Click here to switch to the map view.

The map label for this gene is mepA [H]

Identifier: 213691975

GI number: 213691975

Start: 1279424

End: 1280782

Strand: Direct

Name: mepA [H]

Synonym: Blon_1093

Alternate gene names: 213691975

Gene position: 1279424-1280782 (Clockwise)

Preceding gene: 213691974

Following gene: 213691979

Centisome position: 45.17

GC content: 61.44

Gene sequence:

>1359_bases
ATGGCGCATACAGACGCACTTGATTCAGGGCTGGGCGTCACGCCGGTGCCCCGTCTGGCCCTCACCATGTCGTTCCCCGC
CATCGTGGCGCAGGCGGCGAACGCCTCGTACACGATCATCGACCGGATGTTCATAGGGCATATCCCCGAAGTCGGCAATG
CGGCGATGACGGGAGTCGGCATCTGTTTCCCGATTCTGTTGGCCGTCACCGCCTTCGCCTCGCTGATCGGCGCCGGCGGC
GCGCCGCGCGCCTCCATTGAACTCGGTCGCGGCAACTTCAAGAAGGCCGAGCGTATCCTCGGTACCAGCACGGCGTTCCT
CGTCGTCATAGCCCTGACCCTCACCGCGGTGCTGCAGTCGGTGAAACGGCCGATTCTCTATGCCTTCGGCGCTAGCGACG
CGACCATCGCCTATGCGACCGATTTCATCACCATCTACCTGATCGGCACCGTTTTCGTGCAGTTGACGCTCGGGCTGAAC
AGCTTCATCTCGGCGCAGGGCAAGACCACGGTGGCCATGGTCTCGGTGCTCATCGGCACCGGTGCGTCCATGGTTCTCGA
TCCCGTGTTCATTTTCGTTTTCGGATGGGGCGTCAGGGGAGCGGCCGCCGCGAATGTGATCGCACAACTGATTTCGACGG
TATGGATCGTGCTGTTCCTTTCCTCGGGGCGCAGCGCCATTCGTCTGCGCCCGGCGAACATCCGAATCGACCGAATCATC
ATTCCCGTGTTGACGCTTGGTCTGGCGCCCTTCATCATGCAGATTACGGAATGTCTGATCAATGTGGTGTTCAATGTCGG
TCTGCAGCGGTACGGCGGTGATGATTACGTCACCTCGATCACCATCATCACGTCGCTGATACAGGTCGTGGGCGTACTGA
CCGGCGGTTTTCAGCAGGGCATCCAGCCGATCATAGGGTTCAATTTCGGCGCCCGCAATATGCGGCGCGTCCGGCAGGCG
ATTCGCATGGCCTTCGTCACGCAGATCGCCTCCGCCACGGCGTTGGTGTCGGTGCTTGCCGCATTCCCGGGATTCTTCGC
ATCATGGTTCACCACGGAACAGACGGTCATCGACATCGTGACCCGCATGATGCCGATCTTCGTATGCGGCTGGGGCGTCT
TCGGCATCCAGCTGGGCGCGCAATGCGCATTCGTCGGCATGGGGCAGGCCGGACAGTCGGTGTTCCTGGCCGTCTTCCGC
AAGGTCATCCTGCTTGTACCGCTCGCATTGCTACTGCCGCATTGGCTCGGCGTCGATGGCATCTTCATCGCCGAACCCAT
CTCCGACGCCACCTCGGGCATGGTGGCCGGTCTGCTGTTCCTCATCACCTACCGCAGGATCCGACGGAATCTGGTCTAG

Upstream 100 bases:

>100_bases
CGACCACTTCCGTGTGGTGTACCTGCCGCGCATAGGCATGCTGCACGAAACCATGGAGGAGCTCGCCGACTTCTTCAGCT
ACTACCGGCAGAACTGACCC

Downstream 100 bases:

>100_bases
ATGTCGCGGCCGGCAGGCGTGACGCGCCGCTTGTCGACGATGCCGGCAATGACGCCGATGACGGCGGGTAGGATCCAGCC
GAGCTGGTACTGCTGCAAGG

Product: MATE efflux family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 451

Protein sequence:

>452_residues
MAHTDALDSGLGVTPVPRLALTMSFPAIVAQAANASYTIIDRMFIGHIPEVGNAAMTGVGICFPILLAVTAFASLIGAGG
APRASIELGRGNFKKAERILGTSTAFLVVIALTLTAVLQSVKRPILYAFGASDATIAYATDFITIYLIGTVFVQLTLGLN
SFISAQGKTTVAMVSVLIGTGASMVLDPVFIFVFGWGVRGAAAANVIAQLISTVWIVLFLSSGRSAIRLRPANIRIDRII
IPVLTLGLAPFIMQITECLINVVFNVGLQRYGGDDYVTSITIITSLIQVVGVLTGGFQQGIQPIIGFNFGARNMRRVRQA
IRMAFVTQIASATALVSVLAAFPGFFASWFTTEQTVIDIVTRMMPIFVCGWGVFGIQLGAQCAFVGMGQAGQSVFLAVFR
KVILLVPLALLLPHWLGVDGIFIAEPISDATSGMVAGLLFLITYRRIRRNLV

Sequences:

>Translated_452_residues
MAHTDALDSGLGVTPVPRLALTMSFPAIVAQAANASYTIIDRMFIGHIPEVGNAAMTGVGICFPILLAVTAFASLIGAGG
APRASIELGRGNFKKAERILGTSTAFLVVIALTLTAVLQSVKRPILYAFGASDATIAYATDFITIYLIGTVFVQLTLGLN
SFISAQGKTTVAMVSVLIGTGASMVLDPVFIFVFGWGVRGAAAANVIAQLISTVWIVLFLSSGRSAIRLRPANIRIDRII
IPVLTLGLAPFIMQITECLINVVFNVGLQRYGGDDYVTSITIITSLIQVVGVLTGGFQQGIQPIIGFNFGARNMRRVRQA
IRMAFVTQIASATALVSVLAAFPGFFASWFTTEQTVIDIVTRMMPIFVCGWGVFGIQLGAQCAFVGMGQAGQSVFLAVFR
KVILLVPLALLLPHWLGVDGIFIAEPISDATSGMVAGLLFLITYRRIRRNLV
>Mature_451_residues
AHTDALDSGLGVTPVPRLALTMSFPAIVAQAANASYTIIDRMFIGHIPEVGNAAMTGVGICFPILLAVTAFASLIGAGGA
PRASIELGRGNFKKAERILGTSTAFLVVIALTLTAVLQSVKRPILYAFGASDATIAYATDFITIYLIGTVFVQLTLGLNS
FISAQGKTTVAMVSVLIGTGASMVLDPVFIFVFGWGVRGAAAANVIAQLISTVWIVLFLSSGRSAIRLRPANIRIDRIII
PVLTLGLAPFIMQITECLINVVFNVGLQRYGGDDYVTSITIITSLIQVVGVLTGGFQQGIQPIIGFNFGARNMRRVRQAI
RMAFVTQIASATALVSVLAAFPGFFASWFTTEQTVIDIVTRMMPIFVCGWGVFGIQLGAQCAFVGMGQAGQSVFLAVFRK
VILLVPLALLLPHWLGVDGIFIAEPISDATSGMVAGLLFLITYRRIRRNLV

Specific function: Multidrug resistance efflux protein [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48069; Mature: 47938

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHTDALDSGLGVTPVPRLALTMSFPAIVAQAANASYTIIDRMFIGHIPEVGNAAMTGVG
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHH
ICFPILLAVTAFASLIGAGGAPRASIELGRGNFKKAERILGTSTAFLVVIALTLTAVLQS
HHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VKRPILYAFGASDATIAYATDFITIYLIGTVFVQLTLGLNSFISAQGKTTVAMVSVLIGT
HCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
GASMVLDPVFIFVFGWGVRGAAAANVIAQLISTVWIVLFLSSGRSAIRLRPANIRIDRII
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEHHHH
IPVLTLGLAPFIMQITECLINVVFNVGLQRYGGDDYVTSITIITSLIQVVGVLTGGFQQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHC
IQPIIGFNFGARNMRRVRQAIRMAFVTQIASATALVSVLAAFPGFFASWFTTEQTVIDIV
CHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
TRMMPIFVCGWGVFGIQLGAQCAFVGMGQAGQSVFLAVFRKVILLVPLALLLPHWLGVDG
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IFIAEPISDATSGMVAGLLFLITYRRIRRNLV
EEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AHTDALDSGLGVTPVPRLALTMSFPAIVAQAANASYTIIDRMFIGHIPEVGNAAMTGVG
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCHHHHHHH
ICFPILLAVTAFASLIGAGGAPRASIELGRGNFKKAERILGTSTAFLVVIALTLTAVLQS
HHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHH
VKRPILYAFGASDATIAYATDFITIYLIGTVFVQLTLGLNSFISAQGKTTVAMVSVLIGT
HCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
GASMVLDPVFIFVFGWGVRGAAAANVIAQLISTVWIVLFLSSGRSAIRLRPANIRIDRII
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCEEEHHHH
IPVLTLGLAPFIMQITECLINVVFNVGLQRYGGDDYVTSITIITSLIQVVGVLTGGFQQG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCHHHC
IQPIIGFNFGARNMRRVRQAIRMAFVTQIASATALVSVLAAFPGFFASWFTTEQTVIDIV
CHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHH
TRMMPIFVCGWGVFGIQLGAQCAFVGMGQAGQSVFLAVFRKVILLVPLALLLPHWLGVDG
HHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IFIAEPISDATSGMVAGLLFLITYRRIRRNLV
EEEECCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA