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The map label for this gene is yfbQ [C]

Identifier: 213691974

GI number: 213691974

Start: 1277945

End: 1279420

Strand: Direct

Name: yfbQ [C]

Synonym: Blon_1092

Alternate gene names: 213691974

Gene position: 1277945-1279420 (Clockwise)

Preceding gene: 213691973

Following gene: 213691975

Centisome position: 45.11

GC content: 62.2

Gene sequence:

>1476_bases
ATGAACAGCAGGGGACTGAAGCAGGTCGATTTGGTGCACGCCGCCGAACATCGTGGCGTAAAGATGGGCAAGAGCCACAT
CAGCCAATACGTGGCCGGCAAGACCATGCCCCGCGAGGACGTGCTCGAATTCCTGGCCAGCGAACTGGACGTCGACGCGA
ACTGGCTGCGCGGCGAGGAATCATCCGCTCCCTCCAATGGCGACGCGGCACCGGAGGGAGCCGGGCCGCGGACGGACGAT
GGGACCGCGCCGGCGCGCCGGCGTACCTTCGGCAAATCGCACAAGCTTGACAACGTGCTCTACGACGTGCGCGGCCCGGT
CGCCGACGAGGCGATGCGCATGGAGGCCAACGGCACCCACATCCTGAAATTGAACATCGGCAATCCGGCACCCTTCGGCT
TCCGCACGCCGGACGAAGTCGTCTACGACATGGCCCACCAGCTCACCGACACCGAAGGCTACTCGCCGTCCAAGGGCCTG
TTCTCCGCGCGCAAGGCCATCATGCAGTACGCGCAGCTGAAGAACATCCCGAACGTCACCATCGACGACATCTACACCGG
CAACGGCGTCAGCGAGCTCATCAACCTGTCCATGTCCGCGCTGCTCGACACCGGCGACGAAGTGCTCGTGCCCTCCCCGG
ACTACCCGCTGTGGACCGCCTGCGTGAACCTGGCCGGCGGCACCGCCGTGCACTACCTGTGCGACGAACAGTCCGAATGG
TATCCGGACATCGACGACATCCGCTCCAAGATCACCAGCAACACCAAGGCGATTGTCATCATCAACCCGAACAACCCCAC
CGGCGCACTTTACCCAAAGGAAGTGCTCCAGCAGATCGTCGACATCGCGCGCGAACGCCGGCTCATCATCTTCTCCGACG
AGATCTACGACCGTCTCGTCATGGACGGCCTGCAGCACGTCTCCATCGCCTCGATGGCCCCGGACCTGTTCTGCGTGACC
TTCTCCGGCCTGTCGAAATCGCACATGATCGCCGGCTACCGCATCGGCTGGATGATTTTGTCCGGCAACAAGCGCATCGC
CAAGGATTACATCGAAGGCCTCAACATGCTCGCCAACATGCGCATGTGCTCGAACGTGCCCGCCCAGTCCGTGGTGCAGA
CCGCGCTCGGCGGACACCAGAGCGTCAAGGACTATCTCGTTCCCGGCGGCCGCGTGTATGACCAGCGCGATCTCGTCTAC
GACATGCTCAACGCCATCCCTGGCATCAGCGCCGTTAAGCCCAAGGCCGCGTTCTACATCTTCCCGAAGATCGACGTCAA
GCGGTTCAACATTCACTCGGATGAGCAGTTCGCGCTCGATCTGCTGCATGAAAAGCACATCCTCATCAGCCATGGCGGTG
CGTTCAACTGGCGGCATCCCGACCACTTCCGTGTGGTGTACCTGCCGCGCATAGGCATGCTGCACGAAACCATGGAGGAG
CTCGCCGACTTCTTCAGCTACTACCGGCAGAACTGA

Upstream 100 bases:

>100_bases
GAGTATGCTTTGAACCGTTGTTCAAAAGATAAATTGAACTCCCGGTTGGAGGCATAAGGATATGAGCGTATCGGTGTTTG
CGGAACGTCTGCGCAATGCG

Downstream 100 bases:

>100_bases
CCCATGGCGCATACAGACGCACTTGATTCAGGGCTGGGCGTCACGCCGGTGCCCCGTCTGGCCCTCACCATGTCGTTCCC
CGCCATCGTGGCGCAGGCGG

Product: bifunctional HTH-domain containing protein/aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MNSRGLKQVDLVHAAEHRGVKMGKSHISQYVAGKTMPREDVLEFLASELDVDANWLRGEESSAPSNGDAAPEGAGPRTDD
GTAPARRRTFGKSHKLDNVLYDVRGPVADEAMRMEANGTHILKLNIGNPAPFGFRTPDEVVYDMAHQLTDTEGYSPSKGL
FSARKAIMQYAQLKNIPNVTIDDIYTGNGVSELINLSMSALLDTGDEVLVPSPDYPLWTACVNLAGGTAVHYLCDEQSEW
YPDIDDIRSKITSNTKAIVIINPNNPTGALYPKEVLQQIVDIARERRLIIFSDEIYDRLVMDGLQHVSIASMAPDLFCVT
FSGLSKSHMIAGYRIGWMILSGNKRIAKDYIEGLNMLANMRMCSNVPAQSVVQTALGGHQSVKDYLVPGGRVYDQRDLVY
DMLNAIPGISAVKPKAAFYIFPKIDVKRFNIHSDEQFALDLLHEKHILISHGGAFNWRHPDHFRVVYLPRIGMLHETMEE
LADFFSYYRQN

Sequences:

>Translated_491_residues
MNSRGLKQVDLVHAAEHRGVKMGKSHISQYVAGKTMPREDVLEFLASELDVDANWLRGEESSAPSNGDAAPEGAGPRTDD
GTAPARRRTFGKSHKLDNVLYDVRGPVADEAMRMEANGTHILKLNIGNPAPFGFRTPDEVVYDMAHQLTDTEGYSPSKGL
FSARKAIMQYAQLKNIPNVTIDDIYTGNGVSELINLSMSALLDTGDEVLVPSPDYPLWTACVNLAGGTAVHYLCDEQSEW
YPDIDDIRSKITSNTKAIVIINPNNPTGALYPKEVLQQIVDIARERRLIIFSDEIYDRLVMDGLQHVSIASMAPDLFCVT
FSGLSKSHMIAGYRIGWMILSGNKRIAKDYIEGLNMLANMRMCSNVPAQSVVQTALGGHQSVKDYLVPGGRVYDQRDLVY
DMLNAIPGISAVKPKAAFYIFPKIDVKRFNIHSDEQFALDLLHEKHILISHGGAFNWRHPDHFRVVYLPRIGMLHETMEE
LADFFSYYRQN
>Mature_491_residues
MNSRGLKQVDLVHAAEHRGVKMGKSHISQYVAGKTMPREDVLEFLASELDVDANWLRGEESSAPSNGDAAPEGAGPRTDD
GTAPARRRTFGKSHKLDNVLYDVRGPVADEAMRMEANGTHILKLNIGNPAPFGFRTPDEVVYDMAHQLTDTEGYSPSKGL
FSARKAIMQYAQLKNIPNVTIDDIYTGNGVSELINLSMSALLDTGDEVLVPSPDYPLWTACVNLAGGTAVHYLCDEQSEW
YPDIDDIRSKITSNTKAIVIINPNNPTGALYPKEVLQQIVDIARERRLIIFSDEIYDRLVMDGLQHVSIASMAPDLFCVT
FSGLSKSHMIAGYRIGWMILSGNKRIAKDYIEGLNMLANMRMCSNVPAQSVVQTALGGHQSVKDYLVPGGRVYDQRDLVY
DMLNAIPGISAVKPKAAFYIFPKIDVKRFNIHSDEQFALDLLHEKHILISHGGAFNWRHPDHFRVVYLPRIGMLHETMEE
LADFFSYYRQN

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4507369, Length=388, Percent_Identity=27.0618556701031, Blast_Score=145, Evalue=8e-35,
Organism=Homo sapiens, GI19263340, Length=371, Percent_Identity=25.3369272237197, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI215599424, Length=371, Percent_Identity=25.3369272237197, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI4885351, Length=452, Percent_Identity=23.6725663716814, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI95147551, Length=208, Percent_Identity=28.3653846153846, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI169881279, Length=208, Percent_Identity=28.3653846153846, Blast_Score=96, Evalue=9e-20,
Organism=Homo sapiens, GI56713254, Length=154, Percent_Identity=33.1168831168831, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI56713256, Length=154, Percent_Identity=33.1168831168831, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI169881281, Length=104, Percent_Identity=33.6538461538462, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI1788627, Length=399, Percent_Identity=59.1478696741855, Blast_Score=525, Evalue=1e-150,
Organism=Escherichia coli, GI1788722, Length=416, Percent_Identity=27.1634615384615, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786816, Length=301, Percent_Identity=21.5946843853821, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17567663, Length=370, Percent_Identity=31.3513513513514, Blast_Score=174, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI71981209, Length=487, Percent_Identity=23.8193018480493, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17567369, Length=360, Percent_Identity=26.1111111111111, Blast_Score=95, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71994476, Length=251, Percent_Identity=27.0916334661355, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI71994472, Length=251, Percent_Identity=27.0916334661355, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI71981215, Length=313, Percent_Identity=24.9201277955272, Blast_Score=78, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320317, Length=383, Percent_Identity=27.4151436031332, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6323118, Length=378, Percent_Identity=26.1904761904762, Blast_Score=117, Evalue=6e-27,
Organism=Saccharomyces cerevisiae, GI6322401, Length=317, Percent_Identity=25.5520504731861, Blast_Score=94, Evalue=4e-20,
Organism=Drosophila melanogaster, GI18859735, Length=386, Percent_Identity=27.720207253886, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24641770, Length=502, Percent_Identity=25.4980079681275, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24641760, Length=502, Percent_Identity=25.4980079681275, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24641768, Length=502, Percent_Identity=25.4980079681275, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24641766, Length=502, Percent_Identity=25.4980079681275, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24641764, Length=502, Percent_Identity=25.4980079681275, Blast_Score=117, Evalue=3e-26,
Organism=Drosophila melanogaster, GI45551451, Length=502, Percent_Identity=25.4980079681275, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28573069, Length=167, Percent_Identity=26.9461077844311, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24646114, Length=167, Percent_Identity=26.9461077844311, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28573067, Length=167, Percent_Identity=26.9461077844311, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28573065, Length=167, Percent_Identity=26.9461077844311, Blast_Score=86, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 54715; Mature: 54715

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSRGLKQVDLVHAAEHRGVKMGKSHISQYVAGKTMPREDVLEFLASELDVDANWLRGEE
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHCCCCC
SSAPSNGDAAPEGAGPRTDDGTAPARRRTFGKSHKLDNVLYDVRGPVADEAMRMEANGTH
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHCCCCCHHHHHEEECCCCE
ILKLNIGNPAPFGFRTPDEVVYDMAHQLTDTEGYSPSKGLFSARKAIMQYAQLKNIPNVT
EEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
IDDIYTGNGVSELINLSMSALLDTGDEVLVPSPDYPLWTACVNLAGGTAVHYLCDEQSEW
CCCEECCCCHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHCCCCEEEEEECCCCCC
YPDIDDIRSKITSNTKAIVIINPNNPTGALYPKEVLQQIVDIARERRLIIFSDEIYDRLV
CCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEECHHHHHHHH
MDGLQHVSIASMAPDLFCVTFSGLSKSHMIAGYRIGWMILSGNKRIAKDYIEGLNMLANM
HHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHH
RMCSNVPAQSVVQTALGGHQSVKDYLVPGGRVYDQRDLVYDMLNAIPGISAVKPKAAFYI
HHHCCCCHHHHHHHHHCCHHHHHHHCCCCCCEECHHHHHHHHHHHCCCCCCCCCCEEEEE
FPKIDVKRFNIHSDEQFALDLLHEKHILISHGGAFNWRHPDHFRVVYLPRIGMLHETMEE
EECCEEEEECCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHH
LADFFSYYRQN
HHHHHHHHHCC
>Mature Secondary Structure
MNSRGLKQVDLVHAAEHRGVKMGKSHISQYVAGKTMPREDVLEFLASELDVDANWLRGEE
CCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCHHCCCCC
SSAPSNGDAAPEGAGPRTDDGTAPARRRTFGKSHKLDNVLYDVRGPVADEAMRMEANGTH
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHHHHHCCCCCHHHHHEEECCCCE
ILKLNIGNPAPFGFRTPDEVVYDMAHQLTDTEGYSPSKGLFSARKAIMQYAQLKNIPNVT
EEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
IDDIYTGNGVSELINLSMSALLDTGDEVLVPSPDYPLWTACVNLAGGTAVHYLCDEQSEW
CCCEECCCCHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHCCCCEEEEEECCCCCC
YPDIDDIRSKITSNTKAIVIINPNNPTGALYPKEVLQQIVDIARERRLIIFSDEIYDRLV
CCCHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHCCEEEEECHHHHHHHH
MDGLQHVSIASMAPDLFCVTFSGLSKSHMIAGYRIGWMILSGNKRIAKDYIEGLNMLANM
HHHHHHHHHHHCCCCEEEEEECCCCCCCEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHH
RMCSNVPAQSVVQTALGGHQSVKDYLVPGGRVYDQRDLVYDMLNAIPGISAVKPKAAFYI
HHHCCCCHHHHHHHHHCCHHHHHHHCCCCCCEECHHHHHHHHHHHCCCCCCCCCCEEEEE
FPKIDVKRFNIHSDEQFALDLLHEKHILISHGGAFNWRHPDHFRVVYLPRIGMLHETMEE
EECCEEEEECCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHH
LADFFSYYRQN
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]