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The map label for this gene is truD [H]

Identifier: 213692266

GI number: 213692266

Start: 1554081

End: 1555118

Strand: Direct

Name: truD [H]

Synonym: Blon_1387

Alternate gene names: 213692266

Gene position: 1554081-1555118 (Clockwise)

Preceding gene: 213692265

Following gene: 213692267

Centisome position: 54.86

GC content: 40.94

Gene sequence:

>1038_bases
ATGTCAAGTTTCTTCGCACTCTCTTCTTCGCAGATAACCTATTGCGGTCTAAAAGACGAAGAGGGAATTACCACCCAAGA
GGTGTCCATCAAAGTCCATATTCCTGATGAAGCTTTAGAGCGATTCAATGCAACGATGTATGCCAGTTCAGCATATATTG
AACTAACTTATATTGGACAATCAAATTCACAGGAAATAGGAAAATTGCTCGGGAACGCATTCACTGTCACATTACGAAAT
TTAAGTGGTGACGATGCAGAGGCCTTTTCAGAAATTCATAAAAGAGACTATGCATTCCTGAATTATTATGACTATCAACG
TTTTGGCATTCCCGGATACCCTCAAGTCACGCATCTTTTAGGGAAGGCTTTACTGGATCAAGACTATCAGCGCGCATTCA
AGTTATATAGACTTAGCGGAAACACAAAAATTGATTCAGTAAAGGACCCGGAGAAGTTCTTCACAAGTGACGTTGATGCT
CGAAAGTTATCATTTTTCAAAAATGCCTATTCTTCAAGCATTTGGAACAACGAACTCATGTACCTTGTACAACGCAACGT
ACCGAACACCGTAATTGATGATTCAACGGGAATAACCTACAGATTCTGCAAAAATCTGAAAGATGTACTTTTGCTCTTGC
GACAGGGGGATAATTTACCGTATCTGAAATATGACGTGCAAGGTTCTCATCAATCCGAAAGGTCTCTCATAACTCATACG
AGGGTTGAATGTCTAAATACATCTGACGACGAAAGGCACGCTAACTGCAAAAACGCAACAGTTACCTTCATTTTGCCGTC
TGGCTGCTACGCAACAACTTTTATACGTCAGCTTTGCACATGTCTCATGCATCAAGGAACGTACCCCTTCGTCTGCTGCA
CACGGAAGCTACCAGATGAACTCACAAACTGCAACCTATCCTGTAGTTTCCATTCAATCCAAGCTATCAACGGTAGTATT
ATTGCAATAGTTCCCTCATGGATAAAAGGCAAATGTTTTCGCTTACCAGAAAGTCTCTTAGTCTTAGGTTTTGTGTGA

Upstream 100 bases:

>100_bases
ATAGTACATGAAATCTCAATTCCGACTTCCGACGGAGTATACACTCATTCAAGATATCGTCTAGCAAAAAGGATATAGCC
CATTTGAAGCAATCGAGTGC

Downstream 100 bases:

>100_bases
TGATTGGCGTGTGTGTACGCCGGGGTATGGCATCACGCTTGACCGGTTCATGAGGGTCGCGCACCTGTTGCCGCGACAGA
GGGGCAACGTGGCGGTCGAC

Product: hypothetical protein

Products: NA

Alternate protein names: tRNA pseudouridylate synthase D; tRNA-uridine isomerase D [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MSSFFALSSSQITYCGLKDEEGITTQEVSIKVHIPDEALERFNATMYASSAYIELTYIGQSNSQEIGKLLGNAFTVTLRN
LSGDDAEAFSEIHKRDYAFLNYYDYQRFGIPGYPQVTHLLGKALLDQDYQRAFKLYRLSGNTKIDSVKDPEKFFTSDVDA
RKLSFFKNAYSSSIWNNELMYLVQRNVPNTVIDDSTGITYRFCKNLKDVLLLLRQGDNLPYLKYDVQGSHQSERSLITHT
RVECLNTSDDERHANCKNATVTFILPSGCYATTFIRQLCTCLMHQGTYPFVCCTRKLPDELTNCNLSCSFHSIQAINGSI
IAIVPSWIKGKCFRLPESLLVLGFV

Sequences:

>Translated_345_residues
MSSFFALSSSQITYCGLKDEEGITTQEVSIKVHIPDEALERFNATMYASSAYIELTYIGQSNSQEIGKLLGNAFTVTLRN
LSGDDAEAFSEIHKRDYAFLNYYDYQRFGIPGYPQVTHLLGKALLDQDYQRAFKLYRLSGNTKIDSVKDPEKFFTSDVDA
RKLSFFKNAYSSSIWNNELMYLVQRNVPNTVIDDSTGITYRFCKNLKDVLLLLRQGDNLPYLKYDVQGSHQSERSLITHT
RVECLNTSDDERHANCKNATVTFILPSGCYATTFIRQLCTCLMHQGTYPFVCCTRKLPDELTNCNLSCSFHSIQAINGSI
IAIVPSWIKGKCFRLPESLLVLGFV
>Mature_344_residues
SSFFALSSSQITYCGLKDEEGITTQEVSIKVHIPDEALERFNATMYASSAYIELTYIGQSNSQEIGKLLGNAFTVTLRNL
SGDDAEAFSEIHKRDYAFLNYYDYQRFGIPGYPQVTHLLGKALLDQDYQRAFKLYRLSGNTKIDSVKDPEKFFTSDVDAR
KLSFFKNAYSSSIWNNELMYLVQRNVPNTVIDDSTGITYRFCKNLKDVLLLLRQGDNLPYLKYDVQGSHQSERSLITHTR
VECLNTSDDERHANCKNATVTFILPSGCYATTFIRQLCTCLMHQGTYPFVCCTRKLPDELTNCNLSCSFHSIQAINGSII
AIVPSWIKGKCFRLPESLLVLGFV

Specific function: Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs [H]

COG id: COG0585

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRUD domain [H]

Homologues:

Organism=Homo sapiens, GI50727002, Length=136, Percent_Identity=30.1470588235294, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI21355799, Length=142, Percent_Identity=30.9859154929577, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR001656
- InterPro:   IPR020119
- InterPro:   IPR011760 [H]

Pfam domain/function: PF01142 TruD [H]

EC number: NA

Molecular weight: Translated: 39110; Mature: 38979

Theoretical pI: Translated: 6.90; Mature: 6.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSFFALSSSQITYCGLKDEEGITTQEVSIKVHIPDEALERFNATMYASSAYIELTYIGQ
CCCCEEECCCCEEEECCCCCCCCEEEEEEEEEECCHHHHHHHCCEEEECCEEEEEEEECC
SNSQEIGKLLGNAFTVTLRNLSGDDAEAFSEIHKRDYAFLNYYDYQRFGIPGYPQVTHLL
CCHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCEECCCCCCHHHHHHH
GKALLDQDYQRAFKLYRLSGNTKIDSVKDPEKFFTSDVDARKLSFFKNAYSSSIWNNELM
HHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCEE
YLVQRNVPNTVIDDSTGITYRFCKNLKDVLLLLRQGDNLPYLKYDVQGSHQSERSLITHT
EEEECCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHH
RVECLNTSDDERHANCKNATVTFILPSGCYATTFIRQLCTCLMHQGTYPFVCCTRKLPDE
HHEEECCCCCHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCHH
LTNCNLSCSFHSIQAINGSIIAIVPSWIKGKCFRLPESLLVLGFV
HHCCCEEEEEEEEEECCCEEEEEECCCCCCCHHCCCHHHEEEECC
>Mature Secondary Structure 
SSFFALSSSQITYCGLKDEEGITTQEVSIKVHIPDEALERFNATMYASSAYIELTYIGQ
CCCEEECCCCEEEECCCCCCCCEEEEEEEEEECCHHHHHHHCCEEEECCEEEEEEEECC
SNSQEIGKLLGNAFTVTLRNLSGDDAEAFSEIHKRDYAFLNYYDYQRFGIPGYPQVTHLL
CCHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEEECCEECCCCCCHHHHHHH
GKALLDQDYQRAFKLYRLSGNTKIDSVKDPEKFFTSDVDARKLSFFKNAYSSSIWNNELM
HHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCCCCCEE
YLVQRNVPNTVIDDSTGITYRFCKNLKDVLLLLRQGDNLPYLKYDVQGSHQSERSLITHT
EEEECCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCHHHHHHHH
RVECLNTSDDERHANCKNATVTFILPSGCYATTFIRQLCTCLMHQGTYPFVCCTRKLPDE
HHEEECCCCCHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCHH
LTNCNLSCSFHSIQAINGSIIAIVPSWIKGKCFRLPESLLVLGFV
HHCCCEEEEEEEEEECCCEEEEEECCCCCCCHHCCCHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]