGAHEL
CCCHHHHCCCCCEECCCCCCCCEEEEECCCCCCCCCEEEECCCCEEEEEHHHHHCCHHHH
AARSTMAFEEARAKVAKLVGANAAEGEEEIVVTGGATAGLNLLATAFGNASLGRGGEAAK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHH
RFALKPGDEIVVSRAEHHSVLLPFQELAYRTGATFKWIDLTEDGRVRTDNLDEVITERTK
HHCCCCCCCEEEEECCCCEEEECHHHHHHHCCCEEEEEEECCCCCEECCCHHHHHHCCEE
VVAVTHVGNTTGAITNIAPIIKRAHEVGSIFILDACQSVPHLKVDFHALDVDFAAWSAHK
EEEEEECCCCCCHHHHHHHHHHHHHHHCCEEEEEHHCCCCCEEEEEEEEEEEHHHHCCCC
MYGPTGVGFLYGKRELLEALPPANFGGSMVELAYMDHEAQYMAPPARFEAGTQPVAQVVA
CCCCCCCCHHHCHHHHHHHCCCCCCCCCEEEEEEECCCHHHCCCCHHHCCCCHHHHHHHH
AGVAAEWMMNIGLENIEAHEKTIAAELLKLGDIDGIRILGPRENVDRIGTVAFDVAGVHP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHCEEEEEECCCCH
HDVGQFIDAQGIAIRVGHHCAQPVHRHFGLYASNRASSGVYNSVEDAQALVEAAKGIRKF
HHHHHHHCCCCEEEEECHHHHHHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
FGVE
HCCC
>Mature Secondary Structure
MVDFKEIRGEFPILNQEIHGHPLVYLDSAATSQKPNAVIDAEANFYRTINAGVHRGAHEL
CCCHHHHCCCCCEECCCCCCCCEEEEECCCCCCCCCEEEECCCCEEEEEHHHHHCCHHHH
AARSTMAFEEARAKVAKLVGANAAEGEEEIVVTGGATAGLNLLATAFGNASLGRGGEAAK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHH
RFALKPGDEIVVSRAEHHSVLLPFQELAYRTGATFKWIDLTEDGRVRTDNLDEVITERTK
HHCCCCCCCEEEEECCCCEEEECHHHHHHHCCCEEEEEEECCCCCEECCCHHHHHHCCEE
VVAVTHVGNTTGAITNIAPIIKRAHEVGSIFILDACQSVPHLKVDFHALDVDFAAWSAHK
EEEEEECCCCCCHHHHHHHHHHHHHHHCCEEEEEHHCCCCCEEEEEEEEEEEHHHHCCCC
MYGPTGVGFLYGKRELLEALPPANFGGSMVELAYMDHEAQYMAPPARFEAGTQPVAQVVA
CCCCCCCCHHHCHHHHHHHCCCCCCCCCEEEEEEECCCHHHCCCCHHHCCCCHHHHHHHH
AGVAAEWMMNIGLENIEAHEKTIAAELLKLGDIDGIRILGPRENVDRIGTVAFDVAGVHP
HHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHCEEEEEECCCCH
HDVGQFIDAQGIAIRVGHHCAQPVHRHFGLYASNRASSGVYNSVEDAQALVEAAKGIRKF
HHHHHHHCCCCEEEEECHHHHHHHHHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHH
FGVE
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]