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The map label for this gene is aqpZ [H]

Identifier: 213692047

GI number: 213692047

Start: 1347384

End: 1348352

Strand: Reverse

Name: aqpZ [H]

Synonym: Blon_1165

Alternate gene names: 213692047

Gene position: 1348352-1347384 (Counterclockwise)

Preceding gene: 213692050

Following gene: 213692034

Centisome position: 47.6

GC content: 58.31

Gene sequence:

>969_bases
ATGGAAGAAACCAAGCAACAGCCGCTGGCTCTGCGCGTGTGCGCCGAATCGGCCGGCAGCTTCCTGCTGTGCTTTGCGAT
TTACGCCTTCTCCACATGGGGTTCGGCCGTATATGGCATCAATATCGTGTTCTTCGCGTTGGCTACCGGCTTGGCATATG
CCGCAGTCACCGCCATCTTCTCCCGCGTGTCCGGTGGTCAGCTGAATCCGGCCATCACCGTAGCCTCCGTGCTGGTTTCC
AAGACGAAAATCCTGGATGGCATCCTCTATGTGATCGCTCAGGTCATCGGTGCCATCGCCGCCGGCTTCGCCGTGGTCAA
GCTGCTGCCCACATCCGAGCAGGTAGCTGCCAAAGTGTGGCTGACTCCGGCCGTTAACGGTTTCGAAAACGGCTCCGTGT
CTTACTCGCTGCTGACCCAGTATGGCATTACGTTCTCGATTACGTTGGCGATTGTCGTCGAGGTCGTTGCCTCTCTGATT
GTCGTTGCCACCGCCATGTCTTCTCTGGGTGATCACGGCGAGTCCTCGGACCGTCATATCATTGCCTTGGGTCTTGCCTA
TGGTCTGGCCGCCGCCATCAGCTACCCGGTTACCGGTGCCGGTCTCAATCCCGCCCGTTCCACCGGTATCGCACTGGCCG
CGATGAATGAGGGCCTTACGCAAAATCCGCTGCAGCAGCTGTGGGTATTCTGGATTAGCCCGGTCTTGGCCGCCTCTGTG
GTGGCGTTGGTCATGATCATCGCTCAGATGATGACCACTCCCAAAGTGCCGGCTGCCGCCGATCTTCCACAGACGGATGC
CGATGCGAACGCGGACACACTCGACGATGGCGAATTCTTCGATCAGGCCGCCTCGTCTGATGGCGATTCAGCGGAAAAAG
ATGTTGCCGAAGAGTCCAAAGAAGCTGAAGTAGGTAATCAGCAGGCCGATTCCCAAGGCGATGCCGATGAAGGAGTCGAA
CGCCACTGA

Upstream 100 bases:

>100_bases
CCAACCCATATATCATACCGCAACGTAGGACTGCTGCTAGACTGGCAACCGTTTGTGCGGGTTCGCCCGTCTTCCAACAG
ATGAAAAGGAATGAACAATC

Downstream 100 bases:

>100_bases
GCGCACTTTCCATGGGCTTTTGTCCTGAAGAATCAGGCGAACAAGCCCGGTGATGATGGCCGTCACGGCAAGTATGACCG
TGGCGGCCATCGTATATCCA

Product: major intrinsic protein

Products: H2O [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MEETKQQPLALRVCAESAGSFLLCFAIYAFSTWGSAVYGINIVFFALATGLAYAAVTAIFSRVSGGQLNPAITVASVLVS
KTKILDGILYVIAQVIGAIAAGFAVVKLLPTSEQVAAKVWLTPAVNGFENGSVSYSLLTQYGITFSITLAIVVEVVASLI
VVATAMSSLGDHGESSDRHIIALGLAYGLAAAISYPVTGAGLNPARSTGIALAAMNEGLTQNPLQQLWVFWISPVLAASV
VALVMIIAQMMTTPKVPAAADLPQTDADANADTLDDGEFFDQAASSDGDSAEKDVAEESKEAEVGNQQADSQGDADEGVE
RH

Sequences:

>Translated_322_residues
MEETKQQPLALRVCAESAGSFLLCFAIYAFSTWGSAVYGINIVFFALATGLAYAAVTAIFSRVSGGQLNPAITVASVLVS
KTKILDGILYVIAQVIGAIAAGFAVVKLLPTSEQVAAKVWLTPAVNGFENGSVSYSLLTQYGITFSITLAIVVEVVASLI
VVATAMSSLGDHGESSDRHIIALGLAYGLAAAISYPVTGAGLNPARSTGIALAAMNEGLTQNPLQQLWVFWISPVLAASV
VALVMIIAQMMTTPKVPAAADLPQTDADANADTLDDGEFFDQAASSDGDSAEKDVAEESKEAEVGNQQADSQGDADEGVE
RH
>Mature_322_residues
MEETKQQPLALRVCAESAGSFLLCFAIYAFSTWGSAVYGINIVFFALATGLAYAAVTAIFSRVSGGQLNPAITVASVLVS
KTKILDGILYVIAQVIGAIAAGFAVVKLLPTSEQVAAKVWLTPAVNGFENGSVSYSLLTQYGITFSITLAIVVEVVASLI
VVATAMSSLGDHGESSDRHIIALGLAYGLAAAISYPVTGAGLNPARSTGIALAAMNEGLTQNPLQQLWVFWISPVLAASV
VALVMIIAQMMTTPKVPAAADLPQTDADANADTLDDGEFFDQAASSDGDSAEKDVAEESKEAEVGNQQADSQGDADEGVE
RH

Specific function: Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response

COG id: COG0580

COG function: function code G; Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MIP/aquaporin (TC 1.A.8) family [H]

Homologues:

Organism=Homo sapiens, GI4502181, Length=199, Percent_Identity=30.1507537688442, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI4755125, Length=199, Percent_Identity=30.1507537688442, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI37694062, Length=210, Percent_Identity=29.0476190476191, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1787101, Length=231, Percent_Identity=33.3333333333333, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24652751, Length=228, Percent_Identity=28.9473684210526, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19922038, Length=228, Percent_Identity=28.9473684210526, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24652747, Length=234, Percent_Identity=26.0683760683761, Blast_Score=65, Evalue=6e-11,
Organism=Drosophila melanogaster, GI45551084, Length=234, Percent_Identity=26.0683760683761, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012269
- InterPro:   IPR000425
- InterPro:   IPR022357 [H]

Pfam domain/function: PF00230 MIP [H]

EC number: NA

Molecular weight: Translated: 33379; Mature: 33379

Theoretical pI: Translated: 4.01; Mature: 4.01

Prosite motif: PS00221 MIP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEETKQQPLALRVCAESAGSFLLCFAIYAFSTWGSAVYGINIVFFALATGLAYAAVTAIF
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
SRVSGGQLNPAITVASVLVSKTKILDGILYVIAQVIGAIAAGFAVVKLLPTSEQVAAKVW
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHE
LTPAVNGFENGSVSYSLLTQYGITFSITLAIVVEVVASLIVVATAMSSLGDHGESSDRHI
ECCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
IALGLAYGLAAAISYPVTGAGLNPARSTGIALAAMNEGLTQNPLQQLWVFWISPVLAASV
EEHHHHHHHHHHHHCCCCCCCCCCHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
VALVMIIAQMMTTPKVPAAADLPQTDADANADTLDDGEFFDQAASSDGDSAEKDVAEESK
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHH
EAEVGNQQADSQGDADEGVERH
HHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEETKQQPLALRVCAESAGSFLLCFAIYAFSTWGSAVYGINIVFFALATGLAYAAVTAIF
CCCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHH
SRVSGGQLNPAITVASVLVSKTKILDGILYVIAQVIGAIAAGFAVVKLLPTSEQVAAKVW
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHE
LTPAVNGFENGSVSYSLLTQYGITFSITLAIVVEVVASLIVVATAMSSLGDHGESSDRHI
ECCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEE
IALGLAYGLAAAISYPVTGAGLNPARSTGIALAAMNEGLTQNPLQQLWVFWISPVLAASV
EEHHHHHHHHHHHHCCCCCCCCCCHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHH
VALVMIIAQMMTTPKVPAAADLPQTDADANADTLDDGEFFDQAASSDGDSAEKDVAEESK
HHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHH
EAEVGNQQADSQGDADEGVERH
HHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: H2O [Periplasm] [C]

Specific reaction: H2O [Periplasm] = H2O [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]